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Volumn 54, Issue 5, 2011, Pages 911-925

Frontal affinity chromatography in characterizing immobilized receptors

Author keywords

Binding affinity; Biochromatography; Frontal affinity chromatography (FAC); On line screening; Receptor immobilization

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BUNGAROTOXIN RECEPTOR; CALCIUM CHANNEL L TYPE; CELL NUCLEUS RECEPTOR; CYTOSOL RECEPTOR; EPHRIN RECEPTOR B2; ESTROGEN RECEPTOR; ESTROGEN RELATED RECEPTOR ALPHA; G PROTEIN COUPLED RECEPTOR; HISTAMINE H1 RECEPTOR; IMMOBILIZED RECEPTOR; ION CHANNEL; KAPPA OPIATE RECEPTOR; LIGAND; MEMBRANE RECEPTOR; MU OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; PURINERGIC P2Y1 RECEPTOR; RECEPTOR; SILICON DIOXIDE; UNCLASSIFIED DRUG;

EID: 78751703225     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.11.040     Document Type: Review
Times cited : (49)

References (58)
  • 1
    • 70349482953 scopus 로고    scopus 로고
    • Novel trends in high-throughput screening
    • Mayr L.M., Bojanic D. Novel trends in high-throughput screening. Curr. Opin. Pharmacol. 2009, 9:580-588.
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 580-588
    • Mayr, L.M.1    Bojanic, D.2
  • 2
    • 12844283957 scopus 로고    scopus 로고
    • High-throughput drug discovery: what can we expect from HTS?
    • Gribbon P., Sewing A. High-throughput drug discovery: what can we expect from HTS?. Drug Discov. Today 2005, 10:17-22.
    • (2005) Drug Discov. Today , vol.10 , pp. 17-22
    • Gribbon, P.1    Sewing, A.2
  • 3
    • 70349486038 scopus 로고    scopus 로고
    • Biophysical techniques for ligand screening and drug design
    • Renaud J.-P., Delsuc M.-A. Biophysical techniques for ligand screening and drug design. Curr. Opin. Pharmacol. 2009, 9:622-628.
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 622-628
    • Renaud, J.-P.1    Delsuc, M.-A.2
  • 4
    • 33745809902 scopus 로고    scopus 로고
    • Hit discovery and hit-to-lead approaches
    • Keserü G.M., Makara G.M. Hit discovery and hit-to-lead approaches. Drug Discov. Today 2006, 11:741-748.
    • (2006) Drug Discov. Today , vol.11 , pp. 741-748
    • Keserü, G.M.1    Makara, G.M.2
  • 5
    • 47049102615 scopus 로고    scopus 로고
    • Affinity selection-mass spectrometry and its emerging application to the high throughput screening of G protein-coupled receptors
    • Whitehurst C.E., Annis D.A. Affinity selection-mass spectrometry and its emerging application to the high throughput screening of G protein-coupled receptors. Comb. Chem. High Throughput Screen. 2008, 11:427-438.
    • (2008) Comb. Chem. High Throughput Screen. , vol.11 , pp. 427-438
    • Whitehurst, C.E.1    Annis, D.A.2
  • 6
    • 18344396306 scopus 로고    scopus 로고
    • Biochemical applications of mass spectrometry in pharmaceutical drug discovery
    • Geoghegan K.F., Kelly M.A. Biochemical applications of mass spectrometry in pharmaceutical drug discovery. Mass Spectrom. Rev. 2005, 24:347-366.
    • (2005) Mass Spectrom. Rev. , vol.24 , pp. 347-366
    • Geoghegan, K.F.1    Kelly, M.A.2
  • 7
    • 77949887336 scopus 로고    scopus 로고
    • Biointeraction affinity chromatography: general principles and recent developments
    • Schiel J.E., Joseph K.S., Hage D.S. Biointeraction affinity chromatography: general principles and recent developments. Adv. Chromatogr. 2010, 48:145-193.
    • (2010) Adv. Chromatogr. , vol.48 , pp. 145-193
    • Schiel, J.E.1    Joseph, K.S.2    Hage, D.S.3
  • 8
    • 0032895673 scopus 로고    scopus 로고
    • Affinity chromatography: a review of clinical applications
    • Hage D.S. Affinity chromatography: a review of clinical applications. Clin. Chem. 1999, 45:593-615.
    • (1999) Clin. Chem. , vol.45 , pp. 593-615
    • Hage, D.S.1
  • 9
    • 65449136735 scopus 로고    scopus 로고
    • Characterization of drug-protein interactions in blood using high-performance affinity chromatography
    • Hage D.S., Jackson A., Sobansky M.R., Schiel J.E., Yoo M.J., Joseph K.S. Characterization of drug-protein interactions in blood using high-performance affinity chromatography. J. Sep. Sci. 2009, 32:835-853.
    • (2009) J. Sep. Sci. , vol.32 , pp. 835-853
    • Hage, D.S.1    Jackson, A.2    Sobansky, M.R.3    Schiel, J.E.4    Yoo, M.J.5    Joseph, K.S.6
  • 11
    • 0016640348 scopus 로고
    • Quantitative analysis of affinity chromatography of trypsin. A new technique for investigation of protein-ligand interaction
    • Kasai K., Ishii S. Quantitative analysis of affinity chromatography of trypsin. A new technique for investigation of protein-ligand interaction. J. Biochem. 1975, 77:261-264.
    • (1975) J. Biochem. , vol.77 , pp. 261-264
    • Kasai, K.1    Ishii, S.2
  • 12
    • 0033521531 scopus 로고    scopus 로고
    • Micro-scale frontal affinity chromatography with mass spectrometry detection: a new method for the screening of compound libraries
    • Schriemer D.C., Bundle D.R., Li L., Hindsgaul O. Micro-scale frontal affinity chromatography with mass spectrometry detection: a new method for the screening of compound libraries. Angew. Chem. Int. Ed. 1998, 37:3383-3387.
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 3383-3387
    • Schriemer, D.C.1    Bundle, D.R.2    Li, L.3    Hindsgaul, O.4
  • 13
    • 28544435359 scopus 로고    scopus 로고
    • Emerging challenges in ligand discovery: new opportunities for chromatographic assay
    • Ng E.S., Schriemer D.C. Emerging challenges in ligand discovery: new opportunities for chromatographic assay. Expert Rev. Proteomics 2005, 2:891-900.
    • (2005) Expert Rev. Proteomics , vol.2 , pp. 891-900
    • Ng, E.S.1    Schriemer, D.C.2
  • 15
    • 67049160794 scopus 로고    scopus 로고
    • Target-based drug discovery: the emerging success of frontal affinity chromatography coupled to mass spectrometry
    • Calleri E., Temporini C., Caccialanza G., Massolini G. Target-based drug discovery: the emerging success of frontal affinity chromatography coupled to mass spectrometry. ChemMedChem 2009, 4:905-916.
    • (2009) ChemMedChem , vol.4 , pp. 905-916
    • Calleri, E.1    Temporini, C.2    Caccialanza, G.3    Massolini, G.4
  • 17
    • 0036162711 scopus 로고    scopus 로고
    • Immobilized receptor- and transporter-based liquid chromatographic phases for on-line pharmacological and biochemical studies: a mini-review
    • Moaddel R., Lu L., Baynham M., Wainer I.W. Immobilized receptor- and transporter-based liquid chromatographic phases for on-line pharmacological and biochemical studies: a mini-review. J. Chromatogr. B 2002, 768:41-53.
    • (2002) J. Chromatogr. B , vol.768 , pp. 41-53
    • Moaddel, R.1    Lu, L.2    Baynham, M.3    Wainer, I.W.4
  • 18
    • 2342537811 scopus 로고    scopus 로고
    • Determination of binding constants by affinity chromatography and enzymes
    • Winzor D.J. Determination of binding constants by affinity chromatography and enzymes. J. Chromatogr. A 2004, 1037:351-367.
    • (2004) J. Chromatogr. A , vol.1037 , pp. 351-367
    • Winzor, D.J.1
  • 19
    • 0242579902 scopus 로고    scopus 로고
    • Drug affinity to immobilized target bio-polymers by high-performance liquid chromatography and capillary electrophoresis
    • Bertucci C., Bartolini M., Gotti R., Andrisano V. Drug affinity to immobilized target bio-polymers by high-performance liquid chromatography and capillary electrophoresis. J. Chromatogr. B 2003, 797:111-129.
    • (2003) J. Chromatogr. B , vol.797 , pp. 111-129
    • Bertucci, C.1    Bartolini, M.2    Gotti, R.3    Andrisano, V.4
  • 20
    • 33645216922 scopus 로고    scopus 로고
    • Development of immobilized membrane-based affinity columns for use in the online characterization of membrane bound proteins and for targeted affinity isolations
    • Moaddel R., Wainer I.W. Development of immobilized membrane-based affinity columns for use in the online characterization of membrane bound proteins and for targeted affinity isolations. Anal. Chim. Acta 2006, 564:97-105.
    • (2006) Anal. Chim. Acta , vol.564 , pp. 97-105
    • Moaddel, R.1    Wainer, I.W.2
  • 22
    • 33847628853 scopus 로고    scopus 로고
    • Automated multiple ligand screening by frontal affinity chromatography-mass spectrometry (FAC-MS)
    • Ng W., Dai J.-R., Slon-Usakiewicz J.J., Redden P.R., Pasternak A., Reid N. Automated multiple ligand screening by frontal affinity chromatography-mass spectrometry (FAC-MS). J. Biomol. Screen. 2007, 12:167-174.
    • (2007) J. Biomol. Screen. , vol.12 , pp. 167-174
    • Ng, W.1    Dai, J.-R.2    Slon-Usakiewicz, J.J.3    Redden, P.R.4    Pasternak, A.5    Reid, N.6
  • 23
    • 0344738554 scopus 로고    scopus 로고
    • Frontal affinity chromatography combined on-line with mass spectrometry: a tool for the binding study of different epidermal growth factor receptor inhibitors
    • Zhu L., Chen L., Luo H., Xu X. Frontal affinity chromatography combined on-line with mass spectrometry: a tool for the binding study of different epidermal growth factor receptor inhibitors. Anal. Chem. 2003, 75:6388-6393.
    • (2003) Anal. Chem. , vol.75 , pp. 6388-6393
    • Zhu, L.1    Chen, L.2    Luo, H.3    Xu, X.4
  • 24
    • 0042977487 scopus 로고    scopus 로고
    • Frontal immunoaffinity chromatography with mass spectrometric detection: a method for finding active compounds from traditional Chinese herbs
    • Luo H., Chen L., Li Z., Ding Z., Xu X. Frontal immunoaffinity chromatography with mass spectrometric detection: a method for finding active compounds from traditional Chinese herbs. Anal. Chem. 2003, 75:3994-3998.
    • (2003) Anal. Chem. , vol.75 , pp. 3994-3998
    • Luo, H.1    Chen, L.2    Li, Z.3    Ding, Z.4    Xu, X.5
  • 25
    • 77954086965 scopus 로고    scopus 로고
    • Immobilization methods for affinity chromatography
    • CRC Press/Taylor & Francis, (chapter 3), D.S. Hage (Ed.)
    • Kim H.S., Hage D.S. Immobilization methods for affinity chromatography. Handbook of Affinity Chromatography 2005, CRC Press/Taylor & Francis, (chapter 3). D.S. Hage (Ed.).
    • (2005) Handbook of Affinity Chromatography
    • Kim, H.S.1    Hage, D.S.2
  • 26
    • 33748418031 scopus 로고    scopus 로고
    • Affinity monolith chromatography
    • Mallik R., Hage D.S. Affinity monolith chromatography. J. Sep. Sci. 2006, 29:1686-1704.
    • (2006) J. Sep. Sci. , vol.29 , pp. 1686-1704
    • Mallik, R.1    Hage, D.S.2
  • 27
    • 0029839008 scopus 로고    scopus 로고
    • Immobilized membrane vesicle or proteoliposome affinity chromatography. Frontal analysis of interactions of cytochalasin B and d-glucose with the human red cell glucose transporter
    • Brekkan E., Lundqvist A., Lundahl P. Immobilized membrane vesicle or proteoliposome affinity chromatography. Frontal analysis of interactions of cytochalasin B and d-glucose with the human red cell glucose transporter. Biochemistry 1996, 35:12141-12145.
    • (1996) Biochemistry , vol.35 , pp. 12141-12145
    • Brekkan, E.1    Lundqvist, A.2    Lundahl, P.3
  • 28
    • 0036162425 scopus 로고    scopus 로고
    • Immobilized-biomembrane affinity chromatography for binding studies of membrane proteins
    • Gottschalk I., Lagerquist C., Zuo S.-S., Lundqvist A., Lundahl P. Immobilized-biomembrane affinity chromatography for binding studies of membrane proteins. J. Chromatogr. B 2002, 768:31-40.
    • (2002) J. Chromatogr. B , vol.768 , pp. 31-40
    • Gottschalk, I.1    Lagerquist, C.2    Zuo, S.-S.3    Lundqvist, A.4    Lundahl, P.5
  • 30
    • 59849097146 scopus 로고    scopus 로고
    • The preparation and development of cellular membrane affinity chromatography columns
    • Moaddel R., Wainer I.W. The preparation and development of cellular membrane affinity chromatography columns. Nat. Protoc. 2009, 4:197-205.
    • (2009) Nat. Protoc. , vol.4 , pp. 197-205
    • Moaddel, R.1    Wainer, I.W.2
  • 32
    • 17644378085 scopus 로고    scopus 로고
    • Comparison of determination of drug-muscarinic receptor affinity by cell membrane chromatography and by radioligand binding assay with the cerebrum membrane of the rat
    • Yuan B.X., Hou J., Yang G.D., Zhao L.M., He L. Comparison of determination of drug-muscarinic receptor affinity by cell membrane chromatography and by radioligand binding assay with the cerebrum membrane of the rat. Chromatographia 2005, 619:381-384.
    • (2005) Chromatographia , vol.619 , pp. 381-384
    • Yuan, B.X.1    Hou, J.2    Yang, G.D.3    Zhao, L.M.4    He, L.5
  • 33
    • 15444378195 scopus 로고    scopus 로고
    • The preparation of HEK293 α1A or HEK293 α1B cell membrane stationary phase and the chromatographic affinity study of ligands of α1 adrenoreceptor
    • Yu W., Yuan B., Deng X., He L., Youyi Z., Qide H. The preparation of HEK293 α1A or HEK293 α1B cell membrane stationary phase and the chromatographic affinity study of ligands of α1 adrenoreceptor. Anal. Biochem. 2005, 339:198-205.
    • (2005) Anal. Biochem. , vol.339 , pp. 198-205
    • Yu, W.1    Yuan, B.2    Deng, X.3    He, L.4    Youyi, Z.5    Qide, H.6
  • 34
    • 33751162377 scopus 로고    scopus 로고
    • Comparison of alpha1-adrenergic receptor cell-membrane stationary phases prepared from expressed cell line and from rabbit hepatocytes
    • Wang Y., Yuan B., Deng X., He L., Wang S., Zhang Y., Han Q. Comparison of alpha1-adrenergic receptor cell-membrane stationary phases prepared from expressed cell line and from rabbit hepatocytes. Anal. Bioanal. Chem. 2006, 386:2003-2011.
    • (2006) Anal. Bioanal. Chem. , vol.386 , pp. 2003-2011
    • Wang, Y.1    Yuan, B.2    Deng, X.3    He, L.4    Wang, S.5    Zhang, Y.6    Han, Q.7
  • 35
    • 67049145391 scopus 로고    scopus 로고
    • Frontal analysis of cell-membrane chromatography for the determination of drug-α1D adrenergic receptor affinity
    • Zeng A., Yuan B., Wang C., Yang G., He L. Frontal analysis of cell-membrane chromatography for the determination of drug-α1D adrenergic receptor affinity. J. Chromatogr. B 2009, 877:1833-1837.
    • (2009) J. Chromatogr. B , vol.877 , pp. 1833-1837
    • Zeng, A.1    Yuan, B.2    Wang, C.3    Yang, G.4    He, L.5
  • 36
    • 42149117753 scopus 로고    scopus 로고
    • Solid-phase assays for small molecule screening using sol-gel entrapped proteins
    • Lebert J.M., Forsberg E.M., Brennan J.D. Solid-phase assays for small molecule screening using sol-gel entrapped proteins. Biochem. Cell Biol. 2008, 86:100-110.
    • (2008) Biochem. Cell Biol. , vol.86 , pp. 100-110
    • Lebert, J.M.1    Forsberg, E.M.2    Brennan, J.D.3
  • 37
    • 38649120829 scopus 로고    scopus 로고
    • Drugs and their molecular targets: an updated overview
    • Landry Y., Gies J.-P. Drugs and their molecular targets: an updated overview. Fundam. Clin. Pharmacol. 2008, 22:F1-F18.
    • (2008) Fundam. Clin. Pharmacol. , vol.22
    • Landry, Y.1    Gies, J.-P.2
  • 38
    • 13244289976 scopus 로고    scopus 로고
    • Conformational mobility of immobilized alpha3beta2, alpha3beta4, alpha4beta2, and alpha4beta4 nicotinic acetylcholine receptors
    • Moaddel R., Jozwiak K., Whittington K., Wainer I.W. Conformational mobility of immobilized alpha3beta2, alpha3beta4, alpha4beta2, and alpha4beta4 nicotinic acetylcholine receptors. Anal. Chem. 2005, 77:895-901.
    • (2005) Anal. Chem. , vol.77 , pp. 895-901
    • Moaddel, R.1    Jozwiak, K.2    Whittington, K.3    Wainer, I.W.4
  • 39
    • 0032213347 scopus 로고    scopus 로고
    • Immobilized nicotinic receptor stationary phase for on-line liquid chromatographic determination of drug-receptor affinitie
    • Zhang Y., Xiao Y., Kellar K.J., Wainer I.W. Immobilized nicotinic receptor stationary phase for on-line liquid chromatographic determination of drug-receptor affinitie. Anal. Biochem. 1998, 264:22-25.
    • (1998) Anal. Biochem. , vol.264 , pp. 22-25
    • Zhang, Y.1    Xiao, Y.2    Kellar, K.J.3    Wainer, I.W.4
  • 40
    • 0032971314 scopus 로고    scopus 로고
    • Liquid chromatographic studies with immobilized neuronal nicotinic acetylcholine receptor stationary phases: effects of receptor subtypes, pH and ionic strength on drug-receptor interactions
    • WainerF I.W., Zhang Y., Xiao Y., Kellar K.J. Liquid chromatographic studies with immobilized neuronal nicotinic acetylcholine receptor stationary phases: effects of receptor subtypes, pH and ionic strength on drug-receptor interactions. J. Chromatogr. B 1999, 724:65-72.
    • (1999) J. Chromatogr. B , vol.724 , pp. 65-72
    • WainerF, I.W.1    Zhang, Y.2    Xiao, Y.3    Kellar, K.J.4
  • 41
    • 8844232736 scopus 로고    scopus 로고
    • On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the alpha3beta4- and alpha4beta2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases
    • Moaddel R., Jozwiak K., Yamaguchi R., Cobello C., Whittington K., Sarkar T.K., Basak S., Wainer I.W. On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the alpha3beta4- and alpha4beta2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases. J. Chromatogr. B 2004, 813:235-240.
    • (2004) J. Chromatogr. B , vol.813 , pp. 235-240
    • Moaddel, R.1    Jozwiak, K.2    Yamaguchi, R.3    Cobello, C.4    Whittington, K.5    Sarkar, T.K.6    Basak, S.7    Wainer, I.W.8
  • 42
    • 41149083146 scopus 로고    scopus 로고
    • Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type
    • Moaddel R., Oliveira R.V., Kimura T., Hyppolite P., Juhaszova M., Xiao Y., Kellar K.J., Bernier M., Wainer I.W. Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type. Anal. Chem. 2008, 80:48-54.
    • (2008) Anal. Chem. , vol.80 , pp. 48-54
    • Moaddel, R.1    Oliveira, R.V.2    Kimura, T.3    Hyppolite, P.4    Juhaszova, M.5    Xiao, Y.6    Kellar, K.J.7    Bernier, M.8    Wainer, I.W.9
  • 43
    • 0036147555 scopus 로고    scopus 로고
    • Multiple receptor liquid chromatographic stationary phases: the co-immobilization of nicotinic receptors, the g-amino-butyric acid receptors, the N-methyl d-aspartate receptors
    • Moaddel R., Cloix J.-F., Ertem G., Wainer I.W. Multiple receptor liquid chromatographic stationary phases: the co-immobilization of nicotinic receptors, the g-amino-butyric acid receptors, the N-methyl d-aspartate receptors. Pharm. Res. 2002, 19:104-107.
    • (2002) Pharm. Res. , vol.19 , pp. 104-107
    • Moaddel, R.1    Cloix, J.-F.2    Ertem, G.3    Wainer, I.W.4
  • 44
    • 56449110129 scopus 로고    scopus 로고
    • Characterization of a multiple ligand-gated ion channel cellular membrane affinity chromatography column and identification of endogenously expressed receptors in astrocytoma cell lines
    • Kitabatake T., Moaddel R., Cole R., Gandhari M., Frazier C., Hartenstein J., Rosenberg A., Bernier M., Wainer I.W. Characterization of a multiple ligand-gated ion channel cellular membrane affinity chromatography column and identification of endogenously expressed receptors in astrocytoma cell lines. Anal. Chem. 2008, 80:8673-8680.
    • (2008) Anal. Chem. , vol.80 , pp. 8673-8680
    • Kitabatake, T.1    Moaddel, R.2    Cole, R.3    Gandhari, M.4    Frazier, C.5    Hartenstein, J.6    Rosenberg, A.7    Bernier, M.8    Wainer, I.W.9
  • 45
    • 77953807865 scopus 로고    scopus 로고
    • Investigation of calcium antagonist-L-type calcium channel interactions by a vascular smooth muscle cell membrane chromatography method
    • Du H., He J., Wang S., He L. Investigation of calcium antagonist-L-type calcium channel interactions by a vascular smooth muscle cell membrane chromatography method. Anal. Bioanal. Chem. 2010, 397:1947-1953.
    • (2010) Anal. Bioanal. Chem. , vol.397 , pp. 1947-1953
    • Du, H.1    He, J.2    Wang, S.3    He, L.4
  • 46
    • 61649096359 scopus 로고    scopus 로고
    • G-protein-coupled receptor-focused drug discovery using a target class platform approach
    • Heilker R., Wolff M., Tautermann C.S., Bieler M. G-protein-coupled receptor-focused drug discovery using a target class platform approach. Drug Discov. Today 2009, 14:231-240.
    • (2009) Drug Discov. Today , vol.14 , pp. 231-240
    • Heilker, R.1    Wolff, M.2    Tautermann, C.S.3    Bieler, M.4
  • 47
    • 10644292741 scopus 로고    scopus 로고
    • G-protein-coupled receptor chromatographic stationary phases. 2. Ligand-induced conformational mobility in an immobilized β2-adrenergic receptor
    • Beigi F., Chakir K., Xiao R.-P., Wainer I.W. G-protein-coupled receptor chromatographic stationary phases. 2. Ligand-induced conformational mobility in an immobilized β2-adrenergic receptor. Anal. Chem. 2004, 76:7187-7193.
    • (2004) Anal. Chem. , vol.76 , pp. 7187-7193
    • Beigi, F.1    Chakir, K.2    Xiao, R.-P.3    Wainer, I.W.4
  • 48
    • 34147098379 scopus 로고    scopus 로고
    • The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening
    • Moaddel R., Calleri E., Massolini G., Frazier C.R., Wainer I.W. The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening. Anal. Biochem. 2007, 364:216-218.
    • (2007) Anal. Biochem. , vol.364 , pp. 216-218
    • Moaddel, R.1    Calleri, E.2    Massolini, G.3    Frazier, C.R.4    Wainer, I.W.5
  • 49
    • 77649183824 scopus 로고    scopus 로고
    • Synthesis and characterization of a cellular membrane affinity chromatography column containing histamine 1 and P2Y1 receptors: a multiple G-protein coupled receptor column
    • Moaddel R., Musyimi H.K., Sanghvi M., Bashore C., Frazier C.R., Khadeer M., Bhatia P., Wainer I.W. Synthesis and characterization of a cellular membrane affinity chromatography column containing histamine 1 and P2Y1 receptors: a multiple G-protein coupled receptor column. J. Pharm. Biomed. Anal. 2010, 52:416-419.
    • (2010) J. Pharm. Biomed. Anal. , vol.52 , pp. 416-419
    • Moaddel, R.1    Musyimi, H.K.2    Sanghvi, M.3    Bashore, C.4    Frazier, C.R.5    Khadeer, M.6    Bhatia, P.7    Wainer, I.W.8
  • 50
    • 56249133294 scopus 로고    scopus 로고
    • Development of an immobilized GPR17 receptor stationary phase for binding determination using frontal affinity chromatography coupled to mass spectrometry
    • Temporini C., Ceruti S., Calleri E., Ferrario S., Moaddel R., Abbracchio M.P., Massolini G. Development of an immobilized GPR17 receptor stationary phase for binding determination using frontal affinity chromatography coupled to mass spectrometry. Anal. Biochem. 2009, 384:123-129.
    • (2009) Anal. Biochem. , vol.384 , pp. 123-129
    • Temporini, C.1    Ceruti, S.2    Calleri, E.3    Ferrario, S.4    Moaddel, R.5    Abbracchio, M.P.6    Massolini, G.7
  • 52
    • 0041336706 scopus 로고    scopus 로고
    • Syntheses of immobilized G protein-coupled receptor chromatographic stationary phases: characterization of immobilized mu and kappa opioid receptors
    • Beigi F., Wainer I.W. Syntheses of immobilized G protein-coupled receptor chromatographic stationary phases: characterization of immobilized mu and kappa opioid receptors. Anal. Chem. 2003, 75:4480-4485.
    • (2003) Anal. Chem. , vol.75 , pp. 4480-4485
    • Beigi, F.1    Wainer, I.W.2
  • 55
    • 33646772536 scopus 로고    scopus 로고
    • The nuclear receptor superfamily and drug discovery
    • Moore J.T., Collins J.L., Pearce K.H. The nuclear receptor superfamily and drug discovery. ChemMedChem 2006, 1:504-523.
    • (2006) ChemMedChem , vol.1 , pp. 504-523
    • Moore, J.T.1    Collins, J.L.2    Pearce, K.H.3
  • 56
    • 77950519927 scopus 로고    scopus 로고
    • Neclear receptors in analytics-a fruitful joint venture or wasteful futility?
    • Fechner P., Gauglitz G., Gustafsson J.-A. Neclear receptors in analytics-a fruitful joint venture or wasteful futility?. Trends Anal. Chem. 2010, 4:297-305.
    • (2010) Trends Anal. Chem. , vol.4 , pp. 297-305
    • Fechner, P.1    Gauglitz, G.2    Gustafsson, J.-A.3
  • 57
    • 77954863312 scopus 로고    scopus 로고
    • Synthesis and characterization of liquid chromatographic columns containing the immobilized ligand binding domain of the estrogen related receptor alpha and estrogen related receptor gamma
    • Sanghvi M., Moaddel R., Frazier C., Wainer I.W. Synthesis and characterization of liquid chromatographic columns containing the immobilized ligand binding domain of the estrogen related receptor alpha and estrogen related receptor gamma. J. Pharm. Biomed. Anal. 2010, 53:777-780.
    • (2010) J. Pharm. Biomed. Anal. , vol.53 , pp. 777-780
    • Sanghvi, M.1    Moaddel, R.2    Frazier, C.3    Wainer, I.W.4
  • 58
    • 0038353368 scopus 로고    scopus 로고
    • Frontal affinity chromatography-mass spectrometry assay technology for multiple stages of drug discovery: applications of a chromatographic biosensor
    • Chan N.W., Lewis D.F., Rosner P.J., Kelly M.A., Schriemer D.C. Frontal affinity chromatography-mass spectrometry assay technology for multiple stages of drug discovery: applications of a chromatographic biosensor. Anal. Biochem. 2003, 319:1-12.
    • (2003) Anal. Biochem. , vol.319 , pp. 1-12
    • Chan, N.W.1    Lewis, D.F.2    Rosner, P.J.3    Kelly, M.A.4    Schriemer, D.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.