Inhibition of apoptosis-inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons

Journal of Neurochemistry

Volumn 95, Issue 5, 2005, Pages 1277-1286

  Ishihara, Naoko ^a   Takagi, Norio ^a   Niimura, Makiko ^a   Takagi, Keiko ^a   Nakano, Midori ^a   Tanonaka, Kouichi ^a   Funakoshi, Hiroshi ^b   Matsumoto, Kunio ^b   Nakamura, Toshikazu ^b   Takeo, Satoshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis inducing factor; Hepatocyte growth factor; N methyl D aspartate receptor; Neuronal cell death

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; IONOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SCATTER FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME ACTIVITY; EXCITOTOXICITY; HIPPOCAMPUS; HUMAN; MITOCHONDRION; NERVE CELL CULTURE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RECEPTOR UPREGULATION;

ANIMALS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTE GROWTH FACTOR; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; N-METHYLASPARTATE; NEURONS; NEUROTOXINS; PHOSPHOPYRUVATE HYDRATASE; POLY ADENOSINE DIPHOSPHATE RIBOSE; PREGNANCY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-MET; RATS; RECOMBINANT PROTEINS; TIME FACTORS;

ANIMALIA;

EID: 28844472111     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03446.x     Document Type: Article

References (48)

1. Achim C. L., Katyal S., Wiley C. A., Shiratori M., Wang G., Oshika E., Petersen B. E., Li J. M. and Michalopoulos G. K. (1997) Expression of HGF and cMet in the developing and adult brain. Brain Res. Dev. Brain Res. 102, 299-303.
2. Balkovetz D. F. and Lipschutz J. H. (1999) Hepatocyte growth factor and the kidney: it is not just for the liver. Int. Rev. Cytol. 186, 225-260.
3. Bottaro D. P., Rubin J. S., Faletto D. L., Chan A. M., Kmiecik T. E., Vande Woude G. F. and Aaronson S. A. (1991) Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 251, 802-804.
4. Budd S. L., Tenneti L., Lishnak T. and Lipton S. A. (2000) Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons. Proc. Natl Acad. Sci. USA 97, 6161-6166.
5. Cande C., Cecconi F., Dessen P. and Kroemer G. (2002) Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J. Cell Sci. 115, 4727-4734.
6. Cheung E. C., Melanson-Drapeau L., Cregan S. P., Vanderluit J. L., Ferguson K. L., McIntosh W. C., Park D. S., Bennett S. A. and Slack R. S. (2005) Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. J. Neurosci. 25, 1324-1334.
7. Cregan S. P., Dawson V. L. and Slack R. S. (2004) Role of AIF in caspase-dependent and caspase-independent cell death. Oncogene 23, 2785-2796.
8. Dale N. and Roberts A. (1985) Dual-component amino-acid-mediated synaptic potentials: excitatory drive for swimming in Xenopus embryos. J. Physiol. 363, 35-59.
9. Danial N. N. and Korsmeyer S. J. (2004) Cell death: critical control points. Cell 116, 205-219.
10. Date I., Takagi N., Takagi K., Kago T., Matsumoto K., Nakamura T. and Takeo S. (2004) Hepatocyte growth factor improved learning and memory dysfunction of microsphere-embolized rats. J. Neurosci. Res. 78, 442-453.
11. Deveraux Q. L., Leo E., Stennicke H. R., Welsh K., Salvesen G. S. and Reed J. C. (1999) Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases. EMBO J. 18, 5242-5251.
12. Dingledine R., Borges K., Bowie D. and Traynelis S. F. (1999) The glutamate receptor ion channels. Pharmacol. Rev. 51, 7-61.
13. Gutierrez H., Dolcet X., Tolcos M. and Davies A. (2004) HGF regulates the development of cortical pyramidal dendrites. Development 131, 3717-3726.
14. Hamanoue M., Takemoto N., Matsumoto K., Nakamura T., Nakajima K. and Kohsaka S. (1996) Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro. J. Neurosci. Res. 43, 554-564.
15. Hayashi K., Morishita R., Nakagami H., Yoshimura S., Hara A., Matsumoto K., Nakamura T., Ogihara T., Kaneda Y. and Sakai N. (2001) Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons. Gene Ther. 8, 1167-1173.
16. Higuchi O. and Nakamura T. (1991) Identification and change in the receptor for hepatocyte growth factor in rat liver after partial hepatectomy or induced hepatitis. Biochem. Biophys. Res. Commun. 176, 599-607.
17. Honda S., Kagoshima M., Wanaka A., Tohyama M., Matsumoto K. and Nakamura T. (1995) Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: implication as neurotrophic factor. Brain Res. Mol. Brain Res. 32, 197-210.
18. Hossain M. A., Russell J. C., Gomez R., Laterra J. and Gomes R. (2002) Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent. J. Neurochem. 81, 365-378.
19. Huettner J. E. and Baughman R. W. (1986) Primary culture of identified neurons from the visual cortex of postnatal rats. J. Neurosci. 6, 3044-3060.
20. Keane R. W., Kraydieh S., Lotocki G., Alonso O. F., Aldana P. and Dietrich W. D. (2001) Apoptotic and antiapoptotic mechanisms after traumatic brain injury. J. Cereb. Blood Flow Metab. 21, 1189-1198.
21. Klein J. A., Longo-Guess C. M., Rossmann M. P., Seburn K. L., Hurd R. E., Frankel W. N., Bronson R. T. and Ackerman S. L. (2002) The harlequin mouse mutation downregulates apoptosis-inducing factor. Nature 419, 367-374.
22. Korhonen L., Sjoholm U., Takei N., Kern M. A., Schirmacher P., Castren E. and Lindholm D. (2000) Expression of c-Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D-expressing neurons. Eur. J. Neurosci. 12, 3453-3461.
23. Lorenzo H. K., Susin S. A., Penninger J. and Kroemer G. (1999) Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death. Cell Death Differ. 6, 516-524.
24. Machide M., Kamitori K., Nakamura Y. and Kohsaka S. (1998) Selective activation of phospholipase C gamma1 and distinct protein kinase C subspecies in intracellular signaling by hepatocyte growth factor/scatter factor in primary cultured rat neocortical cells. J. Neurochem. 71, 592-602.
25. Mandir A. S., Poitras M. F., Berliner A. R., Herring W. J., Guastella D. B., Feldman A., Poirier G. G., Wang Z. Q., Dawson T. M. and Dawson V. L. (2000) NMDA but not non-NMDA excitotoxicity is mediated by Poly (ADP-ribose) polymerase. J. Neurosci. 20, 8005-8011.
26. Matsumoto K. and Nakamura T. (1996) Emerging multipotent aspects of hepatocyte growth factor. J. Biochem. 119, 591-600.
27. Matsumoto K. and Nakamura T. (2001) Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases. Kidney Int. 59, 2023-2038.
28. McInnis J., Wang C., Anastasio N., Hultman M., Ye Y., Salvemini D. and Johnson K. M. (2002) The role of superoxide and nuclear factor-kappaB signaling in N-methyl-D-aspartate-induced necrosis and apoptosis. J. Pharmacol. Exp. Ther. 301, 478-487.
29. Miyazawa T., Matsumoto K., Ohmichi H., Katoh H., Yamashima T. and Nakamura T. (1998) Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: a novel neurotrophic factor. J. Cereb. Blood Flow Metab. 18, 345-348.
30. Nakamura T., Nawa K. and Ichihara A. (1984) Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem. Biophys. Res. Commun. 122, 1450-1459.
31. Nakamura T., Nishizawa T., Hagiya M., Seki T., Shimonishi M., Sugimura A., Tashiro K. and Shimizu S. (1989) Molecular cloning and expression of human hepatocyte growth factor. Nature 342, 440-443.
32. Nakamura T., Mizuno S., Matsumoto K., Sawa Y., Matsuda H. and Nakamura T. (2000) Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J. Clin. Invest. 106, 1511-1519.
33. Okamoto S., Li Z., Ju C., Scholzke M. N., Mathews E., Cui J., Salvesen G. S., Bossy-Wetzel E. and Lipton S. A. (2002) Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis. Proc. Natl Acad. Sci. USA 99, 3974-3979.
34. Silke J. and Vaux D. L. (2001) Two kinds of BIR-containing protein - inhibitors of apoptosis, or required for mitosis. J. Cell Sci. 114, 1821-1827.
35. Shimamura M., Sato N., Oshima K., Aoki M., Kurinami H., Waguri S., Uchiyama Y., Ogihara T., Kaneda Y. and Morishita R. (2004) Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model. Circulation 109, 424-431.
36. Sun W., Funakoshi H. and Nakamura T. (2002a) Localization and functional role of hepatocyte growth factor (HGF) and its receptor c-met in the rat developing cerebral cortex. Mol. Brain Res. 103, 36-48.
37. Sun W., Funakoshi H. and Nakamura T. (2002b) Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J. Neurosci. 22, 6537-6548.
38. Susin S. A., Lorenzo H. K., Zamzami N. et al. (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397, 441-446.
39. Tenneti L. and Lipton S. A. (2000) Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. J. Neurochem. 74, 134-142.
40. Thompson J., Dolcet X., Hilton M., Tolcos M. and Davies A. M. (2004) HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms. Mol. Cell Neurosci. 27, 441-452.
41. Tsuzuki N., Miyazawa T., Matsumoto K., Nakamura T. and Shima K. (2001) Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats. Neurol. Res. 23, 417-424.
42. Ueda H., Nakamura T., Matsumoto K., Sawa Y., Matsuda H. and Nakamura T. (2001) A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats. Cardiovasc. Res. 51, 41-50.
43. Wang H., Yu S. W., Koh D. W., Lew J., Coombs C., Bowers W., Federoff H. J., Poirier G. G., Dawson T. M. and Dawson V. L. (2004a) Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. J. Neurosci. 24, 10 963-10 973.
44. Wang X., Zhou Y., Kim H. P., Song R., Zarnegar R., Ryter S. W. and Choi A. M. (2004b) Hepatocyte growth factor protects against hypoxia/reoxygenation- induced apoptosis in endothelial cells. J. Biol. Chem. 279, 5237-5243.
45. Xu D., Bureau Y., McIntyre D. C., Nicholson D. W., Liston P., Zhu Y., Fong W. G., Crocker S. J., Korneluk R. G. and Robertson G. S. (1999) Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. J. Neurosci. 19, 5026-5033.
46. Ye H., Cande C., Stephanou N. C., Jiang S., Gurbuxani S., Larochette N., Daugas E., Garrido C., Kroemer G. and Wu H. (2002) DNA binding is required for the apoptogenic action of apoptosis inducing factor. Nat. Struct. Biol. 9, 680-684.
47. Yu S. W., Wang H., Poitras M. F., Coombs C., Bowers W. J., Federoff H. J., Poirier G. G., Dawson T. M. and Dawson V. L. (2002) Mediation of poly (ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297, 259-263.
48. Zarnegar R. and Michalopoulos G. K. (1995) The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J. Cell Biol. 129, 1177-1180.