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For more references on metal catalyzed nitrile hydration, see ref. 8. See also
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36
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78751627490
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-
The same reaction in was done in THF in order to obtain the THF analogues complex. Unfortunately, these efforts remained unsuccessful
-
The same reaction in was done in THF in order to obtain the THF analogues complex. Unfortunately, these efforts remained unsuccessful.
-
-
-
-
37
-
-
78751631640
-
-
contrast to cationic nitrile complexes, the synthesis of [Au(OH)(IPr)] is realized without the use of any silver salts
-
In contrast to cationic nitrile complexes, the synthesis of [Au(OH)(IPr)] is realized without the use of any silver salts.
-
-
-
-
38
-
-
78751630926
-
-
4 in toluene lead to identical isolated yields
-
4 in toluene lead to identical isolated yields.
-
-
-
-
39
-
-
78751607896
-
-
Washing the organic phase with brine resulted in full conversion into [AuCl(IPr)]
-
Washing the organic phase with brine resulted in full conversion into [AuCl(IPr)].
-
-
-
-
40
-
-
77955683408
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41
-
-
78751638627
-
-
DFT values for 2: AuAu 3.886; Auï£ ¿O 2.081; AuC 1.974; OH 0.976 à; Au-O-Au 137.9; Au-O-H 109.7°
-
DFT values for 2: AuAu 3.886; Auï£ ¿O 2.081; AuC 1.974; OH 0.976 à; Au-O-Au 137.9; Au-O-H 109.7°.
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78751635332
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-
We suspect at this stage that 3 could be a reservoir for the catalytically active mononuclear cationic gold species
-
We suspect at this stage that 3 could be a reservoir for the catalytically active mononuclear cationic gold species.
-
-
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46
-
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78751625767
-
-
A rudimentary test proofed 2 active in nitrile hydration. See reference [10]
-
A rudimentary test proofed 2 active in nitrile hydration. See reference [10].
-
-
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47
-
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78751618546
-
-
This conversion is poor but the presence of any activity of 1 under neutral condition is worthy of further investigation
-
This conversion is poor but the presence of any activity of 1 under neutral condition is worthy of further investigation.
-
-
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48
-
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78751608306
-
-
Of note, Bayler-Schmidtbaur complexes proofed already active in catalysis. For recent examples, see
-
Of note, Bayler-Schmidtbaur complexes proofed already active in catalysis. For recent examples, see
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78751623357
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4 into 3 occurs under these reaction conditions and result in lower conversions than when using 4 under these "unoptimized" conditions
-
4 into 3 occurs under these reaction conditions and result in lower conversions than when using 4 under these "unoptimized" conditions.
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78751622271
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2 results in full conversion into catalyst 2
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2 results in full conversion into catalyst 2.
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-
6 in nitrile hydration resulted in identical conversions.
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