Cancer chemopreventive effect of quassinoid derivatives. Introduction of side chain to shinjulactone C for enhancement of inhibitory effect on Epstein-Barr virus activation

Cancer Letters

Volumn 185, Issue 1, 2002, Pages 47-51

  Tamura, Sadaaki ^a   Fukamiya, Narihiko ^a   Okano, Masayoshi ^a   Tokuda, Harukuni ^b   Aoi, Wataru ^b   Mukainaka, Teruo ^b   Nishino, Hoyoku ^b   Tagahara, Kiyoshi ^c   Koike, Kazuo ^d  

^a HIROSHIMA UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^d TOHO UNIVERSITY   (Japan)

Author keywords

Conversion of quassinoids; Epstein Barr virus early antigen activation; Inhibitory effect; Shinjulactone C

Indexed keywords

3',3' DIMETHYLSUCCINATE; EARLY ANTIGEN; GLUTARIC ACID DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; QUASSINOID DERIVATIVE; SHINJULACTONE C; SUCCINIC ACID; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; EPSTEIN BARR VIRUS EARLY ANTIGEN; EPSTEIN-BARR VIRUS EARLY ANTIGEN; LACTONE; VIRUS ANTIGEN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PREVENTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RAJI CELL; STRUCTURE ACTIVITY RELATION; VIRUS ACTIVATION; BARK; CELL CULTURE; CHEMISTRY; CHEMOPROPHYLAXIS; DOSE RESPONSE; DRUG EFFECT; IC 50; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; VIRUS INFECTION;

ANTIGENS, VIRAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHEMOPREVENTION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPSTEIN-BARR VIRUS INFECTIONS; HERPESVIRUS 4, HUMAN; HUMAN; INHIBITORY CONCENTRATION 50; LACTONES; PLANT BARK; QUASSINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED; VIRUS ACTIVATION; HUMANS;

HUMAN HERPESVIRUS 4;

EID: 0037044569     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00302-6     Document Type: Article

References (13)

1. Studies on inhibitors of skin-tumor promotion. V. Inhibitory effects of flavonoids on Epstein-Barr virus activation II
2. Studies on inhibitors of skin tumor promotion. VII. Inhibitory effects of steroids on Epstein-Barr virus activation
3. Studies on inhibitors of skin-tumor promotion. Inhibitory effects of triterpenes from Cochlospermum tinctrium on Epstein-Barr virus activation
4. Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate and teleocidin B induced Epstein-Barr Virus by Saponin and its related compounds
5. Studies on inhibitors of skin-tumor promotion. VI. Inhibitory effects of quinones on Epstein-Barr virus activation
6. Inhibitory effects of quassinoids on Epstein-Barr virus activation
7. Quassinoids as inhibitors of Epstein-Barr virus early antigen activation
8. Three new quassinoid derivatives and related compounds as antitumor promoters from Brucea javanica
9. Anti-HIV activity of quassinoids
10. Conversion of quassinoids for enhancement of inhibitory effects against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol
11. A short-term in vitro assay for promoter substances using human lymphoblastoid cells latently infected with Epstein-Barr virus
12. Immunofluorescence in cells derived from Burkitt's lymphoma
13. Search for possible antitumor promoters by inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation; Ursolic acid and oleanolic acid from an anti-inflammatory Chinese medicinal plant, Glechoma hederaceae L