Dietary phenolic acids attenuate multiple stages of protein glycation and high-glucose-stimulated proinflammatory IL-1β activation by interfering with chromatin remodeling and transcription in monocytes

Molecular Nutrition and Food Research

Volumn 54, Issue SUPPL. 2, 2010, Pages

  Wu, Chi Hao ^a   Yeh, Chi Tai ^b   Shih, Ping Hsiao ^a   Yen, Gow Chin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Chromatin remodeling; Hyperglycemia; Interleukin 1 ; Oxidative stress; Phenolic acid

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CINNAMIC ACID DERIVATIVE; CREBBP PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; HISTONE; HYDROXYBENZOIC ACID DERIVATIVE; IL1B PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; PHENOLIC ACID; PLASMA PROTEIN; PROTEIN KINASE C;

ARTICLE; CELL LINE; CHEMISTRY; CHROMATIN ASSEMBLY AND DISASSEMBLY; DIABETES MELLITUS; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GLYCOSYLATION; HUMAN; METABOLISM; MONOCYTE; OXIDATIVE STRESS; PROMOTER REGION; SECRETION;

BLOOD PROTEINS; CELL LINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CINNAMATES; CREB-BINDING PROTEIN; DIABETES COMPLICATIONS; DIABETES MELLITUS; GENE EXPRESSION REGULATION; GLUCOSE; GLYCOSYLATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HEMOGLOBIN A, GLYCOSYLATED; HISTONES; HUMANS; HYDROXYBENZOIC ACIDS; INTERLEUKIN-1BETA; MONOCYTES; NF-KAPPA B; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; PROTEIN KINASE C; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 78650914628     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900395     Document Type: Article

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