Biphasic activation of p21(ras) by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase

EMBO Journal

Volumn 16, Issue 21, 1997, Pages 6439-6451

  Foschi, Marco ^a,b   Chari, Sunita ^c   Dunn, Michael J ^a   Sorokin, Andrey ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF FLORENCE   (Italy)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adaptor proteins; Adenovirus mediated gene transfer; Desensitization; MKP 1; Sos phosphorylation

Indexed keywords

ENDOTHELIN 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE; PROTEIN P21; 3CH134 PROTEIN; CELL CYCLE PROTEIN; ENDOTHELIN RECEPTOR; GRB2 PROTEIN, RAT; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; HYBRID PROTEIN; IMMEDIATE EARLY PROTEIN; PROTEIN; PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SRC HOMOLOGY 2 DOMAIN CONTAINING, TRANSFORMING PROTEIN 1; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; MESANGIUM; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; VIRUS RECOMBINANT; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; DRUG EFFECT; ENZYMOLOGY; KINETICS; MALE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; SPRAGUE DAWLEY RAT;

ADENOVIRIDAE; ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL CYCLE PROTEINS; CELLS, CULTURED; ENDOTHELIN-1; ENZYME ACTIVATION; GLOMERULAR MESANGIUM; GRB2 ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; IMMEDIATE-EARLY PROTEINS; KINETICS; MALE; MODELS, BIOLOGICAL; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; PROTO-ONCOGENE PROTEINS P21(RAS); RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 0031551588     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.21.6439     Document Type: Article

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