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Volumn 6, Issue 4, 2009, Pages 343-354

Microporation applications for enhancing drug delivery

Author keywords

Laser ablation; Microneedles; Microporation; Radiofrequency ablation; Thermal ablation; Transdermal delivery

Indexed keywords

ALBUMIN; CHONDROITIN SULFATE; DEXTRIN; ERYTHROPOIETIN; MALTOSE; POLYMER;

EID: 67649096926     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425240902841935     Document Type: Review
Times cited : (133)

References (87)
  • 1
    • 17844389701 scopus 로고    scopus 로고
    • Physical enhancement of transdermal drug application: Is delivery technology keeping up with pharmaceutical development?
    • Cross SE, Roberts MS. Physical enhancement of transdermal drug application: is delivery technology keeping up with pharmaceutical development? Curr Drug Deliv 2004;1:81-92
    • (2004) Curr Drug Deliv , vol.1 , pp. 81-92
    • Cross, S.E.1    Roberts, M.S.2
  • 2
    • 33745844749 scopus 로고    scopus 로고
    • Current developments using emerging transdermal technologies in physical enhancement methods
    • DOI 10.2174/156720106777731091
    • Nanda A, Nanda S, Ghilzai NM. Current developments using emerging transdermal technologies in physical enhancement methods. Curr Drug Deliv 2006;3:233-242 (Pubitemid 44031622)
    • (2006) Current Drug Delivery , vol.3 , Issue.3 , pp. 233-242
    • Nanda, A.1    Nanda, S.2    Ghilzai, N.M.K.3
  • 3
    • 33847205770 scopus 로고    scopus 로고
    • New technologies to allow transdermal delivery of therapeutic proteins and small water-soluble drugs
    • DOI 10.2165/00137696-200604040-00005
    • Banga AK. New technologies to allow transdermal delivery of therapeutic proteins and small water-soluble drugs. Am J Drug Deliv 2006;4:221-230 (Pubitemid 46307153)
    • (2006) American Journal of Drug Delivery , vol.4 , Issue.4 , pp. 221-230
    • Banga, A.K.1
  • 5
    • 0034934052 scopus 로고    scopus 로고
    • Overcoming skin's barrier: The search for effective and user-friendly drug delivery
    • DOI 10.1089/152091501300209606
    • Prausnitz MR. Overcoming skin's barrier: the search for effective and user-friendly drug delivery. Diabetes Technol Ther 2001;3:233-236 (Pubitemid 32651959)
    • (2001) Diabetes Technology and Therapeutics , vol.3 , Issue.2 , pp. 233-236
    • Prausnitz, M.R.1
  • 9
    • 39749199632 scopus 로고    scopus 로고
    • Painless drug delivery through microneedle-based transdermal patches featuring active infusion
    • DOI 10.1109/TBME.2007.906492
    • Roxhed N, Samel B, Nordquist L, et al. Painless drug delivery through microneedle-based transdermal patches featuring active infusion. IEEE Trans Biomed Eng 2008;55:1063-1071 • This paper presents a microneedle patch integrated with a drug reservoir and reports that microneedle insertion in human subjects was not painful. (Pubitemid 351301214)
    • (2008) IEEE Transactions on Biomedical Engineering , vol.55 , Issue.3 , pp. 1063-1071
    • Roxhed, N.1    Samel, B.2    Nordquist, L.3    Griss, P.4    Stemme, G.5
  • 10
    • 41149125953 scopus 로고    scopus 로고
    • Microneedles permit transdermal delivery of a skin-impermeant medication to humans
    • Wermeling DP, Banks SL, Hudson DA, et al. Microneedles permit transdermal delivery of a skin-impermeant medication to humans. Proc Natl Acad Sci USA 2008;105:2058-2063
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2058-2063
    • Wermeling, D.P.1    Banks, S.L.2    Hudson, D.A.3
  • 11
    • 50449085359 scopus 로고    scopus 로고
    • In vivo assessment of safety of microneedle arrays in human skin
    • Bal SM, Caussin J, Pavel S, et al. In vivo assessment of safety of microneedle arrays in human skin. Eur J Pharm Sci 2008;35:193-202
    • (2008) Eur J Pharm Sci , vol.35 , pp. 193-202
    • Bal, S.M.1    Caussin, J.2    Pavel, S.3
  • 12
    • 44649083690 scopus 로고    scopus 로고
    • Flux across microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro
    • Banks SL, Pinninti RR, Gill HS, et al. Flux across microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro. Pharm Res 2008;25:1677-1685
    • (2008) Pharm Res , vol.25 , pp. 1677-1685
    • Banks, S.L.1    Pinninti, R.R.2    Gill, H.S.3
  • 13
    • 58949100880 scopus 로고    scopus 로고
    • In vitro transdermal delivery of therapeutic antibodies using maltose microneedles
    • Li G, Badkar A, Nema S, et al. In vitro transdermal delivery of therapeutic antibodies using maltose microneedles. Int J Pharm 2009;368:109-115
    • (2009) Int J Pharm , vol.368 , pp. 109-115
    • Li, G.1    Badkar, A.2    Nema, S.3
  • 17
    • 34249872741 scopus 로고    scopus 로고
    • Novel microneedle patches for active insulin delivery are efficient in maintaining glycaemic control: An initial comparison with subcutaneous administration
    • DOI 10.1007/s11095-007-9256-x
    • Nordquist L, Roxhed N, Griss P, et al. Novel microneedle patches for active insulin delivery are efficient in maintaining glycaemic control: an initial comparison with subcutaneous administration. Pharm Res 2007;24:1381-1388 (Pubitemid 46870597)
    • (2007) Pharmaceutical Research , vol.24 , Issue.7 , pp. 1381-1388
    • Nordquist, L.1    Roxhed, N.2    Griss, P.3    Stemme, G.4
  • 19
    • 32544446281 scopus 로고    scopus 로고
    • Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system
    • DOI 10.1016/j.vaccine.2005.09.049, PII S0264410X05010157
    • Widera G, Johnson J, Kim L, et al. Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system. Vaccine 2006;24:1653-1664 (Pubitemid 43238242)
    • (2006) Vaccine , vol.24 , Issue.10 , pp. 1653-1664
    • Widera, G.1    Johnson, J.2    Kim, L.3    Libiran, L.4    Nyam, K.5    Daddona, P.E.6    Cormier, M.7
  • 24
    • 1542358759 scopus 로고    scopus 로고
    • Microneedles for transdermal drug delivery
    • DOI 10.1016/j.addr.2003.10.023, PII S0169409X03002394
    • Prausnitz MR. Microneedles for transdermal drug delivery. Adv Drug Deliv Rev 2004;56:581-587 (Pubitemid 38326934)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.5 , pp. 581-587
    • Prausnitz, M.R.1
  • 27
    • 57849157314 scopus 로고    scopus 로고
    • Microneedle mediated delivery of nanoparticles into human skin
    • • This study investigates the delivery of nanoparticles into/across microporated skin and the various factors associated with it
    • Coulman SA, Anstey A, Gateley C, et al. Microneedle mediated delivery of nanoparticles into human skin. Int J Pharm 2009;366:190-200 • This study investigates the delivery of nanoparticles into/across microporated skin and the various factors associated with it.
    • (2009) Int J Pharm , vol.366 , pp. 190-200
    • Coulman, S.A.1    Anstey, A.2    Gateley, C.3
  • 28
    • 34249875157 scopus 로고    scopus 로고
    • Coating formulations for microneedles
    • DOI 10.1007/s11095-007-9286-4
    • Gill HS, Prausnitz MR. Coating formulations for microneedles. Pharm Res 2007;24:1369-1380 (Pubitemid 46870599)
    • (2007) Pharmaceutical Research , vol.24 , Issue.7 , pp. 1369-1380
    • Gill, H.S.1    Prausnitz, M.R.2
  • 29
    • 33846492454 scopus 로고    scopus 로고
    • Coated microneedles for transdermal delivery
    • DOI 10.1016/j.jconrel.2006.10.017, PII S0168365906005839
    • Gill HS, Prausnitz MR. Coated microneedles for transdermal delivery. J Control Release 2007;117:227-237 • A good study which investigates a novel coating technique for microneedles with application to a wide range of therapeutic moieties. (Pubitemid 46161873)
    • (2007) Journal of Controlled Release , vol.117 , Issue.2 , pp. 227-237
    • Gill, H.S.1    Prausnitz, M.R.2
  • 31
    • 4344679112 scopus 로고    scopus 로고
    • In-plane single-crystal-silicon microneedles for minimally invasive microfluid systems
    • Paik S, Byun S, Lim J, et al. In-plane single-crystal-silicon microneedles for minimally invasive microfluid systems. Sens Actuators A 2004;114:276-284
    • (2004) Sens Actuators A , vol.114 , pp. 276-284
    • Paik, S.1    Byun, S.2    Lim, J.3
  • 32
    • 4344666269 scopus 로고    scopus 로고
    • Microneedle array for transdermal biological fluid extraction and in situ analysis
    • Mukerjee EV, Collins SD, Isseroff RR, et al. Microneedle array for transdermal biological fluid extraction and in situ analysis. Sens Actuators A 2004;114:267-275
    • (2004) Sens Actuators A , vol.114 , pp. 267-275
    • Mukerjee, E.V.1    Collins, S.D.2    Isseroff, R.R.3
  • 33
    • 67649087795 scopus 로고    scopus 로고
    • Available from: Accessed February 2009
    • Available from: http://www.halozyme.com [Accessed February 2009]
  • 34
    • 33646148967 scopus 로고    scopus 로고
    • Precise microinjection into skin using hollow microneedles
    • Wang PM, Cornwell M, Hill J, et al. Precise microinjection into skin using hollow microneedles. J Invest Dermatol 2006;126:1080-1087
    • (2006) J Invest Dermatol , vol.126 , pp. 1080-1087
    • Wang, P.M.1    Cornwell, M.2    Hill, J.3
  • 36
    • 33646709695 scopus 로고    scopus 로고
    • Mechanism of fluid infusion during microneedle insertion and retraction
    • DOI 10.1016/j.jconrel.2006.02.017, PII S0168365906001076
    • Martanto W, Moore JS, Couse T, et al. Mechanism of fluid infusion during microneedle insertion and retraction. J Control Release 2006;112:357-361 (Pubitemid 43737149)
    • (2006) Journal of Controlled Release , vol.112 , Issue.3 , pp. 357-361
    • Martanto, W.1    Moore, J.S.2    Couse, T.3    Prausnitz, M.R.4
  • 37
    • 40349099997 scopus 로고    scopus 로고
    • Membrane-sealed hollow microneedles and related administration schemes for transdermal drug delivery
    • DOI 10.1007/s10544-007-9133-8
    • Roxhed N, Griss P, Stemme G. Membrane-sealed hollow microneedles and related administration schemes for transdermal drug delivery. Biomed Microdevices 2008;10:271-279 (Pubitemid 351337929)
    • (2008) Biomedical Microdevices , vol.10 , Issue.2 , pp. 271-279
    • Roxhed, N.1    Griss, P.2    Stemme, G.3
  • 39
    • 0037462995 scopus 로고    scopus 로고
    • Microfabricated drug delivery systems: From particles to pores
    • DOI 10.1016/S0169-409X(02)00227-2
    • Tao SL, Desai TA. Microfabricated drug delivery systems: from particles to pores. Adv Drug Deliv Rev 2003;55:315-328 (Pubitemid 36293790)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.3 , pp. 315-328
    • Tao, S.L.1    Desai, T.A.2
  • 40
    • 27844509988 scopus 로고    scopus 로고
    • Microfabricated drug delivery devices
    • DOI 10.1016/j.ijpharm.2005.09.022, PII S0378517305006460
    • Hilt JZ, Peppas NA. Microfabricated drug delivery devices. Int J Pharm 2005;306:15-23 (Pubitemid 41643137)
    • (2005) International Journal of Pharmaceutics , vol.306 , Issue.1-2 , pp. 15-23
    • Hilt, J.Z.1    Peppas, N.A.2
  • 41
    • 48749105332 scopus 로고    scopus 로고
    • Microneedle-based drug delivery: Studies on delivery parameters and biocompatibility
    • Wu Y, Qiu Y, Zhang S, et al. Microneedle-based drug delivery: studies on delivery parameters and biocompatibility. Biomed Microdevices 2008;10:601-610
    • (2008) Biomed Microdevices , vol.10 , pp. 601-610
    • Wu, Y.1    Qiu, Y.2    Zhang, S.3
  • 42
    • 33845648163 scopus 로고    scopus 로고
    • Microneedles and other physical methods for overcoming the stratum corneum barrier for cutaneous gene therapy
    • Coulman S, Allender C, Birchall J. Microneedles and other physical methods for overcoming the stratum corneum barrier for cutaneous gene therapy. Crit Rev Ther Drug Carrier Syst 2006;23:205-258 (Pubitemid 44950092)
    • (2006) Critical Reviews in Therapeutic Drug Carrier Systems , vol.23 , Issue.3 , pp. 205-258
    • Coulman, S.1    Allender, C.2    Birchall, J.3
  • 43
    • 2942722611 scopus 로고    scopus 로고
    • A novel polymer microneedle arrays and PDMS micromolding technique
    • Kuo S, Chou Y. A novel polymer microneedle arrays and PDMS micromolding technique. Tamkang J Sci Engg 2004;7:95-98
    • (2004) Tamkang J Sci Engg , vol.7 , pp. 95-98
    • Kuo, S.1    Chou, Y.2
  • 45
    • 38049146196 scopus 로고    scopus 로고
    • Characterization of solid maltose microneedles and their use for transdermal delivery
    • • A study which investigates the use of soluble maltose microneedles for potentially safe and effective drug delivery
    • Kolli CS, Banga AK. Characterization of solid maltose microneedles and their use for transdermal delivery. Pharm Res 2008;25:104-113 • A study which investigates the use of soluble maltose microneedles for potentially safe and effective drug delivery.
    • (2008) Pharm Res , vol.25 , pp. 104-113
    • Kolli, C.S.1    Banga, A.K.2
  • 46
    • 38349175137 scopus 로고    scopus 로고
    • Synergistic effect of iontophoresis and soluble microneedles for transdermal delivery of methotrexate
    • Vemulapalli V, Yang Y, Friden PM, et al. Synergistic effect of iontophoresis and soluble microneedles for transdermal delivery of methotrexate. J Pharm Pharmacol 2008;60:27-33
    • (2008) J Pharm Pharmacol , vol.60 , pp. 27-33
    • Vemulapalli, V.1    Yang, Y.2    Friden, P.M.3
  • 47
    • 33746809493 scopus 로고    scopus 로고
    • Self-dissolving microneedles for the percutaneous absorption of EPO in mice
    • DOI 10.1080/10611860600785080, PII X4H5102325593211
    • Ito Y, Yoshimitsu J, Shiroyama K, et al. Self-dissolving microneedles for the percutaneous absorption of EPO in mice. J Drug Target 2006;14:255-261 (Pubitemid 44173291)
    • (2006) Journal of Drug Targeting , vol.14 , Issue.5 , pp. 255-261
    • Ito, Y.1    Yoshimitsu, J.-I.2    Shiroyama, K.3    Sugioka, N.4    Takada, K.5
  • 48
    • 40049112272 scopus 로고    scopus 로고
    • Dissolving microneedles for transdermal drug delivery
    • Lee JW, Park JH, Prausnitz MR. Dissolving microneedles for transdermal drug delivery. Biomaterials 2008;29:2113-2124
    • (2008) Biomaterials , vol.29 , pp. 2113-2124
    • Lee, J.W.1    Park, J.H.2    Prausnitz, M.R.3
  • 49
    • 18144410179 scopus 로고    scopus 로고
    • Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery
    • DOI 10.1016/j.jconrel.2005.02.002
    • Park JH, Allen MG, Prausnitz MR. Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery. J Control Release 2005;104:51-66 (Pubitemid 40615235)
    • (2005) Journal of Controlled Release , vol.104 , Issue.1 , pp. 51-66
    • Park, J.-H.1    Allen, M.G.2    Prausnitz, M.R.3
  • 50
    • 33646882359 scopus 로고    scopus 로고
    • Polymer microneedles for controlled-release drug delivery
    • DOI 10.1007/s11095-006-0028-9
    • Park JH, Allen MG, Prausnitz MR. Polymer microneedles for controlled-release drug delivery. Pharm Res 2006;23:1008-1019 (Pubitemid 43781409)
    • (2006) Pharmaceutical Research , vol.23 , Issue.5 , pp. 1008-1019
    • Park, J.-H.1    Allen, M.G.2    Prausnitz, M.R.3
  • 51
    • 67649101300 scopus 로고    scopus 로고
    • Available from: Accessed February 2009
    • Available from: http://www.zosanopharma.com [Accessed February 2009]
  • 52
    • 67649087793 scopus 로고    scopus 로고
    • Transdermal delivery: A solid microstructured transdermal system (sMTS) for systemic delivery of salts and proteins
    • Hansen K, Haldin B. Transdermal delivery: a solid microstructured transdermal system (sMTS) for systemic delivery of salts and proteins. Drug Deliv Technol 2008;8:38-42
    • (2008) Drug Deliv Technol , vol.8 , pp. 38-42
    • Hansen, K.1    Haldin, B.2
  • 55
    • 67649117584 scopus 로고    scopus 로고
    • Microneedle penetration and injection past the stratum corneum in humans
    • Sivamani RK, Stoeber B, Liepmann D, et al. Microneedle penetration and injection past the stratum corneum in humans. J Dermatolog Treat 2008;1-4
    • (2008) J Dermatolog Treat , pp. 1-4
    • Sivamani, R.K.1    Stoeber, B.2    Liepmann, D.3
  • 56
    • 18144406466 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of MEMS microneedles
    • Teo MA, Shearwood C, Ng KC, et al. In vitro and in vivo characterization of MEMS microneedles. Biomed Microdevices 2005;7:47-52
    • (2005) Biomed Microdevices , vol.7 , pp. 47-52
    • Teo, M.A.1    Shearwood, C.2    Ng, K.C.3
  • 57
    • 2942716734 scopus 로고    scopus 로고
    • Insertion of microneedles into skin: Measurement and prediction of insertion force and needle fracture force
    • DOI 10.1016/j.jbiomech.2003.12.010, PII S0021929003004731
    • Davis SP, Landis BJ, Adams ZH, et al. Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force. J Biomech 2004;37:1155-1163 • A well designed study which investigates the various parameters/forces associated with insertion of microneedles into skin. (Pubitemid 38798369)
    • (2004) Journal of Biomechanics , vol.37 , Issue.8 , pp. 1155-1163
    • Davis, S.P.1    Landis, B.J.2    Adams, Z.H.3    Allen, M.G.4    Prausnitz, M.R.5
  • 58
    • 42749084964 scopus 로고    scopus 로고
    • Improved piercing of microneedle arrays in dermatomed human skin by an impact insertion method
    • Verbaan FJ, Bal SM, van den Berg DJ, et al. Improved piercing of microneedle arrays in dermatomed human skin by an impact insertion method. J Control Release 2008;128:80-88
    • (2008) J Control Release , vol.128 , pp. 80-88
    • Verbaan, F.J.1    Bal, S.M.2    Van Den Berg, D.J.3
  • 59
    • 48149083798 scopus 로고    scopus 로고
    • Influence of the delivery systems using a microneedle array on the permeation of a hydrophilic molecule, calcein
    • Oh JH, Park HH, Do KY, et al. Influence of the delivery systems using a microneedle array on the permeation of a hydrophilic molecule, calcein. Eur J Pharm Biopharm 2008;69:1040-1045
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 1040-1045
    • Oh, J.H.1    Park, H.H.2    Do, K.Y.3
  • 60
    • 18044394948 scopus 로고    scopus 로고
    • Transdermal delivery of human growth hormone through RF-microchannels
    • DOI 10.1007/s11095-005-2498-6
    • Levin G, Gershonowitz A, Sacks H, et al. Transdermal delivery of human growth hormone through RF-microchannels. Pharm Res 2005;22:550-555 • This paper uses a novel radio-frequency ablation approach to achieve skin microporation and reports delivery of a protein, human growth hormone, with a bioavailability as high as 75%, relative to subcutaneous injection. (Pubitemid 40603252)
    • (2005) Pharmaceutical Research , vol.22 , Issue.4 , pp. 550-555
    • Levin, G.1    Gershonowitz, A.2    Sacks, H.3    Stern, M.4    Sherman, A.5    Rudaev, S.6    Zivin, I.7    Phillip, M.8
  • 63
    • 0036099243 scopus 로고    scopus 로고
    • Occlusion vs. skin barrier function
    • DOI 10.1046/j.0909-752x.2001.10311.x
    • Zhai H, Maibach HI. Occlusion vs. skin barrier function. Skin Res Technol 2002;8:1-6 (Pubitemid 34555457)
    • (2002) Skin Research and Technology , vol.8 , Issue.1 , pp. 1-6
    • Zhai, H.1    Maibach, H.I.2
  • 64
    • 29844432699 scopus 로고    scopus 로고
    • A review of the effect of occlusive dressings on lamellar bodies in the stratum corneum and relevance to transdermal absorption
    • Kennish L, Reidenberg B. A review of the effect of occlusive dressings on lamellar bodies in the stratum corneum and relevance to transdermal absorption. Dermatol Online J 2005;11:7 (Pubitemid 43034783)
    • (2005) Dermatology Online Journal , vol.11 , Issue.3 , pp. 7
    • Kennish, L.1    Reidenberg, B.2
  • 65
    • 44749093959 scopus 로고    scopus 로고
    • The effect of heat on skin permeability
    • Park JH, Lee JW, Kim YC, et al. The effect of heat on skin permeability. Int J Pharm 2008;359:94-103
    • (2008) Int J Pharm , vol.359 , pp. 94-103
    • Park, J.H.1    Lee, J.W.2    Kim, Y.C.3
  • 66
    • 67649128204 scopus 로고    scopus 로고
    • Available from: Accessed February 2009
    • Available from: http://www.alteatherapeutics.com [Accessed February 2009]
  • 67
    • 34249949043 scopus 로고    scopus 로고
    • Transdermal delivery of interferon alpha-2b using microporation and iontophoresis in hairless rats
    • DOI 10.1007/s11095-007-9308-2
    • Badkar AV, Smith AM, Eppstein JA, et al. Transdermal delivery of interferon alpha-2B using microporation and iontophoresis in hairless rats. Pharm Res 2007;24:1389-1395 (Pubitemid 46876496)
    • (2007) Pharmaceutical Research , vol.24 , Issue.7 , pp. 1389-1395
    • Badkar, A.V.1    Smith, A.M.2    Eppstein, J.A.3    Banga, A.K.4
  • 68
    • 0037322494 scopus 로고    scopus 로고
    • Enabling topical immunization via microporation: A novel method for pain-free and needle-free delivery of adenovirus-based vaccines
    • DOI 10.1038/sj.gt.3301886
    • Bramson J, Dayball K, Evelegh C, et al. Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines. Gene Ther 2003;10:251-260 (Pubitemid 36204414)
    • (2003) Gene Therapy , vol.10 , Issue.3 , pp. 251-260
    • Bramson, J.1    Dayball, K.2    Evelegh, C.3    Wan, Y.H.4    Page, D.5    Smith, A.6
  • 69
    • 0033086369 scopus 로고    scopus 로고
    • Fluorescein kinetics in interstitial fluid harvested from diabetic skin during fluorescein angiography: Implications for glucose monitoring
    • Smith A, Yang D, Delcher H, et al. Fluorescein kinetics in interstitial fluid harvested from diabetic skin during fluorescein angiography: implications for glucose monitoring. Diabetes Technol Ther 1999;1:21-27
    • (1999) Diabetes Technol Ther , vol.1 , pp. 21-27
    • Smith, A.1    Yang, D.2    Delcher, H.3
  • 70
    • 33645033375 scopus 로고    scopus 로고
    • Cutaneous gene expression of plasmid DNA in excised human skin following delivery via microchannels created by radio frequency ablation
    • Birchall J, Coulman S, Anstey A, et al. Cutaneous gene expression of plasmid DNA in excised human skin following delivery via microchannels created by radio frequency ablation. Int J Pharm 2006;312:15-23
    • (2006) Int J Pharm , vol.312 , pp. 15-23
    • Birchall, J.1    Coulman, S.2    Anstey, A.3
  • 71
    • 0037472111 scopus 로고    scopus 로고
    • Radiofrequency-driven skin microchanneling as a new way for electrically assisted transdermal delivery of hydrophilic drugs
    • DOI 10.1016/S0168-3659(03)00123-8
    • Sintov AC, Krymberk I, Daniel D, et al. Radiofrequency-driven skin microchanneling as a new way for electrically assisted transdermal delivery of hydrophilic drugs. J Control Release 2003;89:311-320 (Pubitemid 36507024)
    • (2003) Journal of Controlled Release , vol.89 , Issue.2 , pp. 311-320
    • Sintov, A.C.1    Krymberk, I.2    Daniel, D.3    Hannan, T.4    Sohn, Z.5    Levin, G.6
  • 72
    • 67649132358 scopus 로고    scopus 로고
    • Available from: Accessed February 2009
    • Available from: http://www.transpharmamedical.com; [Accessed February 2009]
  • 73
    • 67649116154 scopus 로고    scopus 로고
    • Intraepidermal Delivery: P.L.E.A.S.E., a new laser microporation technology
    • Kalia YN, Bachhav YG, Bragagna T, et al. Intraepidermal Delivery: P.L.E.A.S.E., a new laser microporation technology. Drug Deliv Technol 2008;8:26-31
    • (2008) Drug Deliv Technol , vol.8 , pp. 26-31
    • Kalia, Y.N.1    Bachhav, Y.G.2    Bragagna, T.3
  • 75
    • 0036751699 scopus 로고    scopus 로고
    • Transdermal delivery of poly-l-lysine by sonomacroporation
    • DOI 10.1016/S0301-5629(02)00571-9, PII S0301562902005719
    • Weimann LJ, Wu J. Transdermal delivery of poly-l-lysine by sonomacroporation. Ultrasound Med Biol 2002;28:1173-1180 (Pubitemid 35215094)
    • (2002) Ultrasound in Medicine and Biology , vol.28 , Issue.9 , pp. 1173-1180
    • Weimann, L.J.1    Wu, J.2
  • 76
  • 77
    • 4043119712 scopus 로고    scopus 로고
    • Enhancement of topical 5-aminolaevulinic acid delivery by erbium:YAG laser and microdermabrasion: A comparison with iontophoresis and electroporation
    • DOI 10.1111/j.1365-2133.2004.06051.x
    • Fang JY, Lee WR, Shen SC, et al. Enhancement of topical 5-aminolaevulinic acid delivery by erbium:YAG laser and microdermabrasion: a comparison with iontophoresis and electroporation. Br J Dermatol 2004;151:132-140 (Pubitemid 39061290)
    • (2004) British Journal of Dermatology , vol.151 , Issue.1 , pp. 132-140
    • Fang, J.-Y.1    Lee, W.-R.2    Shen, S.-C.3    Fang, Y.-P.4    Hu, C.-H.5
  • 78
    • 0023885550 scopus 로고
    • Iontophoretic delivery of drugs: Fundamentals, developments and biomedical applications
    • Banga AK, Chien YW. Iontophoretic delivery of drugs: fundamentals, developments and biomedical Applications. J Control Release 1988;7:1-24 (Pubitemid 18108772)
    • (1988) Journal of Controlled Release , vol.7 , Issue.1 , pp. 1-24
    • Banga, A.K.1    Chien, Y.W.2
  • 79
    • 34249907569 scopus 로고    scopus 로고
    • Theme section: Transdermal delivery of proteins
    • DOI 10.1007/s11095-007-9323-3
    • Banga AK. Theme section: transdermal delivery of proteins. Pharm Res 2007;24:1357-1359 (Pubitemid 46870603)
    • (2007) Pharmaceutical Research , vol.24 , Issue.7 , pp. 1357-1359
    • Banga, A.K.1
  • 80
    • 33847286041 scopus 로고    scopus 로고
    • Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis
    • DOI 10.1016/j.jconrel.2006.12.017, PII S0168365906007188
    • Wu XM, Todo H, Sugibayashi K. Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis. J Control Release 2007;118:189-195 (Pubitemid 46329739)
    • (2007) Journal of Controlled Release , vol.118 , Issue.2 , pp. 189-195
    • Wu, X.-M.1    Todo, H.2    Sugibayashi, K.3
  • 81
    • 46549083407 scopus 로고    scopus 로고
    • Enhancement of skin permeation of docetaxel: A novel approach combining microneedle and elastic liposomes
    • Qiu Y, Gao Y, Hu K, et al. Enhancement of skin permeation of docetaxel: a novel approach combining microneedle and elastic liposomes. J Control Release 2008;129:144-150
    • (2008) J Control Release , vol.129 , pp. 144-150
    • Qiu, Y.1    Gao, Y.2    Hu, K.3
  • 83
    • 59349105168 scopus 로고    scopus 로고
    • Skin penetration enhancement by a microneedle device (Dermaroller) in vitro: Dependency on needle size and applied formulation
    • Badran MM, Kuntsche J, Fahr A. Skin penetration enhancement by a microneedle device (Dermaroller) in vitro: dependency on needle size and applied formulation. Eur J Pharm Sci 2009;36:511-523
    • (2009) Eur J Pharm Sci , vol.36 , pp. 511-523
    • Badran, M.M.1    Kuntsche, J.2    Fahr, A.3
  • 84
    • 0034865686 scopus 로고    scopus 로고
    • Opioid overdose in a patient using a fentanyl patch during treatment with a warming blanket
    • Frolich MA, Giannotti A, Modell JH. Opioid overdose in a patient using a fentanyl patch during treatment with a warming blanket. Anesth Analg 2001;93:647-648 (Pubitemid 32783289)
    • (2001) Anesthesia and Analgesia , vol.93 , Issue.3 , pp. 647-648
    • Frolich, M.1    Giannotti, A.2    Modell, J.H.3
  • 87
    • 67649093843 scopus 로고    scopus 로고
    • Available from
    • Available from: http://www.pantec-biosolutions.com


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.