메뉴 건너뛰기




Volumn 76, Issue 4, 2011, Pages 397-404

White matter synapses: Form, function, and dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BEPRIDIL; CHLORPHENIRAMINE MALEATE PLUS PHENYLEPHRINE; MEMANTINE; NITRENDIPINE; PERAMPANEL; PREGABALIN; TOPIRAMATE;

EID: 79251550472     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3182088273     Document Type: Review
Times cited : (50)

References (60)
  • 1
    • 0030894007 scopus 로고    scopus 로고
    • Expression of ionotropic glutamate receptor subunits in glial cells of the hippocampal CA1 area following transient forebrain ischemia
    • Gottlieb M, Matute C. Expression of ionotropic glutamate receptor subunits in glial cells of the hippocampal CA1 area following transient forebrain ischemia. J Cereb Blood Flow Metab 1997;17:290-300.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 290-300
    • Gottlieb, M.1    Matute, C.2
  • 2
    • 0034636493 scopus 로고    scopus 로고
    • Glutamater-gic synapses on oligodendrocyte precursor cells in the hippocampus
    • Bergles DE, Roberts JD, Somogyi P, Jahr CE. Glutamater-gic synapses on oligodendrocyte precursor cells in the hippocampus. Nature 2000;405:187-191.
    • (2000) Nature , vol.405 , pp. 187-191
    • Bergles, D.E.1    Roberts, J.D.2    Somogyi, P.3    Jahr, C.E.4
  • 3
    • 33644520285 scopus 로고    scopus 로고
    • NMDA receptors mediate calcium accumulation in myelin during chemical isch-aemia
    • Micu I, Jiang Q, Coderre E, et al. NMDA receptors mediate calcium accumulation in myelin during chemical isch-aemia. Nature 2006;439:988-992.
    • (2006) Nature , vol.439 , pp. 988-992
    • Micu, I.1    Jiang, Q.2    Coderre, E.3
  • 4
    • 29244483141 scopus 로고    scopus 로고
    • NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
    • Salter MG, Fern R. NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury. Nature 2005;438:1167-1171.
    • (2005) Nature , vol.438 , pp. 1167-1171
    • Salter, M.G.1    Fern, R.2
  • 5
    • 29244440745 scopus 로고    scopus 로고
    • NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
    • Karadottir R, Cavelier P, Bergersen LH, Attwell D. NMDA receptors are expressed in oligodendrocytes and activated in ischaemia. Nature 2005;438:1162-1166.
    • (2005) Nature , vol.438 , pp. 1162-1166
    • Karadottir, R.1    Cavelier, P.2    Bergersen, L.H.3    Attwell, D.4
  • 6
    • 34447625042 scopus 로고    scopus 로고
    • The sequence of events that underlie quantal transmission at central gluta-matergic synapses
    • Lisman JE, Raghavachari S, Tsien RW. The sequence of events that underlie quantal transmission at central gluta-matergic synapses. Nat Rev Neurosci 2007;8:597-609.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 597-609
    • Lisman, J.E.1    Raghavachari, S.2    Tsien, R.W.3
  • 7
    • 33846424598 scopus 로고    scopus 로고
    • Hypoxia-ischemia preferentially triggers glutamate depletion from oligoden-droglia and axons in perinatal cerebral white matter
    • Back SA, Craig A, Kayton RJ, et al. Hypoxia-ischemia preferentially triggers glutamate depletion from oligoden-droglia and axons in perinatal cerebral white matter. J Cereb Blood Flow Metab 2006;27:334-347.
    • (2006) J Cereb Blood Flow Metab , vol.27 , pp. 334-347
    • Back, S.A.1    Craig, A.2    Kayton, R.J.3
  • 8
    • 0027374999 scopus 로고
    • Calcium signaling of glial cells along mammalian axons
    • Kriegler S, Chiu SY. Calcium signaling of glial cells along mammalian axons. J Neurosci 1993;13:4229-4245.
    • (1993) J Neurosci , vol.13 , pp. 4229-4245
    • Kriegler, S.1    Chiu, S.Y.2
  • 10
    • 51749112285 scopus 로고    scopus 로고
    • Vesicular apparatus, including functional calcium channels, are present in developing rodent optic nerve axons and are required for normal node of Ranvier formation
    • Alix JJ, Dolphin AC, Fern R. Vesicular apparatus, including functional calcium channels, are present in developing rodent optic nerve axons and are required for normal node of Ranvier formation. J Physiol 2008;586:4069-4089.
    • (2008) J Physiol , vol.586 , pp. 4069-4089
    • Alix, J.J.1    Dolphin, A.C.2    Fern, R.3
  • 11
    • 0029942914 scopus 로고    scopus 로고
    • Calcium channel blockers and transmitter release at the normal human neuromuscular junction
    • Protti DA, Reisin R, Mackinley TA, Uchitel OD. Calcium channel blockers and transmitter release at the normal human neuromuscular junction. Neurology 1996;46:1391-1396.
    • (1996) Neurology , vol.46 , pp. 1391-1396
    • Protti, D.A.1    Reisin, R.2    MacKinley, T.A.3    Uchitel, O.D.4
  • 12
    • 73349135292 scopus 로고    scopus 로고
    • Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2-glia
    • Hamilton N, Vayro S, Wigley R, Butt AM. Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2-glia. Glia 2010;58:66-79.
    • (2010) Glia , vol.58 , pp. 66-79
    • Hamilton, N.1    Vayro, S.2    Wigley, R.3    Butt, A.M.4
  • 13
  • 14
    • 77649192116 scopus 로고    scopus 로고
    • Adult-born SVZ progenitors receive transient synapses during re-myelination in corpus callosum
    • Etxeberria A, Mangin J-M, Aguirre A, Gallo V. Adult-born SVZ progenitors receive transient synapses during re-myelination in corpus callosum. Nat Neurosci 2010;13: 287-289.
    • (2010) Nat Neurosci , vol.13 , pp. 287-289
    • Etxeberria, A.1    Mangin, J.-M.2    Aguirre, A.3    Gallo, V.4
  • 15
    • 77949407878 scopus 로고    scopus 로고
    • Excitability and synaptic communication within the oligodendrocyte lineage
    • De Biase LM, Nishiyama A, Bergles DE. Excitability and synaptic communication within the oligodendrocyte lineage. J Neurosci 2010;30:3600-3611.
    • (2010) J Neurosci , vol.30 , pp. 3600-3611
    • De Biase, L.M.1    Nishiyama, A.2    Bergles, D.E.3
  • 16
    • 77951252402 scopus 로고    scopus 로고
    • NG2-positive glia in the human central nervous system
    • Staugaitis SM, Trapp BD. NG2-positive glia in the human central nervous system. Neuron Glia Biol 2009:1-10.
    • (2009) Neuron Glia Biol , pp. 1-10
    • Staugaitis, S.M.1    Trapp, B.D.2
  • 17
    • 59149096417 scopus 로고    scopus 로고
    • Effects of glutamate receptor activation on NG2-glia in the rat optic nerve
    • Hamilton N, Hubbard PS, Butt AM. Effects of glutamate receptor activation on NG2-glia in the rat optic nerve. J Anat 2009;214:208-218.
    • (2009) J Anat , vol.214 , pp. 208-218
    • Hamilton, N.1    Hubbard, P.S.2    Butt, A.M.3
  • 18
    • 38849095193 scopus 로고    scopus 로고
    • NG2 cells generate both oligodendrocytes and gray matter astrocytes
    • Zhu X, Bergles DE, Nishiyama A. NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development 2008;135:145-157.
    • (2008) Development , vol.135 , pp. 145-157
    • Zhu, X.1    Bergles, D.E.2    Nishiyama, A.3
  • 19
    • 0030455844 scopus 로고    scopus 로고
    • Functional N-methyl-D-aspartate receptors in O-2A glial precursor cells: A critical role in regulating polysialic acid-neural cell adhesion molecule expression and cell migration
    • Wang C, Pralong WF, Schulz MF, et al. Functional N-methyl-D-aspartate receptors in O-2A glial precursor cells: a critical role in regulating polysialic acid-neural cell adhesion molecule expression and cell migration. J Cell Biol 1996;135:1565-1581.
    • (1996) J Cell Biol , vol.135 , pp. 1565-1581
    • Wang, C.1    Pralong, W.F.2    Schulz, M.F.3
  • 20
    • 0014189193 scopus 로고
    • Visual and non-visual factors in the centripetal stimulation of postnatal growth of the visual centers in mice
    • Gyllensten L, Malmfors T, Norrlin-Grettve ML. Visual and non-visual factors in the centripetal stimulation of postnatal growth of the visual centers in mice. J Comp Neurol 1967;131:549-557.
    • (1967) J Comp Neurol , vol.131 , pp. 549-557
    • Gyllensten, L.1    Malmfors, T.2    Norrlin-Grettve, M.L.3
  • 21
    • 33644860333 scopus 로고    scopus 로고
    • Astrocytes promote myelination in response to electrical impulses
    • Ishibashi T, Dakin KA, Stevens B, et al. Astrocytes promote myelination in response to electrical impulses. Neuron 2006;49:823-832.
    • (2006) Neuron , vol.49 , pp. 823-832
    • Ishibashi, T.1    Dakin, K.A.2    Stevens, B.3
  • 22
    • 0037028061 scopus 로고    scopus 로고
    • Adeno-sine: A neuron-glial transmitter promoting myelination in the CNS in response to action potentials
    • Stevens B, Porta S, Haak LL, Gallo V, Fields RD. Adeno-sine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials. Neuron 2002; 36:855-868.
    • (2002) Neuron , vol.36 , pp. 855-868
    • Stevens, B.1    Porta, S.2    Haak, L.L.3    Gallo, V.4    Fields, R.D.5
  • 23
    • 27644458332 scopus 로고    scopus 로고
    • Extensive piano practicing has regionally specific effects on white matter development
    • Bengtsson SL, Nagy Z, Skare S, Forsman L, Forssberg H, Ullen F. Extensive piano practicing has regionally specific effects on white matter development. Nat Neurosci 2005; 8:1148-1150.
    • (2005) Nat Neurosci , vol.8 , pp. 1148-1150
    • Bengtsson, S.L.1    Nagy, Z.2    Skare, S.3    Forsman, L.4    Forssberg, H.5    Ullen, F.6
  • 25
    • 57449101499 scopus 로고    scopus 로고
    • Oligodendrocytes changing the rules: Action potentials in glia and oligodendrocytes controlling action potentials
    • Fields RD. Oligodendrocytes changing the rules: action potentials in glia and oligodendrocytes controlling action potentials. Neuroscientist 2008;14:540-543.
    • (2008) Neuroscientist , vol.14 , pp. 540-543
    • Fields, R.D.1
  • 26
    • 72949104156 scopus 로고    scopus 로고
    • Glutamate receptor-mediated ischemic injury of premyelinated central axons
    • Alix JJ, Fern R. Glutamate receptor-mediated ischemic injury of premyelinated central axons. Ann Neurol 2009;66: 682-693.
    • (2009) Ann Neurol , vol.66 , pp. 682-693
    • Alix, J.J.1    Fern, R.2
  • 27
    • 45849133831 scopus 로고    scopus 로고
    • Diffuse axonal injury in periventricular leukomalacia as determined by apoptotic marker fractin
    • Haynes RL, Billiards SS, Borenstein NS, Volpe JJ, Kinney HC. Diffuse axonal injury in periventricular leukomalacia as determined by apoptotic marker fractin. Pediatr Res 2008;63:656-661.
    • (2008) Pediatr Res , vol.63 , pp. 656-661
    • Haynes, R.L.1    Billiards, S.S.2    Borenstein, N.S.3    Volpe, J.J.4    Kinney, H.C.5
  • 28
    • 37349030194 scopus 로고    scopus 로고
    • Testing NMDA receptor block as a therapeutic strategy for reducing ischaemic damage to CNS white matter
    • Bakiri Y, Hamilton NB, Karadottir R, Attwell D. Testing NMDA receptor block as a therapeutic strategy for reducing ischaemic damage to CNS white matter. Glia 2008;56: 233-240.
    • (2008) Glia , vol.56 , pp. 233-240
    • Bakiri, Y.1    Hamilton, N.B.2    Karadottir, R.3    Attwell, D.4
  • 29
    • 2342662620 scopus 로고    scopus 로고
    • Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: A protective role for topiramate
    • Follett PL, Deng W, Dai W, et al. Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. J Neurosci 2004;24:4412-4420.
    • (2004) J Neurosci , vol.24 , pp. 4412-4420
    • Follett, P.L.1    Deng, W.2    Dai, W.3
  • 30
    • 0034671193 scopus 로고    scopus 로고
    • NBQX attenuates excitotoxic injury in developing white matter
    • Follett PL, Rosenberg PA, Volpe JJ, Jensen FE. NBQX attenuates excitotoxic injury in developing white matter. J Neurosci 2000;20:9235-9241.
    • (2000) J Neurosci , vol.20 , pp. 9235-9241
    • Follett, P.L.1    Rosenberg, P.A.2    Volpe, J.J.3    Jensen, F.E.4
  • 31
    • 0034625150 scopus 로고    scopus 로고
    • A universal scaling law between gray matter and white matter of cerebral cortex
    • Zhang K, Sejnowski TJ. A universal scaling law between gray matter and white matter of cerebral cortex. Proc Natl Acad Sci USA 2000;97:5621-5626.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5621-5626
    • Zhang, K.1    Sejnowski, T.J.2
  • 32
    • 77953025222 scopus 로고    scopus 로고
    • Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies
    • Ihara M, Polvikoski TM, Hall R, et al. Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies. Acta Neuropathol 2010;119:579-589.
    • (2010) Acta Neuropathol , vol.119 , pp. 579-589
    • Ihara, M.1    Polvikoski, T.M.2    Hall, R.3
  • 33
    • 0029087953 scopus 로고
    • Voltage-gated calcium channels in CNS white matter: Role in anoxic injury
    • Fern R, Ransom BR, Waxman SG. Voltage-gated calcium channels in CNS white matter: role in anoxic injury. J Neurophysiol 1995;74:369-377.
    • (1995) J Neurophysiol , vol.74 , pp. 369-377
    • Fern, R.1    Ransom, B.R.2    Waxman, S.G.3
  • 34
    • 0141750468 scopus 로고    scopus 로고
    • Depolarization-induced Ca2+ release in ischemic spinal cord white matter involves L-type Ca2+ channel activation of ryanodine receptors
    • Ouardouz M, Nikolaeva MA, Coderre E, et al. Depolarization-induced Ca2+ release in ischemic spinal cord white matter involves L-type Ca2+ channel activation of ryanodine receptors. Neuron 2003;40:53-63.
    • (2003) Neuron , vol.40 , pp. 53-63
    • Ouardouz, M.1    Nikolaeva, M.A.2    Coderre, E.3
  • 35
    • 62549152683 scopus 로고    scopus 로고
    • Glutamate receptors on myelinated spinal cord axons: I: GluR6 kainate receptors
    • Ouardouz M, Coderre E, Basak A, et al. Glutamate receptors on myelinated spinal cord axons: I: GluR6 kainate receptors. Ann Neurol 2009;65:151-159.
    • (2009) Ann Neurol , vol.65 , pp. 151-159
    • Ouardouz, M.1    Coderre, E.2    Basak, A.3
  • 36
    • 33750682614 scopus 로고    scopus 로고
    • Complex interplay between glutamate receptors and intracellular Ca2+ stores during ischaemia in rat spinal cord white matter
    • Ouardouz M, Malek S, Coderre E, Stys PK. Complex interplay between glutamate receptors and intracellular Ca2+ stores during ischaemia in rat spinal cord white matter. J Physiol 2006;577:191-204.
    • (2006) J Physiol , vol.577 , pp. 191-204
    • Ouardouz, M.1    Malek, S.2    Coderre, E.3    Stys, P.K.4
  • 37
    • 0035875713 scopus 로고    scopus 로고
    • AMPA/kainate receptor activation mediates hypoxic oligodendrocyte death and axonal injury in cerebral white matter
    • Tekkok SB, Goldberg MP. AMPA/kainate receptor activation mediates hypoxic oligodendrocyte death and axonal injury in cerebral white matter. J Neurosci 2001;21:4237-4248.
    • (2001) J Neurosci , vol.21 , pp. 4237-4248
    • Tekkok, S.B.1    Goldberg, M.P.2
  • 38
    • 62549113032 scopus 로고    scopus 로고
    • Glutamate receptors on myelinated spinal cord axons: II: AMPA and GluR5 receptors
    • Ouardouz M, Coderre E, Zamponi GW, et al. Glutamate receptors on myelinated spinal cord axons: II: AMPA and GluR5 receptors. Ann Neurol 2009;65:160-166.
    • (2009) Ann Neurol , vol.65 , pp. 160-166
    • Ouardouz, M.1    Coderre, E.2    Zamponi, G.W.3
  • 39
    • 33645095476 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
    • Lipton SA. Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat Rev Drug Discov 2006;5:160-170.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 160-170
    • Lipton, S.A.1
  • 40
    • 2542619146 scopus 로고    scopus 로고
    • Molecular changes in neurons in multiple sclerosis: Altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger
    • Craner MJ, Newcombe J, Black JA, Hartle C, Cuzner ML, Waxman SG. Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger. Proc Natl Acad Sci USA 2004;101:8168-8173.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8168-8173
    • Craner, M.J.1    Newcombe, J.2    Black, J.A.3    Hartle, C.4    Cuzner, M.L.5    Waxman, S.G.6
  • 41
    • 59349089207 scopus 로고    scopus 로고
    • Axons and multiple sclerosis
    • Alix JJ. Axons and multiple sclerosis. Mult Scler 2009;15: 278.
    • (2009) Mult Scler , vol.15 , pp. 278
    • Alix, J.J.1
  • 42
    • 0034987047 scopus 로고    scopus 로고
    • Distribution of a calcium channel subunit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis
    • Kornek B, Storch MK, Bauer J, et al. Distribution of a calcium channel subunit in dystrophic axons in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain 2001;124:1114-1124.
    • (2001) Brain , vol.124 , pp. 1114-1124
    • Kornek, B.1    Storch, M.K.2    Bauer, J.3
  • 43
    • 59949106172 scopus 로고    scopus 로고
    • Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis
    • Trapp BD, Stys PK. Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis. Lancet Neurol 2009;8:280-291.
    • (2009) Lancet Neurol , vol.8 , pp. 280-291
    • Trapp, B.D.1    Stys, P.K.2
  • 44
    • 0037122960 scopus 로고    scopus 로고
    • Pre-myelinating oligodendrocytes in chronic lesions of multiple sclerosis
    • Chang A, Tourtellotte WW, Rudick R, Trapp BD. Pre-myelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med 2002;346:165-173.
    • (2002) N Engl J Med , vol.346 , pp. 165-173
    • Chang, A.1    Tourtellotte, W.W.2    Rudick, R.3    Trapp, B.D.4
  • 45
    • 3543068828 scopus 로고    scopus 로고
    • Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis
    • Brand-Schieber E, Werner P. Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis. Exp Neurol 2004;189:5-9.
    • (2004) Exp Neurol , vol.189 , pp. 5-9
    • Brand-Schieber, E.1    Werner, P.2
  • 46
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune en-cephalomyelitis ameliorated by AMPA antagonists
    • Smith T, Groom A, Zhu B, Tukski L. Autoimmune en-cephalomyelitis ameliorated by AMPA antagonists. Nat Med 2000;6:62-66.
    • (2000) Nat Med , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Tukski, L.4
  • 47
    • 67049100685 scopus 로고    scopus 로고
    • Memantine induces reversible neurologic impairment in patients with MS
    • Villoslada P, Arrondo G, Sepulcre J, Alegre M, Artieda J. Memantine induces reversible neurologic impairment in patients with MS. Neurology 2009;72:1630-1633.
    • (2009) Neurology , vol.72 , pp. 1630-1633
    • Villoslada, P.1    Arrondo, G.2    Sepulcre, J.3    Alegre, M.4    Artieda, J.5
  • 48
    • 0346770038 scopus 로고    scopus 로고
    • Age-related myelin breakdown: A developmental model of cognitive decline and Alzheimer's disease
    • Bartzokis G. Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging 2004;25:5-18.
    • (2004) Neurobiol Aging , vol.25 , pp. 5-18
    • Bartzokis, G.1
  • 49
    • 61449120013 scopus 로고    scopus 로고
    • Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology
    • Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, Frazer ME, Bowers WJ. Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology. Glia 2009;57:54-65.
    • (2009) Glia , vol.57 , pp. 54-65
    • Desai, M.K.1    Sudol, K.L.2    Janelsins, M.C.3    Mastrangelo, M.A.4    Frazer, M.E.5    Bowers, W.J.6
  • 50
    • 53949093474 scopus 로고    scopus 로고
    • The functional organization and assembly of the axon initial segment
    • Ogawa Y, Rasband MN. The functional organization and assembly of the axon initial segment. Curr Opin Neuro-biol 2008;18:307-313.
    • (2008) Curr Opin Neuro-biol , vol.18 , pp. 307-313
    • Ogawa, Y.1    Rasband, M.N.2
  • 51
    • 56749091391 scopus 로고    scopus 로고
    • Longitudinal multi-modal imaging in mild to moderate Alzheimer disease: A pilot study with memantine
    • Schmidt R, Ropele S, Pendl B, et al. Longitudinal multi-modal imaging in mild to moderate Alzheimer disease: a pilot study with memantine. J Neurol Neurosurg Psychiatry 2008;79:1312-1317.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 1312-1317
    • Schmidt, R.1    Ropele, S.2    Pendl, B.3
  • 52
    • 0030771894 scopus 로고    scopus 로고
    • Huntingtin localization in brains of normal and Huntington's disease patients
    • Sapp E, Schwarz C, Chase K, et al. Huntingtin localization in brains of normal and Huntington's disease patients. Ann Neurol 1997;42:604-612.
    • (1997) Ann Neurol , vol.42 , pp. 604-612
    • Sapp, E.1    Schwarz, C.2    Chase, K.3
  • 53
    • 4644245086 scopus 로고    scopus 로고
    • In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease
    • Fennema-Notestine C, Archibald SL, Jacobson MW, et al. In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease. Neurology 2004;63: 989-995.
    • (2004) Neurology , vol.63 , pp. 989-995
    • Fennema-Notestine, C.1    Archibald, S.L.2    Jacobson, M.W.3
  • 54
    • 0042921188 scopus 로고    scopus 로고
    • Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release
    • Li H, Wyman T, Yu Z-X, Li S-H, Li X-J. Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release. Hum Mol Genet 2003;12:2021-2030.
    • (2003) Hum Mol Genet , vol.12 , pp. 2021-2030
    • Li, H.1    Wyman, T.2    Yu, Z.-X.3    Li, S.-H.4    Li, X.-J.5
  • 55
    • 0141750470 scopus 로고    scopus 로고
    • Disruption of axonal transport by loss of huntingtin or expression of pathogenic PolyQ proteins in Drosophila
    • Gunawardena S, Her L-S, Brusch RG, et al. Disruption of axonal transport by loss of huntingtin or expression of pathogenic PolyQ proteins in Drosophila. Neuron 2003; 40:25-40.
    • (2003) Neuron , vol.40 , pp. 25-40
    • Gunawardena, S.1    Her, L.-S.2    Brusch, R.G.3
  • 57
    • 0038643584 scopus 로고    scopus 로고
    • White matter changes in schizophrenia: Evidence for myelin-related dysfunction
    • Davis KL, Stewart DG, Friedman JI, et al. White matter changes in schizophrenia: evidence for myelin-related dysfunction. Arch Gen Psychiatry 2003;60:443-456.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 443-456
    • Davis, K.L.1    Stewart, D.G.2    Friedman, J.I.3
  • 58
    • 0034017019 scopus 로고    scopus 로고
    • Neuropathological abnormalities of the corpus callosum in schizophrenia: A diffusion tensor imaging study
    • Foong J, Maier M, Clark CA, Barker GJ, Miller DH, Ron MA. Neuropathological abnormalities of the corpus callosum in schizophrenia: a diffusion tensor imaging study. J Neurol Neurosurg Psychiatry 2000;68:242-244.
    • (2000) J Neurol Neurosurg Psychiatry , vol.68 , pp. 242-244
    • Foong, J.1    Maier, M.2    Clark, C.A.3    Barker, G.J.4    Miller, D.H.5    Ron, M.A.6
  • 59
    • 33646522416 scopus 로고    scopus 로고
    • Gene regulation by hypoxia and the neurodevelopmen-tal origin of schizophrenia
    • Schmidt-Kastner R, Van Os J, Steinbusch HWM, Schmitz C. Gene regulation by hypoxia and the neurodevelopmen-tal origin of schizophrenia. Schizophr Res 2006;84:253-271.
    • (2006) Schizophr Res , vol.84 , pp. 253-271
    • Schmidt-Kastner, R.1    Van Os, J.2    Hwm, S.3    Schmitz, C.4
  • 60
    • 2342512304 scopus 로고    scopus 로고
    • Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hip-pocampal formation in schizophrenia
    • Talbot K, Eidem WL, Tinsley CL, et al. Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hip-pocampal formation in schizophrenia. J Clin Invest 2004; 113:1353-1363.
    • (2004) J Clin Invest , vol.113 , pp. 1353-1363
    • Talbot, K.1    Eidem, W.L.2    Tinsley, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.