Transgenic Models

Encyclopedia of Respiratory Medicine, Four-Volume Set

Volumn , Issue , 2006, Pages 283-287

  Lee, C G ^a   Elias, J A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Asthma; COPD; Inducible overexpressing; Lung cancer; Pulmonary fibrosis; Transgenic mice

Indexed keywords

EID: 78650015441     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B0-12-370879-6/00396-3     Document Type: Chapter

References (15)

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2. Elias J.A., Lee C.G., Zheng T., et al. New insights into the pathogenesis of asthma. Journal of Clinical Investigation 2003, 111:291-297.
3. Homer R.J., Elias J.A. Airway remodeling in asthma. therapeutic implications of mechanisms. Physiology (Bethesda) 2005, 20:28-35.
4. Kwak I., Tsai S.Y., DeMayo F.J. Genetically engineered mouse models for lung cancer. Annual Review of Physiology 2004, 66:647-663.
5. Lee C.G., Cho S.J., Kang M.J., et al. Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. Journal of Experimental Medicine 2004, 200:377-389.
6. Lee C.G., Link H., Baluk P., et al. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nature Medicine 2004, 10:1095-1103.
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9. Vasquez Y.R., Spina D. What have transgenic and knockout animals taught us about respiratory disease?. Respiratory Research 2000, 1:82-86.
10. Vicencio A.G., Lee C.G., Cho S.J., et al. Conditional overexpression of bioactive transforming growth factor-beta1 in neonatal mouse lung. a new model for bronchopulmonary dysplasia?. American Journal of Respiratory Cell and Molecular Biology 2004, 31:650-656.
11. Whitsett J.A., Glasser S.W., Tichelaar J.W., et al. Transgenic models for study of lung morphogenesis and repair. Parker B. Francis lecture. Chest 2001, 120:27S-30S.
12. Zhao B., Magdaleno S., Chua S., et al. Transgenic mouse models for lung cancer. Experimental Lung Research 2000, 26:567-579.
13. Zheng T., Zhu Z., Wang Z., et al. Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. Journal of Clinical Investigation 2000, 106:1081-1093.
14. Zhu Z., Lee C.G., Zheng T., et al. Airway inflammation and remodeling in asthma lessons from interleukin 11 and interleukin 13 transgenic mice. American Journal of Respiratory and Critical Care Medicine 2001, 164:S67-1370.
15. Zhu Z., Zheng T., Lee C.G., et al. Tetracycline-controlled transcriptional regulation systems. advances and application in transgenic animal modeling. Seminars in Cell and Developmental Biology 2002, 13:121-128.