Activation of Rap1, Cdc42, and Rac by nectin adhesion system

Methods in Enzymology

Volumn 406, Issue , 2006, Pages 415-424

  Ogita, Hisakazu ^a   Takai, Yoshimi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; NECTIN; PROTEIN CDC42; RAC PROTEIN; RAP1 PROTEIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL SPREADING; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION;

ANIMALIA;

EID: 32144461352     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(06)06030-7     Document Type: Review

References (14)

1. Fukuhara T., Shimizu K., Kawakatsu T., Fukuyama T., Minami Y., Honda T., Hoshino T., Yamada T., Ogita H., Okada M., and Takai Y. Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG J. Cell Biol. 166 2004 393 405
2. Fukuyama T., Ogita H., Kawakatsu T., Fukuhara T., Yamada T., Sato T., Shimizu K., Nakamura T., Matsuda M., and Takai Y. Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions J. Biol. Chem. 280 2005 815 825
3. Honda T., Shimizu K., Kawakatsu T., Fukuhara A., Irie K., Nakamura T., Matsuda M., and Takai Y. Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts Genes Cells 8 2003 481 491
4. Kawakatsu T., Ogita H., Fukuhara T., Fukuyama T., Minami Y., Shimizu K., and Takai Y. Vav2 as a Rac-GDP/GTP Exchange Factor Responsible for the Nectin-induced, c-Src-and Cdc42-mediated Activation of Rac J. Biol. Chem. 280 2005 4940 4947
5. Kawakatsu T., Shimizu K., Honda T., Fukuhara T., Hoshino T., and Takai Y. trans-Interactions of nectins induce formation of filopodia and lamellipodia through the respective activation of Cdc42 and Rac small G proteins J. Biol. Chem. 277 2002 50749 50755
6. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
7. Nagafuchi A., Takeichi M., and Tsukita S. The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression Cell 65 1991 849 857
8. Niwa H., Yamamura K., and Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector Gene 108 1991 193 199
9. Sakisaka T., and Takai Y. Biology and pathology of nectins and nectin-like molecules Curr. Opin. Cell Biol. 16 2004 513 521
10. Satoh-Horikawa K., Nakanishi H., Takahashi K., Miyahara M., Nishimura M., Tachibana K., Mizoguchi A., and Takai Y. Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities J. Biol. Chem. 275 2000 10291 10299
11. Takahashi K., Nakanishi H., Miyahara M., Mandai K., Satoh K., Satoh A., Nishioka H., Aoki J., Nomoto A., Mizoguchi A., and Takai Y. Nectin/PRR: An immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein J. Cell Biol. 145 1999 539 549
12. Takai Y., Irie K., Shimizu K., Sakisaka T., and Ikeda W. Nectins and nectin-like molecules: Roles in cell adhesion, migration, and polarization Cancer Sci. 94 2003 655 667
13. Takai Y., and Nakanishi H. Nectin and afadin: Novel organizers of intercellular junctions J. Cell Sci. 116 2003 17 27
14. Tessier D.C., Thomas D.Y., Khouri H.E., Laliberte F., and Vernet T. Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide Gene 98 1991 177 183