mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes

Lipids

Volumn 45, Issue 12, 2010, Pages 1089-1100

  Soliman, Ghada A ^a,b   Acosta Jaquez, Hugo A ^a   Fingar, Diane C ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b WESTERN MICHIGAN UNIVERSITY   (United States)

Author keywords

Adipocytes; Lipid metabolism; Lipolysis; mTOR; mTORC1; Rapamycin

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FATTY ACID DERIVATIVE; HORMONE SENSITIVE LIPASE; INSULIN; ISOPRENALINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PERILIPIN; RAPAMYCIN; SERINE; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; LIPID METABOLISM; LIPID STORAGE; LIPOLYSIS; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

3T3-L1 CELLS; ADIPOCYTES; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FATTY ACIDS, NONESTERIFIED; ISOPROTERENOL; LIPOLYSIS; MICE; PHOSPHORYLATION; PROTEINS; SIROLIMUS; TRIGLYCERIDES;

MURINAE;

EID: 78651067054     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-010-3488-y     Document Type: Article

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