메뉴 건너뛰기




Volumn 4, Issue 1 A, 2008, Pages 11-20

Rasagiline in treatment of Parkinson's disease

Author keywords

Monoamine oxidase inhibitor; Parkinson's disease; Propargylamine; Rasagiline

Indexed keywords

ENTACAPONE; LEVODOPA; PLACEBO; RASAGILINE; SELEGILINE; TEVA; TEVA EISAI; UNCLASSIFIED DRUG;

EID: 41549092261     PISSN: 11766328     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (27)

References (64)
  • 1
    • 0037189081 scopus 로고    scopus 로고
    • An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells
    • Akao Y, Maruyama W, Yi H, et al 2002. An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells. Neurosci Lett, 326:105-8.
    • (2002) Neurosci Lett , vol.326 , pp. 105-108
    • Akao, Y.1    Maruyama, W.2    Yi, H.3
  • 2
    • 34147164484 scopus 로고    scopus 로고
    • Neuroprotection in Parkinson's disease:an elusive goal
    • Biglan KM, Ravina B. 2007. Neuroprotection in Parkinson's disease:an elusive goal. Semin Neurol, 27:106-12.
    • (2007) Semin Neurol , vol.27 , pp. 106-112
    • Biglan, K.M.1    Ravina, B.2
  • 3
    • 0026099424 scopus 로고
    • Monoamine oxidase inhibitor interactions with other drugs
    • Blackwell B. 1991. Monoamine oxidase inhibitor interactions with other drugs. J Clin Psychopharmacol, 11:55-9.
    • (1991) J Clin Psychopharmacol , vol.11 , pp. 55-59
    • Blackwell, B.1
  • 4
    • 2342547676 scopus 로고    scopus 로고
    • Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease
    • Blandini F, Armentero MT, Fancellu R, et al 2004. Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease. Exp Neurol, 187:455-9.
    • (2004) Exp Neurol , vol.187 , pp. 455-459
    • Blandini, F.1    Armentero, M.T.2    Fancellu, R.3
  • 5
    • 0037333666 scopus 로고    scopus 로고
    • Staging of brain pathology related to sporadic Parkinson's disease
    • Braak H, Del Tredici K, Rub U, et al. 2003. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging, 24:197-211.
    • (2003) Neurobiol Aging , vol.24 , pp. 197-211
    • Braak, H.1    Del Tredici, K.2    Rub, U.3
  • 6
    • 23044514579 scopus 로고    scopus 로고
    • Clinical pharmacology of rasagiline:a novel, second-generation propargylamine for the treatment of Parkinson disease
    • Chen JJ, Swope DM. 2005. Clinical pharmacology of rasagiline:a novel, second-generation propargylamine for the treatment of Parkinson disease. J Clin Pharmacol, 45:878-94.
    • (2005) J Clin Pharmacol , vol.45 , pp. 878-894
    • Chen, J.J.1    Swope, D.M.2
  • 7
    • 0014965307 scopus 로고
    • Multiple forms of human brain mitochondrial monoamine oxidase
    • Collins GG, Sandler M, Williams ED, et al. 1970. Multiple forms of human brain mitochondrial monoamine oxidase. Nature, 225:817-20.
    • (1970) Nature , vol.225 , pp. 817-820
    • Collins, G.G.1    Sandler, M.2    Williams, E.D.3
  • 8
    • 33750296512 scopus 로고    scopus 로고
    • Effects of tyramine administration in Parkinson's disease patients treated with selective MAO-B inhibitor rasagiline
    • Demarcaida JA, Schwid SR, White WB, et al. 2006. Effects of tyramine administration in Parkinson's disease patients treated with selective MAO-B inhibitor rasagiline. Mov Disord, 21:1716-21.
    • (2006) Mov Disord , vol.21 , pp. 1716-1721
    • Demarcaida, J.A.1    Schwid, S.R.2    White, W.B.3
  • 9
    • 33750480538 scopus 로고    scopus 로고
    • Rasagiline-associated motor improvement in PD occurs without worsening of cognitive and behavioral symptoms
    • Elmer L, Schwid S, Eberly S, et al. 2006. Rasagiline-associated motor improvement in PD occurs without worsening of cognitive and behavioral symptoms. J Neurol Sci, 248:78-83.
    • (2006) J Neurol Sci , vol.248 , pp. 78-83
    • Elmer, L.1    Schwid, S.2    Eberly, S.3
  • 10
    • 0038727936 scopus 로고    scopus 로고
    • Description of Parkinson's disease as a clinical syndrome
    • Falm S. 2003. Description of Parkinson's disease as a clinical syndrome. Ann N Y Acad Sci, 991:1-14.
    • (2003) Ann N Y Acad Sci , vol.991 , pp. 1-14
    • Falm, S.1
  • 11
    • 0038015683 scopus 로고    scopus 로고
    • Malignant melanoma and levodopa in Parkinson's disease:causality or coincidence?
    • Fiala K-H, Whetteckey J, Manyam BV. 2003. Malignant melanoma and levodopa in Parkinson's disease:causality or coincidence? Parkinsonism Relat Disord, 9:321-7.
    • (2003) Parkinsonism Relat Disord , vol.9 , pp. 321-327
    • Fiala, K.-H.1    Whetteckey, J.2    Manyam, B.V.3
  • 13
    • 0032498811 scopus 로고    scopus 로고
    • Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor
    • Finberg JP, Takeshima T, Johnston JM, et al. 1998. Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor. Neuroreport, 9:703-7.
    • (1998) Neuroreport , vol.9 , pp. 703-707
    • Finberg, J.P.1    Takeshima, T.2    Johnston, J.M.3
  • 14
    • 0031596702 scopus 로고    scopus 로고
    • Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey
    • Finberg JP, Wang J, Bankiewicz K, et al. 1998. Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey. J Neural Transm Suppl, 52:279-85.
    • (1998) J Neural Transm Suppl , vol.52 , pp. 279-285
    • Finberg, J.P.1    Wang, J.2    Bankiewicz, K.3
  • 15
    • 0027981209 scopus 로고
    • Slow recovery of human brain MAO B after L-deprenyl (Selegeline) withdrawal
    • Fowler JS, Volkow ND, Logan J, et al. 1994. Slow recovery of human brain MAO B after L-deprenyl (Selegeline) withdrawal. Synapse, 18:86-93.
    • (1994) Synapse , vol.18 , pp. 86-93
    • Fowler, J.S.1    Volkow, N.D.2    Logan, J.3
  • 16
    • 27944481562 scopus 로고    scopus 로고
    • In vivo measurement of brain monoamine oxidase B (MAO-B activity after rasagiline treatment, using L-[11C]Deprenyl and positron emission tomography (PET)
    • Freedman N, Mishani E, Krausz Y, et al. 2005. In vivo measurement of brain monoamine oxidase B (MAO-B activity after rasagiline treatment, using L-[11C]Deprenyl and positron emission tomography (PET). Movement Disorders, S89:P298.
    • (2005) Movement Disorders, S89
    • Freedman, N.1    Mishani, E.2    Krausz, Y.3
  • 17
    • 33646676086 scopus 로고    scopus 로고
    • Safety of rasagiline in elderly patients with Parkinson disease
    • Goetz CG, Schwid SR, Eberly SW, et al. 2006. Safety of rasagiline in elderly patients with Parkinson disease. Neuroloy, 66:1427-9.
    • (2006) Neuroloy , vol.66 , pp. 1427-1429
    • Goetz, C.G.1    Schwid, S.R.2    Eberly, S.W.3
  • 18
    • 0034526673 scopus 로고    scopus 로고
    • The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture
    • Goggi J, Theofilopoulos S, Riaz SS, et al. 2000. The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture. Neuroreport, 11:3937-41.
    • (2000) Neuroreport , vol.11 , pp. 3937-3941
    • Goggi, J.1    Theofilopoulos, S.2    Riaz, S.S.3
  • 19
    • 0017755902 scopus 로고
    • Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine
    • Green AR, Mitchell BD, Tordoff AF, et al. 1977. Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine. Br J Pharmacol, 60:343-9.
    • (1977) Br J Pharmacol , vol.60 , pp. 343-349
    • Green, A.R.1    Mitchell, B.D.2    Tordoff, A.F.3
  • 20
    • 0033407094 scopus 로고    scopus 로고
    • Dopaminergic neurons degenerate by apoptosis in Parkinson's disease
    • Hirsch EC, Hunot S, Faucheux B, et al. 1999. Dopaminergic neurons degenerate by apoptosis in Parkinson's disease. Mov Disord, 14:383-5.
    • (1999) Mov Disord , vol.14 , pp. 383-385
    • Hirsch, E.C.1    Hunot, S.2    Faucheux, B.3
  • 21
    • 34447301510 scopus 로고    scopus 로고
    • Clinical trials for neuroprotection in Parkinson's disease:overcoming angst and futility?
    • Hung AY, Schwarzschild MA. 2007. Clinical trials for neuroprotection in Parkinson's disease:overcoming angst and futility? Curr Opin Neurol, 20:477-83.
    • (2007) Curr Opin Neurol , vol.20 , pp. 477-483
    • Hung, A.Y.1    Schwarzschild, M.A.2
  • 22
    • 2042540046 scopus 로고    scopus 로고
    • Therapeutic factors causing hallucination in Parkinson's disease patients, especially those given selegiline
    • Kamakura K, Mochizuki H, Kaida Y, et al. 2004. Therapeutic factors causing hallucination in Parkinson's disease patients, especially those given selegiline. Parkinsonism Relat Disord, 10:235-42.
    • (2004) Parkinsonism Relat Disord , vol.10 , pp. 235-242
    • Kamakura, K.1    Mochizuki, H.2    Kaida, Y.3
  • 23
    • 34147181610 scopus 로고    scopus 로고
    • The progression of Parkinson disease:a hypothesis
    • Lang AE. 2007. The progression of Parkinson disease:a hypothesis. Neurology, 68:948-52.
    • (2007) Neurology , vol.68 , pp. 948-952
    • Lang, A.E.1
  • 24
    • 1942520420 scopus 로고    scopus 로고
    • Challenges in Parkinson's disease:restoration of the nigrostriatal dopamine system is not enough
    • Lang AE, Obeso JA. 2004. Challenges in Parkinson's disease:restoration of the nigrostriatal dopamine system is not enough. Lancet Neurol, 3:309-16.
    • (2004) Lancet Neurol , vol.3 , pp. 309-316
    • Lang, A.E.1    Obeso, J.A.2
  • 25
    • 8844287467 scopus 로고    scopus 로고
    • The neuropsychiatry of Parkinson's disease and related disorders
    • Lauterbach EC. 2004. The neuropsychiatry of Parkinson's disease and related disorders. Psychiatr Clin North Am, 27:801-25.
    • (2004) Psychiatr Clin North Am , vol.27 , pp. 801-825
    • Lauterbach, E.C.1
  • 26
    • 34248550990 scopus 로고    scopus 로고
    • Neuroprotection for Parkinson's disease
    • Lewitt PA. 2006. Neuroprotection for Parkinson's disease. J Neural Transm Suppl, 113-22.
    • (2006) J Neural Transm Suppl , pp. 113-122
    • Lewitt, P.A.1
  • 27
    • 17844406615 scopus 로고    scopus 로고
    • Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives
    • Mandel S, Weinreb O, Amit T, et al. 2005. Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives. Brain Res Brain Res Rev, 48:379-87.
    • (2005) Brain Res Brain Res Rev , vol.48 , pp. 379-387
    • Mandel, S.1    Weinreb, O.2    Amit, T.3
  • 28
    • 0036719861 scopus 로고    scopus 로고
    • Neuroprotection by propargylamines in Parkinson's disease:suppression of apoptosis and induction of prosurvival genes
    • Maruyama W, Akao Y, Carrillo MC, et al. 2002. Neuroprotection by propargylamines in Parkinson's disease:suppression of apoptosis and induction of prosurvival genes. Neurotoxicol Teratol, 24:675-82.
    • (2002) Neurotoxicol Teratol , vol.24 , pp. 675-682
    • Maruyama, W.1    Akao, Y.2    Carrillo, M.C.3
  • 29
    • 0034884148 scopus 로고    scopus 로고
    • Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol
    • Maruyama W, Akao Y, Youdim MB, et al. 2001. Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol. J Neurochem, 79:727-35.
    • (2001) J Neurochem , vol.79 , pp. 727-735
    • Maruyama, W.1    Akao, Y.2    Youdim, M.B.3
  • 30
    • 0346848857 scopus 로고    scopus 로고
    • N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor
    • Maruyama W, Nitta A, Shamoto-Nagai M, et al. 2004. N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappaB transcription factor. Neurochem Int, 44:393-400.
    • (2004) Neurochem Int , vol.44 , pp. 393-400
    • Maruyama, W.1    Nitta, A.2    Shamoto-Nagai, M.3
  • 31
    • 0034548019 scopus 로고    scopus 로고
    • Adverse drug reactions to selegiline:a review of the French pharmacovigilance database
    • Montastruc JL, Chaumerliac C, Desboeuf Y, et al. 2000. Adverse drug reactions to selegiline:a review of the French pharmacovigilance database. Clin Neuropharmacol, 23:271-5.
    • (2000) Clin Neuropharmacol , vol.23 , pp. 271-275
    • Montastruc, J.L.1    Chaumerliac, C.2    Desboeuf, Y.3
  • 32
    • 34248549035 scopus 로고    scopus 로고
    • Involvement of type A monoamine oxidase in neurodegeneration:regulation of mitochondrial signaling leading to cell death or neuroprotection
    • Naoi M, Maruyama W, Akao Y, et al. 2006. Involvement of type A monoamine oxidase in neurodegeneration:regulation of mitochondrial signaling leading to cell death or neuroprotection. J Neural Transm Suppl, 67-77.
    • (2006) J Neural Transm Suppl , pp. 67-77
    • Naoi, M.1    Maruyama, W.2    Akao, Y.3
  • 33
    • 0020662487 scopus 로고
    • The deamination of dopamine by human brain monoamine oxidase. Specificity for the two enzyme forms in seven brain regions
    • O'Carroll AM, Fowler CJ, Phillips JP, et al. 1993. The deamination of dopamine by human brain monoamine oxidase. Specificity for the two enzyme forms in seven brain regions. Naunyn Schmiedebergs Arch Pharmacol, 322:198-202.
    • (1993) Naunyn Schmiedebergs Arch Pharmacol , vol.322 , pp. 198-202
    • O'Carroll, A.M.1    Fowler, C.J.2    Phillips, J.P.3
  • 34
    • 33744980931 scopus 로고    scopus 로고
    • Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease
    • Olanow CW. 2006. Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease. Neurology, 66:S69-79.
    • (2006) Neurology , vol.66
    • Olanow, C.W.1
  • 35
    • 0024456653 scopus 로고
    • Effect of deprenyl on the progression of disability in early Parkinson's disease
    • Parkinson Study Group
    • Parkinson Study Group. 1989. Effect of deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med, 321:1364-71.
    • (1989) N Engl J Med , vol.321 , pp. 1364-1371
  • 36
    • 0027530638 scopus 로고
    • Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
    • Parkinson Study Group
    • Parkinson Study Group. 1993. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med, 328:176-83.
    • (1993) N Engl J Med , vol.328 , pp. 176-183
  • 37
    • 0036894795 scopus 로고    scopus 로고
    • A controlled trial of rasagiline in early Parkinson disease:the TEMPO Study
    • Parkinson Study Group
    • Parkinson Study Group 2002. A controlled trial of rasagiline in early Parkinson disease:the TEMPO Study. Arch Neurol, 59:1937-43.
    • (2002) Arch Neurol , vol.59 , pp. 1937-1943
  • 38
    • 2342655732 scopus 로고    scopus 로고
    • A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease
    • Parkinson Study Group
    • Parkinson Study Group. 2004. A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease. Arch Neurol, 61:561-6.
    • (2004) Arch Neurol , vol.61 , pp. 561-566
  • 39
    • 13444302612 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson disease and motor fluctuations:the PRESTO study
    • Parkinson Study Group
    • Parkinson Study Group. 2005. A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson disease and motor fluctuations:the PRESTO study. Arch Neurol, 62:241-8.
    • (2005) Arch Neurol , vol.62 , pp. 241-248
  • 40
    • 0034519674 scopus 로고    scopus 로고
    • Rasagiline mesylate, a new MAO-B inhibitor for the treatment of Parkinson's disease:a double-blind study as adjunctive therapy to levodopa
    • Rabey JM, Sagi I, Huberman M, et al. 2000. Rasagiline mesylate, a new MAO-B inhibitor for the treatment of Parkinson's disease:a double-blind study as adjunctive therapy to levodopa. Clin Neuropharmacol, 23:324-30.
    • (2000) Clin Neuropharmacol , vol.23 , pp. 324-330
    • Rabey, J.M.1    Sagi, I.2    Huberman, M.3
  • 41
    • 15844386001 scopus 로고    scopus 로고
    • Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): A randomised, double-blind, parallel-group trial
    • Rascol O, Brooks DJ, Melamed E, et al. 2005. Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial. Lancet, 365:947-54.
    • (2005) Lancet , vol.365 , pp. 947-954
    • Rascol, O.1    Brooks, D.J.2    Melamed, E.3
  • 42
    • 0030987172 scopus 로고    scopus 로고
    • Serotonin syndrome and the combined use of deprenyl and an antidepressant in Parkinson's disease. Parkinson Study Group
    • Richard IH, Kurlan R, Tanner C, et al, 1997. Serotonin syndrome and the combined use of deprenyl and an antidepressant in Parkinson's disease. Parkinson Study Group. Neurology, 48:1070-7.
    • (1997) Neurology , vol.48 , pp. 1070-1077
    • Richard, I.H.1    Kurlan, R.2    Tanner, C.3
  • 43
  • 44
    • 0022496317 scopus 로고
    • Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with 1-deprenyl
    • Riederer P, Youdim MB. 1986. Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with 1-deprenyl. J Neurochem, 46:1359-65.
    • (1986) J Neurochem , vol.46 , pp. 1359-1365
    • Riederer, P.1    Youdim, M.B.2
  • 45
    • 0030807313 scopus 로고    scopus 로고
    • Retrospective study of selegiline-antidepressant drug interactions and a review of the literature
    • Ritter JL, Alexander B. 1997. Retrospective study of selegiline-antidepressant drug interactions and a review of the literature. Ann Clin Psychiatry, 9:7-13.
    • (1997) Ann Clin Psychiatry , vol.9 , pp. 7-13
    • Ritter, J.L.1    Alexander, B.2
  • 46
    • 0346124141 scopus 로고    scopus 로고
    • Treatments of Parkinson disease: Circa 2003
    • Shults CW. 2003. Treatments of Parkinson disease: circa 2003. Arch Neurol, 60:1680-4.
    • (2003) Arch Neurol , vol.60 , pp. 1680-1684
    • Shults, C.W.1
  • 47
    • 0031596710 scopus 로고    scopus 로고
    • Effects of N-propargyl-1-(R)ammoindan (rasagiline) in models of motor and cognition disorders
    • Speiser Z, Levy R, Cohen S. 1998. Effects of N-propargyl-1-(R)ammoindan (rasagiline) in models of motor and cognition disorders. J Neural Transm Suppl, 52:287-300.
    • (1998) J Neural Transm Suppl , vol.52 , pp. 287-300
    • Speiser, Z.1    Levy, R.2    Cohen, S.3
  • 48
    • 0015272059 scopus 로고
    • Multiple forms of monoamine oxidase in intact mitochondria as characterized by selective inhibitors and thermal stability: A comparison of eight mammalian species
    • Squires RF. 1972. Multiple forms of monoamine oxidase in intact mitochondria as characterized by selective inhibitors and thermal stability: a comparison of eight mammalian species. Adv Biochem Psychopharmacol, 5:355-70.
    • (1972) Adv Biochem Psychopharmacol , vol.5 , pp. 355-370
    • Squires, R.F.1
  • 49
    • 4444338196 scopus 로고    scopus 로고
    • Double-blind, randomized, controlled trial of rasagiline as monotherapy in early Parkinson's disease patients
    • Stem MB, Marek KL, Friedman J, et al. 2004. Double-blind, randomized, controlled trial of rasagiline as monotherapy in early Parkinson's disease patients. Mov Disord, 19:916-23.
    • (2004) Mov Disord , vol.19 , pp. 916-923
    • Stem, M.B.1    Marek, K.L.2    Friedman, J.3
  • 50
    • 0025869797 scopus 로고
    • The serotonin syndrome
    • Sternbach H. 1991. The serotonin syndrome. Am J Psychiatry, 148:705-13.
    • (1991) Am J Psychiatry , vol.148 , pp. 705-713
    • Sternbach, H.1
  • 51
    • 0025195904 scopus 로고
    • Possible interactions between deprenyl and prozac
    • Suchowersky O, Devries J. 1990. Possible interactions between deprenyl and prozac. Can J Neurol Sci, 17:352-3.
    • (1990) Can J Neurol Sci , vol.17 , pp. 352-353
    • Suchowersky, O.1    Devries, J.2
  • 52
    • 0034684149 scopus 로고    scopus 로고
    • Dopamine agonists in early therapy for Parkinson disease: Promise and problems
    • Tanner CM. 2000. Dopamine agonists in early therapy for Parkinson disease: promise and problems. Jama, 284:1971-3.
    • (2000) Jama , vol.284 , pp. 1971-1973
    • Tanner, C.M.1
  • 53
    • 4644317791 scopus 로고    scopus 로고
    • Tolerability, safety, pharmacodynamics, and pharmacokinetics of rasagiline:a potent, selective, and irreversible monoamine oxidase type B inhibitor
    • Thebault JJ, Guillaume M, Levy R. 2004. Tolerability, safety, pharmacodynamics, and pharmacokinetics of rasagiline:a potent, selective, and irreversible monoamine oxidase type B inhibitor. Pharmacotherapy, 24:1295-305.
    • (2004) Pharmacotherapy , vol.24 , pp. 1295-1305
    • Thebault, J.J.1    Guillaume, M.2    Levy, R.3
  • 54
    • 0028215440 scopus 로고
    • Is it safe to combine a selective serotonin reuptake inhibitor with selegiline?
    • Toyama SC, Iacono RP. 1994. Is it safe to combine a selective serotonin reuptake inhibitor with selegiline? Ann Pharmacother, 28:405-6.
    • (1994) Ann Pharmacother , vol.28 , pp. 405-406
    • Toyama, S.C.1    Iacono, R.P.2
  • 55
    • 0027980832 scopus 로고
    • Fluoxetine and selegiline - lack of significant interaction
    • Waters CH. 1994. Fluoxetine and selegiline - lack of significant interaction. Can J Neurol Sci, 21:259-61.
    • (1994) Can J Neurol Sci , vol.21 , pp. 259-261
    • Waters, C.H.1
  • 56
    • 29744449650 scopus 로고    scopus 로고
    • Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: Interaction of Bcl-2 family members with PKC pathway
    • Weinreb O, Amit T, Bar-Am O, et al. 2005. Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway. Ann N Y Acad Sci, 1053:348-55.
    • (2005) Ann N Y Acad Sci , vol.1053 , pp. 348-355
    • Weinreb, O.1    Amit, T.2    Bar-Am, O.3
  • 57
    • 29244431681 scopus 로고    scopus 로고
    • N-Propargylamine protects SH-SY5Y cells from apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, through stabilization of mitochondrial membrane and induction of anti-apoptotic Bcl-2
    • Yi H, Maruyama W, Akao Y, et al. 2006. N-Propargylamine protects SH-SY5Y cells from apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, through stabilization of mitochondrial membrane and induction of anti-apoptotic Bcl-2. J Neural Transm, 113:21-32.
    • (2006) J Neural Transm , vol.113 , pp. 21-32
    • Yi, H.1    Maruyama, W.2    Akao, Y.3
  • 58
    • 84987398201 scopus 로고
    • The advent of selective monoamine oxidase A inhibitor antidepressants devoid of the cheese reaction
    • Youdim MB. 1995. The advent of selective monoamine oxidase A inhibitor antidepressants devoid of the cheese reaction. Acta Psychiatr Scand Suppl, 386:5-7.
    • (1995) Acta Psychiatr Scand Suppl , vol.386 , pp. 5-7
    • Youdim, M.B.1
  • 59
    • 12244296145 scopus 로고    scopus 로고
    • Rasagiline: Neurodegeneration, neuroprotection, and mitochondrial permeability transition
    • Youdim MB, Bar Am O, Yogev-Falach M, et al. 2005. Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition. J Neurosci Res, 79:172-9.
    • (2005) J Neurosci Res , vol.79 , pp. 172-179
    • Youdim, M.B.1    Bar, A.O.2    Yogev-Falach, M.3
  • 60
    • 0035130289 scopus 로고    scopus 로고
    • Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B
    • Youdim MB, Gross A, Finberg JP. 2001. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol, 132:500-6.
    • (2001) Br J Pharmacol , vol.132 , pp. 500-506
    • Youdim, M.B.1    Gross, A.2    Finberg, J.P.3
  • 61
    • 5144233898 scopus 로고    scopus 로고
    • A review of the mechanisms and role of monoamine oxidase inhibitors in Parkinson's disease
    • Youdim MB, Riederer PF 2004. A review of the mechanisms and role of monoamine oxidase inhibitors in Parkinson's disease. Neurology, 63:S32-5.
    • (2004) Neurology , vol.63
    • Youdim, M.B.1    Riederer, P.F.2
  • 62
    • 0036162584 scopus 로고    scopus 로고
    • Rat striatal monoamine oxidase-B inhibition by 1-deprenyl and rasagiline:its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease
    • Youdim MB, Tipton KF 2002. Rat striatal monoamine oxidase-B inhibition by 1-deprenyl and rasagiline:its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease. Parkinsonism Relat Disord, 8:247-53.
    • (2002) Parkinsonism Relat Disord , vol.8 , pp. 247-253
    • Youdim, M.B.1    Tipton, K.F.2
  • 63
    • 0034941767 scopus 로고    scopus 로고
    • The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition in cell culture and in vivo
    • Youdim MB, Wadia A, Tatton W, et al. 2001. The anti-Parkinson drug rasagiline and its cholinesterase inhibitor derivatives exert neuroprotection unrelated to MAO inhibition in cell culture and in vivo. Ann N Y Acad Sci, 939:450-8.
    • (2001) Ann N Y Acad Sci , vol.939 , pp. 450-458
    • Youdim, M.B.1    Wadia, A.2    Tatton, W.3
  • 64
    • 0035568344 scopus 로고    scopus 로고
    • Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]
    • Youdim MB, Weinstock M 2001. Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]. Cell Mol Neurobiol, 21:555-73.
    • (2001) Cell Mol Neurobiol , vol.21 , pp. 555-573
    • Youdim, M.B.1    Weinstock, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.