Stereology: A Practical Primer for Neuropathology

Journal of Neuropathology and Experimental Neurology

Volumn 57, Issue 4, 1998, Pages 305-310

  Hyman, Bradley T ^a   Gomez Isla, Teresa ^a   Irizarry, Michael C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DENSITY; DIAGNOSTIC VALUE; ENTORHINAL CORTEX; NEUROPATHOLOGY; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REVIEW; STEREOLOGY; THEORY;

EID: 0031920198     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199804000-00001     Document Type: Review

References (16)

1. West J, Coleman P. How to count. Neurobiol Aging 1996;17:503
2. Saper CB. Any way you cut it: A new journal policy for the use of unbiased counting methods. J Comp Neurol 1996;364:5
3. Sterio D. The unbiased estimation of number and size of arbitrary particles using the disector. J Microsc 1984;134:127-36
4. West M, Gundersen H. Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 1990;296:1-22
5. Coggeshall RE, Lekan HA. Methods for determining numbers of cells and synapses: A case for more uniform standards of review. J Comp Neurol 1996;364:6-15
6. Gomez-Isla T, Price J, McKeel D, Morris J, Greenberg S, Petersen R, Parisi J, Growdon JH, Hyman B. Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. J Neurosci 1996;16:4491-4500
7. West M. New stereological methods for counting neurons. Neurobiol Aging 1993;14:275-85
8. Gomez-Isla T, Hollister R, West H, Mui S, Growdon J, Petersen R, Parisi J, Hyman B. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann Neurol 1997;41:17-24
9. Regeur L, Jensen G, Pakkenberg H, et al. No global neocortical nerve cell loss in brains from patients with senile dementia of Alzheimer's type. Neurobiol Aging 1994;15:347-52
10. Hyman B, Gomez-Isla T. Alzheimer's disease is a laminar, regional, and neural system specific disease. Neurobiol Aging 1994;15:353-54
11. Terry RD. The pathology of Alzheimer's disease: Numbers count. Ann Neurol 1997;41:7
12. Everall I, DeTeresa R, Terry R, Masliah E. Comparison of two quantitative methods for the evaluation of neuronal number in the frontal cortex in Alzheimer disease. J Neuropathol Exp Neurol 1997;56:1202-6
13. Srivastava R, Brouillet E, Beal M, Storey E, Hyman BT. Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: A sterological estimate of neuronal loss. Neurobiol Aging 1993;14:295-301
14. Golden J, Hyman BT. Neocortical development in trisomy 21. J Neuropath Exp Neurol 1993;52:285
15. Irizarry M, McNamara M, Fedorchak K, Hsiao K, Hyman B. APPsw transgenic mice develop age-related A-beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J Neuropathol Exp Neurol 1997;56:965-73
16. Irizarry M, Soriano F, McNamara M, Page K, Schenk D, Games D, Hyman B. A-beta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J Neurosci 1997;17:7053-59