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Volumn 1372, Issue , 2011, Pages 133-144

Linking hypoxic and oxidative insults to cell death mechanisms in models of ALS

Author keywords

Aif; ALS; amyotrophic lateral sclerosis; apoptosis inducing factor; chronic sustained hypoxic conditions; GSH; heme oxygenases 1; Hif 1 ; HO 1; hypoxia inducing factor 1 ; MN; motor neuron; PNC; primary neuronal cell of mouse cortex; reactive oxygen species; SOD; UCP4; uncoupling protein 4

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; COBALT CHLORIDE; CYTOCHROME C; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN UCP 4; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN;

EID: 79151482596     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.11.056     Document Type: Article
Times cited : (31)

References (50)
  • 1
    • 0034680825 scopus 로고    scopus 로고
    • The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia
    • F.H. Agani, P. Pichiule, J.C. Chavez, and J.C. LaManna The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia J. Biol. Chem. 275 2000 35863 35867
    • (2000) J. Biol. Chem. , vol.275 , pp. 35863-35867
    • Agani, F.H.1    Pichiule, P.2    Chavez, J.C.3    Lamanna, J.C.4
  • 3
    • 33749056809 scopus 로고    scopus 로고
    • ALS: A disease of motor neurons and their nonneuronal neighbors
    • S. Vande Boillée, C. Velde, and D.W. Cleveland ALS: a disease of motor neurons and their nonneuronal neighbors Neuron 52 2006 39 59
    • (2006) Neuron , vol.52 , pp. 39-59
    • Vande, B.S.1    Velde, C.2    Cleveland, D.W.3
  • 4
    • 0031868461 scopus 로고    scopus 로고
    • Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis
    • M.B. Bogdanov, L.E. Ramos, Z. Xu, and M.F. Beal Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis J. Neurochem. 71 1998 1321 1324
    • (1998) J. Neurochem. , vol.71 , pp. 1321-1324
    • Bogdanov, M.B.1    Ramos, L.E.2    Xu, Z.3    Beal, M.F.4
  • 5
    • 12244268624 scopus 로고    scopus 로고
    • Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death?
    • C. Candé, F. Cecconi, P. Dessen, and G. Kroemer Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J. Cell Sci. 115 2002 4727 4734
    • (2002) J. Cell Sci. , vol.115 , pp. 4727-4734
    • Candé, C.1    Cecconi, F.2    Dessen, P.3    Kroemer, G.4
  • 7
    • 0036138596 scopus 로고    scopus 로고
    • Mitochondrial ROS metabolism: Modulation by uncoupling proteins
    • L. Casteilla, M. Rigoulet, and L. Pénicaud Mitochondrial ROS metabolism: modulation by uncoupling proteins IUBMB Life 52 2001 181 188
    • (2001) IUBMB Life , vol.52 , pp. 181-188
    • Casteilla, L.1    Rigoulet, M.2    Pénicaud, L.3
  • 9
    • 33845985635 scopus 로고    scopus 로고
    • Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells
    • S.L. Chan, D. Liu, G.A. Kyriazis, P. Bagsiyao, X. Ouyang, and M.P. Mattson Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells J. Biol. Chem. 281 2006 37391 37403
    • (2006) J. Biol. Chem. , vol.281 , pp. 37391-37403
    • Chan, S.L.1    Liu, D.2    Kyriazis, G.A.3    Bagsiyao, P.4    Ouyang, X.5    Mattson, M.P.6
  • 11
    • 33845773367 scopus 로고    scopus 로고
    • Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo
    • L. Chi, Y. Ke, C. Luo, D. Gozal, and R. Liu Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo Neuroscience 144 2007 991 1003
    • (2007) Neuroscience , vol.144 , pp. 991-1003
    • Chi, L.1    Ke, Y.2    Luo, C.3    Gozal, D.4    Liu, R.5
  • 12
    • 71649085107 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: A new hope to counteract neurodegeneration?
    • S.C. Correia, and P.I. Moreira Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration? J. Neurochem. 112 2010 1 12
    • (2010) J. Neurochem. , vol.112 , pp. 1-12
    • Correia, S.C.1    Moreira, P.I.2
  • 13
    • 33746238205 scopus 로고    scopus 로고
    • Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease
    • S.M. de la Monte, and J.R. Wands Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease J. Alzheimers Dis. 9 2006 167 181
    • (2006) J. Alzheimers Dis. , vol.9 , pp. 167-181
    • De La Monte, S.M.1    Wands, J.R.2
  • 14
    • 0032051634 scopus 로고    scopus 로고
    • Heme oxygenase in the experimental ALS mouse
    • B.E. Dwyer, S.Y. Lu, and R.N. Nishimura Heme oxygenase in the experimental ALS mouse Exp. Neurol. 150 1998 206 212
    • (1998) Exp. Neurol. , vol.150 , pp. 206-212
    • Dwyer, B.E.1    Lu, S.Y.2    Nishimura, R.N.3
  • 15
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • R.M. Friedlander Apoptosis and caspases in neurodegenerative diseases N. Engl. J. Med. 348 2003 1365 1375
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 16
    • 0024273450 scopus 로고    scopus 로고
    • Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein
    • M.A. Goldberg, S.P. Dunning, and H.F. Bunn Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein Science 242 1998 1412 1415
    • (1998) Science , vol.242 , pp. 1412-1415
    • Goldberg, M.A.1    Dunning, S.P.2    Bunn, H.F.3
  • 17
    • 0035437866 scopus 로고    scopus 로고
    • Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis
    • C. Guégan, M. Vila, G. Rosoklija, A.P. Hays, and S. Przedborski Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis J. Neurosci. 21 2001 6569 6576
    • (2001) J. Neurosci. , vol.21 , pp. 6569-6576
    • Guégan, C.1    Vila, M.2    Rosoklija, G.3    Hays, A.P.4    Przedborski, S.5
  • 19
    • 0032127330 scopus 로고    scopus 로고
    • Relationship of oxygen radical- induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS
    • E.D. Hall, P.K. Andrus, J.A. Oostveen, T.J. Fleck, and M.E. Gurney Relationship of oxygen radical- induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS J. Neurosci. Res. 53 1998 66 77
    • (1998) J. Neurosci. Res. , vol.53 , pp. 66-77
    • Hall, E.D.1    Andrus, P.K.2    Oostveen, J.A.3    Fleck, T.J.4    Gurney, M.E.5
  • 20
    • 0033566792 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53
    • M.W. Halterman, C.C. Miller, and H.J. Federoff Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53 J. Neurosci. 19 1999 6818 6824
    • (1999) J. Neurosci. , vol.19 , pp. 6818-6824
    • Halterman, M.W.1    Miller, C.C.2    Federoff, H.J.3
  • 21
    • 33748581394 scopus 로고    scopus 로고
    • Apomorphine protects against 6- hydroxydopamine-induced neuronal cell death through activation of the Nrf2-ARE pathway
    • H. Hara, M. Ohta, and T. Adachi Apomorphine protects against 6- hydroxydopamine-induced neuronal cell death through activation of the Nrf2-ARE pathway J. Neurosci. Res. 84 2006 860 866
    • (2006) J. Neurosci. Res. , vol.84 , pp. 860-866
    • Hara, H.1    Ohta, M.2    Adachi, T.3
  • 22
    • 2142694340 scopus 로고    scopus 로고
    • Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling
    • S.J. Hong, T.M. Dawson, and V.L. Dawson Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling Trends Pharmacol. Sci. 25 2004 259 264
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 259-264
    • Hong, S.J.1    Dawson, T.M.2    Dawson, V.L.3
  • 24
    • 0035947221 scopus 로고    scopus 로고
    • Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model
    • C. Jung, Y. Rong, S. Doctrow, M. Baudry, B. Malfroy, and Z. Xu Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model Neurosci. Lett. 304 2001 157 160
    • (2001) Neurosci. Lett. , vol.304 , pp. 157-160
    • Jung, C.1    Rong, Y.2    Doctrow, S.3    Baudry, M.4    Malfroy, B.5    Xu, Z.6
  • 25
    • 0036959552 scopus 로고    scopus 로고
    • Possible signaling by glutathione and its novel analogue through potent stimulation of fontocortical G proteins in normal aging and in Alzheimer's disease
    • E. Karelson, R. Mahlapuu, M. Zilmer, U. Soomets, N. Bogdanovic, and U. Langel Possible signaling by glutathione and its novel analogue through potent stimulation of fontocortical G proteins in normal aging and in Alzheimer's disease Ann. NY Acad. Sci. 973 2002 537 540
    • (2002) Ann. NY Acad. Sci. , vol.973 , pp. 537-540
    • Karelson, E.1    Mahlapuu, R.2    Zilmer, M.3    Soomets, U.4    Bogdanovic, N.5    Langel, U.6
  • 26
    • 33645240078 scopus 로고    scopus 로고
    • Endothelin-2/vasoactive intestinal contractor: Regulation of expression via reactive oxygen species induced by CoCl2, and biological activities including neurite outgrowth in PC12 cells
    • E. Kotake-Nara, and K. Saida Endothelin-2/vasoactive intestinal contractor: regulation of expression via reactive oxygen species induced by CoCl2, and biological activities including neurite outgrowth in PC12 cells Sci. World J. 6 2006 176 186
    • (2006) Sci. World J. , vol.6 , pp. 176-186
    • Kotake-Nara, E.1    Saida, K.2
  • 27
    • 33845357105 scopus 로고    scopus 로고
    • Role of HIF-1 in iron regulation: Potential therapeutic strategy for neurodegenerative disorders
    • D.W. Lee, and J.K. Andersen Role of HIF-1 in iron regulation: potential therapeutic strategy for neurodegenerative disorders Curr. Mol. Med. 6 2006 883 893
    • (2006) Curr. Mol. Med. , vol.6 , pp. 883-893
    • Lee, D.W.1    Andersen, J.K.2
  • 28
    • 5044238503 scopus 로고    scopus 로고
    • Polychlorinated biphenyl mixture aroclor 1254- induced oxidative stress plays a role in dopaminergic cell injury
    • D.W. Lee, and L.A. Opanashuk Polychlorinated biphenyl mixture aroclor 1254- induced oxidative stress plays a role in dopaminergic cell injury Neurotoxicology 25 2004 925 939
    • (2004) Neurotoxicology , vol.25 , pp. 925-939
    • Lee, D.W.1    Opanashuk, L.A.2
  • 29
    • 0037451069 scopus 로고    scopus 로고
    • VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death
    • B. Li, W. Xu, C. Luo, D. Gozal, and R. Liu VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death Brain Res. Mol. Brain Res. 111 2003 155 164
    • (2003) Brain Res. Mol. Brain Res. , vol.111 , pp. 155-164
    • Li, B.1    Xu, W.2    Luo, C.3    Gozal, D.4    Liu, R.5
  • 31
    • 0031768025 scopus 로고    scopus 로고
    • Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • R. Liu, J.S. Althaus, B.R. Ellerbrock, D.A. Becker, and M.E. Gurney Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis Ann. Neurol. 44 1998 763 770
    • (1998) Ann. Neurol. , vol.44 , pp. 763-770
    • Liu, R.1    Althaus, J.S.2    Ellerbrock, B.R.3    Becker, D.A.4    Gurney, M.E.5
  • 32
    • 0036488219 scopus 로고    scopus 로고
    • Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival
    • R. Liu, B. Li, S.W. Flanagan, L.W. Oberley, D. Gozal, and M. Qiu Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival J. Neurochem. 80 2002 488 500
    • (2002) J. Neurochem. , vol.80 , pp. 488-500
    • Liu, R.1    Li, B.2    Flanagan, S.W.3    Oberley, L.W.4    Gozal, D.5    Qiu, M.6
  • 33
    • 0037468467 scopus 로고    scopus 로고
    • Oxidized glutathione stimulated the amyloid formation of alpha-synuclein
    • S.R. Paik, D. Lee, H.J. Cho, E.N. Lee, and C.S. Chang Oxidized glutathione stimulated the amyloid formation of alpha-synuclein FEBS Lett. 537 2003 63 67
    • (2003) FEBS Lett. , vol.537 , pp. 63-67
    • Paik, S.R.1    Lee, D.2    Cho, H.J.3    Lee, E.N.4    Chang, C.S.5
  • 34
    • 0035091326 scopus 로고    scopus 로고
    • Genetic and physiological analysis of the role of uncoupling proteins in human energy homeostasis
    • C. Pecqueur, E. Couplan, F. Bouillaud, and D. Ricquier Genetic and physiological analysis of the role of uncoupling proteins in human energy homeostasis J. Mol. Med. 79 2001 48 56
    • (2001) J. Mol. Med. , vol.79 , pp. 48-56
    • Pecqueur, C.1    Couplan, E.2    Bouillaud, F.3    Ricquier, D.4
  • 35
    • 0942287085 scopus 로고    scopus 로고
    • Programmed cell death in amyotrophic lateral sclerosis: A mechanism of pathogenic and therapeutic importance
    • S. Przedborski Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance Neurologist 10 2004 1 7
    • (2004) Neurologist , vol.10 , pp. 1-7
    • Przedborski, S.1
  • 36
    • 60849093466 scopus 로고    scopus 로고
    • Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
    • J.D. Rothstein Current hypotheses for the underlying biology of amyotrophic lateral sclerosis Ann. Neurol. 65 Suppl 1 2009 S3 S9
    • (2009) Ann. Neurol. , vol.65 , Issue.SUPPL. 1
    • Rothstein, J.D.1
  • 37
    • 0030809974 scopus 로고    scopus 로고
    • Subcellular distribution of glyceraldehyde-3-phosphate dehydrogenase in cerebellar granule cells undergoing cytosine arabinoside-induced apoptosis
    • P.A. Saunders, E. Chalecka-Franaszek, and D.M. Chuang Subcellular distribution of glyceraldehyde-3-phosphate dehydrogenase in cerebellar granule cells undergoing cytosine arabinoside-induced apoptosis J. Neurochem. 69 1997 1820 1828
    • (1997) J. Neurochem. , vol.69 , pp. 1820-1828
    • Saunders, P.A.1    Chalecka-Franaszek, E.2    Chuang, D.M.3
  • 38
    • 1842608814 scopus 로고    scopus 로고
    • Heme oxygenase-1: Transducer of pathological brain iron sequestration under oxidative stress
    • H.M. Schipper Heme oxygenase-1: transducer of pathological brain iron sequestration under oxidative stress Ann. NY Acad. Sci. 1012 2004 84 93
    • (2004) Ann. NY Acad. Sci. , vol.1012 , pp. 84-93
    • Schipper, H.M.1
  • 39
  • 40
    • 23144448320 scopus 로고    scopus 로고
    • Molecular and cellular pathways of neurodegeneration in motor neurone disease
    • P.J. Shaw Molecular and cellular pathways of neurodegeneration in motor neurone disease J. Neurol. Neurosurg. Psychiatry 76 2005 1046 1057
    • (2005) J. Neurol. Neurosurg. Psychiatry , vol.76 , pp. 1046-1057
    • Shaw, P.J.1
  • 42
    • 34547439281 scopus 로고    scopus 로고
    • Astroglia overexpressing heme oxygenase -1 predispose co-cultured PC12 cells to oxidative injury
    • L. Song, W. Song, and H.M. Schipper Astroglia overexpressing heme oxygenase -1 predispose co-cultured PC12 cells to oxidative injury J. Neurosci. Res. 85 2007 2186 2195
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2186-2195
    • Song, L.1    Song, W.2    Schipper, H.M.3
  • 43
    • 0025801631 scopus 로고
    • Heme oxygenase induction by CoCl2, co-protoporphyrin IX, phenylhydrazine, and diamide: Evidence for oxidative stress involvement
    • M.L. Tomaro, J. Frydman, and R.B. Frydman Heme oxygenase induction by CoCl2, co-protoporphyrin IX, phenylhydrazine, and diamide: evidence for oxidative stress involvement Arch. Biochem. Biophys. 286 1991 610 617
    • (1991) Arch. Biochem. Biophys. , vol.286 , pp. 610-617
    • Tomaro, M.L.1    Frydman, J.2    Frydman, R.B.3
  • 44
    • 0030910404 scopus 로고    scopus 로고
    • Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease
    • P.H. Tu, M.E. Gurney, J.P. Julien, V.M. Lee, and J.Q. Trojanowski Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease Lab. Invest. 76 1997 441 456
    • (1997) Lab. Invest. , vol.76 , pp. 441-456
    • Tu, P.H.1    Gurney, M.E.2    Julien, J.P.3    Lee, V.M.4    Trojanowski, J.Q.5
  • 45
    • 42249102078 scopus 로고    scopus 로고
    • Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
    • B.J. Turner, and K. Talbot Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS Prog. Neurobiol. 85 2008 94 134
    • (2008) Prog. Neurobiol. , vol.85 , pp. 94-134
    • Turner, B.J.1    Talbot, K.2
  • 46
    • 0033083082 scopus 로고    scopus 로고
    • Stereological methods for estimating the total number of neurons and synapses: Issues of precision and bias
    • M.J. West Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias Trends Neurosci. 22 1999 51 61
    • (1999) Trends Neurosci. , vol.22 , pp. 51-61
    • West, M.J.1
  • 47
    • 0026099960 scopus 로고
    • Motor neuron disease (amyotrophic lateral sclerosis)
    • D.B. Williams, and A.J. Windebank Motor neuron disease (amyotrophic lateral sclerosis) Mayo Clin. Proc. 66 1991 54 82
    • (1991) Mayo Clin. Proc. , vol.66 , pp. 54-82
    • Williams, D.B.1    Windebank, A.J.2
  • 48
    • 9344262366 scopus 로고    scopus 로고
    • Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling
    • L. Xi, M. Taher, C. Yin, F. Salloum, and R.C. Kukreja Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling Am. J. Physiol. Heart Circ. Physiol. 287 2004 H2369 H2375
    • (2004) Am. J. Physiol. Heart Circ. Physiol. , vol.287
    • Xi, L.1    Taher, M.2    Yin, C.3    Salloum, F.4    Kukreja, R.C.5
  • 49
    • 2942668297 scopus 로고    scopus 로고
    • Increased oxidative stress is associated with chronic intermittent hypoxia-mediated brain cortical neuronal cell apoptosis in a mouse model of sleep apnea
    • W. Xu, L. Chi, B.W. Row, R. Xu, Y. Ke, B. Xu, C. Luo, L. Kheirandish, D. Gozal, and R. Liu Increased oxidative stress is associated with chronic intermittent hypoxia-mediated brain cortical neuronal cell apoptosis in a mouse model of sleep apnea Neuroscience 126 2004 313 323
    • (2004) Neuroscience , vol.126 , pp. 313-323
    • Xu, W.1    Chi, L.2    Row, B.W.3    Xu, R.4    Ke, Y.5    Xu, B.6    Luo, C.7    Kheirandish, L.8    Gozal, D.9    Liu, R.10
  • 50
    • 0035877175 scopus 로고    scopus 로고
    • Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation
    • W. Zou, M. Yan, W. Xu, H. Huo, L. Sun, Z. Zheng, and X. Liu Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation J. Neurosci. Res. 64 2001 646 653
    • (2001) J. Neurosci. Res. , vol.64 , pp. 646-653
    • Zou, W.1    Yan, M.2    Xu, W.3    Huo, H.4    Sun, L.5    Zheng, Z.6    Liu, X.7


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