Active immunization using a single dose immunotherapeutic abates established EAE via IL-10 and regulatory T cells

European Journal of Immunology

Volumn 41, Issue 2, 2011, Pages 313-323

  Rynda Apple, Agnieszka ^a   Huarte, Eduardo ^a   Maddaloni, Massimo ^a   Callis, Gayle ^a   Skyberg, Jerod A ^a   Pascual, David W ^a  

^a MONTANA STATE UNIVERSITY   (United States)

Author keywords

Autoimmunity; EAE; Mucosal immunity; Treg

Indexed keywords

CD39 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; HYBRID PROTEIN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 28; INTERLEUKIN 4; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN PSIGMA1; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ACTIVE IMMUNIZATION; ADOPTIVE TRANSFER; ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIGEN SPECIFICITY; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; FEMALE; IMMUNE RESPONSE; IMMUNITY; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SINGLE DRUG DOSE; TH2 CELL;

ADOPTIVE TRANSFER; ANIMALS; CAPSID PROTEINS; CELL COUNT; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GLYCOPROTEINS; HYPERSENSITIVITY, DELAYED; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; INTERLEUKIN-10; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELIN-ASSOCIATED GLYCOPROTEIN; PEPTIDE FRAGMENTS; SPINAL CORD; SPLEEN; T-LYMPHOCYTES, REGULATORY; TH2 CELLS; VACCINATION; VACCINES, SYNTHETIC;

EID: 78851472201     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201041104     Document Type: Article

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