Characterization of a potent human interleukin-11 agonist

Biochemical Journal

Volumn 375, Issue 1, 2003, Pages 23-32

  Harmegnies, Dimitri ^a   Wang, Xiao Ming ^a   Vandenbussche, Paul ^a   Leon, Arnaud ^b   Vusio, Patricia ^b   Grötzinger, Joachim ^c   Jacques, Yannick ^b   Goormaghtigh, Erik ^d   Devreese, Bart ^e   Content, Jean ^a  

^a PASTEUR INSTITUTE OF BRUSSELS   (Belgium)

^b INSTITUT DE BIOLOGIE   (France)

^c UNIVERSITY OF KIEL   (Germany)

^d FREE UNIVERSITY OF BRUSSELS   (Belgium)

^e GHENT UNIVERSITY   (Belgium)

Author keywords

Cytokine; Interleukin 11 (IL 11); Interleukin 11 agonist; Ligand binding; Molecular modelling; Site directed mutagenesis

Indexed keywords

ELECTROPHORESIS; INFRARED SPECTROSCOPY; PROTEINS;

NEUROGENESIS;

BIOCHEMISTRY;

GLYCOPROTEIN GP 130; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; INTERLEUKIN 11; INTERLEUKIN 11 RECEPTOR; MUTANT PROTEIN; RECOMBINANT INTERLEUKIN 11; ASPARTIC ACID; HISTIDINE; IL11RA PROTEIN, HUMAN; IL11RA1 PROTEIN, MOUSE; IL11RA2 PROTEIN, MOUSE; INTERLEUKIN 11 RECEPTOR ALPHA; INTERLEUKIN RECEPTOR;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SPECIFICITY; DRUG STRUCTURE; ELECTROPHORESIS; GEL FILTRATION; HYBRIDOMA; HYBRIDOMA CELL CULTURE; HYDROPHOBICITY; INFRARED SPECTROMETRY; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; WILD TYPE; ANIMAL; CELL DIVISION; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG POTENTIATION; GENETICS; HUMAN; INFRARED SPECTROPHOTOMETRY; METABOLISM; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

ANIMALIA; MURINAE;

ANIMALS; ASPARTIC ACID; CELL DIVISION; CELL LINE; CIRCULAR DICHROISM; HISTIDINE; HUMANS; HYDROPHOBICITY; INTERLEUKIN-11; INTERLEUKIN-11 RECEPTOR ALPHA SUBUNIT; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-11; SPECTROPHOTOMETRY, INFRARED;

EID: 0141905910     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030459     Document Type: Article

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