SCOPUS 정보 검색 플랫폼

International Journal of Quantum Chemistry

Volumn 88, Issue 1, 2002, Pages 65-75

Structural motifs as functional microdomains in G-protein-coupled receptors: Energetic considerations in the mechanism of activation of the serotonin 5-HT2A receptor by disruption of the ionic lock of the arginine cage

(6) Visiers, Irache a Ebersole, Barbara J a Dracheva, Stella a Ballesteros, Juan a,b Sealfon, Stuart C a Weinstein, Harel a

a MOUNT SINAI SCHOOL OF MEDICINE (United States)

b Novasite Pharmaceuticals Inc (United States)

Author keywords

Computational simulation; Constitutive activity; Molecular electrostatic potential; Mutagenesis; Receptor activation

Indexed keywords

CHEMICAL ACTIVATION; COMPUTATION THEORY; COMPUTER SIMULATION; CONFORMATIONS; CYTOLOGY; ELECTRIC POTENTIAL; ELECTROSTATICS; FUNCTIONAL POLYMERS; MOLECULAR DYNAMICS; MOLECULAR STRUCTURE; MUTAGENESIS;

FUNCTIONAL MICRODOMAINS; G-PROTEIN-COUPLED RECEPTORS (GPCR); MOLECULAR ELECTROSTATIC POTENTIALS; STRUCTURAL MOTIFS;

PROTEINS;

EID: 0037066181 PISSN: 00207608 EISSN: None Source Type: Journal
DOI: 10.1002/qua.10078 Document Type: Article

Times cited : (43)

References (55)

1
- 0028909714
- (1995) J Mol Med , vol.73 , pp. 51-63
- Gudermann, T.¹ Nurnberg, B.² Schultz, G.³

2
- 0033118334
- (1999) EMBO J , vol.18 , pp. 1723-1729
- Bockaert, J.¹ Pin, J.P.²

3
- 0034604451
- (2000) Science , vol.289 , pp. 739-745
- Palczewski, K.¹ Kumasaka, T.² Hori, T.³ Behnke, C.A.⁴ Motoshima, H.⁵ Fox, B.A.⁶ Letrong, I.⁷ Teller, D.C.⁸ Okada, T.⁹ Stenkamp, R.E.¹⁰ Yamamoto, M.¹¹ Miyano, M.¹²

4
- 77957055780
- (1995) Methods Neurosci , vol.25 , pp. 366-428
- Ballesteros, J.A.¹ Weinstein, H.²

5
- 0034787251
- (2002) Methods Enzymol , vol.343 , pp. 329-371
- Visiers, I.¹ Ballesteros, J.A.² Weinstein, H.³

6
- 0004055467
- Structure-function analysis of G proteincoupled receptors
- Wiley-Liss: New York
- (1999) Receptor Biochemistry and Methodology
- Wess, J.¹

7
- 0035061847
- (2001) J Comput Aided Mol Design , vol.15 , pp. 297-307
- Filizola, M.¹ Villar, H.O.² Loew, G.H.³

8
- 0035185186
- (2001) Bioorg Med Chem , vol.9 , pp. 69-76
- Filizola, M.¹ Villar, H.O.² Loew, G.H.³

9
- 0033802976
- (2000) Bioorg Med Chem , vol.8 , pp. 2527-2538
- Harris, D.L.¹ Loew, G.²

10
- 0033935070
- (2000) Bioorg Med Chem , vol.8 , pp. 1799-1807
- Filizola, M.¹ Harris, D.L.² Loew, G.H.³

11
- 0034646311
- (2000) Biochemistry , vol.39 , pp. 2484-2498
- Chang, Y.T.¹ Loew, G.²

12
- 0032709594
- (1999) Protein Eng , vol.12 , pp. 927-942
- Filizola, M.¹ Laakkonen, L.² Loew, G.H.³

13
- 0031049537
- (1997) Protein Eng , vol.10 , pp. 119-129
- Chang, Y.T.¹ Stiffelman, O.B.² Vakser, I.A.³ Loew, G.H.⁴ Bridges, A.⁵ Waskell, L.⁶

14
- 0030607724
- (1996) Eur J Pharmacol , vol.318 , pp. 505-509
- Maguire, P.A.¹ Loew, G.H.²

15
- 0029906497
- (1996) Proteins , vol.26 , pp. 204-216
- Zhao, D.¹ Gilfoyle, D.J.² Smith, A.T.³ Loew, G.H.⁴

16
- 0030603161
- (1996) Eur J Pharmacol , vol.312 , pp. 241-244
- Chen, S.W.¹ Maguire, P.A.² Davies, M.F.³ Beatty, M.F.⁴ Loew, G.H.⁵

17
- 0029816447
- (1996) Protein Eng , vol.9 , pp. 755-766
- Chang, Y.T.¹ Loew, G.H.²

18
- 0029947902
- (1996) Protein Eng , vol.9 , pp. 573-583
- Alkorta, I.¹ Loew, G.H.²

19
- 0030443993
- (1996) Biochimie , vol.78 , pp. 771-779
- Chang, Y.T.¹ Stiffelnan, O.B.² Loew, G.H.³

20
- 0029907599
- (1996) Science , vol.274 , pp. 768-770
- Fattens, D.L.¹ Altenbach, C.² Yang, K.³ Hubbell, W.L.⁴ Khorana, H.G.⁵

21
- 0029778268
- (1996) Nature , vol.383 , pp. 347-350
- Sheikh, S.P.¹ Zvyaga, T.A.² Lichtarge, O.³ Sakmar, T.P.⁴ Bourne, H.R.⁵

22
- 0030611331
- (1997) J Biol Chem , vol.272 , pp. 18546-18549
- Javitch, J.A.¹ Fu, D.² Liapakis, G.³ Chen, J.⁴

23
- 0030859541
- (1997) Embo J , vol.16 , pp. 6737-6747
- Gether, U.¹ Lin, S.² Ghanouni, P.³ Ballesteros, J.A.⁴ Weinstein, H.⁵ Kobilka, B.K.⁶

24
- 0035937786
- (2001) J Biol Chem , vol.276 , pp. 9279-9290
- Jensen, A.D.¹ Guarnieri, F.² Rasmussen, S.G.³ Asmar, F.⁴ Ballesteros, J.A.⁵ Gether, U.⁶

25
- 0033061256
- (1999) Mol Pharmacol , vol.56 , pp. 175-184
- Rasmussen, S.G.¹ Jensen, A.D.² Liapakis, G.³ Ghanouni, P.⁴ Javitch, J.A.⁵ Gether, U.⁶

26
- 0028600609
- (1994) Protein Eng , vol.7 , pp. 1441-1448
- Luo, X.¹ Zhang, D.² Weinstein, H.³

27
- 0034327611
- (2000) Trends Pharmacol Sci , vol.21 , pp. 445-451
- Sansom, M.S.¹ Weinstein, H.²

28
- 0034603147
- (2000) J Biol Chem , vol.275 , pp. 3121-3127
- Ghanouni, P.¹ Schambye, H.² Seifert, R.³ Lee, T.W.⁴ Rasmussen, S.G.⁵ Gether, U.⁶ Kobilka, B.K.⁷

29
- 0027317273
- (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7849-7853
- Arnis, S.¹ Hofmarm, K.P.²

30
- 0028061193
- (1994) J Biol Chem , vol.269 , pp. 23879-23881
- Arnis, S.¹ Fahmy, K.² Hofmann, K.P.³ Sakmar, T.P.⁴

31
- 0029897495
- (1996) EMBO J , vol.15 , pp. 3566-3578
- Scheer, A.¹ Fanelli, F.² Costa, T.³ De Benedetti, P.G.⁴ Cotecchia, S.⁵

32
- 0027298812
- (1993) Biochemistry , vol.32 , pp. 6111-6115
- Cohen, G.B.¹ Yang, T.² Robinson, P.R.³ Oprian, D.D.⁴

33
- 0034112037
- (2000) Mol Pharmacol , vol.57 , pp. 890-898
- Alewijnse, A.E.¹ Timmerman, H.² Jacobs, E.H.³ Smit, M.J.⁴ Roovers, E.⁵ Cotecchia, S.⁶ Leurs, R.⁷

34
- 0035856560
- (2001) Biochemistry , vol.40 , pp. 13501-13509
- Huang, P.¹ Li, J.² Chen, C.³ Visiers, I.⁴ Weinstein, H.⁵ Liuchen, L.⁶

35
- 0027374544
- (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10206-10210
- Fahmy, K.¹ Jager, F.² Beck, M.³ Zvyaga, T.A.⁴ Sakmar, T.P.⁵ Siebert, F.⁶

36
- 0035800850
- (2001) J Biol Chem , vol.276 , pp. 29171-29177
- Ballesteros, J.A.¹ Jensen, A.D.² Liapakis, G.³ Rasmussen, S.G.⁴ Shi, L.⁵ Gether, U.⁶ Javitch, J.A.⁷

37
- 0032562699
- (1998) J Biol Chem , vol.273 , pp. 10445-10453
- Ballesteros, J.¹ Kitanovic, S.² Guamieri, F.³ Davies, P.⁴ Fromme, B.J.⁵ Konvicka, K.⁶ Chi, L.⁷ Millar, R.P.⁸ Davidson, J.S.⁹ Weinstein, H.¹⁰ Sealfon, S.C.¹¹

38
- 0027369421
- (1993) Nature , vol.365 , pp. 649-651
- Parma, J.¹ Duprez, L.² Van Sande, J.³ Cochaux, P.⁴ Gervy, C.⁵ Mockel, J.⁶ Dumont, J.⁷ Vassart, G.⁸

39
- 0028944574
- (1995) J Biol Chem , vol.270 , pp. 7405-7410
- Hogger, P.¹ Shockley, M.S.² Lameh, J.³ Sadee, W.⁴

40
- 0028944310
- (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1906-1910
- Laue, L.¹ Chan, W.Y.² Hsueh, A.J.³ Kudo, M.⁴ Hsu, S.Y.⁵ Wu, S.M.⁶ Blomberg, L.⁷ Cutler G.B., Jr.⁸

41
- 0027238736
- (1993) Mol Pharmacol , vol.43 , pp. 755-761
- Choudhary, M.S.¹ Craigo, S.² Roth, B.L.³

42
- 0028906185
- (1995) Mol Pharmacol , vol.47 , pp. 450-457
- Choudhary, M.S.¹ Sachs, N.² Uluer, A.³ Glennon, R.A.⁴ West-Kaemper, R.B.⁵ Roth, B.L.⁶

43
- 0033768889
- (2000) Protein Eng , vol.13 , pp. 603-606
- Visiers, I.¹ Braunheim, B.² Weinstein, H.³

44
- 84986486656
- (1991) J Comput Chem , vol.12 , pp. 435-445
- Nicholls, A.¹ Honig, B.²

45
- 0026345868
- (1991) Biochem Biophys Res Commun , vol.181 , pp. 1469-1478
- Saltzman, A.G.¹ Morse, B.² Whitman, M.M.³ Ivanshchenko, Y.⁴ Jaye, M.⁵ Felder, S.⁶

46
- 19744378683
- Receptor molecular biology
- Corm, P. M., Ed.; Academic: New York
- Methods in Neurosciences , vol.25
- Sealfon, S.C.¹

47
- 71849104860
- (1951) J Biol Chem , vol.193 , pp. 265-275
- Lowry, O.H.¹ Rosebrough, N.J.² Farr, A.L.³ Randall, R.J.⁴

48
- 0031033944
- (1997) Biochemistry , vol.36 , pp. 633-639
- Hwa, J.¹ Galvin, R.² Porter, J.E.³ Perez, D.M.⁴

49
- 0031029841
- (1997) J Recept Signal Transduct Res , vol.17 , pp. 57-73
- Scheer, A.¹ Cotecchia, S.²

50
- 0028061193
- (1994) J Biol Chem , vol.269 , pp. 23879-23881
- Arnis, S.¹ Fahmy, K.² Hofmann, K.P.³ Sakmar, T.P.⁴

51
- 0027298812
- (1993) Biochemistry , vol.32 , pp. 6111-6115
- Cohen, G.B.¹ Yang, T.² Robinson, P.R.³ Oprian, D.D.⁴

52
- 0030614337
- (1997) Proc Natl Acad Sci USA , vol.94 , pp. 808
- Scheer, A.¹ Fanelli, F.² Costa, T.³ De Benedetti, P.G.⁴ Cotecchia, S.⁵

53
- 0031780235
- (1998) Mol Pharmacol , vol.53 , pp. 894-901
- Kosugi, S.¹ Mori, T.² Shenker, A.³

54
- 0029898348
- (1996) Trends Pharmacol Sci , vol.17 , pp. 213-216
- Schwartz, T.W.¹ Rosenkilde, M.M.²

55
- 0028276459
- (1994) TIPS , vol.15 , pp. 170-172
- Oliveira, L.¹ Paiva, A.C.M.² Sander, C.³ Vriend, G.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.