The role of hydrophobic microenvironments in modulating pKa shifts in proteins

Proteins: Structure, Function and Genetics

Volumn 48, Issue 2, 2002, Pages 283-292

  Mehler, E L ^a   Fuxreiter, M ^b   Simon, I ^b   Garcia Moreno E, B ^c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF ENZYMOLOGY   (Hungary)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hydrophobicity of microenvironments; PKa and hydrophobicity; PKa in proteins; Protein electrostatics; Solvation

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); LYSOZYME; NUCLEASE; PROTEIN;

ALGORITHM; ARTICLE; CALCULATION; CALIBRATION; CATALYSIS; ELECTRON TRANSPORT; HYDROPHOBICITY; IONIZATION; PKA; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON TRANSPORT; STAPHYLOCOCCUS;

ALGORITHMS; AMINE OXIDASE (COPPER-CONTAINING); AMINO ACIDS; ASPARTIC ACID; BINDING SITES; ELECTROSTATICS; HISTIDINE; HYDROPHOBICITY; MICROCOCCAL NUCLEASE; MODELS, CHEMICAL; MODELS, THEORETICAL; MURAMIDASE; PROTEINS; SOLVENTS; TITRIMETRY;

EID: 0036681396     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10153     Document Type: Article

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