Microfluidic focal thrombosis model for measuring murine platelet deposition and stability: PAR4 signaling enhances shear-resistance of platelet aggregates

Journal of Thrombosis and Haemostasis

Volumn 6, Issue 12, 2008, Pages 2193-2201

  Neeves, K B ^a,b   Maloney, S F ^a,b   Fong, K P ^b   Schmaier, A A ^b   Kahn, M L ^b   Brass, L F ^b   Diamond, Scott L ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Flow assay; Microfuidics; Murine platelets; Thrombus stability

Indexed keywords

FIBRINOGEN RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 4; THROMBIN; VERY LATE ACTIVATION ANTIGEN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY WALL; ARTICLE; BLOOD FLOW; BLOOD VISCOSITY; C57BL 6 MOUSE; CONTROLLED STUDY; FIBRIN FORMATION; FLOW RATE; KNOCKOUT MOUSE; MICROFLUIDIC ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHEAR RATE; SHEAR STRESS; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOSIS; VEIN WALL;

ANIMALS; COLLAGEN; DISEASE MODELS, ANIMAL; INTEGRIN ALPHA2BETA1; MICE; MICROFLUIDICS; PLATELET ADHESIVENESS; PLATELET AGGREGATION; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; THROMBOSIS;

EID: 56749092145     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2008.03188.x     Document Type: Article

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