Inhibitory effect of vanillic acid on methylglyoxal-mediated glycation in apoptotic Neuro-2A cells

NeuroToxicology

Volumn 29, Issue 6, 2008, Pages 1016-1022

  Huang, Shang Ming ^a   Hsu, Chin Lin ^a   Chuang, Hong Chih ^a   Shih, Ping Hsiao ^a   Wu, Chi Hao ^a   Yen, Gow Chin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; CML; Diabetic neuropathy; Methylglyoxal; Neuro 2A cells; Vanillic acid

Indexed keywords

6 N CARBOXYMETHYLLYSINE; AMINOGUANIDINE; METHYLGLYOXAL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; PROTEIN P47; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; VANILLIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG EFFECT; GLYCATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

ANIMALS; ANNEXIN A5; APOPTOSIS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; GLYCOLYSIS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEUROBLASTOMA; PYRUVALDEHYDE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; VANILLIC ACID;

EID: 56249128564     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2008.07.002     Document Type: Article

References (42)

1. Abordo E.A., Minhas H.S., and Thornalley P.J. Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity. Biochem Pharmacol 58 (1999) 641-648
2. Allen D.A., Yaqoob M.M., and Harwood S.M. Mechanism of high glucose-induced apoptosis and its relationship to diabetic complications. J Nutr Biochem 16 (2005) 705-713
3. Aquino R., Morelli S., Tomaino A., Saija A., Grumetto L., Puglia C., et al. Antioxidant and photoprotective activity of a crude extract of Culcitium reflexum H. B. K. leaves and their major flavonoids. J Ethnopharmacol 79 (2002) 183-191
4. Baisier W.M., and Labuza T.P. Maillard browing kinetics in a liquid model system. J Agric Food Chem 40 (1992) 707-713
5. Barnett M.E., Madgwick D.K., and Takemoto D.J. Protein kinase C as a stress sensor. Cell Signal 19 (2007) 1820-1829
6. Bonnefont-Rousselot D. Glucose and reactive oxygen species. Curr Opin Clin Nutr Metab Care 5 (2002) 561-568
7. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
8. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 414 (2001) 813-820
9. Cameron N.E., Cotter M.A., Jack A.M., Basso M.D., and Hohman T.C. Protein kinase C effects on nerve function, perfusion, Na(+), K(+)-ATPase activity and glutathione content in diabetic rats. Diabetologia 42 (1999) 1120-1130
10. Chan W.H., Wu H.J., and Shiao N.H. Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3, and p21-activated kinase 2. J Cell Biochem 100 (2007) 1056-1069
11. Chellan P., and Nagaraj R.H. Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes. Arch Biochem Biophys 368 (1999) 98-104
12. de Arriba S.G., Krugel U., Ralf R., Vissiennon Z., Verdanguer E., Lewerenz A., et al. Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity. Free Radical Biol Med 40 (2006) 779-790
13. de Arriba S.G., Stuchbury G., Yarin J., Burnell J., Loske C., and Munch G. Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells-protection by carbonyl scavengers. Neurobiol Aging 28 (2007) 1044-1050
14. Delaney C.L., Russell J.W., Cheng H.L., and Feldman E.L. Insulin like growth factor-I and over-expression of Bcl-xL prevent glucose-mediated apoptosis in Schwann cells. J Neuropathol Exp Neurol 60 (2001) 147-160
15. Di Loreto S., Zimmitti V., Sebastiani P., Cervelli C., Falone S., and Amicarelli F. Methylglyoxal causes strong weakening of detoxifying capacity and apoptotic cell death in rat hippocampal neurons. Int J Biochem Cell Biol 40 (2008) 245-257
16. Du J., Suzuki H., Nagase F.A., Akhand A., Yokoyama T., Miyata T., et al. Methylglyoxal induces apoptosis in Jurkat Leukemia cells by activating c-Jun N-terminal kinase. Cell Biochem 77 (2000) 333-344
17. Eichberg J. Protein kinase C changes in diabetes: is the concept relevant to neuropathy. Int Rev Neurobiol 50 (2002) 61-82
18. Fukunaga M., Miyata S., Higo S., Hamada Y., Ueyama S., and Kasuga M. Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells. Ann NY Acad Sci 1043 (2005) 151-157
19. Fukunaga M., Miyata S., Liu B.F., Miyazaki H., Hirota Y., Higo S., et al. Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells. Biochem Biophys Res Commun 320 (2004) 689-695
20. Hail G.M., Lo T.W., and Thornalley P.J. Methylglyoxal concentration and glyoxalase activities in the human lens. Exp Eye Res 59 (1994) 497-500
21. Huang SM, Chuang HC, Wu CH, Yen GC. Cytoprotective effects of phenolic acids on methylglyoxal-induced apoptosis in Neuro-2A cells. Mol Nutr Food Res; 2008, in press.
22. Huang S.M., Wu C.H., and Yen G.C. Effects of flavonoids on the expression of the pro-inflammatory response in human monocytes induced by ligation of the receptor for AGEs. Mol Nutr Food Res 50 (2006) 1129-1139
23. Kang Y., Edwards L.G., and Thornalley P.J. Effect of methylglyoxal on human leukaemia 60 cell growth: modification of DNA G1 growth arrest and induction of apoptosis. Leuk Res 20 (1996) 397-405
24. Lacerda L., Smith R.M., Opie L., and Lecour S. TNFα-induced cytoprotection requires the production of free radicals within mitochondria in C2C12 myotubes. Life Sci 79 (2006) 2194-2201
25. Lelkes E., Unsworth B.R., and Lelkes P.I. Reactive oxygen species, apoptosis and altered NGF-induced signaling in PC12 pheochromocytoma cells cultured in elevated glucose: an in vitro cellular model for diabetic neuropathy. Neurotox Res 3 (2001) 189-203
26. Monnier V.M. Nonenzymatic glycosylation, the Maillard reaction and the aging process. J Gerontol 45 (1990) 105-111
27. Nardini M., Pisu P., Gentili V., Natella F., Di F.M., Piccolell E., et al. Effect of caffeic acid on tert-butyl hydroperocide-induced oxidative stress in U937. Free Radical Biol Med 25 (1998) 1098-1105
28. Ota K., Nakamura J., Li W., Kozakae M., Watarai A., Nakamura N., et al. Metformin prevents methylglyoxal-induced apoptosis of mouse Scheann cells. Biochem Biophys Res Commun 25 (2007) 270-275
29. Picklo Sr. M.J., Montine T.J., Amarnath V., and Neely M.D. Carbonyl toxicology and Alzheimer's disease. Toxicol Appl Pharmacol 184 (2002) 187-197
30. Price S.A., Agthong S., Middlemas A.B., and Tomlinson D.R. Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase. Diabetes 53 (2004) 1851-1856
31. Schmeichel A.M., Schmelzer J.D., and Low P.A. Oxidative injury and apoptosis of dorsal root ganglion neurons in chronic experimental diabetic neuropathy. Diabetes 52 (2003) 165-171
32. Sharifi A.M., Mousavi S.H., Farhadi M., and Larijani B. Study of high glucose-induced apoptosis in PC12 cells: role of bax protein. J Pharmacol Sci 104 (2007) 258-262
33. Shyamala B.N., Madhava Naidu M., Sulochanamma G., and Srinivas P. Studies on the antioxidant activities of natural vanilla extract and its constituent compounds through in vitro models. J Agric Food Chem 55 (2007) 7738-7743
34. Singh R., Barden A., Mori T., and Beilin L. Advanced glycation end-products: a review. Diabetologia 44 (2001) 129-146
35. Thornalley P.J. Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification-a role in pathogenesis and antiproliferative chemotherapy. Gen Pharmacol 27 (1996) 565-573
36. Tomlinson D.R. Mitogen-activated protein kinases as glucose transducers for diabetic complications. Dibetilogia 42 (1999) 1271-1281
37. Uchida K., Khor O.T., Oya T., Osawa T., Yasuda Y., and Miyata T. Protein modification by a Maillard reaction intermediate methylglyoxal. Immunochemical detection of fluorescent 5-methylimidazolone derivatives in vivo. FEBS Lett 410 (1997) 313-318
38. Vincent A.M., Russell J.W., Low P., and Feldman E.L. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr Rev 25 (2004) 612-628
39. Wang H., Meng Q.H., Gordon J.R., Khandwala H., and Wu L. Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin Biochem 40 (2007) 1232-1239
40. Wu C.H., and Yen G.C. Inhibitory effect of naturally occurring flavonoids on the formation of advanced glycation endproducts. J Agric Food Chem 20 (2005) 3167-3173
41. Xu W., Zha R.P., Wang W.Y., and Wang Y.P. Effects of scutellarin on PKCgamma in PC12 cell injury induced by oxygen and glucose deprivation. Acta Pharmacol Sin 28 (2007) 1573-1579
42. Yen G.C., Duh P.D., Huang D.W., Hsu C.L., and Fu T.Y.C. Protective effect of pine (Pinus morrisonicola Hay.) needle on LDL oxidation and its anti-inflammatory action by modulation of iNOS and COX-2 expression in LPS-stimulated RAW 264.7 macrophages. Food Chem Toxicol 46 (2008) 175-185