Role of glucoxidation and lipid oxidation in the development of atherosclerosis

Annals of the New York Academy of Sciences

Volumn 1043, Issue , 2005, Pages 343-354

  Schleicher, Erwin ^a   Weigert, Cora ^a   Rohrbach, Helmut ^b   Nerlich, Andreas ^b   Bachmeier, Beatrice ^c   Friess, Ulrich ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b KLINIKUM BOGENHAUSEN   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Advanced glycation end products; Advanced lipid oxidation end products; Atherosclerosis; Carboxymethyllysine; Glucoxidation; Lipoxidation

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED LIPID OXIDATION END PRODUCT; ANGIOTENSIN; CARBOXYMETHYLLYSINE; CYTOCHROME P450; LYSINE; NITRIC OXIDE SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ACTIVATOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID; XANTHINE OXIDASE;

ATHEROMA; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CONFERENCE PAPER; GLUCOSE METABOLISM; GLYCOLYSIS; HUMAN; HUMAN CELL; LIPID OXIDATION; MONOCYTE; OXIDATIVE STRESS; PROTEIN LIPID INTERACTION; PROTEIN MODIFICATION; TISSUE REACTION; WOUND HEALING;

EID: 23744441018     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1333.041     Document Type: Conference Paper

References (23)

1. JESSUP, W., L. KRITHARIDES & R. STOCKER. 2004. Lipid oxidation in atherogenesis: an overview. Biochem. Soc. Trans. 32: 134-138.
2. NAKA, Y., L.G. BUCCIARELLI, T. WENDT, et al. 2004. RAGE axis: Animal models and novel insights into the vascular complications of diabetes. Arterioscler. Thromb. Vasc. Biol. 24: 1342-1349.
3. FU, M.X., J.R. REQUENA, A.J. JENKINS, et al. 1996. The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions. J. Biol. Chem. 271: 9982-9986.
4. JANUSZEWSKI, A.S., N.L. ALDERSON, T.O. METZ, et al. 2003. Role of lipids in chemical modification of proteins and development of complications in diabetes. Biochem. Soc. Trans. 31: 1413-1416.
5. THORNALLEY, P.J., A. LANGBORG & H.S. MINHAS. 1999. Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose. Biochem. J. 344: 109-116.
6. SCHLEICHER, E.D., E. WAGNER & A.G. NERLICH. 1997. Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. J. Clin. Invest. 99: 457-468.
7. GORLACH, A., R.P. BRANDES, K. NGUYEN, et al. 2000. A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall. Circ. Res. 87: 26-32.
8. ZIEGLER-HEITBROCK, H.W., W. SCHRAUT, P. WENDELGASS, et al. 1994. Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6. J. Leukoc. Biol. 55: 73-80.
9. PERKINS, S.L., D.C. LINK, S. KLING, et al. 1991. 1,25-Dihydroxyvitamin D3 induces monocytic differentiation of the PLB-985 leukemic line and promotes c-fgr mRNA expression. J. Leukoc. Biol. 50: 427-433.
10. WEIGERT, C., K. BRODBECK, F.C. BROSIUS, III, et al. 2003. Evidence for a novel TGF-beta1-independent mechanism of fibronectin production in mesangial cells overexpressing glucose transporters. Diabetes 52: 527-535.
11. GRIENDLING, K.K., C.A. MINIERI, J.D. OLLERENSHAW & R.W. ALEXANDER. 1994. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 74: 1141-1148.
12. GEMPEL, K.E., E.M. WAGNER & E.D. SCHLEICHER. 1994. Production and characterization of antibodies against carboxymethyllysine-modified proteins. In Maillard Reactions in Chemistry, Food and Health. Proceedings of the Fifth International Symposium on the Maillard Reaction, Minneapolis, 1993. TP. Labuza, G.A. Reineccius, V. Monnier, J. Obrien & J. Baynes, Eds.: 392-396. The Royal Society of Chemistry. Cambridge.
13. ONORATO, J.M., A.J. JENKINS, S.R. THORPE & J.W. BAYNES. 2000. Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine. J. Biol. Chem. 275: 21177-21184.
14. NERLICH, A.G. & E.D. SCHLEICHER. 1999. N(epsilon)-(carboxymethyl) lysine in atherosclerotic vascular lesions as a marker for local oxidative stress. Atherosclerosis 144: 41-47.
15. LASSEGUE, B. & R.E. CLEMPUS. 2003. Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285: R277-R297.
16. YU, L., A.R. CROSS, L. ZHEN & M.C. DINAUER. 1999. Functional analysis of NADPH oxidase in granulocytic cells expressing a delta488-497 gp91(phox) deletion mutant. Blood 94: 2497-2504.
17. LI, Y. & M.A. TRUSH. 1998. Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production. Biochem. Biophys. Res. Commun. 253: 295-299.
18. SORESCU, D., D. WEISS, B. LASSEGUE, et al. 2002. Superoxide production and expression of nox family proteins in human atherosclerosis. Circulation 105: 1429-1435.
19. HORIUCHI, S., H. SANO, T. HIGASHI, et al. 1996. Extra- and intracellular localization of advanced glycation end-products in human atherosclerotic lesions Nephrol. Dial. Transplant. 11(Suppl 5): 81-86.
20. SAKATA, N., Y. IMANAGA, J. MENG, et al. 1999. Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease. Atherosclerosis 142: 67-77.
21. ANDERSON, M.M. & J.W. HEINECKE. 2003. Production of N(epsilon)-(carboxymethyl)lysine is impaired in mice deficient in NADPH oxidase: a role for phagocyte-derived oxidants in the formation of advanced glycation end products during inflammation. Diabetes 52: 2137-2143.
22. ALDERSON, N.L., M.E. CHACHICH, N.N. YOUSSEF, et al. 2003. The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats. Kidney Int. 63: 2123-2133.
23. METZ, TO., N.L. ALDERSON, S.R. THORPE & J.W. BAYNES. 2003. Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications. Arch. Biochem. Biophys. 419: 41-49.