Effects of esomeprazole on glutathione levels and mitochondrial oxidative phosphorylation in the gastric mucosa of rats treated with indomethacin

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 378, Issue 4, 2008, Pages 421-429

  Pastoris, O ^a   Verri, M ^a   Boschi, F ^a   Kastsiuchenka, O ^b   Balestra, B ^a   Pace, F ^c   Tonini, M ^a   Natale, G ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Esomeprazole; Gastric mucosa; Nonsteroidal anti inflammatory drugs (NSAIDs); Oxidative injury

Indexed keywords

CYTOCHROME C OXIDASE; ESOMEPRAZOLE; GLUTATHIONE; INDOMETACIN; METHYLCELLULOSE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTON PUMP INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; MALE; MITOCHONDRIAL RESPIRATION; MORPHOMETRICS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; RAT; RESPIRATORY CHAIN; STOMACH MUCOSA; STOMACH MUCOSA LESION; STOMACH PROTECTION; STOMACH SECRETION; TISSUE LEVEL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; GASTRIC MUCOSA; GLUTATHIONE; GLUTATHIONE DISULFIDE; INDOMETHACIN; INTUBATION, GASTROINTESTINAL; MALE; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIA; NECROSIS; OMEPRAZOLE; OXIDATIVE PHOSPHORYLATION; RATS; RATS, WISTAR; SPECTROPHOTOMETRY; STOMACH DISEASES;

EID: 51749084633     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0314-7     Document Type: Article

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