Following activation of the amyloid cascade, apolipoprotein e4 drives the in vivo oligomerization of amyloid-β resulting in neurodegeneration

Journal of Alzheimer's Disease

Volumn 22, Issue 3, 2010, Pages 959-970

  Belinson, Haim ^a   Kariv Inbal, Zehavit ^a   Kayed, Rakez ^b   Masliah, Eliezer ^c   Michaelson, Daniel M ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyloid ; apolipoprotein E4; CA1 neurons; lysosomes; mitochondria; neurodegeneration

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; MEMBRANE METALLOENDOPEPTIDASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ORGANELLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INHIBITION; GENETIC RISK; IN VIVO STUDY; LYSOSOME; MALE; MITOCHONDRION; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; SHAM PROCEDURE;

EID: 78650644864     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-101008     Document Type: Article

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