Effects of esomeprazole on healing of nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers in the presence of a continued NSAID treatment: Characterization of molecular mechanisms

Pharmacological Research

Volumn 63, Issue 1, 2011, Pages 59-67

  Fornai, Matteo ^a   Colucci, Rocchina ^a   Antonioli, Luca ^a   Awwad, Oriana ^a   Ugolini, Clara ^a   Tuccori, Marco ^a   Fulceri, Federica ^a   Natale, Gianfranco ^a   Basolo, Fulvio ^a   Blandizzi, Corrado ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Apoptosis; Esomeprazole; Gastric ulcer healing; NSAIDs; Oxidative damage

Indexed keywords

BRISTOL; CASPASE 3; CYCLINE; CYCLOOXYGENASE 2; ESOMEPRAZOLE; FAMOTIDINE; INDOMETACIN; KI 67 ANTIGEN; LANSOPRAZOLE; MALONALDEHYDE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; GASTROINTESTINAL TOXICITY; MALE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STOMACH INJURY; STOMACH MUCOSA; STOMACH ULCER; TISSUE LEVEL; TREATMENT DURATION; ULCER HEALING;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL PROLIFERATION; CYCLOOXYGENASE 2; DINOPROSTONE; DISEASE MODELS, ANIMAL; FAMOTIDINE; GASTRIC ACID; GASTRIC MUCOSA; HISTAMINE H2 ANTAGONISTS; IMMUNOHISTOCHEMISTRY; INDOMETHACIN; KI-67 ANTIGEN; MALE; MALONDIALDEHYDE; OMEPRAZOLE; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTON PUMP INHIBITORS; RATS; RATS, WISTAR; STOMACH ULCER; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 79151479663     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2010.10.013     Document Type: Article

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