Probing the structural determinants for the function of intracellular loop 2 in structurally cognate G-protein-coupled receptors

Biochemistry

Volumn 49, Issue 50, 2010, Pages 10691-10701

  Shan, Jufang ^a   Weinstein, Harel ^a,b   Mehler, Ernest L ^a  

^a Cornell University ^*  (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AB INITIO METHOD; ADRENERGIC RECEPTORS; ARRESTINS; CONFORMATIONAL ENSEMBLE; EXPERIMENTAL DATA; G PROTEIN; G PROTEIN COUPLED RECEPTORS; INTRACELLULAR LOOP 2; L-SHAPED; MOLECULAR MODELS; MONTE CARLO; SECONDARY STRUCTURES; STRUCTURAL BASIS; STRUCTURAL DETERMINANTS;

ARGON; CONFORMATIONS; MONTE CARLO METHODS; PROTEINS;

CRYSTAL STRUCTURE;

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; G PROTEIN COUPLED RECEPTOR; HELIX LOOP HELIX PROTEIN; INTRACELLULAR LOOP 2; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; GENE SEQUENCE; INTERNALIZATION; MONTE CARLO METHOD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SIMULATION; VALIDATION PROCESS;

ALGORITHMS; ANIMALS; CATTLE; HUMANS; MODELS, MOLECULAR; MONTE CARLO METHOD; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED;

EID: 78650369170     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100580s     Document Type: Article

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