Role of cytochrome P450 1A2 in bilirubin degradation studies in Cyp1a2 (-/-) mutant mice

Biochemical Pharmacology

Volumn 61, Issue 7, 2001, Pages 843-849

  Zaccaro, Cinzia ^a   Sweitzer, Sarah ^b,c   Pipino, Sandra ^a   Gorman, Nadia ^b,c   Sinclair, Peter R ^b,c   Sinclair, Jacqueline F ^b,c   Nebert, Daniel W ^d   De Matteis, Francesco ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b VA MEDICAL CENTER   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

3,4,3 ,4 tetrachlorobiphenyl; Bilirubin degradation; Bilirubin oxidation by CYP1A enzymes; Congenital jaundice; CYP1A2; Cyp1a2 knockout mice

Indexed keywords

3 METHYLCHOLANTHRENE; 3,3',4,4' TETRACHLOROBIPHENYL; BETA NAPHTHOFLAVONE; BILIRUBIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BILIRUBIN BLOOD LEVEL; CATALYSIS; CELL MUTANT; CONTROLLED STUDY; CRIGLER NAJJAR SYNDROME; DEGRADATION; DOSE TIME EFFECT RELATION; GENE DISRUPTION; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BILIRUBIN; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DISEASE MODELS, ANIMAL; IRON-DEXTRAN COMPLEX; JAUNDICE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSOMES, LIVER; POLYCHLORINATED BIPHENYLS; RATS; RATS, GUNN; RATS, WISTAR; TERATOGENS; TETRACHLORODIBENZODIOXIN;

EID: 0035313418     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00568-8     Document Type: Article

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