Ionizing radiation up-regulates telomerase activity in cancer cell lines by post-translational mechanism via ras/phosphatidylinositol 3-kinase/Akt pathway

Clinical Cancer Research

Volumn 15, Issue 3, 2009, Pages 914-923

  Ram, Ron ^a   Uziel, Orit ^a   Eldan, Orit ^a   Fenig, Eyal ^a   Beery, Einat ^a   Lichtenberg, Shelly ^a   Nordenberg, Yardena ^a   Lahav, Meir ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CALCIUM ION; EPIDERMAL GROWTH FACTOR RECEPTOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FARNESYLTHIOSALICYLIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; RAS PROTEIN; SOMATOMEDIN C RECEPTOR; SOMATOMEDIN RECEPTOR; TELOMERASE; WORTMANNIN;

ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IONIZING RADIATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROCESSING; RADIATION DOSE; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL COMPARTMENTATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; K562 CELLS; KINETICS; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RAS PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; SIGNAL TRANSDUCTION; TELOMERASE; UP-REGULATION;

EID: 61349145737     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-08-0792     Document Type: Article

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