Angiogenic and cell proliferating action of the natural diarylnonanoids, malabaricone B and malabaricone C during healing of indomethacin-induced gastric ulceration

Pharmaceutical Research

Volumn 25, Issue 7, 2008, Pages 1601-1609

  Banerjee, Debashish ^a   Maity, Biswanath ^a   Bandivdeker, Atmaram H ^b   Bandyopadhyay, Sandip K ^a   Chattopadhyay, Subrata ^c  

^a Dr BC Roy Post Graduate Institute of Basic Medical Sciences   (India)

^b Institute for Research in Reproduction India   (India)

^c BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Angiogenesis; EGF; Endostatin; Gastrointestinal toxicology; Malabaricone; VEGF

Indexed keywords

ENDOSTATIN; EPIDERMAL GROWTH FACTOR; INDOMETACIN; MALABARICONE B; MALABARICONE C; MISOPROSTOL; OMEPRAZOLE; PHENOL DERIVATIVE; VASCULOTROPIN;

ACUTE TOXICITY; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; IMMUNOHISTOCHEMISTRY; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; STOMACH ULCER; TREATMENT DURATION; ULCER HEALING;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOSTATINS; EPIDERMAL GROWTH FACTOR; GASTRIC MUCOSA; GRANULATION TISSUE; INDOMETHACIN; MALE; MICE; MISOPROSTOL; NEOVASCULARIZATION, PHYSIOLOGIC; OMEPRAZOLE; REGIONAL BLOOD FLOW; RESORCINOLS; STOMACH ULCER; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VON WILLEBRAND FACTOR;

EID: 44749088084     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-007-9512-0     Document Type: Article

References (32)

1. C. Hawkins, and G. W. Hanks. The gastroduodenal toxicity of nonsteroidal anti-inflammatory drugs. A review of the literature. J. Pain Symp. Manag 20:140-151 (2000).
2. M. J. Lancaster-Smith, M. R. Jaderberg, and D. A. Jackson. Ranitidine in the treatment of non-steroidal anti-inflammatory drug associated gastric and duodenal ulcers. Gut 32:252-256 (1991).
3. F. Halter, A. Schamassman, B. M. Peskar, and A. S. Tarnawski. Cyclooxygenase-2 implications on maintenance of gastric mucosal integrity and ulcer healing: controversies and perspectives. Gut 49:443-453 (2001).
4. H. Hirose, K. Takeuchi, and S. Okabe. Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats. Gastroenterol 100:1259-1265 (1991).
5. A. Tarnawski, T. G. Douglass, J. Stachura, and W. J. Krause. Quality of gastric ulcer healing: histological ultrastructural assessment. Aliment Pharmacol. Therap 5(Suppl 1):79-90 (1991).
6. M. H. McGrath, and J. M. I. Emery. The effect of inhibition of angiogenesis in granulation tissue on wound healing and the fibroblast. Ann. Plast Surg 15:106-119 (1985).
7. B. S. Patro, A. K. Bauri, S. Mishra, and S. Chattopadhyay. Antioxidant activity of Myristica malabarica extracts and its constituents. J. Agric. Food Chem 53:6912-6918 (2005).
8. K. Biswas, U. Bandyopadhyay, I. Chattopadhyay, A. Varadaraj, E. Ali, and R. K. Banerjee. A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical. J. Biol. Chem 278:10993-11001 (2003).
9. D. Dokmeci, M. Akpolat, N. Aydogu, L. Doganay, and F. N. Turan. L-Carnitine inhibits ethanol-induced gastric mucosal injury in rats. Pharmacol. Rep 57:481-488 (2005).
10. D. Banerjee, B. Maity, S. K. Bandyopadhyay, A. K. Bauri, and S. Chattopadhyay. Gastroprotective properties of Myristica malabarica against indomethacin-induced stomach ulceration: a mechanistic exploration. J. Pharm. Phamacol. 59:1555-1565 (2007).
11. K. Yokoi, P. H. Thaker, S. Y. Robert, R. Rebhun, D. H. Nam, J. He, S. J. Kim, J. L. Abbruzzese, S. R. Hamilton, and I. J. Fidler. Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE 788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. Cancer Res 65:3716-3725 (2005).
12. N. Weidner, J. P. Semple, W. R. Welch, and J. Folkman. Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. New Engl. J. Med 324:1-8 (1991).
13. A. Schmassmann. Mechanisms of ulcer healing and effects of nonsteroidal anti-inflammatory drugs. Am. J. Med 104:43S-51S (1998).
14. M. K. Jones, H. Wang, B. M. Peskar, E. Levin, R. M. Itani, I. J. Sarfeh, and A. S. Tarnawski. Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. Nat. Med 5:1418-1423 (1999).
15. J. L. Wallace, and D. N. Granger. The cellular and molecular basis of gastric mucosal defense. FASEB J 10:731-740 (1996).
16. R. Lad, and D. Armstrong. Management of nonsteroidal anti-inflammatory drug-induced gastroduodenal disease by acid suppression. Can. J. Gastroenterol 13:135-142 (1999).
17. S. G. Chiverton, D. W. Burget, B. J. Salena, and R. H. Hunt. Does misoprostol given as a single large dose improve its antisecretory effect? Aliment Pharmacol. Ther 3:403-407 (1989).
18. W. M. Hui, B. W. Chen, C. H. Cho, C. T. Luk, and S. K. Lam. Role of gastric mucosal blood flow in cytoprotection. Digestion 48:113-120 (1991).
19. R. J. Coffey, M. Romano, and J. Goldenring. Roles for transforming growth factor-alpha in the stomach. J. Clin. Gastroenterol 2(Suppl 1):S36-S39 (1995).
20. L. R. Johnson, and S. A. McCormack. Regulation of gastrointestinal mucosal growth. In L. R. Johnson (ed.), Physiology of the Gastrointestinal Tract, (3rd edn), Raven, New York, 1994, pp. 611-641.
21. R. Pai, and A. S. Tarnawski. Signal transduction cascades triggered by EGF Receptor activation: relevance to gastric injury repair and ulcer healing. Dig. Dis. Sci 43(9 Suppl):14S-22S (1998).
22. A. Calabro, B. Orsini, A. Brocchi, M. Falchini, P. Fedi, and C. Surrenti. Gastric juice immunoreactive epidermal growth factor levels in patients with peptic ulcer disease. Am. J. Gastroenterol 85:404-407 (1990).
23. N. A. Wright, C. Pike, and G. Elia. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in the human gastrointestinal stem cells. Nature 343:82-85 (1990).
24. S. Szabo, and A. Vincze. Growth factors in ulcer healing: lessons from recent studies. J. Physiol. (London) 94:77-81 (2000).
25. J. Jin, and S. P. Kunapuli. Co-activation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation. Proc. Natl. Acad. Sci. USA 95:8070-8074 (1998).
26. M. S. O'Reilly, T. Boehm, Y. Shing, N. Fukai, G. Vasios, W. S. Lane, E. Flynn, J. R. Birkhead, B. R. Olsen, and J. Folkman. Endostatin: An endogenous. inhibitor of angiogenesis and tumour growth. Cell 88:277-285 (1997).
27. N. Yamaguchi, B. Anand-Apte, M. Lee, T. Sasaki, N. Fukai, R. Shapiro, I. Que, C. Lowik, R. Timpl, and B. R. Olsen. Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J 18:4414-4423 (1999).
28. E. Dejana, M. G. Lampugnani, M. Giorgi, et al. Von Willebrand factor promotes endothelial cell adhesion via an Arg-Gly-Asp-dependent mechanism. J. Cell Biol 109:367-375 (1989).
29. C. Wheeler-Jones, R. Abu-Ghazaleh, R. Cospedal, R. A. Houliston, J. Martin, and I. Zachary. Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 icn endothelial cells via p42/p44 mitogen activated protein kinases. FEBS Left 420:28-32 (1997).
30. T. Tsuchida, Y. Tsukamoto, K. Segawa, H. Goto, and S. Hase. Effects of cimetidine and omeprazole on angiogenesis in granulation tissue of acetic acid-induced gastric ulcers in rats. Digestion 47:8-14 (1990).
31. W. A. Hoogerwerf, and P. J. Pasricha. Agents used for control of gastric acidity and treatment of peptic ulcers and gastroesophageal reflux disease. In J. G. Hardmann, L. E. Limbird, L. S. Goodman, and A. G. Gilman (eds.), Goodman & Gilman's The Pharmacological Basis of Therapeutics, (10th ed), Mc Graw-Hill, New York, 2001, pp. 1005-1019.
32. A. Schmassmann, A. Tarnawski, B. M. Peskar, L. Varga, B. Flogerzi, and F. Halter. Influence of acid and angiogenesis on kinetics of gastric ulcer healing in rats: interaction with indomethacin. Am. J. Physiol. Gastrointest. Liver Physiol 268:G276-G285 (1995).