Apomorphine protects against 6-hydroxydopamine-induced neuronal cell death through activation of the Nrf2-ARE pathway

Journal of Neuroscience Research

Volumn 84, Issue 4, 2006, Pages 860-866

  Hara, Hirokazu ^a   Ohta, Mitsuhiro ^b   Adachi, Tetsuo ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Neuroprotection; Oxidative stress; Parkinson's disease; SH SY5Y; Transcription factor

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ACETYLCYSTEINE; APOMORPHINE; HEME OXYGENASE 1; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SULPIRIDE; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG INHIBITION; DRUG MECHANISM; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ADRENERGIC AGENTS; APOMORPHINE; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME ACTIVATION; FLOW CYTOMETRY; HEME OXYGENASE-1; HUMANS; NEUROBLASTOMA; NF-E2-RELATED FACTOR 2; OXIDOPAMINE; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 33748581394     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20974     Document Type: Article

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