Gamma-secretase complexes regulate the responses of human pancreatic ductal adenocarcinoma cells to taxanes

Anticancer Research

Volumn 30, Issue 12, 2010, Pages 4999-5010

  Tasaka, Takehiko ^a   Akiyoshi, Takashi ^a   Yamaguchi, Koji ^b   Tanaka, Masao ^c   Onishi, Hideya ^a   Katano, Mitsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b CANCER INSTITUTE HOSPITAL   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

secretase; Apoptosis; Cell cycle; Chemoresistance; G0 G1; Pancreatic ductal adenocarcinoma cells; Presenilin 1; Presenilin 2; Taxanes

Indexed keywords

CELL CYCLE PROTEIN; DOCETAXEL; GAMMA SECRETASE; NOTCH RECEPTOR; PACLITAXEL; PRESENILIN 1; PRESENILIN 2; PROTEIN CDC 2; SMALL INTERFERING RNA; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; DRUG EFFECT; DRUG RESPONSE; GENE SILENCING; HUMAN; HUMAN CELL; PANCREAS CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMYLOID PRECURSOR PROTEIN SECRETASES; APOPTOSIS; CARCINOMA, PANCREATIC DUCTAL; CELL CYCLE; DIPEPTIDES; DRUG SYNERGISM; ENZYME INHIBITORS; HUMANS; PANCREATIC NEOPLASMS; PRESENILIN-1; PRESENILIN-2; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TAXOIDS;

EID: 78751478264     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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