메뉴 건너뛰기




Volumn 18, Issue 3, 2011, Pages 316-328

Quassinoids: From traditional drugs to new cancer therapeutics

Author keywords

Anticancer therapeutics; Quassinoids; Simaroubaceae; Tumor

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIMALARIAL AGENT; ANTIVIRUS AGENT; BRUCEA JAVANICA EXTRACT; BRUCEANTIN; BRUSATOL; CASPASE 3; CASPASE 8; CASPASE 9; DNA; EURYCOMA LONGIFOLIA EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MYC PROTEIN; QUASSINOID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RNA; VASCULOTROPIN;

EID: 79251517716     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986711794839205     Document Type: Article
Times cited : (67)

References (72)
  • 1
    • 0344994511 scopus 로고    scopus 로고
    • Novel antitumor agents from higher plants
    • Lee, K. H. Novel antitumor agents from higher plants. Med. Res. Rev., 1999, 19(6), 569-96.
    • (1999) Med. Res. Rev. , vol.19 , Issue.6 , pp. 569-596
    • Lee, K.H.1
  • 2
    • 77950400139 scopus 로고    scopus 로고
    • Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach
    • Lee, K. H. Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach. J. Nat. Prod., 2010, 73(3), 500-16.
    • (2010) J. Nat. Prod. , vol.73 , Issue.3 , pp. 500-516
    • Lee, K.H.1
  • 5
    • 67349190115 scopus 로고    scopus 로고
    • Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase
    • Lau, S. T.; Lin, Z. X.; Liao, Y.; Zhao, M.; Cheng, C. H.; Leung, P. S. Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase. Cancer Lett., 2009, 281(1), 42-52.
    • (2009) Cancer Lett. , vol.281 , Issue.1 , pp. 42-52
    • Lau, S.T.1    Lin, Z.X.2    Liao, Y.3    Zhao, M.4    Cheng, C.H.5    Leung, P.S.6
  • 6
    • 0021783508 scopus 로고
    • Quassinoid bitter principles. II
    • Polonsky, J. Quassinoid bitter principles. II. Fortschr. Chem. Org. Naturst., 1985, 47, 221-64.
    • (1985) Fortschr. Chem. Org. Naturst. , vol.47 , pp. 221-264
    • Polonsky, J.1
  • 7
    • 0037044569 scopus 로고    scopus 로고
    • Cancer chemopreventive effect of quassinoid derivatives. Introduction of sidechain to shinjulactone C for enhancement of inhibitory effect on Epstein-Barr virus activation
    • Tamura, S.; Fukamiya, N.; Okano, M.; Tokuda, H.; Aoi, W.; Mukainaka, T.; Nishino, H.; Tagahara, K.; Koike, K. Cancer chemopreventive effect of quassinoid derivatives. Introduction of sidechain to shinjulactone C for enhancement of inhibitory effect on Epstein-Barr virus activation. Cancer Lett., 2002, 185(1), 47-51.
    • (2002) Cancer Lett. , vol.185 , Issue.1 , pp. 47-51
    • Tamura, S.1    Fukamiya, N.2    Okano, M.3    Tokuda, H.4    Aoi, W.5    Mukainaka, T.6    Nishino, H.7    Tagahara, K.8    Koike, K.9
  • 9
    • 0018230762 scopus 로고
    • Plant antitumor agents. XVI. 6alpha-Senecioyloxy-chaparrinone, a new antileukemic quassinoid from Simaba multiflora
    • Wani, M. C.; Taylor, H. L.; Thompson, J. B.; Wall, M. E. Plant antitumor agents. XVI. 6alpha-Senecioyloxy-chaparrinone, a new antileukemic quassinoid from Simaba multiflora. Lloydia, 1978, 41(6), 578-83.
    • (1978) Lloydia , vol.41 , Issue.6 , pp. 578-583
    • Wani, M.C.1    Taylor, H.L.2    Thompson, J.B.3    Wall, M.E.4
  • 10
    • 11844255707 scopus 로고    scopus 로고
    • Biologically active quassinoids and their chemistry: Potential leads for drug design
    • Guo, Z.; Vangapandu, S.; Sindelar, R. W.; Walker, L. A.; Sindelar, R. D. Biologically active quassinoids and their chemistry: Potential leads for drug design. Curr. Med. Chem., 2005, 12(2), 173-90.
    • (2005) Curr. Med. Chem. , vol.12 , Issue.2 , pp. 173-190
    • Guo, Z.1    Vangapandu, S.2    Sindelar, R.W.3    Walker, L.A.4    Sindelar, R.D.5
  • 11
    • 63049119349 scopus 로고    scopus 로고
    • Chemical constituents of plants from the genus Brucea
    • Liu, J. H.; Jin, H. Z.; Zhang, W. D.; Yan, S. K.; Shen, Y. H. Chemical constituents of plants from the genus Brucea. Chem. Biodivers., 2009, 6(1), 57-70.
    • (2009) Chem. Biodivers. , vol.6 , Issue.1 , pp. 57-70
    • Liu, J.H.1    Jin, H.Z.2    Zhang, W.D.3    Yan, S.K.4    Shen, Y.H.5
  • 14
    • 49749115202 scopus 로고    scopus 로고
    • A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxiainducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation
    • Jin, X.; Jin, H. R.; Lee, D.; Lee, J. H.; Kim, S. K.; Lee, J. J. A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxiainducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation. Eur. J. Pharmacol., 2008, 592(1-3), 41-7.
    • (2008) Eur. J. Pharmacol. , vol.592 , Issue.1-3 , pp. 41-47
    • Jin, X.1    Jin, H.R.2    Lee, D.3    Lee, J.H.4    Kim, S.K.5    Lee, J.J.6
  • 15
    • 1442285458 scopus 로고    scopus 로고
    • Antitumor activity of bruceantin: An old drug with new promise
    • Cuendet, M.; Pezzuto, J. M. Antitumor activity of bruceantin: An old drug with new promise. J. Nat. Prod., 2004, 67(2), 269-72.
    • (2004) J. Nat. Prod. , vol.67 , Issue.2 , pp. 269-272
    • Cuendet, M.1    Pezzuto, J.M.2
  • 17
    • 0016845068 scopus 로고
    • The isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica
    • Kupchan, S. M.; Britton, R. W.; Lacadie, J. A.; Ziegler, M. F.; Sigel, C. W. The isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica. J. Org. Chem., 1975, 40(5), 648-54.
    • (1975) J. Org. Chem. , vol.40 , Issue.5 , pp. 648-654
    • Kupchan, S.M.1    Britton, R.W.2    Lacadie, J.A.3    Ziegler, M.F.4    Sigel, C.W.5
  • 18
    • 0032555437 scopus 로고    scopus 로고
    • Synthetic Studies on Quassinoids: Total Synthesis and Biological Evaluation of (+)-Des-Dchaparrinone
    • Grieco, P. A.; Speake, J. D. Synthetic Studies on Quassinoids: Total Synthesis and Biological Evaluation of (+)-Des-Dchaparrinone. J. Org. Chem., 1998, 63(17), 5929-5936.
    • (1998) J. Org. Chem. , vol.63 , Issue.17 , pp. 5929-5936
    • Grieco, P.A.1    Speake, J.D.2
  • 20
    • 67349260439 scopus 로고    scopus 로고
    • U2504 determines the species specificity of the A-site cleft antibiotics: The structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome
    • Gurel, G.; Blaha, G.; Moore, P. B.; Steitz, T. A. U2504 determines the species specificity of the A-site cleft antibiotics: The structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J. Mol. Biol., 2009, 389(1), 146-56.
    • (2009) J. Mol. Biol. , vol.389 , Issue.1 , pp. 146-156
    • Gurel, G.1    Blaha, G.2    Moore, P.B.3    Steitz, T.A.4
  • 22
    • 0020958892 scopus 로고
    • A Phase II study of Bruceantin (NSC-165, 563) in advanced malignant melanoma
    • Arseneau, J. C.; Wolter, J. M.; Kuperminc, M.; Ruckdeschel, J. C. A Phase II study of Bruceantin (NSC-165, 563) in advanced malignant melanoma. Invest. New Drugs, 1983, 1(3), 239-42.
    • (1983) Invest. New Drugs , vol.1 , Issue.3 , pp. 239-242
    • Arseneau, J.C.1    Wolter, J.M.2    Kuperminc, M.3    Ruckdeschel, J.C.4
  • 24
    • 0037879052 scopus 로고    scopus 로고
    • The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update
    • Ly, J. D.; Grubb, D. R.; Lawen, A. The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update. Apoptosis, 2003, 8(2), 115-28.
    • (2003) Apoptosis , vol.8 , Issue.2 , pp. 115-128
    • Ly, J.D.1    Grubb, D.R.2    Lawen, A.3
  • 25
    • 1442335376 scopus 로고    scopus 로고
    • Brusatol-induced HL-60 cell differentiation involves NF-kappaB activation
    • Cuendet, M.; Gills, J. J.; Pezzuto, J. M. Brusatol-induced HL-60 cell differentiation involves NF-kappaB activation. Cancer Lett., 2004, 206(1), 43-50.
    • (2004) Cancer Lett. , vol.206 , Issue.1 , pp. 43-50
    • Cuendet, M.1    Gills, J.J.2    Pezzuto, J.M.3
  • 26
    • 33144466315 scopus 로고    scopus 로고
    • C-Myc, genome instability, and tumorigenesis: The devil is in the details
    • Wade, M.; Wahl, G. M. c-Myc, genome instability, and tumorigenesis: The devil is in the details. Curr. Top. Microbiol. Immunol., 2006, 302, 169-203.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.302 , pp. 169-203
    • Wade, M.1    Wahl, G.M.2
  • 27
    • 0036849687 scopus 로고    scopus 로고
    • Brusatol-mediated induction of leukemic cell differentiation and G(1) arrest is associated with down-regulation of c-myc
    • Mata-Greenwood, E.; Cuendet, M.; Sher, D.; Gustin, D.; Stock, W.; Pezzuto, J. M. Brusatol-mediated induction of leukemic cell differentiation and G(1) arrest is associated with down-regulation of c-myc. Leukemia, 2002, 16(11), 2275-84.
    • (2002) Leukemia , vol.16 , Issue.11 , pp. 2275-2284
    • Mata-Greenwood, E.1    Cuendet, M.2    Sher, D.3    Gustin, D.4    Stock, W.5    Pezzuto, J.M.6
  • 28
    • 42949125901 scopus 로고    scopus 로고
    • Brucea javanica fruit induces cytotoxicity and apoptosis in pancreatic adenocarcinoma cell lines
    • Lau, S. T.; Lin, Z. X.; Zhao, M.; Leung, P. S. Brucea javanica fruit induces cytotoxicity and apoptosis in pancreatic adenocarcinoma cell lines. Phytother. Res., 2008, 22(4), 477-86.
    • (2008) Phytother. Res. , vol.22 , Issue.4 , pp. 477-486
    • Lau, S.T.1    Lin, Z.X.2    Zhao, M.3    Leung, P.S.4
  • 29
    • 0242635945 scopus 로고    scopus 로고
    • Three novel quassinoids, javanicolides A and B, and javanicoside A, from seeds of Brucea javanica
    • Kim, I. H.; R., S.; Y., H.; K, T. Three novel quassinoids, javanicolides A and B, and javanicoside A, from seeds of Brucea javanica. Tetrahedron, 2003, 59 (50), 9985-9989.
    • (2003) Tetrahedron , vol.59 , Issue.50 , pp. 9985-9989
    • Kim I.H.R.S.Y.H.K, T.1
  • 30
    • 76349122924 scopus 로고    scopus 로고
    • Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-kappaB signalling pathways in human pancreatic adenocarcinoma cells
    • Lau, S. T.; Lin, Z. X.; Leung, P. S. Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-kappaB signalling pathways in human pancreatic adenocarcinoma cells. Br. J. Cancer., 2010, 102(3), 583-93.
    • (2010) Br. J. Cancer. , vol.102 , Issue.3 , pp. 583-593
    • Lau, S.T.1    Lin, Z.X.2    Leung, P.S.3
  • 31
    • 76749088358 scopus 로고    scopus 로고
    • Pathological roles of MAPK signaling pathways in human diseases
    • Kim, E. K.; Choi, E. J. Pathological roles of MAPK signaling pathways in human diseases. Biochim. Biophys. Acta, 2010, 1802(4), 396-405.
    • (2010) Biochim. Biophys. Acta , vol.1802 , Issue.4 , pp. 396-405
    • Kim, E.K.1    Choi, E.J.2
  • 32
    • 33645999706 scopus 로고    scopus 로고
    • NF-kappaB and IKK as therapeutic targets in cancer
    • Kim, H. J.; Hawke, N.; Baldwin, A. S. NF-kappaB and IKK as therapeutic targets in cancer. Cell Death Differ., 2006, 13(5), 738-47.
    • (2006) Cell Death Differ. , vol.13 , Issue.5 , pp. 738-747
    • Kim, H.J.1    Hawke, N.2    Baldwin, A.S.3
  • 33
    • 1442274808 scopus 로고    scopus 로고
    • P38 MAP kinase: A convergence point in cancer therapy
    • Olson, J. M.; Hallahan, A. R. p38 MAP kinase: A convergence point in cancer therapy. Trends Mol. Med., 2004, 10(3), 125-9.
    • (2004) Trends Mol. Med. , vol.10 , Issue.3 , pp. 125-129
    • Olson, J.M.1    Hallahan, A.R.2
  • 34
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-kappaB signaling: Balancing life and death-A new approach to cancer therapy
    • Luo, J. L.; Kamata, H.; Karin, M. IKK/NF-kappaB signaling: Balancing life and death-a new approach to cancer therapy. J. Clin. Invest., 2005, 115(10), 2625-32.
    • (2005) J. Clin. Invest. , vol.115 , Issue.10 , pp. 2625-2632
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 36
    • 58149202128 scopus 로고    scopus 로고
    • Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
    • Baud, V.; Karin, M. Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. Nat. Rev. Drug Discov., 2009, 8(1), 33-40.
    • (2009) Nat. Rev. Drug Discov. , vol.8 , Issue.1 , pp. 33-40
    • Baud, V.1    Karin, M.2
  • 37
    • 0035688049 scopus 로고    scopus 로고
    • Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12- dimethylbenz [a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture
    • Mata-Greenwood, E.; Daeuble, J. F.; Grieco, P. A.; Dou, J.; McChesney, J. D.; Mehta, R. G.; Kinghorn, A. D.; Pezzuto, J. M. Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12- dimethylbenz [a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. J. Nat. Prod., 2001, 64(12), 1509-13.
    • (2001) J. Nat. Prod. , vol.64 , Issue.12 , pp. 1509-1513
    • Mata-Greenwood, E.1    Daeuble, J.F.2    Grieco, P.A.3    Dou, J.4    McChesney, J.D.5    Mehta, R.G.6    Kinghorn, A.D.7    Pezzuto, J.M.8
  • 38
    • 0030738677 scopus 로고    scopus 로고
    • Multidrug resistance: Molecular mechanisms and clinical relevance
    • Ling, V. Multidrug resistance: Molecular mechanisms and clinical relevance. Cancer Chemother. Pharmacol., 1997, 40(Suppl), S3-8.
    • (1997) Cancer Chemother. Pharmacol. , vol.40 , Issue.SUPPL.
    • Ling, V.1
  • 39
    • 4444322833 scopus 로고    scopus 로고
    • Multidrugresistant cancer cell susceptibility to cytotoxic quassinoids, and cancer chemopreventive effects of quassinoids and canthin alkaloids
    • Murakami, C.; Fukamiya, N.; Tamura, S.; Okano, M.; Bastow, K. F.; Tokuda, H.; Mukainaka, T.; Nishino, H.; Lee, K. H. Multidrugresistant cancer cell susceptibility to cytotoxic quassinoids, and cancer chemopreventive effects of quassinoids and canthin alkaloids. Bioorg. Med. Chem., 2004, 12(18), 4963-8.
    • (2004) Bioorg. Med. Chem. , vol.12 , Issue.18 , pp. 4963-4968
    • Murakami, C.1    Fukamiya, N.2    Tamura, S.3    Okano, M.4    Bastow, K.F.5    Tokuda, H.6    Mukainaka, T.7    Nishino, H.8    Lee, K.H.9
  • 40
    • 0347761416 scopus 로고    scopus 로고
    • Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia
    • Kuo, P. C.; Damu, A. G.; Lee, K. H.; Wu, T. S. Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia. Bioorg. Med. Chem., 2004, 12(3), 537-44.
    • (2004) Bioorg. Med. Chem. , vol.12 , Issue.3 , pp. 537-544
    • Kuo, P.C.1    Damu, A.G.2    Lee, K.H.3    Wu, T.S.4
  • 41
    • 0022588168 scopus 로고
    • Plants as sources of antimalarial drugs. Part 31 eurycoma longifolia
    • Chan, K. L.; O'Neill M, J.; Phillipson, J. D.; Warhurst, D. C. Plants as Sources of Antimalarial Drugs. Part 31 Eurycoma longifolia. Planta Med., 1986, 52(2), 105-7.
    • (1986) Planta Med. , vol.52 , Issue.2 , pp. 105-107
    • Chan, K.L.1    O'Neill M, J.2    Phillipson, J.D.3    Warhurst, D.C.4
  • 43
    • 12744274771 scopus 로고    scopus 로고
    • Quassinoids can induce mitochondrial membrane depolarisation and caspase 3 activation in human cells
    • Rosati, A.; Quaranta, E.; Ammirante, M.; Turco, M. C.; Leone, A.; De Feo, V. Quassinoids can induce mitochondrial membrane depolarisation and caspase 3 activation in human cells. Cell Death Differ., 2004, 11 Suppl 2, S216-8.
    • (2004) Cell Death Differ. , vol.11 , Issue.2 SUPPL.
    • Rosati, A.1    Quaranta, E.2    Ammirante, M.3    Turco, M.C.4    Leone, A.5    De Feo, V.6
  • 45
    • 65449183737 scopus 로고    scopus 로고
    • A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anti-cancer agent
    • Lavhale, M. S.; Kumar, S.; Mishra, S. H.; Sitasawad, S. L. A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anti-cancer agent. PLoS One, 2009, 4(4), e5365.
    • (2009) PLoS One , vol.4 , Issue.4
    • Lavhale, M.S.1    Kumar, S.2    Mishra, S.H.3    Sitasawad, S.L.4
  • 46
    • 0037467088 scopus 로고    scopus 로고
    • Isolation of phytotoxic compounds from tree-of-heaven (Ailanthus altissima swingle)
    • De Feo, V.; De Martino, L.; Quaranta, E.; Pizza, C. Isolation of phytotoxic compounds from tree-of-heaven (Ailanthus altissima swingle). J. Agric. Food Chem., 2003, 51(5), 1177-80.
    • (2003) J. Agric. Food Chem. , vol.51 , Issue.5 , pp. 1177-1180
    • De Feo, V.1    De Martino, L.2    Quaranta, E.3    Pizza, C.4
  • 47
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogenactivated protein kinase cascade for the treatment of cancer
    • Roberts, P. J.; Der, C. J. Targeting the Raf-MEK-ERK mitogenactivated protein kinase cascade for the treatment of cancer. Oncogene, 2007, 26(22), 3291-310.
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 48
    • 3843052715 scopus 로고    scopus 로고
    • HIF-1: A target for cancer, ischemia and inflammation-too good to be true?
    • Melillo, G. HIF-1: A target for cancer, ischemia and inflammation-too good to be true? Cell Cycle, 2004, 3(2), 154-5.
    • (2004) Cell Cycle , vol.3 , Issue.2 , pp. 154-155
    • Melillo, G.1
  • 50
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L. Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer, 2003, 3(10), 721-32.
    • (2003) Nat. Rev. Cancer , vol.3 , Issue.10 , pp. 721-732
    • Semenza, G.L.1
  • 52
    • 0027138356 scopus 로고
    • The role of p21ras in receptor tyrosine kinase signaling
    • Medema, R. H.; Bos, J. L. The role of p21ras in receptor tyrosine kinase signaling. Crit. Rev. Oncog., 1993, 4(6), 615-61.
    • (1993) Crit. Rev. Oncog. , vol.4 , Issue.6 , pp. 615-661
    • Medema, R.H.1    Bos, J.L.2
  • 53
    • 2342489456 scopus 로고    scopus 로고
    • EIF-4E expression and its role in malignancies and metastases
    • De Benedetti, A.; Graff, J. R. eIF-4E expression and its role in malignancies and metastases. Oncogene, 2004, 23(18), 3189-99.
    • (2004) Oncogene , vol.23 , Issue.18 , pp. 3189-3199
    • De Benedetti, A.1    Graff, J.R.2
  • 54
    • 85047696004 scopus 로고    scopus 로고
    • Translation initiation and its deregulation during tumorigenesis
    • Watkins, S. J.; Norbury, C. J. Translation initiation and its deregulation during tumorigenesis. Br. J. Cancer., 2002, 86(7), 1023-7.
    • (2002) Br. J. Cancer. , vol.86 , Issue.7 , pp. 1023-1027
    • Watkins, S.J.1    Norbury, C.J.2
  • 55
    • 38849180436 scopus 로고    scopus 로고
    • Targeting the eukaryotic translation initiation factor 4E for cancer therapy
    • Graff, J. R.; Konicek, B. W.; Carter, J. H.; Marcusson, E. G. Targeting the eukaryotic translation initiation factor 4E for cancer therapy. Cancer Res., 2008, 68(3), 631-4.
    • (2008) Cancer Res. , vol.68 , Issue.3 , pp. 631-634
    • Graff, J.R.1    Konicek, B.W.2    Carter, J.H.3    Marcusson, E.G.4
  • 56
    • 77955014467 scopus 로고    scopus 로고
    • Natural products as chemical probes
    • Carlson, E. E. Natural products as chemical probes. ACS Chem. Biol., 2010, 5(7), 639-53.
    • (2010) ACS Chem. Biol. , vol.5 , Issue.7 , pp. 639-653
    • Carlson, E.E.1
  • 57
    • 0020327082 scopus 로고
    • Antitumor agents XLV: Bisbrusatolyl and brusatolyl esters and related compounds as novel potent antileukemic agents
    • Lee, K. H.; Okano, M.; Hall, I. H.; Brent, D. A.; Soltmann, B. Antitumor agents XLV: Bisbrusatolyl and brusatolyl esters and related compounds as novel potent antileukemic agents. J. Pharm. Sci., 1982, 71(3), 338-45.
    • (1982) J. Pharm. Sci. , vol.71 , Issue.3 , pp. 338-345
    • Lee, K.H.1    Okano, M.2    Hall, I.H.3    Brent, D.A.4    Soltmann, B.5
  • 61
    • 0025871006 scopus 로고
    • Immunohistochemical analysis of N-myc protein expression in neuroblastoma: Correlation with prognosis of patients
    • Hiyama, E.; Hiyama, K.; Yokoyama, T.; Ishii, T. Immunohistochemical analysis of N-myc protein expression in neuroblastoma: Correlation with prognosis of patients. J. Pediatr. Surg., 1991, 26(7), 838-43.
    • (1991) J. Pediatr. Surg. , vol.26 , Issue.7 , pp. 838-843
    • Hiyama, E.1    Hiyama, K.2    Yokoyama, T.3    Ishii, T.4
  • 62
    • 59049091416 scopus 로고    scopus 로고
    • Low-level copy gain versus amplification of myc oncogenes in medulloblastoma: Utility in predicting prognosis and survival. Laboratory investigation
    • Takei, H.; Nguyen, Y.; Mehta, V.; Chintagumpala, M.; Dauser, R. C.; Adesina, A. M. Low-level copy gain versus amplification of myc oncogenes in medulloblastoma: Utility in predicting prognosis and survival. Laboratory investigation. J. Neurosurg. Pediatr., 2009, 3(1), 61-5.
    • (2009) J. Neurosurg. Pediatr. , vol.3 , Issue.1 , pp. 61-65
    • Takei, H.1    Nguyen, Y.2    Mehta, V.3    Chintagumpala, M.4    Dauser, R.C.5    Adesina, A.M.6
  • 64
    • 0033551387 scopus 로고    scopus 로고
    • Mechanisms of apoptosis by c-Myc
    • Prendergast, G. C. Mechanisms of apoptosis by c-Myc. Oncogene, 1999, 18(19), 2967-87.
    • (1999) Oncogene , vol.18 , Issue.19 , pp. 2967-2987
    • Prendergast, G.C.1
  • 65
    • 0033611644 scopus 로고    scopus 로고
    • Control of cell proliferation by Myc family genes
    • Eilers, M. Control of cell proliferation by Myc family genes. Mol. Cells, 1999, 9(1), 1-6.
    • (1999) Mol. Cells , vol.9 , Issue.1 , pp. 1-6
    • Eilers, M.1
  • 66
    • 37549032776 scopus 로고    scopus 로고
    • The interplay between MYC and HIF in cancer
    • Dang, C. V.; Kim, J. W.; Gao, P.; Yustein, J. The interplay between MYC and HIF in cancer. Nat. Rev. Cancer, 2008, 8(1), 51-6.
    • (2008) Nat. Rev. Cancer , vol.8 , Issue.1 , pp. 51-56
    • Dang, C.V.1    Kim, J.W.2    Gao, P.3    Yustein, J.4
  • 67
    • 0842309106 scopus 로고    scopus 로고
    • MYCN in neuronal tumours
    • Schwab, M. MYCN in neuronal tumours. Cancer Lett., 2004, 204(2), 179-87.
    • (2004) Cancer Lett. , vol.204 , Issue.2 , pp. 179-187
    • Schwab, M.1
  • 70
    • 0038107350 scopus 로고    scopus 로고
    • Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations
    • Karlsson, A.; Giuriato, S.; Tang, F.; Fung-Weier, J.; Levan, G.; Felsher, D. W. Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations. Blood, 2003, 101(7), 2797-803.
    • (2003) Blood , vol.101 , Issue.7 , pp. 2797-2803
    • Karlsson, A.1    Giuriato, S.2    Tang, F.3    Fung-Weier, J.4    Levan, G.5    Felsher, D.W.6
  • 72
    • 69049087664 scopus 로고    scopus 로고
    • Cellular signaling perturbation by natural products
    • Sarkar, F. H.; Li, Y.; Wang, Z.; Kong, D. Cellular signaling perturbation by natural products. Cell. Signal., 2009, 21(11), 1541-7.
    • (2009) Cell. Signal. , vol.21 , Issue.11 , pp. 1541-1547
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.