IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 45, 2010, Pages 19420-19425

  Rousseau, Francois ^a,d   Basset, Laetitia ^a   Froger, Josy ^a,b   Dinguirard, Nathalie ^a   Chevalier, Sylvie ^a,b,c   Gascan, Hugues ^a,c  

^a ANGERS UNIVERSITY HOSPITAL   (France)

^b Infrastructures Biologie Santé et Agronomie Biogenouest   (France)

^c UNIVERSITÉ D'ANGERS   (France)

^d NOVIMMUNE SA   (Switzerland)

Author keywords

Cytokine; EBI3; Receptor; Structure; Th1

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CONCANAVALIN A; CYTOKINE RECEPTOR ANTAGONIST; GLYCOPROTEIN GP 130; INTERLEUKIN 27; UNCLASSIFIED DRUG; W 195A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; BINDING SITE; CELL DIFFERENTIATION; CONFERENCE PAPER; CONTROLLED STUDY; HEPATITIS; HUMAN; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; TH1 CELL; TH17 CELL;

MURINAE;

EID: 78650602324     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1005793107     Document Type: Article

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