Frontal analysis of cell-membrane chromatography for determination of drug-α1D adrenergic receptor affinity

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 20-21, 2009, Pages 1833-1837

  Zeng, Aiguo ^a   Yuan, Bingxiang ^a   Wang, Changhe ^a   Yang, Guangde ^a   He, Langchong ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

1D adrenergic receptor; Cell membrane chromatography; Dissociation constant; Frontal analysis; Rat aorta

Indexed keywords

ADRENERGIC RECEPTORS; AFFINITY RANK; BINDING ASSAYS; DIRECT DETERMINATION; DISSOCIATION CONSTANT; DRUG BINDING; DRUG-RECEPTOR BINDING; FRONTAL ANALYSIS; FRONTAL CHROMATOGRAPHY; GOOD CORRELATIONS; LIGAND-RECEPTOR INTERACTIONS; MEMBRANE CHROMATOGRAPHY; POROUS SILICA; RADIOLIGAND; RELATIVE BINDING AFFINITY; STATIONARY PHASE;

BINDING ENERGY; BLOOD VESSELS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; CYTOLOGY; DISSOCIATION; DRUG INTERACTIONS; MEMBRANES; PHENOLS; SILICA;

CELL MEMBRANES;

5 METHYLURAPIDIL; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA ADRENERGIC RECEPTOR; METHOXAMINE; OXYMETAZOLINE; PHENTOLAMINE; PRAZOSIN; RADIOLIGAND; RECEPTOR SUBUNIT; SILICON DIOXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CELL MEMBRANE; CLONE; DISSOCIATION CONSTANT; DRUG RECEPTOR BINDING; LIGAND BINDING; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RECEPTOR AFFINITY; REPRODUCIBILITY;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; AORTA, THORACIC; BINDING SITES; CELL MEMBRANE; CHROMATOGRAPHY, AFFINITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1;

RATTUS;

EID: 67049145391     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.05.021     Document Type: Article

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