Astaxanthin protects against MPTP/MPP+-induced mitochondrial dysfunction and ROS production in vivo and in vitro

Food and Chemical Toxicology

Volumn 49, Issue 1, 2011, Pages 271-280

  Lee, Dae Hee ^a   Kim, Cuk Seong ^a   Lee, Yong J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Astaxanthin; MPTP; Parkinson's disease; Substantia nigra neuron

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA SYNUCLEIN; ANTIOXIDANT; ASTAXANTHIN; CASPASE 3; CATALASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL DAMAGE; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; DOWN REGULATION; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; MOUSE; NEUROBLASTOMA CELL; NEUROPROTECTION; NONHUMAN; OXIDATION; PARKINSON DISEASE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SUBSTANTIA NIGRA; UPREGULATION;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; ANTIOXIDANTS; CASPASE 3; CATALASE; CELL LINE, TUMOR; CYTOCHROMES; ENZYME ACTIVATION; ENZYME INDUCTION; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MICE; MICE, INBRED BALB C; MITOCHONDRIA; MPTP POISONING; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; XANTHOPHYLLS;

EID: 78650257134     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.10.029     Document Type: Article

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