Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: Implications for the pathogenesis of steatohepatitis

American Journal of Physiology - Endocrinology and Metabolism

Volumn 300, Issue 2, 2011, Pages

  Macfarlane, David P ^a   Zou, Xiantong ^a   Andrew, Ruth ^a   Morton, Nicholas M ^b   Livingstone, Dawn E W ^a   Aucott, Rebecca L ^c   Nyirenda, Moffat J ^a   Iredale, John P ^c   Walker, Brian R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Choline deficient diet; De novo lipogenesis; Free fatty acids; Methionine and choline deficient diet; Nonalcoholic fatty liver disease; Steatohepatitis

Indexed keywords

ACETIC ACID; FATTY ACID; PALMITIC ACID; TYLOXAPOL;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; DIET; DILUTION; FATTY ACID METABOLISM; FOOD INTAKE; HEPATITIS; INSULIN RESISTANCE; LIPOGENESIS; LIVER CIRRHOSIS; LIVER INJURY; MALE; METHIONINE DEFICIENCY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONALCOHOLIC FATTY LIVER; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; STEATOSIS; VITAMIN DEFICIENCY;

ADIPOSE TISSUE; ANIMALS; CHOLINE DEFICIENCY; DIET; EATING; FATTY ACIDS; FATTY LIVER; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEPATITIS; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; KINETICS; LIPOGENESIS; LIVER; MALE; METABOLIC NETWORKS AND PATHWAYS; METHIONINE; MICE; MICE, INBRED C57BL; ORGAN SIZE; PALMITIC ACIDS; TRIGLYCERIDES;

EID: 79251542932     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00331.2010     Document Type: Article

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