Formation and closure of microchannels in skin following microporation

Pharmaceutical Research

Volumn 28, Issue 1, 2011, Pages 82-94

  Kalluri, Haripriya ^a   Banga, Ajay K ^a  

^a MERCER UNIVERSITY   (United States)

Author keywords

microchannels; microneedles; microporation; pore closure; transdermal delivery

Indexed keywords

CALCEIN; MALTOSE; METHYLENE BLUE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GEOMETRY; HISTOLOGY; IMAGE ANALYSIS; MALE; MICROPORATION; NEEDLE; NONHUMAN; NUCLEAR PORE; PERMEABILITY BARRIER; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SKIN PENETRATION; SKIN WATER LOSS; STRATUM CORNEUM;

ANIMALS; DRUG DELIVERY SYSTEMS; INJECTIONS, INTRADERMAL; KINETICS; MALE; MALTOSE; MICROINJECTIONS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; NEEDLES; PERMEABILITY; RATS; RATS, HAIRLESS; SKIN; SOLUBILITY; SURFACE PROPERTIES; TIME FACTORS;

EID: 78651231668     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0122-x     Document Type: Article

References (38)

1. AK Banga 2009 Microporation applications for enhancing drug delivery Expert Opin Drug Deliv 6 343 54 1:CAS:528:DC%2BD1MXkvFCisr8%3D 10.1517/17425240902841935 19348604
2. CS Kolli AK Banga 2008 Characterization of solid maltose microneedles and their use for transdermal delivery Pharm Res 25 104 13 1:CAS:528: DC%2BD1cXkslSntg%3D%3D 10.1007/s11095-007-9350-0 17597381
3. M Cormier B Johnson M Ameri K Nyam L Libiran DD Zhang, et al. 2004 Transdermal delivery of desmopressin using a coated microneedle array patch system J Control Release 97 503 11 1:CAS:528:DC%2BD2cXkvF2itLs%3D 15212882
4. W Martanto SP Davis NR Holiday J Wang HS Gill MR Prausnitz 2004 Transdermal delivery of insulin using microneedles in vivo Pharm Res 21 947 52 1:CAS:528:DC%2BD2cXktlykurw%3D 10.1023/B:PHAM.0000029282.44140.2e 15212158 (Pubitemid 38870143)
5. SP Davis W Martanto MG Allen MR Prausnitz 2005 Hollow metal microneedles for insulin delivery to diabetic rats IEEE Trans Biomed Eng 52 909 15 10.1109/TBME.2005.845240 15887540 (Pubitemid 40675490)
6. JH Park MG Allen MR Prausnitz 2005 Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery J Control Release 104 51 66 1:CAS:528:DC%2BD2MXjvVClsLg%3D 10.1016/j.jconrel.2005.02.002 15866334 (Pubitemid 40615235)
7. JA Matriano M Cormier J Johnson WA Young M Buttery K Nyam, et al. 2002 Macroflux microprojection array patch technology: a new and efficient approach for intracutaneous immunization Pharm Res 19 63 70 1:CAS:528: DC%2BD38XhtVSmsbg%3D 10.1023/A:1013607400040 11837701 (Pubitemid 34075108)
8. W Lin M Cormier A Samiee A Griffin B Johnson CL Teng, et al. 2001 Transdermal delivery of antisense oligonucleotides with microprojection patch (Macroflux) technology Pharm Res 18 1789 93 1:CAS:528:DC%2BD38XhvVamsQ%3D%3D 10.1023/A:1013395102049 11785702 (Pubitemid 34020438)
9. F Chabri K Bouris T Jones D Barrow A Hann C Allender, et al. 2004 Microfabricated silicon microneedles for nonviral cutaneous gene delivery Br J Dermatol 150 869 77 1:CAS:528:DC%2BD2cXlt1Kgurk%3D 10.1111/j.1365-2133.2004. 05921.x 15149498 (Pubitemid 38903518)
10. DV McAllister PM Wang SP Davis JH Park PJ Canatella MG Allen, et al. 2003 Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies Proc Natl Acad Sci USA 100 13755 60 1:CAS:528:DC%2BD3sXpsFGisrw%3D 10.1073/pnas.2331316100 14623977 (Pubitemid 37499139)
11. G Li A Badkar S Nema CS Kolli AK Banga 2009 In vitro transdermal delivery of therapeutic antibodies using maltose microneedles Int J Pharm 368 109 15 1:CAS:528:DC%2BD1MXhsFertrY%3D 10.1016/j.ijpharm.2008.10.008 18996461
12. G Widera J Johnson L Kim L Libiran K Nyam PE Daddona, et al. 2006 Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system Vaccine 24 1653 64 1:CAS:528:DC%2BD28XhsF2gsr4%3D 10.1016/j.vaccine.2005.09.049 16246466 (Pubitemid 43238242)
13. MAL Teo C Shearwood KC Ng J Lu S Moochhala 2005 In vitro and in vivo characterization of MEMS microneedles Biomed Microdevices 7 47 52 10.1007/s10544-005-6171-y 15834520 (Pubitemid 40613130)
14. PM Wang M Cornwell J Hill MR Prausnitz 2006 Precise microinjection into skin using hollow microneedles J Invest Dermatol 126 1080 7 1:CAS:528: DC%2BD28XjsFSqsr4%3D 10.1038/sj.jid.5700150 16484988
15. Kalluri H, Banga AK. Microneedles and transdermal drug delivery. Journal of drug delivery science and technology. In print: 2009.
16. Teo AL, Shearwood C, Ng KC, Lu J, Moochhala S. Transdermal microneedles for drug delivery applications. Mater Sci Eng B. 2006.
17. JH Oh HH Park KY Do M Han DH Hyun CG Kim, et al. 2008 Influence of the delivery systems using a microneedle array on the permeation of a hydrophilic molecule, calcein Eur J Pharm Biopharm 69 1040 5 1:CAS:528:DC%2BD1cXpt1GqsLY%3D 10.1016/j.ejpb.2008.02.009 18411045
18. JA Mikszta JB Alarcon JM Brittingham DE Sutter RJ Pettis NG Harvey 2002 Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery Nat Med 8 415 9 1:CAS:528: DC%2BD38XivVGls7k%3D 10.1038/nm0402-415 11927950 (Pubitemid 34407039)
19. GK Menon KR Feingold PM Elias 1992 Lamellar body secretory response to barrier disruption J Invest Dermatol 98 279 89 1:STN:280:DyaK387osFanug%3D%3D 10.1111/1523-1747.ep12497866 1545137
20. PM Elias 1983 Epidermal lipids, barrier function, and desquamation J Invest Dermatol 80 Suppl 44s 9 1:STN:280:DC%2BC3czkt12jsA%3D%3D 10.1038/jid.1983.12
21. B Al-Qallaf DB Das 2009 Optimizing microneedle arrays for transdermal drug delivery: extension to non-square distribution of microneedles J Drug Target 17 108 22 1:CAS:528:DC%2BD1MXitlWqug%3D%3D 10.1080/10611860802472370 19016071
22. Gupta J. Microneedles for transdermal drug delivery in human subjects, School of Chemical and Biomolecular Engineering, Vol. Ph.D. Dissertation, Georgia Institute of Technology, Atlanta; 2009. p. 198.
23. Gupta J, Andrews S, Gill HS, Prausnitz MR. Kinetics of skin resealing after insertion of microneedles in human subjects. New York: Controlled Release Society Annual Meeting; 2008.
24. MI Haq E Smith DN John M Kalavala C Edwards A Anstey, et al. 2009 Clinical administration of microneedles: skin puncture, pain and sensation Biomed Microdevices 11 35 47 1:STN:280:DC%2BD1M7hvVKntA%3D%3D 10.1007/s10544-008-9208-1 18663579
25. B Al-Qallaf DB Das 2009 Optimizing microneedle arrays to increase skin permeability for transdermal drug delivery Ann N Y Acad Sci 1161 83 94 10.1111/j.1749-6632.2009.04083.x 19426308
26. G Grubauer PM Elias KR Feingold 1989 Transepidermal water loss: the signal for recovery of barrier structure and function J Lipid Res 30 323 33 1:CAS:528:DyaL1MXhslSqsLo%3D 2723540
27. SK Ahn SJ Jiang SM Hwang EH Choi JS Lee SH Lee 2001 Functional and structural changes of the epidermal barrier induced by various types of insults in hairless mice Arch Dermatol Res 293 308 18 1:STN:280:DC%2BD38%2FisFCksA%3D%3D 10.1007/s004030100226 11480591 (Pubitemid 32661499)
28. L Kennish B Reidenberg 2005 A review of the effect of occlusive dressings on lamellar bodies in the stratum corneum and relevance to transdermal absorption Dermatol Online J 11 7 16409903
29. GK Menon PM Elias KR Feingold 1994 Integrity of the permeability barrier is crucial for maintenance of the epidermal calcium gradient Br J Dermatol 130 139 47 1:CAS:528:DyaK2cXivFGitr4%3D 10.1111/j.1365-2133.1994.tb02892.x 8123567 (Pubitemid 24204607)
30. GK Menon S Grayson PM Elias 1985 Ionic calcium reservoirs in mammalian epidermis: ultrastructural localization by ion-capture cytochemistry J Invest Dermatol 84 508 12 1:CAS:528:DyaL2MXitFyrsLo%3D 10.1111/1523-1747.ep12273485 3998499
31. M Taljebini R Warren M Mao-Oiang E Lane PM Elias KR Feingold 1996 Cutaneous permeability barrier repair following various types of insults: kinetics and effects of occlusion Skin Pharmacol 9 111 9 1:STN:280: DyaK28zmt1Crsw%3D%3D 10.1159/000211406 8722605
32. S Jiang SW Koo SH Lee 1998 The morphologic changes in lamellar bodies and intercorneocyte lipids after tape stripping and occlusion with a water vapor-impermeable membrane Arch Dermatol Res 290 145 51 1:STN:280: DyaK1c3hvFWrsw%3D%3D 10.1007/s004030050280 9558490 (Pubitemid 28143367)
33. M Mao-Qiang T Mauro G Bench R Warren PM Elias KR Feingold 1997 Calcium and potassium inhibit barrier recovery after disruption, independent of the type of insult in hairless mice Exp Dermatol 6 36 40 1:CAS:528:DyaK2sXit1aqsrw%3D 10.1111/j.1600-0625.1997.tb00143.x 9067705 (Pubitemid 27132637)
34. SH Lee PM Elias E Proksch GK Menon M Mao-Quiang KR Feingold 1992 Calcium and potassium are important regulators of barrier homeostasis in murine epidermis J Clin Invest 89 530 8 1:CAS:528:DyaK38XhsV2jsrg%3D 10.1172/JCI115617 1737844
35. SH Lee PM Elias KR Feingold T Mauro 1994 A role for ions in barrier recovery after acute perturbation J Invest Dermatol 102 976 9 1:CAS:528:DyaK2cXmsFagsrY%3D 10.1111/1523-1747.ep12384225 8006464
36. Hachem JP, Crumrine D, Fluhr J, Brown BE, Feingold KR, Elias PM. pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion. J Invest Dermatol. 2003;121(2):345-53.
37. Fluhr JW, Mao-Qiang M, Brown BE, Hachem JP, Moskowitz DG, Demerjian M, Haftek M, Serre G, Crumrine D, Mauro TM, Elias PM, Feingold KR. Functional consequences of a neutral pH in neonatal rat stratum corneum. J Invest Dermatol. 2004;123(1):140-50.
38. Hachem JP, Man MQ, Crumrine D, Uchida Y, Brown BE, Rogiers V, Roseeuw D, Feingold KR, Elias PM. Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity. J Invest Dermatol. 2005;125(3):510-20.