T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Ramgolam, Vinod S ^a   DeGregorio, Scott D ^a   Rao, Gautham K ^a   Collinge, Mark ^a   Subaran, Sharmila S ^a   Markovic Plese, Silva ^b   Pardi, Ruggero ^c   Bender, Jeffrey R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HUR PROTEIN; INTEGRIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RAC1 PROTEIN; RAC2 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VAV 1 PROTEIN; CYTOKINE; ELAV-LIKE PROTEIN 1; GUANOSINE TRIPHOSPHATASE; MAP2K3 PROTEIN, HUMAN; MAP2K3 PROTEIN, MOUSE; MEMBRANE ANTIGEN; NEUROPEPTIDE; RAC PROTEIN; RAC1 PROTEIN, HUMAN; RAC1 PROTEIN, MOUSE; RNA BINDING PROTEIN; VAV PROTEIN; VAV1 PROTEIN, HUMAN; VAV1 PROTEIN, MOUSE;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PROTEIN PHOSPHORYLATION; RNA STABILITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; METABOLISM; MOUSE;

MUS;

ANIMALS; ANTIGENS, SURFACE; CYTOKINES; GTP PHOSPHOHYDROLASES; HUMANS; INTEGRINS; INTERFERON-GAMMA; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MAP KINASE KINASE 3; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-VAV; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78650816300     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014450     Document Type: Article

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