Adipose-derived mesenchymal stem cells protect PC12 cells from glutamate excitotoxicity-induced apoptosis by upregulation of XIAP through PI3-K/Akt activation

Toxicology

Volumn 279, Issue 1-3, 2011, Pages 189-195

  Lu, Shan ^a   Lu, Chunhua ^a   Han, Qin ^a   Li, Jing ^a   Du, Zhijian ^a   Liao, Lianming ^a   Zhao, Robert Chunhua ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Adipose derived mesenchymal stem cell; Caspase 3 activity; Excitotoxicity; Neuroprotection; PI3 K Akt pathway; XIAP

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; GLUTAMIC ACID; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SCATTER FACTOR; VASCULOTROPIN; X LINKED INHIBITOR OF APOPTOSIS;

ADIPOSE DERIVED MESENCHYMAL STEM CELL; ARTICLE; CELL PROTECTION; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME METABOLISM; ENZYME REGULATION; EXCITOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; STEM CELL; UPREGULATION; WESTERN BLOTTING;

ADIPOSE TISSUE; ANIMALS; APOPTOSIS; CASPASE 3; CELL SURVIVAL; GLUTAMIC ACID; IN SITU NICK-END LABELING; MESENCHYMAL STEM CELLS; NERVE GROWTH FACTORS; PC12 CELLS; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; UP-REGULATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 78650019181     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.10.011     Document Type: Article

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