메뉴 건너뛰기




Volumn 9, Issue 12, 2010, Pages 6729-6739

Mutations in the saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through 1H NMR-based metabolic footprinting

Author keywords

[No Author keywords available]

Indexed keywords

SUCCINATE DEHYDROGENASE;

EID: 78649898221     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr100880y     Document Type: Article
Times cited : (56)

References (66)
  • 4
    • 50249099816 scopus 로고    scopus 로고
    • Metabolic phenotyping in health and disease
    • Holmes, E.; Wilson, I. D.; Nicholson, J. K. Metabolic phenotyping in health and disease Cell 2008, 134 (5) 714-7
    • (2008) Cell , vol.134 , Issue.5 , pp. 714-7
    • Holmes, E.1    Wilson, I.D.2    Nicholson, J.K.3
  • 10
    • 3042823722 scopus 로고    scopus 로고
    • Metabolic profiles of cancer cells
    • Griffin, J. L.; Shockcor, J. P. Metabolic profiles of cancer cells Nat. Rev. Cancer 2004, 4 (7) 551-561
    • (2004) Nat. Rev. Cancer , vol.4 , Issue.7 , pp. 551-561
    • Griffin, J.L.1    Shockcor, J.P.2
  • 11
    • 0038699591 scopus 로고    scopus 로고
    • High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    • Allen, J.; Davey, H. M.; Broadhurst, D.; Heald, J. K.; Rowland, J. J.; Oliver, S. G.; Kell, D. B. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting Nat. Biotechnol. 2003, 21 (6) 692-6
    • (2003) Nat. Biotechnol. , vol.21 , Issue.6 , pp. 692-6
    • Allen, J.1    Davey, H.M.2    Broadhurst, D.3    Heald, J.K.4    Rowland, J.J.5    Oliver, S.G.6    Kell, D.B.7
  • 12
    • 48849084492 scopus 로고    scopus 로고
    • Metabolic footprinting in microbiology: Methods and applications in functional genomics and biotechnology
    • Mapelli, V.; Olsson, L.; Nielsen, J. Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology Trends Biotechnol. 2008, 26 (9) 490-7
    • (2008) Trends Biotechnol. , vol.26 , Issue.9 , pp. 490-7
    • Mapelli, V.1    Olsson, L.2    Nielsen, J.3
  • 13
    • 33947590364 scopus 로고    scopus 로고
    • A comparison of direct infusion MS and GC-MS for metabolic footprinting of yeast mutants
    • Mas, S.; Villas-Bôas, S. G.; Hansen, M. E.; Åkesson, M.; Nielsen, J. A comparison of direct infusion MS and GC-MS for metabolic footprinting of yeast mutants Biotechnol. Bioeng. 2007, 96 (5) 1014-22
    • (2007) Biotechnol. Bioeng. , vol.96 , Issue.5 , pp. 1014-22
    • Mas, S.1    Villas-Bôas, S.G.2    Hansen, M.E.3    Åkesson, M.4    Nielsen, J.5
  • 14
    • 0043282812 scopus 로고    scopus 로고
    • Functional genomics via metabolic footprinting: Monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry
    • Kaderbhai, N. N.; Broadhurst, D. I.; Ellis, D. I.; Goodacre, R.; Kell, D. B. Functional genomics via metabolic footprinting: Monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry Comp. Funct. Genomics 2003, 4 (4) 376-91
    • (2003) Comp. Funct. Genomics , vol.4 , Issue.4 , pp. 376-91
    • Kaderbhai, N.N.1    Broadhurst, D.I.2    Ellis, D.I.3    Goodacre, R.4    Kell, D.B.5
  • 16
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace, D. C. Mitochondrial diseases in man and mouse Science 1999, 283 (5407) 1482-8
    • (1999) Science , vol.283 , Issue.5407 , pp. 1482-8
    • Wallace, D.C.1
  • 17
    • 0004235430 scopus 로고    scopus 로고
    • Wiley-Liss: New York,; pp xiv
    • Scheffler, I. E. Mitochondria; Wiley-Liss: New York, 1999; pp xiv, 367.
    • (1999) Mitochondria , pp. 367
    • Scheffler, I.E.1
  • 18
    • 0003118424 scopus 로고    scopus 로고
    • A century of mitochondrial research: Achievements and perspectives
    • Scheffler, I. E. A century of mitochondrial research: achievements and perspectives Mitochondrion 2000, 1, 3-31
    • (2000) Mitochondrion , vol.1 , pp. 3-31
    • Scheffler, I.E.1
  • 19
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
    • Wallace, D. C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine Annu. Rev. Genet. 2005, 39 (1) 359-407
    • (2005) Annu. Rev. Genet. , vol.39 , Issue.1 , pp. 359-407
    • Wallace, D.C.1
  • 20
    • 2942562564 scopus 로고    scopus 로고
    • Mitochondrial disorders: Prevalence, myths and advances
    • Thorburn, D. R. Mitochondrial disorders: prevalence, myths and advances J. Inherit. Metab. Dis. 2004, 27 (3) 349-62
    • (2004) J. Inherit. Metab. Dis. , vol.27 , Issue.3 , pp. 349-62
    • Thorburn, D.R.1
  • 21
    • 0035349906 scopus 로고    scopus 로고
    • The genetics and pathology of oxidative phosphorylation
    • Smeitink, J.; van den Heuvel, L.; DiMauro, S. The genetics and pathology of oxidative phosphorylation Nat. Rev. Genet. 2001, 2 (5) 342-52
    • (2001) Nat. Rev. Genet. , vol.2 , Issue.5 , pp. 342-52
    • Smeitink, J.1    Van Den Heuvel, L.2    Dimauro, S.3
  • 22
    • 73249119723 scopus 로고    scopus 로고
    • Diagnostic approach to mitochondrial disorders: The need for a reliable biomarker
    • Mancuso, M.; Orsucci, D.; Coppede, F.; Nesti, C.; Choub, A.; Siciliano, G. Diagnostic approach to mitochondrial disorders: the need for a reliable biomarker Curr. Mol. Med. 2009, 9 (9) 1095-107
    • (2009) Curr. Mol. Med. , vol.9 , Issue.9 , pp. 1095-107
    • Mancuso, M.1    Orsucci, D.2    Coppede, F.3    Nesti, C.4    Choub, A.5    Siciliano, G.6
  • 23
    • 0037122946 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae mitochondrial succinate:ubiquinone oxidoreductase
    • Lemire, B. D.; Oyedotun, K. S. The Saccharomyces cerevisiae mitochondrial succinate:ubiquinone oxidoreductase Biochim. Biophys. Acta 2002, 1553 (1-2) 102-16
    • (2002) Biochim. Biophys. Acta , vol.1553 , Issue.1-2 , pp. 102-16
    • Lemire, B.D.1    Oyedotun, K.S.2
  • 25
    • 0343052744 scopus 로고    scopus 로고
    • Succinate:quinone oxidoreductases: Variations on a conserved theme
    • Hägerhäll, C. Succinate:quinone oxidoreductases: variations on a conserved theme Biochim. Biophys. Acta 1997, 1320 (2) 107-41
    • (1997) Biochim. Biophys. Acta , vol.1320 , Issue.2 , pp. 107-41
    • Hägerhäll, C.1
  • 26
    • 77956839772 scopus 로고
    • Progress in succinate:quinone oxidoreductase research
    • Ed; Elsevier Science Publishers: New York
    • Hederstedt, L.; Ohnishi, T. Progress in succinate:quinone oxidoreductase research. In Molecular Mechanisms in Bioenergetics; Ernster, L., Ed; Elsevier Science Publishers: New York, 1992; pp 163 - 97.
    • (1992) Molecular Mechanisms in Bioenergetics , pp. 163-97
    • Hederstedt, L.1    Ohnishi, T.2    Ernster, L.3
  • 27
    • 0036805853 scopus 로고    scopus 로고
    • Cytopathies involving mitochondrial complex II
    • Ackrell, B. A. Cytopathies involving mitochondrial complex II Mol. Aspects Med. 2002, 23 (5) 369-84
    • (2002) Mol. Aspects Med. , vol.23 , Issue.5 , pp. 369-84
    • Ackrell, B.A.1
  • 29
    • 0037122936 scopus 로고    scopus 로고
    • Inborn errors of complex II - Unusual human mitochondrial diseases
    • Rustin, P.; Rötig, A. Inborn errors of complex II-Unusual human mitochondrial diseases Biochim. Biophys. Acta 2002, 1553 (1-2) 117-22
    • (2002) Biochim. Biophys. Acta , vol.1553 , Issue.1-2 , pp. 117-22
    • Rustin, P.1    Rötig, A.2
  • 31
    • 0034709403 scopus 로고    scopus 로고
    • A patient with mitochondrial myopathy associated with isolated succinate dehydrogenase deficiency
    • Sugimoto, J.; Shimohira, M.; Osawa, Y.; Matsubara, M.; Yamamoto, H.; Goto, Y.; Nonaka, I. A patient with mitochondrial myopathy associated with isolated succinate dehydrogenase deficiency Brain Dev. 2000, 22 (3) 158-62
    • (2000) Brain Dev. , vol.22 , Issue.3 , pp. 158-62
    • Sugimoto, J.1    Shimohira, M.2    Osawa, Y.3    Matsubara, M.4    Yamamoto, H.5    Goto, Y.6    Nonaka, I.7
  • 32
    • 0036062729 scopus 로고    scopus 로고
    • Succinate dehydrogenase and human diseases: New insights into a well-known enzyme
    • Rustin, P.; Munnich, A.; Rötig, A. Succinate dehydrogenase and human diseases: new insights into a well-known enzyme Eur. J. Hum. Genet. 2002, 10 (5) 289-91
    • (2002) Eur. J. Hum. Genet. , vol.10 , Issue.5 , pp. 289-91
    • Rustin, P.1    Munnich, A.2    Rötig, A.3
  • 33
    • 0034803010 scopus 로고    scopus 로고
    • Phenotypic dichotomy in mitochondrial complex II genetic disorders
    • Baysal, B. E.; Rubinstein, W. S.; Taschner, P. E. Phenotypic dichotomy in mitochondrial complex II genetic disorders J. Mol. Med. 2001, 79 (9) 495-503
    • (2001) J. Mol. Med. , vol.79 , Issue.9 , pp. 495-503
    • Baysal, B.E.1    Rubinstein, W.S.2    Taschner, P.E.3
  • 34
    • 2142744836 scopus 로고    scopus 로고
    • Reduced expression and loss of heterozygosity of the SDHD gene in colorectal and gastric cancer
    • Habano, W.; Sugai, T.; Nakamura, S.; Uesugi, N.; Higuchi, T.; Terashima, M.; Horiuchi, S. Reduced expression and loss of heterozygosity of the SDHD gene in colorectal and gastric cancer Oncol. Rep. 2003, 10 (5) 1375-80
    • (2003) Oncol. Rep. , vol.10 , Issue.5 , pp. 1375-80
    • Habano, W.1    Sugai, T.2    Nakamura, S.3    Uesugi, N.4    Higuchi, T.5    Terashima, M.6    Horiuchi, S.7
  • 38
    • 0035874016 scopus 로고    scopus 로고
    • Novel mutations and the emergence of a common mutation in the SDHD gene causing familial paraganglioma
    • Milunsky, J. M.; Maher, T. A.; Michels, V. V.; Milunsky, A. Novel mutations and the emergence of a common mutation in the SDHD gene causing familial paraganglioma Am. J. Med. Genet. 2001, 100 (4) 311-4
    • (2001) Am. J. Med. Genet. , vol.100 , Issue.4 , pp. 311-4
    • Milunsky, J.M.1    Maher, T.A.2    Michels, V.V.3    Milunsky, A.4
  • 39
    • 34848866025 scopus 로고    scopus 로고
    • Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate
    • Szeto, S. S.; Reinke, S. N.; Sykes, B. D.; Lemire, B. D. Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate J. Biol. Chem. 2007, 282 (37) 27518-26
    • (2007) J. Biol. Chem. , vol.282 , Issue.37 , pp. 27518-26
    • Szeto, S.S.1    Reinke, S.N.2    Sykes, B.D.3    Lemire, B.D.4
  • 40
    • 29144484161 scopus 로고    scopus 로고
    • The SDH mutation database: An online resource for succinate dehydrogenase sequence variants involved in pheochromocytoma, paraganglioma and mitochondrial complex II deficiency
    • Bayley, J. P.; Devilee, P.; Taschner, P. E. The SDH mutation database: an online resource for succinate dehydrogenase sequence variants involved in pheochromocytoma, paraganglioma and mitochondrial complex II deficiency BMC Med. Genet. 2005, 6 (1) 39
    • (2005) BMC Med. Genet. , vol.6 , Issue.1 , pp. 39
    • Bayley, J.P.1    Devilee, P.2    Taschner, P.E.3
  • 41
    • 21244503033 scopus 로고    scopus 로고
    • Crystal structure of mitochondrial respiratory membrane protein complex II
    • Sun, F.; Huo, X.; Zhai, Y.; Wang, A.; Xu, J.; Su, D.; Bartlam, M.; Rao, Z. Crystal structure of mitochondrial respiratory membrane protein complex II Cell 2005, 121 (7) 1043-57
    • (2005) Cell , vol.121 , Issue.7 , pp. 1043-57
    • Sun, F.1    Huo, X.2    Zhai, Y.3    Wang, A.4    Xu, J.5    Su, D.6    Bartlam, M.7    Rao, Z.8
  • 42
    • 1542364465 scopus 로고    scopus 로고
    • The quaternary structure of the Saccharomyces cerevisiae succinate dehydrogenase: Homology modeling, cofactor docking, and molecular dynamics simulation studies
    • Oyedotun, K. S.; Lemire, B. D. The quaternary structure of the Saccharomyces cerevisiae succinate dehydrogenase: Homology modeling, cofactor docking, and molecular dynamics simulation studies J. Biol. Chem. 2004, 279 (10) 9424-31
    • (2004) J. Biol. Chem. , vol.279 , Issue.10 , pp. 9424-31
    • Oyedotun, K.S.1    Lemire, B.D.2
  • 43
    • 0031440279 scopus 로고    scopus 로고
    • The carboxyl terminus of the Saccharomyces cerevisiae succinate dehydrogenase membrane subunit, Sdh4p, is necessary for ubiquinone reduction and enzyme stability
    • Oyedotun, K. S.; Lemire, B. D. The carboxyl terminus of the Saccharomyces cerevisiae succinate dehydrogenase membrane subunit, Sdh4p, is necessary for ubiquinone reduction and enzyme stability J. Biol. Chem. 1997, 272 (50) 31382-8
    • (1997) J. Biol. Chem. , vol.272 , Issue.50 , pp. 31382-8
    • Oyedotun, K.S.1    Lemire, B.D.2
  • 44
    • 0033588181 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase. Identification of Sdh3p amino acid residues involved in ubiquinone binding
    • Oyedotun, K. S.; Lemire, B. D. The Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase. Identification of Sdh3p amino acid residues involved in ubiquinone binding J. Biol. Chem. 1999, 274 (34) 23956-62
    • (1999) J. Biol. Chem. , vol.274 , Issue.34 , pp. 23956-62
    • Oyedotun, K.S.1    Lemire, B.D.2
  • 45
    • 0026562884 scopus 로고
    • Improved method for high efficiency transformation of intact yeast cells
    • Gietz, D.; St Jean, A.; Woods, R. A.; Schiestl, R. H. Improved method for high efficiency transformation of intact yeast cells Nucleic Acids Res. 1992, 20 (6) 1425
    • (1992) Nucleic Acids Res. , vol.20 , Issue.6 , pp. 1425
    • Gietz, D.1    St Jean, A.2    Woods, R.A.3    Schiestl, R.H.4
  • 46
    • 0016749297 scopus 로고
    • EPR studies on the respiratory chain of wild-type Saccharomyces cerevisiae and mutants with a deficiency in succinate dehydrogenase
    • de Kok, J.; Muller, J. L. M.; Slater, E. C. EPR studies on the respiratory chain of wild-type Saccharomyces cerevisiae and mutants with a deficiency in succinate dehydrogenase Biochim. Biophys. Acta 1975, 387, 441-50
    • (1975) Biochim. Biophys. Acta , vol.387 , pp. 441-50
    • De Kok, J.1    Muller, J.L.M.2    Slater, E.C.3
  • 47
    • 77953028990 scopus 로고    scopus 로고
    • Caenorhabditis elegans diet significantly affects metabolic profile, mitochondrial DNA levels, lifespan and brood size
    • Reinke, S. N.; Hu, X.; Sykes, B. D.; Lemire, B. D. Caenorhabditis elegans diet significantly affects metabolic profile, mitochondrial DNA levels, lifespan and brood size Mol. Genet. Metab. 2010, 100 (3) 274-82
    • (2010) Mol. Genet. Metab. , vol.100 , Issue.3 , pp. 274-82
    • Reinke, S.N.1    Hu, X.2    Sykes, B.D.3    Lemire, B.D.4
  • 51
    • 0035907323 scopus 로고    scopus 로고
    • The quinone-binding sites of the Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase
    • Oyedotun, K. S.; Lemire, B. D. The quinone-binding sites of the Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase J. Biol. Chem. 2001, 276, 16936-43
    • (2001) J. Biol. Chem. , vol.276 , pp. 16936-43
    • Oyedotun, K.S.1    Lemire, B.D.2
  • 52
    • 1542274585 scopus 로고    scopus 로고
    • 562 of the Saccharomyces cerevisiae succinate dehydrogenase
    • 562 of the Saccharomyces cerevisiae succinate dehydrogenase J. Biol. Chem. 2004, 279 (10) 9432-9
    • (2004) J. Biol. Chem. , vol.279 , Issue.10 , pp. 9432-9
    • Oyedotun, K.S.1    Yau, P.F.2    Lemire, B.D.3
  • 53
    • 13244295382 scopus 로고    scopus 로고
    • Pseudomonas-Saccharomyces interactions: Influence of fungal metabolism on bacterial physiology and survival
    • Romano, J. D.; Kolter, R. Pseudomonas-Saccharomyces interactions: influence of fungal metabolism on bacterial physiology and survival J. Bacteriol. 2005, 187 (3) 940-8
    • (2005) J. Bacteriol. , vol.187 , Issue.3 , pp. 940-8
    • Romano, J.D.1    Kolter, R.2
  • 55
    • 0025738416 scopus 로고
    • Isolation and characterization of carnitine acetyltransferase from S. cerevisiae
    • Kispal, G.; Cseko, J.; Alkonyi, I.; Sandor, A. Isolation and characterization of carnitine acetyltransferase from S. cerevisiae Biochim. Biophys. Acta 1991, 1085 (2) 217-22
    • (1991) Biochim. Biophys. Acta , vol.1085 , Issue.2 , pp. 217-22
    • Kispal, G.1    Cseko, J.2    Alkonyi, I.3    Sandor, A.4
  • 56
    • 0027390693 scopus 로고
    • Cloning and sequencing of a cDNA encoding Saccharomyces cerevisiae carnitine acetyltransferase. Use of the cDNA in gene disruption studies
    • Kispal, G.; Sumegi, B.; Dietmeier, K.; Bock, I.; Gajdos, G.; Tomcsanyi, T.; Sandor, A. Cloning and sequencing of a cDNA encoding Saccharomyces cerevisiae carnitine acetyltransferase. Use of the cDNA in gene disruption studies J. Biol. Chem. 1993, 268 (3) 1824-9
    • (1993) J. Biol. Chem. , vol.268 , Issue.3 , pp. 1824-9
    • Kispal, G.1    Sumegi, B.2    Dietmeier, K.3    Bock, I.4    Gajdos, G.5    Tomcsanyi, T.6    Sandor, A.7
  • 57
    • 0028218011 scopus 로고
    • Energetic aspects of glucose metabolism in a pyruvate-dehydrogenase- negative mutant of Saccharomyces cerevisiae
    • Pronk, J. T.; Wenzel, T. J.; Luttik, M. A.; Klaassen, C. C.; Scheffers, W. A.; Steensma, H. Y.; van Dijken, J. P. Energetic aspects of glucose metabolism in a pyruvate-dehydrogenase-negative mutant of Saccharomyces cerevisiae Microbiology 1994, 140 (Pt 3) 601-10
    • (1994) Microbiology , vol.140 , Issue.PART 3 , pp. 601-10
    • Pronk, J.T.1    Wenzel, T.J.2    Luttik, M.A.3    Klaassen, C.C.4    Scheffers, W.A.5    Steensma, H.Y.6    Van Dijken, J.P.7
  • 58
    • 0038269064 scopus 로고    scopus 로고
    • Functional characterization and localization of acetyl-CoA hydrolase, Ach1p, in Saccharomyces cerevisiae
    • Buu, L. M.; Chen, Y. C.; Lee, F. J. Functional characterization and localization of acetyl-CoA hydrolase, Ach1p, in Saccharomyces cerevisiae J. Biol. Chem. 2003, 278 (19) 17203-9
    • (2003) J. Biol. Chem. , vol.278 , Issue.19 , pp. 17203-9
    • Buu, L.M.1    Chen, Y.C.2    Lee, F.J.3
  • 63
    • 1342290477 scopus 로고    scopus 로고
    • Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae
    • Sandra, P.; Frederic, D.; Sonia, B.; Claude, J.; Margarida, C. Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae Yeast 2004, 21 (3) 201-10
    • (2004) Yeast , vol.21 , Issue.3 , pp. 201-10
    • Sandra, P.1    Frederic, D.2    Sonia, B.3    Claude, J.4    Margarida, C.5
  • 66
    • 42349106782 scopus 로고    scopus 로고
    • The Ehrlich pathway for fusel alcohol production: A century of research on Saccharomyces cerevisiae metabolism
    • Hazelwood, L. A.; Daran, J. M.; van Maris, A. J.; Pronk, J. T.; Dickinson, J. R. The Ehrlich pathway for fusel alcohol production: a century of research on Saccharomyces cerevisiae metabolism Appl. Environ. Microbiol. 2008, 74 (8) 2259-66
    • (2008) Appl. Environ. Microbiol. , vol.74 , Issue.8 , pp. 2259-66
    • Hazelwood, L.A.1    Daran, J.M.2    Van Maris, A.J.3    Pronk, J.T.4    Dickinson, J.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.