C3G silencing enhances STI-571-induced apoptosis in CML cells through p38 MAPK activation, but it antagonizes STI-571 inhibitory effect on survival

Cellular Signalling

Volumn 21, Issue 7, 2009, Pages 1229-1235

  Maia, Vera ^a   Sanz, María ^a   Gutierrez Berzal, Javier ^a   de Luis, Alberto ^a   Gutierrez Uzquiza, Alvaro ^b   Porras, Almudena ^b   Guerrero, Carmen ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Apoptosis; C3G; CML; p38 MAPK; STI 571

Indexed keywords

IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; RAP1 PROTEIN; RNA;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL SURVIVAL; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; GENE EXPRESSION; PRIORITY JOURNAL; RNA INTERFERENCE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SURVIVAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GUANINE NUCLEOTIDE-RELEASING FACTOR 2; HUMANS; IMMUNOBLOTTING; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PIPERAZINES; PYRIMIDINES; RAP1 GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 64849092800     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2009.03.015     Document Type: Article

References (32)

1. Gotoh T., Hattori S., Nakamura S., Kitayama H., Noda M., Takai Y., Kaibuchi K., Matsui H., Hatase O., Takahashi H., et al. Mol. Cell. Biol. 15 (1995) 6746
2. Gotoh T., Niino Y., Tokuda M., Hatase O., Nakamura S., Matsuda M., and Hattori S. J. Biol. Chem. 272 (1997) 18602
3. Ohba Y., Ikuta K., Ogura A., Matsuda J., Mochizuki N., Nagashima K., Kurokawa K., Mayer B.J., Maki K., Miyazaki J., and Matsuda M. EMBO J. 20 (2001) 3333
4. Guerrero C., Fernandez-Medarde A., Rojas J.M., Font de Mora J., Esteban L.M., and Santos E. Oncogene 16 (1998) 613
5. Guerrero C., Martin-Encabo S., Fernandez-Medarde A., and Santos E. Oncogene 23 (2004) 4885
6. Martin-Encabo S., Santos E., and Guerrero C. Exp. Cell Res. 313 (2007) 3881
7. Shivakrupa R., Radha V., Sudhakar C., and Swarup G. J. Biol. Chem. 278 (2003) 52188
8. Gutierrez-Berzal J., Castellano E., Martin-Encabo S., Gutierrez-Cianca N., Hernandez J.M., Santos E., and Guerrero C. Exp. Cell Res. 312 (2006) 938
9. Nebreda A.R., and Porras A. Trends Biochem. Sci. 25 (2000) 257
10. Cuenda A., and Rousseau S. Biochim. Biophys. Acta 1773 (2007) 1358
11. Hui L., Bakiri L., Stepniak E., and Wagner E.F. Cell Cycle 6 (2007) 2429
12. Porras A., Zuluaga S., Black E., Valladares A., Alvarez A.M., Ambrosino C., Benito M., and Nebreda A.R. Mol. Biol. Cell 15 (2004) 922
13. Steelman L.S., Pohnert S.C., Shelton J.G., Franklin R.A., Bertrand F.E., and McCubrey J.A. Leukemia 18 (2004) 189
14. Jacquel A., Herrant M., Legros L., Belhacene N., Luciano F., Pages G., Hofman P., and Auberger P. FASEB J. 17 (2003) 2160
15. Jacquel A., Colosetti P., Grosso S., Belhacene N., Puissant A., Marchetti S., Breittmayer J.P., and Auberger P. Oncogene 26 (2007) 2445
16. Galan-Moya E.M., Hernandez-Losa J., Aceves Luquero C.I., de la Cruz-Morcillo M.A., Ramírez-Castillejo C., Callejas-Valera J.L., Arriaga A., Aranburo A.F., Ramón y Cajal S., Silvio Gutkind J., and Sánchez-Prieto R. Int. J. Cancer 122 (2008) 289
17. Parmar S., Katsoulidis E., Verma A., Li Y., Sassano A., Lal L., Majchrzak B., Ravandi F., Tallman M.S., Fish E.N., and Platanias L.C. J. Biol. Chem. 279 (2004) 25345
18. Kohmura K., Miyakawa Y., Kawai Y., Ikeda Y., and Kizaki M. J. Cell. Physiol. 198 (2004) 370
19. Stork P.J., and Dillon T.J. Blood 106 (2005) 2952
20. Di Fiore P.P., Pierce J.H., Kraus M.H., Segatto O., King C.R., and Aaronson S.A. Science 237 (1987) 178
21. Irizarry R.A., Hobbs B., Collin F., Beazer-Barclay Y.D., Antonellis K.J., Scherf U., and Speed T.P. Biostatistics 4 (2003) 249
22. Tusher V.G., Tibshirani R., and Chu G. Proc. Natl. Acad. Sci. U S A 98 (2001) 5116
23. Voss A.K., Krebs D.L., and Thomas T. EMBO J. 25 (2006) 3652
24. Liu Q., and Hofmann P.A. Am. J. Physiol. Heart Circ. Physiol. 286 (2004) H2204
25. Zuluaga S., Alvarez-Barrientos A., Gutierrez-Uzquiza A., Benito M., Nebreda A.R., and Porras A. Cell. Signal. 19 (2007) 62
26. Al-Shahrour F., Diaz-Uriarte R., and Dopazo J. Bioinformatics 20 (2004) 578
27. Parmar S., and Platanias L.C. Curr. Opin. Oncol. 15 (2003) 431
28. Yu C., Krystal G., Varticovksi L., McKinstry R., Rahmani M., Dent P., and Grant S. Cancer Res. 62 (2002) 188
29. Mizuchi D., Kurosu T., Kida A., Jin Z.H., Jin A., Arai A., and Miura O. Biochem. Biophys. Res. Commun. 326 (2005) 645
30. Jin A., Kurosu T., Tsuji K., Mizuchi D., Arai A., Fujita H., Hattori M., Minato N., and Miura O. Oncogene 25 (2006) 4332
31. Hattori M., and Minato N. J. Biochem. 134 (2003) 479
32. Ishida D., Kometani K., Yang H., Kakugawa K., Masuda K., Iwai K., Suzuki M., Itohara S., Nakahata T., Hiai H., Kawamoto H., Hattori M., and Minato N. Cancer Cell 4 (2003) 55