Protection of the Cyp1a2(-/-) null mouse against uroporphyria and hepatic injury following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Toxicology and Applied Pharmacology

Volumn 173, Issue 2, 2001, Pages 89-98

  Smith, Andrew G ^a   Clothier, Bruce ^a   Carthew, Philip ^a   Childs, Nicole L ^b   Sinclair, Peter R ^c   Nebert, Daniel W ^b   Dalton, Timothy P ^b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^c VA MEDICAL CENTER   (United States)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; CYP1A2; Liver damage; Uroporphyria

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 1A2; PORPHYRIN; UROPORPHYRIN; UROPORPHYRINOGEN DECARBOXYLASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; ENZYME INHIBITION; GENOTYPE; IRON OVERLOAD; LIVER CELL DAMAGE; LIVER INJURY; LIVER LEVEL; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PORPHYRIA; PORPHYRIA CUTANEA TARDA;

EID: 0035370158     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2001.9167     Document Type: Article

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