-
1
-
-
51849128358
-
Class I PI3K in oncogenic cellular transformation
-
Zhao L, Vogt PK (2008) Class I PI3K in oncogenic cellular transformation. Oncogene 27: 5486-5496.
-
(2008)
Oncogene
, vol.27
, pp. 5486-5496
-
-
Zhao, L.1
Vogt, P.K.2
-
2
-
-
33847314539
-
The phosphatidyl inositol 3-kinase signaling network: Implications for human breast cancer
-
Dillon RL, White DE, Muller WJ (2007) The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer. Oncogene 26: 1338-1345.
-
(2007)
Oncogene
, vol.26
, pp. 1338-1345
-
-
Dillon, R.L.1
White, D.E.2
Muller, W.J.3
-
3
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, et al. (2004) High frequency of mutations of the PIK3CA gene in human cancers. Science 304: 554.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
-
4
-
-
33344462540
-
Mutation of the PIK3CA oncogene in human cancers
-
Karakas B, Bachman KE, Park BH (2006) Mutation of the PIK3CA oncogene in human cancers. Br J Cancer 94: 455-459.
-
(2006)
Br J Cancer
, vol.94
, pp. 455-459
-
-
Karakas, B.1
Bachman, K.E.2
Park, B.H.3
-
5
-
-
29444449785
-
The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells
-
Zhao JJ, Liu Z, Wang L, Shin E, Loda MF, et al. (2005) The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells. Proc Natl Acad Sci U S A 102: 18443-18448.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18443-18448
-
-
Zhao, J.J.1
Liu, Z.2
Wang, L.3
Shin, E.4
Loda, M.F.5
-
6
-
-
31944444234
-
Cancer-specific mutations in PIK3CA are oncogenic in vivo
-
Bader AG, Kang S, Vogt PK (2006) Cancer-specific mutations in PIK3CA are oncogenic in vivo. Proc Natl Acad Sci U S A 103: 1475-1479.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1475-1479
-
-
Bader, A.G.1
Kang, S.2
Vogt, P.K.3
-
7
-
-
20144387695
-
PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
-
Saal LH, Holm K, Maurer M, Memeo L, Su T, et al. (2005) PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. Cancer Res 65: 2554-2559.
-
(2005)
Cancer Res
, vol.65
, pp. 2554-2559
-
-
Saal, L.H.1
Holm, K.2
Maurer, M.3
Memeo, L.4
Su, T.5
-
8
-
-
51049118140
-
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
-
Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, Neve RM, Kuo WL, et al. (2008) An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. Cancer Res 68: 6084-6091.
-
(2008)
Cancer Res
, vol.68
, pp. 6084-6091
-
-
Stemke-Hale, K.1
Gonzalez-Angulo, A.M.2
Lluch, A.3
Neve, R.M.4
Kuo, W.L.5
-
10
-
-
0141542480
-
Real-time reverse transcription-PCR assay for future management of ERBB2-based clinical applications
-
Bieche I, Onody P, Laurendeau I, Olivi M, Vidaud D, et al. (1999) Real-time reverse transcription-PCR assay for future management of ERBB2-based clinical applications. Clin Chem 45: 1148-1156.
-
(1999)
Clin Chem
, vol.45
, pp. 1148-1156
-
-
Bieche, I.1
Onody, P.2
Laurendeau, I.3
Olivi, M.4
Vidaud, D.5
-
11
-
-
0016772212
-
Comparison of the predicted and observed secondary structure of T4 phage lysozyme
-
Matthews BW (1975) Comparison of the predicted and observed secondary structure of T4 phage lysozyme. Biochim Biophys Acta 405: 442-451.
-
(1975)
Biochim Biophys Acta
, vol.405
, pp. 442-451
-
-
Matthews, B.W.1
-
12
-
-
0032716985
-
Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer
-
Gee JM, Robertson JF, Ellis IO, Nicholson RI, Hurst HC (1999) Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer. J Pathol 189: 514-520.
-
(1999)
J Pathol
, vol.189
, pp. 514-520
-
-
Gee, J.M.1
Robertson, J.F.2
Ellis, I.O.3
Nicholson, R.I.4
Hurst, H.C.5
-
13
-
-
67349255703
-
Dual expression of alpha-tocopherol-associated protein and estrogen receptor in normal/benign human breast luminal cells and the downregulation of alpha-tocopherolassociated protein in estrogen-receptor-positive breast carcinomas
-
Johnykutty S, Tang P, Zhao H, Hicks DG, Yeh S, et al. (2009) Dual expression of alpha-tocopherol-associated protein and estrogen receptor in normal/benign human breast luminal cells and the downregulation of alpha-tocopherolassociated protein in estrogen-receptor-positive breast carcinomas. Mod Pathol 22: 770-775.
-
(2009)
Mod Pathol
, vol.22
, pp. 770-775
-
-
Johnykutty, S.1
Tang, P.2
Zhao, H.3
Hicks, D.G.4
Yeh, S.5
-
14
-
-
0344413009
-
Id4 regulates mammary epithelial cell growth and differentiation and is overexpressed in rat mammary gland carcinomas
-
Shan L, Yu M, Qiu C, Snyderwine EG (2003) Id4 regulates mammary epithelial cell growth and differentiation and is overexpressed in rat mammary gland carcinomas. Am J Pathol 163: 2495-2502.
-
(2003)
Am J Pathol
, vol.163
, pp. 2495-2502
-
-
Shan, L.1
Yu, M.2
Qiu, C.3
Snyderwine, E.G.4
-
15
-
-
47749089779
-
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
-
Tang W, Dodge M, Gundapaneni D, Michnoff C, Roth M, et al. (2008) A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. Proc Natl Acad Sci U S A 105: 9697-9702.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9697-9702
-
-
Tang, W.1
Dodge, M.2
Gundapaneni, D.3
Michnoff, C.4
Roth, M.5
-
17
-
-
50649109669
-
Msx2 exerts bone anabolism via canonical Wnt signaling
-
Cheng SL, Shao JS, Cai J, Sierra OL, Towler DA (2008) Msx2 exerts bone anabolism via canonical Wnt signaling. J Biol Chem 283: 20505-20522.
-
(2008)
J Biol Chem
, vol.283
, pp. 20505-20522
-
-
Cheng, S.L.1
Shao, J.S.2
Cai, J.3
Sierra, O.L.4
Towler, D.A.5
-
18
-
-
55349138386
-
ERR Mediates Tamoxifen Resistance in Novel Models of Invasive Lobular Breast Cancer
-
Riggins RB, Lan JP-J, Klimach U, Zwart A, Cavalli LR, et al. (2008) ERR Mediates Tamoxifen Resistance in Novel Models of Invasive Lobular Breast Cancer. Cancer Res 68: 8908-8917.
-
(2008)
Cancer Res
, vol.68
, pp. 8908-8917
-
-
Riggins, R.B.1
Lan, J.P.-J.2
Klimach, U.3
Zwart, A.4
Cavalli, L.R.5
-
19
-
-
39749153355
-
HER2 expression and efficacy of preoperative paclitaxel/FAC chemotherapy in breast cancer
-
Andre F, Mazouni C, Liedtke C, Kau SW, Frye D, et al. (2008) HER2 expression and efficacy of preoperative paclitaxel/FAC chemotherapy in breast cancer. Breast Cancer Res Treat 108: 183-190.
-
(2008)
Breast Cancer Res Treat
, vol.108
, pp. 183-190
-
-
Andre, F.1
Mazouni, C.2
Liedtke, C.3
Kau, S.W.4
Frye, D.5
-
20
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434: 843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
21
-
-
77449103638
-
Influence of PI-3K/Akt pathway on Wnt signalling in regulating myeloid progenitor cell proliferation. Evidence for a role of autocrine/paracrine Wnt regulation
-
Nteliopoulos G, Marley SB, Gordon MY (2009) Influence of PI-3K/Akt pathway on Wnt signalling in regulating myeloid progenitor cell proliferation. Evidence for a role of autocrine/paracrine Wnt regulation. Br J Haematol 146: 637-651.
-
(2009)
Br J Haematol
, vol.146
, pp. 637-651
-
-
Nteliopoulos, G.1
Marley, S.B.2
Gordon, M.Y.3
-
22
-
-
0041695485
-
A second canon. Functions and mechanisms of beta-catenin-independent Wnt pathway
-
Veeman MT, Axelrod JD, Moon RT (2003) A second canon. Functions and mechanisms of beta-catenin-independent Wnt pathway. Dev Cell 5: 367-77.
-
(2003)
Dev Cell
, vol.5
, pp. 367-377
-
-
Veeman, M.T.1
Axelrod, J.D.2
Moon, R.T.3
-
23
-
-
17444390878
-
WNT5A expression in human breast cancer
-
Leris AC, Roberts TR, Jiang WG, Newbold RF, Mokbel K (2005) WNT5A expression in human breast cancer. Anticancer Res 25: 731-734.
-
(2005)
Anticancer Res
, vol.25
, pp. 731-734
-
-
Leris, A.C.1
Roberts, T.R.2
Jiang, W.G.3
Newbold, R.F.4
Mokbel, K.5
-
24
-
-
67649319056
-
The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERalpha negative breast cancer
-
Ford CE, Ekström EJ, Howlin J, Andersson T (2009) The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERalpha negative breast cancer. Cell Cycle 8: 1838-42.
-
(2009)
Cell Cycle
, vol.8
, pp. 1838-1842
-
-
Ford, C.E.1
Ekström, E.J.2
Howlin, J.3
Andersson, T.4
-
25
-
-
77953422867
-
-
Loi S, Haibe-Kains B, Majjaj S, Lallemand F, Durbecq V, et al. (2010) Proc Natl Acad Sci U S A 107: 10208-13.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 10208-10213
-
-
Loi, S.1
Haibe-Kains, B.2
Majjaj, S.3
Lallemand, F.4
Durbecq, V.5
-
26
-
-
33644698339
-
WNT/PCP signaling pathway and human cancer
-
Katoh M (2005) WNT/PCP signaling pathway and human cancer. Oncol Rep 14: 1583-1588.
-
(2005)
Oncol Rep
, vol.14
, pp. 1583-1588
-
-
Katoh, M.1
-
27
-
-
0142254155
-
A transcriptional response to Wnt protein in human embryonic carcinoma cells
-
Willert J, Epping M, Pollack JR, Brown PO, Nusse R (2002) A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol 2: 8.
-
(2002)
BMC Dev Biol
, vol.2
, pp. 8
-
-
Willert, J.1
Epping, M.2
Pollack, J.R.3
Brown, P.O.4
Nusse, R.5
-
29
-
-
47249149740
-
Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
-
Bu G, Lu W, Liu CC, Selander K, Yoneda T, et al. (2008) Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases. Int J Cancer 123: 1034-1042.
-
(2008)
Int J Cancer
, vol.123
, pp. 1034-1042
-
-
Bu, G.1
Lu, W.2
Liu, C.C.3
Selander, K.4
Yoneda, T.5
-
30
-
-
58149234726
-
Cancer stem cells: Never Wnt away from the niche
-
Malanchi I, Huelsken J (2009) Cancer stem cells: never Wnt away from the niche. Curr Opin Oncol 21: 41-46.
-
(2009)
Curr Opin Oncol
, vol.21
, pp. 41-46
-
-
Malanchi, I.1
Huelsken, J.2
-
31
-
-
68849097853
-
Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy
-
Wang Y (2009) Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy. Mol Cancer Ther 8: 2103-2109.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2103-2109
-
-
Wang, Y.1
-
32
-
-
33751514601
-
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells
-
Yook JI, Li XY, Ota I, Hu C, Kim HS, et al. (2006) A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nat Cell Biol 8: 1398-1406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1398-1406
-
-
Yook, J.I.1
Li, X.Y.2
Ota, I.3
Hu, C.4
Kim, H.S.5
-
33
-
-
67650496215
-
A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer
-
DiMeo TA, Anderson K, Phadke P, Fan C, Perou CM, et al. (2009) A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. Cancer Res 69: 5364-5373.
-
(2009)
Cancer Res
, vol.69
, pp. 5364-5373
-
-
DiMeo, T.A.1
Anderson, K.2
Phadke, P.3
Fan, C.4
Perou, C.M.5
-
34
-
-
75149180021
-
Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth
-
Baryawno N, Sveinbjörnsson B, Eksborg S, Chen CS, Kogner P, et al. (2010) Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth. Cancer Res 70: 266-276.
-
(2010)
Cancer Res
, vol.70
, pp. 266-276
-
-
Baryawno, N.1
Sveinbjörnsson, B.2
Eksborg, S.3
Chen, C.S.4
Kogner, P.5
-
35
-
-
20444374445
-
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
-
Samuels Y, Diaz LA, Jr., Schmidt-Kittler O, Cummins JM, Delong L, et al. (2005) Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell 7: 561-573.
-
(2005)
Cancer Cell
, vol.7
, pp. 561-573
-
-
Samuels, Y.1
Diaz Jr., L.A.2
Schmidt-Kittler, O.3
Cummins, J.M.4
Delong, L.5
-
36
-
-
68849090815
-
Novel inhibitors of the PI3K family
-
Carnero A (2009) Novel inhibitors of the PI3K family. Expert Opin Investig Drugs 18: 1265-1277.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1265-1277
-
-
Carnero, A.1
-
37
-
-
0035869175
-
PTEN inhibits insulinstimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model
-
Weng LP, Smith WM, Brown JL, Eng C (2001) PTEN inhibits insulinstimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model. Hum Mol Genet 10: 605-616.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 605-616
-
-
Weng, L.P.1
Smith, W.M.2
Brown, J.L.3
Eng, C.4
-
38
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
Barker N, Clevers H (2006) Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov 5: 997-1014.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
39
-
-
25444519754
-
Gene expression signature of estrogen receptor alpha status in breast cancer
-
Abba MC, Hu Y, Sun H, Drake JA, Gaddis S, et al. (2005) Gene expression signature of estrogen receptor alpha status in breast cancer. BMC Genomics 6: 37.
-
(2005)
BMC Genomics
, vol.6
, pp. 37
-
-
Abba, M.C.1
Hu, Y.2
Sun, H.3
Drake, J.A.4
Gaddis, S.5
-
40
-
-
13244259275
-
Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer
-
Benaïssa M, Peyrat JP, Hornez L, Mariller C, Mazurier J, et al. (2005) Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer. Int J Cancer 114: 299-306.
-
(2005)
Int J Cancer
, vol.114
, pp. 299-306
-
-
Benaïssa, M.1
Peyrat, J.P.2
Hornez, L.3
Mariller, C.4
Mazurier, J.5
-
41
-
-
1942532186
-
Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma
-
Rieger MA, Ebner R, Bell DR, Kiessling A, Rohayem J, et al. (2004) Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. Cancer Res 64: 2357-2364.
-
(2004)
Cancer Res
, vol.64
, pp. 2357-2364
-
-
Rieger, M.A.1
Ebner, R.2
Bell, D.R.3
Kiessling, A.4
Rohayem, J.5
-
42
-
-
34250678913
-
Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins
-
Esseghir S, Kennedy A, Seedhar P, Nerurkar A, Poulsom R, et al. (2007) Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins. Clin Cancer Res 13: 3164-3173.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3164-3173
-
-
Esseghir, S.1
Kennedy, A.2
Seedhar, P.3
Nerurkar, A.4
Poulsom, R.5
-
43
-
-
20444388706
-
Microtubuleassociated protein tau: A marker of paclitaxel sensitivity in breast cancer
-
Rouzier R, Rajan R, Wagner P, Hess KR, Gold DL, et al. (2005) Microtubuleassociated protein tau: a marker of paclitaxel sensitivity in breast cancer. Proc Natl Acad Sci U S A 102: 8315-8320.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8315-8320
-
-
Rouzier, R.1
Rajan, R.2
Wagner, P.3
Hess, K.R.4
Gold, D.L.5
-
44
-
-
0034696793
-
The orphan receptor COUP-TFII regulates G2/M progression of breast cancer cells by modulating the expression/activity of p21(WAF1/CIP1), cyclin D1, and cdk2
-
Nakshatri H, Mendonca MS, Bhat-Nakshatri P, Patel NM, Goulet RJ, Jr., et al. (2000) The orphan receptor COUP-TFII regulates G2/M progression of breast cancer cells by modulating the expression/activity of p21(WAF1/CIP1), cyclin D1, and cdk2. Biochem Biophys Res Commun 270: 1144-1153.
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 1144-1153
-
-
Nakshatri, H.1
Mendonca, M.S.2
Bhat-Nakshatri, P.3
Patel, N.M.4
Goulet Jr., R.J.5
-
45
-
-
3442877538
-
Expression of chicken ovalbumin upstream promoter-transcription factor II enhances invasiveness of human lung carcinoma cells
-
Navab R, Gonzalez-Santos JM, Johnston MR, Liu J, Brodt P, et al. (2004) Expression of chicken ovalbumin upstream promoter-transcription factor II enhances invasiveness of human lung carcinoma cells. Cancer Res 64: 5097-5105.
-
(2004)
Cancer Res
, vol.64
, pp. 5097-5105
-
-
Navab, R.1
Gonzalez-Santos, J.M.2
Johnston, M.R.3
Liu, J.4
Brodt, P.5
-
46
-
-
20344383528
-
Microarray analysis of endometrial carcinomas and mixed mullerian tumors reveals distinct gene expression profiles associated with different histologic types of uterine cancer
-
Maxwell GL, Chandramouli GV, Dainty L, Litzi TJ, Berchuck A, et al. (2005) Microarray analysis of endometrial carcinomas and mixed mullerian tumors reveals distinct gene expression profiles associated with different histologic types of uterine cancer. Clin Cancer Res 11: 4056-4066.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4056-4066
-
-
Maxwell, G.L.1
Chandramouli, G.V.2
Dainty, L.3
Litzi, T.J.4
Berchuck, A.5
-
47
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, et al. (2006) Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 66: 2815-2825.
-
(2006)
Cancer Res
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
-
48
-
-
58849119933
-
Role of SP transcription factors in hormone-dependent modulation of genes in MCF-7 breast cancer cells: Microarray and RNA interference studies
-
Wu F, Ivanov I, Xu R, Safe S (2009) Role of SP transcription factors in hormone-dependent modulation of genes in MCF-7 breast cancer cells: microarray and RNA interference studies. J Mol Endocrinol 42: 19-33.
-
(2009)
J Mol Endocrinol
, vol.42
, pp. 19-33
-
-
Wu, F.1
Ivanov, I.2
Xu, R.3
Safe, S.4
|