RGS/Gi2α interactions modulate platelet accumulation and thrombus formation at sites of vascular injury

Blood

Volumn 116, Issue 26, 2010, Pages 6092-6100

  Signarvic, Rachel S ^a   Cierniewska, Aleksandra ^a   Stalker, Timothy J ^a   Fong, Karen P ^a   Chatterjee, Manash S ^b   Hess, Paul R ^a   Ma, Peisong ^a   Diamond, Scott L ^b   Neubig, Richard R ^c   Brass, Lawrence F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC AMP; GLYCINE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN 2ALPHA; PROSTACYCLIN; PROTEIN KINASE B; RAP1 PROTEIN; RGS PROTEIN; SERINE; UNCLASSIFIED DRUG; CALCIUM;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL INJURY; CONTROLLED STUDY; ENZYME ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; THROMBOGENESIS; THROMBOSIS; ANIMAL; C57BL MOUSE; FEMALE; GENETICS; IMMUNOBLOTTING; MALE; METABOLISM; MUTATION; PATHOLOGY; PHOSPHORYLATION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT;

ANIMALS; BLOOD PLATELETS; CALCIUM; CYCLIC AMP; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; IMMUNOBLOTTING; MALE; MICE; MICE, INBRED C57BL; MUTATION; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET COUNT; PROTO-ONCOGENE PROTEINS C-AKT; RGS PROTEINS; SIGNAL TRANSDUCTION; THROMBOSIS; VASCULAR SYSTEM INJURIES;

EID: 78650662798     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-05-283846     Document Type: Article

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