The function of scavenger receptors expressed by macrophages and their rolein the regulation of inflammation

Microbes and Infection

Volumn 3, Issue 2, 2001, Pages 149-159

  Peiser, Leanne ^a   Gordon, Siamon ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Inflammation; LPS; Scavenger receptor

Indexed keywords

HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; LIGAND; LOW DENSITY LIPOPROTEIN; SCAVENGER RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANIMAL CELL; ANTIGEN PRESENTATION; APOPTOSIS; ATHEROSCLEROSIS; CELL ADHESION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOCYTOSIS; FOREIGN BODY; HOST CELL; HUMAN; HUMAN CELL; IMMUNITY; INFLAMMATION; LIGAND BINDING; MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; NONHUMAN; PATHOGENESIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REVIEW; TISSUE INJURY;

EID: 0035092052     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(00)01362-9     Document Type: Review

References (109)

1. Recent progress in defining the role of scavenger receptors in lipid transport, atherosclerosis and host defence
2. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
3. The other side of scavenger receptors: Pattern recognition for host defense
4. Charting the fate of the "good cholesterol": Identification and characterization of the high-density lipoprotein receptor SR-BI
5. The role of scavenger receptors in the innate immune system
6. Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP)
7. Platelet adhesion to collagen in individuals lacking glycoprotein IV
8. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis
9. CD36 is a receptor for oxidized low density lipoprotein
10. Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors
11. Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end products of the Maillard reaction
12. Macrophage class A scavenger receptor-mediated phagocytosis of Escherichia coli: Role of cell heterogeneity, microbial strain, and culture conditions in vitro
13. The type I macrophage scavenger receptor binds to Gram-positive bacteria and recognizes lipoteichoic acid
14. Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages
15. Recognition and plasma clearance of endotoxin by scavenger receptors
16. Influence of lipoteichoic acid structure on recognition by the macrophage scavenger receptor
17. Secreted extracellular domains of macrophage scavenger receptors form elongated trimers which specifically bind crocidolite asbestos
18. Role of the scavenger receptor MARCO in alveolar macrophage binding of unopsonized environmental particles
19. Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils
20. Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II
21. Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors
22. Human macrophage scavenger receptors: Primary structure, expression, and localization in atherosclerotic lesions
23. Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells
24. A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake
25. Molecular characterization of a human scavenger receptor, human MARCO
26. The histidine interruption of an alpha-helical coiled coil allosterically mediates a pH-dependent ligand dissociation from macrophage scavenger receptors
27. The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands
28. Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain
29. Structures of class A macrophage scavenger receptors. Electron microscopic study of flexible, multidomain, fibrous proteins and determination of the disulfide bond pattern of the scavenger receptor cysteine-rich domain
30. Crystal structure of a scavenger receptor cysteine-rich domain sheds light on an ancient superfamily
31. Structure of the human macrophage MARCO receptor and characterization of its bacteria-binding region
32. A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains
33. Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM)
34. The processing of ligands by the class A scavenger receptor is dependent on signal information located in the cytoplasmic domain
35. Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors
36. Functional and possible physical association of scavenger receptor with cytoplasmic tyrosine kinase Lyn in monocytic THP-1-derived macrophages
37. Mechanisms of phagocytosis in macrophages
38. Murine macrophage scavenger receptor: In vivo expression and function as receptor for macrophage adhesion in lymphoid and non-lymphoid organs
39. Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo
40. Expression cloning of SR-BI, a CD36-related class B scavenger receptor
41. Alternative forms of the scavenger receptor BI (SR-BI)
42. Srb1 maps to mouse chromosome 5 in a region harboring putative QTLs for plasma lipoprotein levels
43. Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1
44. SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells
45. Characterization of CLA-1, a human homologue of rodent scavenger receptor BI, as a receptor for high density lipoprotein and apoptotic thymocytes
46. Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells
47. Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila
48. The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain
49. Regulated expression of CD36 during monocyte-to-macrophage differentiation: Potential role of CD36 in foam cell formation
50. The "best" of cholesterols, the "worst" of cholesterols: A tale of two receptors
51. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
52. Lipopolysaccharide inhibits the expression of the scavenger receptor Cla-1 in human monocytes and macrophages
53. Lipopolysaccharide stimulation of RAW 264.7 macrophages induces lipid accumulation and foam cell formation
54. Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: Lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein
55. Modulation of immunogenicity and antigenicity of proteins by maleylation to target scavenger receptors on macrophages
56. MHC class I-restricted presentation of maleylated protein binding to scavenger receptors
57. Modulation of T cell cytokine profiles and peptide-MHC complex availability in vivo by delivery to scavenger receptors via antigen maleylation
58. The macrophage scavenger receptor type A directs modified proteins to antigen presentation
59. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo
60. Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor
61. The role of scavenger receptor class A in the adhesion of cells is dependent on cell type and cellular activation state
62. Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils
63. Scavenger receptors: Diverse activities and promiscuous binding of polyanionic ligands
64. CD36 directly mediates cytoadherence ofPlasmodium falciparumparasitized erythrocytes
65. Atherosclerosis is an inflammatory disease
66. 2
67. Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro
68. Protection from lethal Gram-positive infection by macrophage scavenger receptor-dependent phagocytosis
69. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection
70. Macrophage scavenger receptor MARCO: In vitro and in vivo regulation and involvement in the anti-bacterial host defense
71. Oxidized low density lipoproteins alter macrophage lipid uptake, apoptosis, viability and nitric oxide synthesis
72. Scavenger receptors may regulate nitric oxide production from macrophages stimulated by LPS
73. Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism
74. The interleukin-12/interleukin-12-receptor system: Role in normal and pathologic immune responses
75. Selective suppression of interleukin-12 induction after macrophage receptor ligation
76. Lipopolysaccharide induces scavenger receptor A expression in mouse macrophages: A divergent response relative to human THP-1 monocyte/macrophages
77. Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS
78. The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock
79. Inhibition of macrophage scavenger receptor activity by tumor necrosis factor-alpha is transcriptionally and post-transcriptionally regulat
80. Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages
81. Prevention of endotoxin-induced monokine release by human low- and high-density lipoproteins and by apolipoprotein A-I
82. New function for high density lipoproteins. Their participation in intravascular reactions of bacterial lipopolysaccharides
83. Reconstituted high-density lipoprotein neutralizes Gram-negative bacterial lipopolysaccharides in human whole blood
84. Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia
85. PAR-gamma agonists inhibit production of monocyte inflammatory cytokines
86. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
87. Oidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
88. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
89. CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors
90. The SRCR superfamily: A family reminiscent of the Ig superfamily
91. Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli
92. Cyclophilin C-associated protein: A normal secreted glycoprotein that down-modulates endotoxin and proinflammatory responses in vivo
93. Alzheimer's disease and inflammation: A review of cellular and therapeutic mechanisms
94. Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis
95. Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis
96. Optimal conditions for proliferation of bone marrow-derived mouse macrophages in culture: The roles of CSF-1, serum, Ca2+, and adherence
97. A scavenger receptor up-regulation in smooth muscle cells by oxidized low density lipoprotein. Enhancement by calcium flux and concurrent cyclooxygenase-2 up-regulation
98. The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2 microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis
99. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
100. Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease
101. Recognizing death: The phagocytosis of apoptotic cells
102. Interaction of phagocytes with apoptotic cells leads to production of pro-inflammatory cytokines
103. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
104. SRB1, a class B scavenger receptor, recognizes both negatively charged liposomes and apoptotic cells
105. Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells
106. CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis
107. Apoptotic thymocyte clearance in scavenger receptor class A-deficient mice is apparently normal
108. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
109. Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages