Inactivation of Crk SH3 domain-binding guanine nucleotide-releasing factor (C3G) in cervical squamous cell carcinoma

International Journal of Gynecological Cancer

Volumn 16, Issue 2, 2006, Pages 763-771

  Okino, K ^a   Nagai, H ^a   Nakayama, H ^b   Doi, D ^a   Yoneyama, K ^a   Konishi, H ^a   Takeshita, T ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b KANAGAWA CANCER CENTER   (Japan)

Author keywords

C3G; HPV; Human cervical cancer; siRNA

Indexed keywords

ADAPTOR PROTEIN; COMPLEMENTARY DNA; CRK LIKE PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN C3G; PROTEIN SH3; RAP1 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; C3G GENE; CHROMOSOME 9Q; CLINICAL ARTICLE; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE INACTIVATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; UTERINE CERVIX CARCINOMA; VIRUS INFECTION; WART VIRUS;

ADULT; AGED; CARCINOMA, SQUAMOUS CELL; DNA METHYLATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE NUCLEOTIDE-RELEASING FACTOR 2; HUMANS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; RNA, SMALL INTERFERING; UTERINE CERVICAL NEOPLASMS;

EID: 33646037351     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1111/j.1525-1438.2006.00352.x     Document Type: Article

References (34)

1. Barnard P Payne E McMillan NA The human papillomavirus E7 protein is able to inhibit the antiviral and anti-growth functions of interferon-alpha Virology 2000 277 411 9
2. zur Hausen H Human papillomaviruses in the pathogenesis of anogenital cancer Virology 1991 184 9 13
3. Nees M Geoghegan JM Hyman T Frank S Miller L Woodworth CD Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappa B-responsive genes in cervical keratinocytes J Virol 2001 75 4283 96
4. Campbell SL Khosravi-Far R Rossman KL Clark GJ Der CJ Increasing complexity of Ras signaling Oncogene 1998 17 1395 413
5. Downward J Regulation of p21ras by GTPase activating proteins and guanine nucleotide exchange proteins Curr Opin Genet Dev 1992 2 13 8
6. Bourne HR Sanders DA McCormick F The GTPase superfamily: a conserved switch for diverse cell functions Nature 1990 348 125 32
7. Tanaka S Morishita T Hashimoto Y et al C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and CRB2/ASH proteins Proc Natl Acad Sci U S A 1994 91 3443 7
8. Knudsen BS Feller SM Hanafusa H Four praline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk J Biol Chem 1994 269 32781 7
9. Ohba Y Mochizuki N Matsuo K et al Rap2 as a slowly responding molecular switch in the rap1 signaling cascade Mol Cell Biol 2000 20 6047 83
10. Vossler MR Yao H York RD Pan MG Rim CS Stork PJ cAMP activates MAP kinase and Elk-1 through a B-Raf and Rap1-dependent pathway Cell 1997 89 73 82
11. York RD Yao H Dillon T et al Rap1 mediates sustained MAP kinase activation induced by neuro growth factor Nature 1998 392 622 6
12. Ohba Y Ikuta K Ogura A et al Requirement for C3G dependent Rap1 activation for cell adhesion and embryogenesis Euro Mol Biol Organ 2001 20 3333 41
13. Tanaka S Ouchi T Hanafusa H Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G Proc Natl Acad Sci U S A 1997 94 2356 61
14. Kitamura Y Minobe K Nakata T et al Ret/ PTC3 is the most frequent form of gene rearrangement in papillary thyroid carcinoma in Japan J Hum Genet 1999 44 96 102
15. Koyama M Nagai H Bando K Ito M Moriyama Y Emi M Localization of a target region of allelic loss to a 1-cM interval on chromosome 16p13.13 in hepatocellular carcinoma Jpn J Cancer Res 1999 90 951 6
16. Bando K Nagai H Matsumoto S et al Identification of a 1-cM resion of common deletion on 4q35 associated with progression of hepatocellular carcinoma Genes Chromosomes Cancer 1999 25 284 9
17. Tsukamoto K Haruta K Shiba T Emi M Isolation and mapping of a polymorphic CA repeat sequence at the human interleukin 6 locus J Hum Genet 1998 43 71 2
18. Jone PA Laird PW Cancer epigenetics comes of age Nat Genet 1999 21 163 7
19. Sato M Mori Y Sakurada A Fujiwara S Horii A The H-cadherin(CDH13) gene is inactivated I human lung cancer Hum Genet 1998 103 96 101
20. Iwata N Yamamoto H Sasaki S et al Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma Oncogene 2000 2 19 5298 302
21. Smith AE Slepchenko BM Schaff JC Loew LM Macara IG Systems analysis of Ran transport Science 2002 295 488 91
22. Drivas GT Shih A Coutavas E Rush MG D'Eustachio P Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line Mol Cell Biol 1990 10 1793 7
23. Sehgal A Keener C Boynton AL et al Isolation and characterization of a novel gene from human glioblastoma multiforme tumor tissue Int J Cancer 1997 71 565 72
24. Bush J Temesvari L Rodriguez-Paris J Buczynski G Cardelli J A role for a Rab4-like GTPase in endocytosis and in regulation of contractile vacuole structure and function in Dictyostelium discoideum Mol Biol Cell 1996 7 1623 38
25. Kleijnen MF Shih AH Zhou P et al The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome Mol Cell 2000 6 409 19
26. Yabana N Shibuya M Bernier-Villamor V Sampson DA Matunis MJ Lima CD Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1 Cell 2002 108 345 56
27. Guazzi S Price M De Felice M et al Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity EMBO J 1990 9 3631 9
28. Acebron A Aza-Blanc P Rossi DL Lamas L Santisteban P Congenital human thyroglobulin defect due to low expression of the thyroid-specific transcription factor TTF-1 J Clin Invest 1995 96 781 5
29. Breedveld GJ van Dongen JWF Danesino C et al Mutations in TITF-1 are associated with benign hereditary chorea Hum Mol Genet 2002 11 971 9
30. Kimura S Hara Y Pineau T et al The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary Genes Dev 1996 10 60 9
31. De Smaele E Zazzeroni F Papa S et al Induction of gadd45-beta by NF-kappa-B downregulates pro-apoptotic JNK signaling Nature 2001 414 308 13
32. Brenner DA O'Hara M Angel P Chojkier M Karin M Prolonged activation of JUN and collagenase genes by tumour necrosis factor-alpha Nature 1989 337 661 3
33. Yabana N Shibuya M Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity Oncogene 2002 21 7720 9
34. Ng CC Koyama K Okamura S Kondoh H Takei Y Nakamura Y Isolation and characterization of a novel TP53-inducible gene, TP53TG3 Genes Chromosomes Cancer 1999 26 329 35