RNA-editing of the 5-HT2C receptor alters agonist-receptor-effector coupling specificity

British Journal of Pharmacology

Volumn 134, Issue 2, 2001, Pages 386-392

  Berg, Kelly A ^a   Cropper, Jodie D ^a   Niswender, Colleen M ^b   Sanders Bush, Elaine ^b   Emeson, Ronald B ^b   Clarke, William P ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

Agonist trafficking; Eceptor effector coupling; Efficacy; G protein coupled receptors; RNA editing; Serotonin receptors; Signal transduction

Indexed keywords

1 (3 TRIFLUOROMETHYLPHENYL)PIPERAZINE; ARACHIDONIC ACID; BUFOTENINE; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; RECEPTOR SUBUNIT; RNA; SEROTONIN 2C AGONIST; SEROTONIN 2C RECEPTOR; SEROTONIN 2C RECEPTOR VGV; SEROTONIN 2C RECEPTOR VSV; SEROTONIN AGONIST; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; EFFECTOR CELL; INTRACELLULAR TRANSPORT; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; RECEPTOR AFFINITY; RNA EDITING; SEROTONIN RELEASE; SIGNAL TRANSDUCTION;

EID: 0034781254     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704255     Document Type: Article

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