-
1
-
-
33646806089
-
The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon
-
doi:10.1242/jcs.02835. PMID:16537651
-
Ada-Nguema, A.S., Xenias, H., Hofman, J.M., Wiggins, C.H., Sheetz, M.P., and Keely, P.J. 2006. The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon. J. Cell Sci. 119(7): 1307-1319. doi:10.1242/jcs.02835. PMID:16537651.
-
(2006)
J. Cell Sci
, vol.119
, Issue.7
, pp. 1307-1319
-
-
Ada-Nguema, A.S.1
Xenias, H.2
Hofman, J.M.3
Wiggins, C.H.4
Sheetz, M.P.5
Keely, P.J.6
-
2
-
-
0033956710
-
Differential activation of mitogen-activated protein kinases in experimental mesangioproliferative glomerulonephritis
-
PMID:10665930
-
Bokemeyer, D., Ostendorf, T., Kunter, U., Lindemann, M., Kramer, H.J., and Floege, J. 2000. Differential activation of mitogen-activated protein kinases in experimental mesangioproliferative glomerulonephritis. J. Am. Soc. Nephrol. 11(2): 232-240. PMID:10665930.
-
(2000)
J. Am. Soc. Nephrol
, vol.11
, Issue.2
, pp. 232-240
-
-
Bokemeyer, D.1
Ostendorf, T.2
Kunter, U.3
Lindemann, M.4
Kramer, H.J.5
Floege, J.6
-
3
-
-
0034724873
-
The association of CRKII with C3G can be regulated by integrins and defines a novel means to regulate the mitogen-activated protein kinases
-
doi:10.1074/jbc.275.17. 13118. PMID:10777617
-
Buensuceso, C.S., and O'Toole, T.E. 2000. The association of CRKII with C3G can be regulated by integrins and defines a novel means to regulate the mitogen-activated protein kinases. J. Biol. Chem. 275(17): 13118-13125.doi:10.1074/jbc.275.17. 13118. PMID:10777617.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.17
, pp. 13118-13125
-
-
Buensuceso, C.S.1
O'Toole, T.E.2
-
4
-
-
0032861541
-
Pentoxifylline attenuates experimental mesangial proliferative glomerulonephritis
-
doi:10.1046/j.1523-1755.1999.00636.x. PMID:10469361
-
Chen, Y.M., Chien, C.T., Hu-Tsai, M.I., Wu, K.D., Tsai, C.C., Wu, M.S., and Tsai, T.J. 1999. Pentoxifylline attenuates experimental mesangial proliferative glomerulonephritis. Kidney Int. 56(3): 932-943. doi:10.1046/j.1523-1755.1999.00636.x. PMID:10469361.
-
(1999)
Kidney Int
, vol.56
, Issue.3
, pp. 932-943
-
-
Chen, Y.M.1
Chien, C.T.2
Hu-Tsai, M.I.3
Wu, K.D.4
Tsai, C.C.5
Wu, M.S.6
Tsai, T.J.7
-
5
-
-
0031551588
-
Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase
-
doi:10.1093/emboj/16.21.6439. PMID: 9351826
-
Foschi, M., Chari, S., Dunn, M.J., and Sorokin, A. 1997. Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase. EMBO J. 16(21): 6439-6451.doi:10.1093/emboj/16.21.6439. PMID: 9351826.
-
(1997)
EMBO J
, vol.16
, Issue.21
, pp. 6439-6451
-
-
Foschi, M.1
Chari, S.2
Dunn, M.J.3
Sorokin, A.4
-
6
-
-
0031014969
-
2+-mediated activation of Rap1 in human platelets
-
doi:10.1093/emboj/16.2.252. PMID:9029146
-
2+-mediated activation of Rap1 in human platelets. EMBO J. 16(2): 252-259. doi:10.1093/emboj/16.2.252. PMID:9029146.
-
(1997)
EMBO J
, vol.16
, Issue.2
, pp. 252-259
-
-
Franke, B.1
Akkerman, J.W.2
Bos, J.L.3
-
7
-
-
0029658588
-
An orally active ETA/ETB receptor antagonist ameliorates proteinuria and glomerular lesions in rats with proliferative nephritis
-
doi:10.1038/ki.1996.397. PMID:8872972
-
Gómez-Garre, D., Largo, R., Liu, X.H., Gutierrez, S., López-Armada, M.J., Palacios, I., and Egido, J. 1996. An orally active ETA/ETB receptor antagonist ameliorates proteinuria and glomerular lesions in rats with proliferative nephritis. Kidney Int. 50(3): 962-972. doi:10.1038/ki.1996.397. PMID:8872972.
-
(1996)
Kidney Int
, vol.50
, Issue.3
, pp. 962-972
-
-
Gómez-Garre, D.1
Largo, R.2
Liu, X.H.3
Gutierrez, S.4
López-Armada, M.J.5
Palacios, I.6
Egido, J.7
-
8
-
-
3042721497
-
Amplification, up-regulation and over-expression of C3G (CRK SH3 domain-binding guanine nucleotide-releasing factor) in non-small cell lung cancers
-
doi:10.1007/s10038-004-0148-1. PMID:15138850
-
Hirata, T., Nagai, H., Koizumi, K., Okino, K., Harada, A., Onda, M., et al. 2004. Amplification, up-regulation and over-expression of C3G (CRK SH3 domain-binding guanine nucleotide-releasing factor) in non-small cell lung cancers. J. Hum. Genet. 49(6): 290-295. doi:10.1007/s10038-004-0148-1. PMID:15138850.
-
(2004)
J. Hum. Genet
, vol.49
, Issue.6
, pp. 290-295
-
-
Hirata, T.1
Nagai, H.2
Koizumi, K.3
Okino, K.4
Harada, A.5
Onda, M.6
-
9
-
-
63649107261
-
RAPGEF1 gene variants associated with type 2 dia-betes in the Korean population
-
doi:10.1016/j.diabres.2009.02.019. PMID: 19297053
-
Hong, K.W., Jin, H.S., Lim, J.E., Ryu, H.J., Go, M.J., Lee, J.Y., et al. 2009. RAPGEF1 gene variants associated with type 2 dia-betes in the Korean population. Diabetes Res. Clin. Pract. 84(2): 117-122. doi:10.1016/j.diabres.2009.02.019. PMID: 19297053.
-
(2009)
Diabetes Res. Clin. Pract
, vol.84
, Issue.2
, pp. 117-122
-
-
Hong, K.W.1
Jin, H.S.2
Lim, J.E.3
Ryu, H.J.4
Go, M.J.5
Lee, J.Y.6
-
10
-
-
76749085229
-
Endothelin, hypertension and chronic kidney disease: New insights
-
doi:10.1097/MNH.0b013e328335f91f. PMID:20051851
-
Kohan, D.E. 2010. Endothelin, hypertension and chronic kidney disease: new insights. Curr. Opin. Nephrol. Hypertens. 19(2): 134-139. doi:10.1097/MNH.0b013e328335f91f. PMID:20051851.
-
(2010)
Curr. Opin. Nephrol. Hypertens
, vol.19
, Issue.2
, pp. 134-139
-
-
Kohan, D.E.1
-
11
-
-
64849092800
-
C3G silencing enhances STI-571-induced apoptosis in CML cells through p38 MAPK activation, but it antagonizes STI-571 inhibitory effect on survival
-
doi:10. 1016/j.cellsig.2009.03.015. PMID:19324082
-
Maia, V., Sanz, M., Gutierrez-Berzal, J., de Luis, A., Gutierrez-Uzquiza, A., Porras, A., and Guerrero, C. 2009. C3G silencing enhances STI-571-induced apoptosis in CML cells through p38 MAPK activation, but it antagonizes STI-571 inhibitory effect on survival. Cell. Signal. 21(7): 1229-1235. doi:10. 1016/j.cellsig.2009.03.015. PMID:19324082.
-
(2009)
Cell. Signal
, vol.21
, Issue.7
, pp. 1229-1235
-
-
Maia, V.1
Sanz, M.2
Gutierrez-Berzal, J.3
de Luis, A.4
Gutierrez-Uzquiza, A.5
Porras, A.6
Guerrero, C.7
-
12
-
-
0015387405
-
Isolation of glomeruli from mammalian kidneys by graded sieving
-
PMID: 5047603
-
Misra, R.P. 1972. Isolation of glomeruli from mammalian kidneys by graded sieving. Am. J. Clin. Pathol. 58(2): 135-139.PMID: 5047603.
-
(1972)
Am. J. Clin. Pathol
, vol.58
, Issue.2
, pp. 135-139
-
-
Misra, R.P.1
-
13
-
-
0036911338
-
Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells
-
doi:10.1091/mbc.E02-04-0181. PMID:12475948
-
Nagashima, K., Endo, A., Ogita, H., Kawana, A., Yamagishi, A., Kitabatake, A., et al. 2002. Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells. Mol. Biol. Cell, 13(12): 4231-4242. doi:10.1091/mbc.E02-04-0181. PMID:12475948.
-
(2002)
Mol. Biol. Cell
, vol.13
, Issue.12
, pp. 4231-4242
-
-
Nagashima, K.1
Endo, A.2
Ogita, H.3
Kawana, A.4
Yamagishi, A.5
Kitabatake, A.6
-
14
-
-
32144461352
-
Activation of Rap1, Cdc42, and rac by nectin adhesion system
-
doi:10.1016/S0076-6879(06)06030-7. PMID:16472674
-
Ogita, H., and Takai, Y. 2006. Activation of Rap1, Cdc42, and rac by nectin adhesion system. Methods Enzymol. 406: 415-424. doi:10.1016/S0076-6879(06)06030-7. PMID:16472674.
-
(2006)
Methods Enzymol
, vol.406
, pp. 415-424
-
-
Ogita, H.1
Takai, Y.2
-
15
-
-
17844363949
-
Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis
-
doi:10.1093/emboj/20.13.3333. PMID:11432821
-
Ohba, Y., Ikuta, K., Ogura, A., Matsuda, J., Mochizuki, N., Nagashima, K., et al. 2001. Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J. 20(13): 3333-3341. doi:10.1093/emboj/20.13.3333. PMID:11432821.
-
(2001)
EMBO J
, vol.20
, Issue.13
, pp. 3333-3341
-
-
Ohba, Y.1
Ikuta, K.2
Ogura, A.3
Matsuda, J.4
Mochizuki, N.5
Nagashima, K.6
-
16
-
-
33646037351
-
Inactivation of Crk SH3 domain-binding guanine nucleotide-releasing factor (C3G) in cervical squamous cell carcinoma
-
doi:10.1111/j.1525-1438.2006.00352.x. PMID: 16681758
-
Okino, K., Nagai, H., Nakayama, H., Doi, D., Yoneyama, K., Konishi, H., and Takeshita, T. 2006. Inactivation of Crk SH3 domain-binding guanine nucleotide-releasing factor (C3G) in cervical squamous cell carcinoma. Int. J. Gynecol. Cancer, 16(2): 763-771. doi:10.1111/j.1525-1438.2006.00352.x. PMID: 16681758.
-
(2006)
Int. J. Gynecol. Cancer
, vol.16
, Issue.2
, pp. 763-771
-
-
Okino, K.1
Nagai, H.2
Nakayama, H.3
Doi, D.4
Yoneyama, K.5
Konishi, H.6
Takeshita, T.7
-
17
-
-
66449105246
-
Specificity in Ras and Rap signaling
-
doi:10.1074/ jbc.R800061200. PMID:19091745
-
Raaijmakers, J.H., and Bos, J.L. 2009. Specificity in Ras and Rap signaling. J. Biol. Chem. 284(17): 10995-10999.doi:10.1074/ jbc.R800061200. PMID:19091745.
-
(2009)
J. Biol. Chem
, vol.284
, Issue.17
, pp. 10995-10999
-
-
Raaijmakers, J.H.1
Bos, J.L.2
-
18
-
-
55849087673
-
The guanine nucleotide exchange factor, C3G regulates differentiation and survival of human neuroblastoma cells
-
doi:10.1111/j.1471-4159.2008. 05710.x. PMID:18957052
-
Radha, V., Rajanna, A., Gupta, R.K., Dayma, K., and Raman, T. 2008. The guanine nucleotide exchange factor, C3G regulates differentiation and survival of human neuroblastoma cells. J. Neurochem. 107(5): 1424-1435.doi:10.1111/j.1471-4159.2008. 05710.x. PMID:18957052.
-
(2008)
J. Neurochem
, vol.107
, Issue.5
, pp. 1424-1435
-
-
Radha, V.1
Rajanna, A.2
Gupta, R.K.3
Dayma, K.4
Raman, T.5
-
19
-
-
22544457474
-
Down-regulation of Rap1 activity is involved in ephrinB1-induced cell contraction
-
doi:10.1042/BJ20050048. PMID:15725075
-
Riedl, J.A., Brandt, D.T., Batlle, E., Price, L.S., Clevers, H., and Bos, J.L. 2005. Down-regulation of Rap1 activity is involved in ephrinB1-induced cell contraction. Biochem. J. 389(2): 465-469. doi:10.1042/BJ20050048. PMID:15725075.
-
(2005)
Biochem. J
, vol.389
, Issue.2
, pp. 465-469
-
-
Riedl, J.A.1
Brandt, D.T.2
Batlle, E.3
Price, L.S.4
Clevers, H.5
Bos, J.L.6
-
20
-
-
33744927662
-
CrkII associates with BCAR3 in response to endothelin-1 in human glomerular mesangial cells
-
PMID:16740993
-
Rufanova, V.A., and Sorokin, A. 2006. CrkII associates with BCAR3 in response to endothelin-1 in human glomerular mesangial cells. Exp. Biol. Med. (Maywood), 231(6): 752-756. PMID:16740993.
-
(2006)
Exp. Biol. Med. (Maywood)
, vol.231
, Issue.6
, pp. 752-756
-
-
Rufanova, V.A.1
Sorokin, A.2
-
21
-
-
60849124225
-
Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading
-
doi:10.1002/jcp.21649. PMID:19086031
-
Rufanova, V.A., Alexanian, A., Wakatsuki, T., Lerner, A., and Sorokin, A. 2009a. Pyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreading. J. Cell. Physiol. 219(1): 45-56. doi:10.1002/jcp.21649. PMID:19086031.
-
(2009)
J. Cell. Physiol
, vol.219
, Issue.1
, pp. 45-56
-
-
Rufanova, V.A.1
Alexanian, A.2
Wakatsuki, T.3
Lerner, A.4
Sorokin, A.5
-
22
-
-
58049202236
-
C3G overexpression in glomerular epithelial cells during anti-GBM-induced glomerulonephritis
-
doi:10.1038/ki.2008.448. PMID:18784646
-
Rufanova, V.A., Lianos, E., Alexanian, A., Sorokina, E., Sharma, M., McGinty, A., and Sorokin, A. 2009b. C3G overexpression in glomerular epithelial cells during anti-GBM-induced glomerulonephritis. Kidney Int. 75(1): 31-40.doi:10.1038/ki.2008.448. PMID:18784646.
-
(2009)
Kidney Int
, vol.75
, Issue.1
, pp. 31-40
-
-
Rufanova, V.A.1
Lianos, E.2
Alexanian, A.3
Sorokina, E.4
Sharma, M.5
McGinty, A.6
Sorokin, A.7
-
23
-
-
0036161707
-
PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1
-
doi:10.1016/S1097-2765(01)00432-4. PMID:11804588
-
Schmitt, J.M., and Stork, P.J. 2002. PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1. Mol. Cell, 9(1): 85-94. doi:10.1016/S1097-2765(01)00432-4. PMID:11804588.
-
(2002)
Mol. Cell
, vol.9
, Issue.1
, pp. 85-94
-
-
Schmitt, J.M.1
Stork, P.J.2
-
24
-
-
0141813519
-
Physiology and pathology of endothelin-1 in renal mesangium
-
PMID:12954590
-
Sorokin, A., and Kohan, D.E. 2003. Physiology and pathology of endothelin-1 in renal mesangium. Am. J. Physiol. Renal Physiol. 285(4): F579-F589. PMID:12954590.
-
(2003)
Am. J. Physiol. Renal Physiol
, vol.285
, Issue.4
-
-
Sorokin, A.1
Kohan, D.E.2
-
25
-
-
27644475483
-
Multiple roles of Rap1 in hematopoietic cells: Complementary versus antagonistic functions
-
doi:10.1182/blood-2005-03-1062. PMID:16076873
-
Stork, P.J., and Dillon, T.J. 2005. Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions. Blood, 106(9): 2952-2961. doi:10.1182/blood-2005-03-1062. PMID:16076873.
-
(2005)
Blood
, vol.106
, Issue.9
, pp. 2952-2961
-
-
Stork, P.J.1
Dillon, T.J.2
-
26
-
-
44449172648
-
Sequential activation of Rap1and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells
-
doi:10.1111/j.13652443.2008.01187.x. PMID:18422604
-
Takahashi, M., Rikitake, Y., Nagamatsu, Y., Hara, T., Ikeda, W., Hirata, K., and Takai, Y. 2008. Sequential activation of Rap1and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells. Genes Cells, 13(6): 549-569.doi:10.1111/j.13652443.2008.01187.x. PMID:18422604.
-
(2008)
Genes Cells
, vol.13
, Issue.6
, pp. 549-569
-
-
Takahashi, M.1
Rikitake, Y.2
Nagamatsu, Y.3
Hara, T.4
Ikeda, W.5
Hirata, K.6
Takai, Y.7
-
27
-
-
0037262297
-
The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation
-
doi:10.1242/dev.00217. PMID:12466202
-
Voss, A.K., Gruss, P., and Thomas, T. 2003. The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation. Development, 130(2): 355-367. doi:10.1242/dev.00217. PMID:12466202.
-
(2003)
Development
, vol.130
, Issue.2
, pp. 355-367
-
-
Voss, A.K.1
Gruss, P.2
Thomas, T.3
-
28
-
-
0032227459
-
The role for endothelin in mesangial proliferative glomerulonephritis
-
PMID:10806841
-
Wu, H., Wang, H., Wang, Y., Liu, T., and Kuang, Y. 1998. The role for endothelin in mesangial proliferative glomerulonephritis. J. Tongji Med. Univ. 18(2): 122-125. PMID:10806841.
-
(1998)
J. Tongji Med. Univ
, vol.18
, Issue.2
, pp. 122-125
-
-
Wu, H.1
Wang, H.2
Wang, Y.3
Liu, T.4
Kuang, Y.5
-
29
-
-
0023616668
-
Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat
-
doi:10.1038/ki.1987.240. PMID: 2892961
-
Yamamoto, T., and Wilson, C.B. 1987. Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int. 32(4): 514-525. doi:10.1038/ki.1987.240. PMID: 2892961.
-
(1987)
Kidney Int
, vol.32
, Issue.4
, pp. 514-525
-
-
Yamamoto, T.1
Wilson, C.B.2
-
30
-
-
58149395046
-
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats
-
doi:10.1161/HYPERTENSIONAHA.108.115675. PMID:19029489
-
Yi, F., Xia, M., Li, N., Zhang, C., Tang, L., and Li, P.L. 2009. Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats. Hypertension, 53(1): 90-96.doi:10.1161/HYPERTENSIONAHA.108.115675. PMID:19029489.
-
(2009)
Hypertension
, vol.53
, Issue.1
, pp. 90-96
-
-
Yi, F.1
Xia, M.2
Li, N.3
Zhang, C.4
Tang, L.5
Li, P.L.6
|