메뉴 건너뛰기




Volumn 10, Issue 7, 2010, Pages 543-555

Emerging therapeutic targets and agents for glioblastoma migrating cells

Author keywords

AJAP; Chemotherapy; Glioblastoma; Tumor cell migration

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; 4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 6 [4 (4 ETHYL 1 PIPERAZINYLMETHYL)PHENYL] 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; AP 12009; AZD 4547; CYTOKINE; DASATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FIBROBLAST GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; GEFITINIB; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GROWTH FACTOR; IMATINIB; IMMUNOGLOBULIN; INTEGRIN; LAPATINIB; LLL 12; N [4 (3 CHLORO 4 FLUOROANILINO) 7 (TETRAHYDRO 3 FURYLOXY) 6 QUINAZOLINYL] 4 DIMETHYLAMINO 2 BUTENAMIDE; PAZOPANIB; PERIFOSINE; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; SORAFENIB; TANDUTINIB; TLN 4601; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; UROKINASE; VATALANIB; WP 1034; WX 671; XL 184; XL 765;

EID: 78649882830     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152010793498618     Document Type: Article
Times cited : (12)

References (136)
  • 1
    • 0001826365 scopus 로고
    • The forms of growth in gliomas and their practicalsignificance
    • Scherer, H. J. The forms of growth in gliomas and their practicalsignificance. Brain 1940, 63, 1-35.
    • (1940) Brain , vol.63 , pp. 1-35
    • Scherer, H.J.1
  • 2
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signalling bycadherins and Ig-CAMs in cancer
    • Cavallaro, U.; Christofori, G. Cell adhesion and signalling bycadherins and Ig-CAMs in cancer. Nat. Rev. Cancer, 2004, 4(2), 118-132.
    • (2004) Nat. Rev. Cancer , vol.4 , Issue.2 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2
  • 3
    • 0032525219 scopus 로고    scopus 로고
    • Expression of the neural cell adhesionmolecule in astrocytic tumors
    • Sasaki, H.; Yoshida, K.; Ikeda, E.; Asou, H.; Inaba, M.; Otani, M.; Kawase, T. Expression of the neural cell adhesionmolecule in astrocytic tumors. Cancer, 1998, 82(10), 1921-1931.
    • (1998) Cancer , vol.82 , Issue.10 , pp. 1921-1931
    • Sasaki, H.1    Yoshida, K.2    Ikeda, E.3    Asou, H.4    Inaba, M.5    Otani, M.6    Kawase, T.7
  • 5
    • 67649619278 scopus 로고    scopus 로고
    • AMPA receptors promoteperivascular glioma invasion via β1 integrin-dependent adhesion tothe extracellular matrix
    • Piao, Y.; Lu, L.; de Groot, J. AMPA receptors promoteperivascular glioma invasion via β1 integrin-dependent adhesion tothe extracellular matrix. Neuro-Oncology, 2009, 11(3), 260-273.
    • (2009) Neuro-Oncology , vol.11 , Issue.3 , pp. 260-273
    • Piao, Y.1    Lu, L.2    de Groot, J.3
  • 6
    • 36049005089 scopus 로고    scopus 로고
    • Chemokine and cytokine processing bymatrix metalloproteinases and its effect on leukocyte migration and inflammation
    • Van Lint, P.; Libert, C. Chemokine and cytokine processing bymatrix metalloproteinases and its effect on leukocyte migration and inflammation. J. Leukoc. Biol., 2007, 82(6), 1375-1381.
    • (2007) J. Leukoc. Biol. , vol.82 , Issue.6 , pp. 1375-1381
    • Van Lint, P.1    Libert, C.2
  • 9
    • 0027530832 scopus 로고
    • Effectsof EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratoryand invasive capacities of human brain-tumour biopsies in vitro
    • Engebraaten, O.; Bjerkvig, R.; Pedersen, P.; Laerum, O. Effectsof EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratoryand invasive capacities of human brain-tumour biopsies in vitro.Int. J. Cancer, 1993, 53(2), 209-214.
    • (1993) Int. J. Cancer , vol.53 , Issue.2 , pp. 209-214
    • Engebraaten, O.1    Bjerkvig, R.2    Pedersen, P.3    Laerum, O.4
  • 10
    • 0028351179 scopus 로고
    • Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-a, bFGF, IL-2] on glioma spheriod growth, migration and invasion
    • Pedersen, P.-H.; Ness, G.; Engebraaten, O.; Bjerkvig, R.; Lillehaug, J.; Laerum, O.Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-a, bFGF, IL-2] on glioma spheriod growth, migration and invasion. Int. J. Cancer, 1994, 56(2), 255-261.
    • (1994) Int. J. Cancer , vol.56 , Issue.2 , pp. 255-261
    • Pedersen, P.-H.1    Ness, G.2    Engebraaten, O.3    Bjerkvig, R.4    Lillehaug, J.5    Laerum, O.6
  • 11
    • 0028852725 scopus 로고
    • Growth factors and gangliosidesstimulate laminin production by human glioma cells in vitro
    • Koochekpour, S.; Merzak, A.; Pilkington, G. J. Growth factors and gangliosidesstimulate laminin production by human glioma cells in vitro.Neurosci. Lett., 1995, 186(1), 53-56.
    • (1995) Neurosci. Lett. , vol.186 , Issue.1 , pp. 53-56
    • Koochekpour, S.1    Merzak, A.2    Pilkington, G.J.3
  • 12
    • 0034789517 scopus 로고    scopus 로고
    • Receptor tyrosine kinasesignalling as a target for cancer intervention strategies
    • Zwick, E.; Bange, J.; Ullrich, A. Receptor tyrosine kinasesignalling as a target for cancer intervention strategies. Endocr.Relat. Cancer, 2001, 8(3), 161-173.
    • (2001) Endocr.Relat. Cancer , vol.8 , Issue.3 , pp. 161-173
    • Zwick, E.1    Bange, J.2    Ullrich, A.3
  • 13
    • 0034693799 scopus 로고    scopus 로고
    • The protein tyrosine kinasefamily of the human genome
    • Robinson, D. R.; Wu, Y.-M.; Lin, S.-F. The protein tyrosine kinasefamily of the human genome. Oncogene, 2000, 19(49), 5548-5557.
    • (2000) Oncogene , vol.19 , Issue.49 , pp. 5548-5557
    • Robinson, D.R.1    Wu, Y.-M.2    Lin, S.-F.3
  • 14
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger, J. Cell signaling by receptor tyrosine kinases. Cell, 2000, 103(2), 211-225.
    • (2000) Cell , vol.103 , Issue.2 , pp. 211-225
    • Schlessinger, J.1
  • 15
    • 0035941258 scopus 로고    scopus 로고
    • Identification of a heregulin binding site in HER3 extracellulardomain
    • Singer, E.; Landgraf, R.; Horan, T.; Slamon, D.; Eisenberg, D.Identification of a heregulin binding site in HER3 extracellulardomain. J. Biol. Chem., 2001, 276(47), 44266-44274.
    • (2001) J. Biol. Chem. , vol.276 , Issue.47 , pp. 44266-44274
    • Singer, E.1    Landgraf, R.2    Horan, T.3    Slamon, D.4    Eisenberg, D.5
  • 17
    • 0033980837 scopus 로고    scopus 로고
    • Interaction of the PA2G4(EBP1) protein with ErbB-3 and regulation of this binding byheregulin
    • Yoo, J.-Y.; Wang, X.W.; Rishi, A. K.; Lessor, T.; Xia, X.-M.; Gustafson, T. A.; Hamburger, A. W. Interaction of the PA2G4(EBP1) protein with ErbB-3 and regulation of this binding byheregulin. Br. J. Cancer, 2000, 82(3), 683-690.
    • (2000) Br. J. Cancer , vol.82 , Issue.3 , pp. 683-690
    • Yoo, J.-Y.1    Wang, X.W.2    Rishi, A.K.3    Lessor, T.4    Xia, X.-M.5    Gustafson, T.A.6    Hamburger, A.W.7
  • 18
    • 0037810425 scopus 로고    scopus 로고
    • Identificationof novel ErbB3-interacting factors using the split-ubiquitinmembrane yeast two-hybrid system
    • Thaminy, S.; Auerbach, D.; Arnoldo, A.; Stagljar, I. Identificationof novel ErbB3-interacting factors using the split-ubiquitinmembrane yeast two-hybrid system. Genome Res., 2003, 13(7), 1744-1753.
    • (2003) Genome Res. , vol.13 , Issue.7 , pp. 1744-1753
    • Thaminy, S.1    Auerbach, D.2    Arnoldo, A.3    Stagljar, I.4
  • 19
    • 8444243682 scopus 로고    scopus 로고
    • The ERBB4/HER4receptor tyrosine kinase regulates gene expression by functioningas a STAT5A nuclear chaperone
    • Williams, C. C.; Allison, J. G.; Vidal, G. A.; Burow, M. E.; Beckman, B. S.; Marrero, L.; Jones, F. E. The ERBB4/HER4receptor tyrosine kinase regulates gene expression by functioningas a STAT5A nuclear chaperone. J. Cell Biol., 2004, 167(3), 469-478.
    • (2004) J. Cell Biol. , vol.167 , Issue.3 , pp. 469-478
    • Williams, C.C.1    Allison, J.G.2    Vidal, G.A.3    Burow, M.E.4    Beckman, B.S.5    Marrero, L.6    Jones, F.E.7
  • 20
    • 33746905531 scopus 로고    scopus 로고
    • Phosphotyrosineinteractome of the ErbB-receptor kinase family
    • Schulze, W. X.; Deng, L.; Mann, M. Phosphotyrosineinteractome of the ErbB-receptor kinase family. Mol. Syst. Biol., 2005, 1, 2005.0008.
    • (2005) Mol. Syst. Biol. , vol.1 , pp. 20050008
    • Schulze, W.X.1    Deng, L.2    Mann, M.3
  • 21
    • 0034724391 scopus 로고    scopus 로고
    • The neuregulinreceptor ErbB-4 interacts with PDZ-containing proteins at neuronalsynapses
    • Garcia, R. A. G.; Vasudevan, K.; Buonanno, A. The neuregulinreceptor ErbB-4 interacts with PDZ-containing proteins at neuronalsynapses. Proc.Natl. Acad. Sci. USA, 2000, 97(7), 3596-3601.
    • (2000) Proc.Natl. Acad. Sci. USA , vol.97 , Issue.7 , pp. 3596-3601
    • Garcia, R.A.G.1    Vasudevan, K.2    Buonanno, A.3
  • 24
    • 33750209646 scopus 로고    scopus 로고
    • EGFRvIII undergoes activation-dependentdownregulation mediated by the Cbl proteins
    • Davies, G. C.; Ryan, P. E.; Rahman, L.; Zajac-Kaye, M.; Lipkowitz, S. EGFRvIII undergoes activation-dependentdownregulation mediated by the Cbl proteins. Oncogene, 2006, 25(49), 6497-6509.
    • (2006) Oncogene , vol.25 , Issue.49 , pp. 6497-6509
    • Davies, G.C.1    Ryan, P.E.2    Rahman, L.3    Zajac-Kaye, M.4    Lipkowitz, S.5
  • 25
    • 70350215773 scopus 로고    scopus 로고
    • Epidermal growth factor receptor variantIII-induced glioma invasion is mediated through myristoylatedalanine-rich protein kinase C substrate overexpression
    • Micallef, J.; Taccone, M.; Mukherjee, J.; Croul, S.; Busby, J.; Moran, M. F.; Guha, A. Epidermal growth factor receptor variantIII-induced glioma invasion is mediated through myristoylatedalanine-rich protein kinase C substrate overexpression. CancerRes., 2009, 69(19), 7548-7556.
    • (2009) CancerRes. , vol.69 , Issue.19 , pp. 7548-7556
    • Micallef, J.1    Taccone, M.2    Mukherjee, J.3    Croul, S.4    Busby, J.5    Moran, M.F.6    Guha, A.7
  • 26
    • 73949083511 scopus 로고    scopus 로고
    • Oncogenic EGFR signalingnetworks in glioma
    • Huang, P. H.; Xu, A. M.; White, F. M. Oncogenic EGFR signalingnetworks in glioma. Sci. Signal., 2009, 2(87), re6.
    • (2009) Sci. Signal. , vol.2 , Issue.87
    • Huang, P.H.1    Xu, A.M.2    White, F.M.3
  • 27
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomiccharacterization defines human glioblastoma genes and corepathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive genomiccharacterization defines human glioblastoma genes and corepathways. Nature, 2008, 455(7216), 1061-8.
    • (2008) Nature , vol.455 , Issue.7216 , pp. 1061-1068
  • 28
    • 85036702613 scopus 로고    scopus 로고
    • From Ras to PI3K
    • Gough, N. R. From Ras to PI3K. Sci. Signal., 2006, 2006(362), tw397.
    • (2006) Sci. Signal. , vol.2006 , Issue.362
    • Gough, N.R.1
  • 29
    • 64349116712 scopus 로고    scopus 로고
    • Interactions between PTEN and receptor tyrosinekinase pathways and their implications for glioma therapy
    • Abounader, R. Interactions between PTEN and receptor tyrosinekinase pathways and their implications for glioma therapy. ExpertRev. Anticancer Ther., 2009, 9(2), 235-245.
    • (2009) ExpertRev. Anticancer Ther. , vol.9 , Issue.2 , pp. 235-245
    • Abounader, R.1
  • 31
    • 4344602002 scopus 로고    scopus 로고
    • The biology and clinical relevance of thePTEN tumor suppressor pathway
    • Sansal, I.; Sellers, W. R. The biology and clinical relevance of thePTEN tumor suppressor pathway. J. Clin. Oncol., 2004, 22(14), 2954-2963.
    • (2004) J. Clin. Oncol. , vol.22 , Issue.14 , pp. 2954-2963
    • Sansal, I.1    Sellers, W.R.2
  • 32
    • 0035884505 scopus 로고    scopus 로고
    • Akt pathway activation converts anaplasticastrocytoma to glioblastoma multiforme in a human astrocytemodel of glioma
    • Sonoda, Y.; Ozawa, T.; Aldape, K. D.; Deen, D. F.; Berger, M. S.; Pieper, R. O. Akt pathway activation converts anaplasticastrocytoma to glioblastoma multiforme in a human astrocytemodel of glioma. Cancer Res., 2001, 61(18), 6674-6678.
    • (2001) Cancer Res. , vol.61 , Issue.18 , pp. 6674-6678
    • Sonoda, Y.1    Ozawa, T.2    Aldape, K.D.3    Deen, D.F.4    Berger, M.S.5    Pieper, R.O.6
  • 33
    • 0041378169 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate stimulates motility and invasiveness of humanglioblastoma multiforme cells
    • Van Brocklyn, J. R.; Young, N.; Roof, R. Sphingosine-1-phosphate stimulates motility and invasiveness of humanglioblastoma multiforme cells. Cancer Lett., 2003, 199(1), 53-60.
    • (2003) Cancer Lett. , vol.199 , Issue.1 , pp. 53-60
    • Van Brocklyn, J.R.1    Young, N.2    Roof, R.3
  • 35
    • 58749094798 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate regulates glioblastomacell invasiveness through the urokinase plasminogen activatorsystem and CCN1/Cyr61
    • Young, N.; Pearl, D. K.; Van Brocklyn, J. R. Sphingosine-1-phosphate regulates glioblastomacell invasiveness through the urokinase plasminogen activatorsystem and CCN1/Cyr61. Mol. Cancer Res., 2009, 7(1), 23-32.
    • (2009) Mol. Cancer Res. , vol.7 , Issue.1 , pp. 23-32
    • Young, N.1    Pearl, D.K.2    Van Brocklyn, J.R.3
  • 36
    • 34247174943 scopus 로고    scopus 로고
    • Roles of sphingosine-1-phosphate(S1P) receptors in malignant behavior of glioma cells. Differentialeffects of S1P2 on cell migration and invasiveness
    • Young, N.; Van Brocklyn, J. R. Roles of sphingosine-1-phosphate(S1P) receptors in malignant behavior of glioma cells. Differentialeffects of S1P2 on cell migration and invasiveness. Expert. CellRes., 2007, 313 (8), 1615-1627.
    • (2007) Expert. CellRes. , vol.313 , Issue.8 , pp. 1615-1627
    • Young, N.1    Van Brocklyn, J.R.2
  • 37
    • 77953136445 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mediatedregulation of urokinase plasminogen activator expression and glioblastoma invasion via C-SRC/MAPK/AP-1 signaling pathways
    • Amos, S.; Redpath, G. T.; diPierro, C. G.; Carpenter, J. E.; Hussaini, I. M. Epidermal growth factor receptor-mediatedregulation of urokinase plasminogen activator expression and glioblastoma invasion via C-SRC/MAPK/AP-1 signaling pathways.J. Neuropathol. Expert Neurol., 2010, 69(6), 582-592.
    • (2010) J. Neuropathol. Expert Neurol. , vol.69 , Issue.6 , pp. 582-592
    • Amos, S.1    Redpath, G.T.2    DiPierro, C.G.3    Carpenter, J.E.4    Hussaini, I.M.5
  • 39
    • 72249111499 scopus 로고    scopus 로고
    • Loss of collapsin response mediatorprotein1, as detected by iTRAQ analysis, promotes invasion of human gliomas expressing mutant EGFRvIII
    • Mukherjee, J.; DeSouza, L. V.; Micallef, J.; Karim, Z.; Croul, S.; Siu, K. W. M.; Guha, A. Loss of collapsin response mediatorprotein1, as detected by iTRAQ analysis, promotes invasion of human gliomas expressing mutant EGFRvIII. Cancer Res., 2009, 69(22), 8545-8554.
    • (2009) Cancer Res. , vol.69 , Issue.22 , pp. 8545-8554
    • Mukherjee, J.1    DeSouza, L.V.2    Micallef, J.3    Karim, Z.4    Croul, S.5    Siu, K.W.M.6    Guha, A.7
  • 40
    • 67349137902 scopus 로고    scopus 로고
    • The EGFRvIII variant inglioblastoma multiforme
    • Gan, H. K.; Kaye, A. H.; Luwor, R. B. The EGFRvIII variant inglioblastoma multiforme. J. Clin. Neurosci., 2009, 16(6), 748-754.
    • (2009) J. Clin. Neurosci. , vol.16 , Issue.6 , pp. 748-754
    • Gan, H.K.1    Kaye, A.H.2    Luwor, R.B.3
  • 41
    • 77249096843 scopus 로고    scopus 로고
    • Platelet-derived growth factor BB mediates thetropism of human mesenchymal stem cells for malignant gliomas
    • Hata, N.; Shinojima, N.; Gumin, J.; Yong, R.; Marini, F.; Andreeff, M.; Lang, F. F. Platelet-derived growth factor BB mediates thetropism of human mesenchymal stem cells for malignant gliomas.Neurosurgery, 2010, 66(1), 144-157.
    • (2010) Neurosurgery , vol.66 , Issue.1 , pp. 144-157
    • Hata, N.1    Shinojima, N.2    Gumin, J.3    Yong, R.4    Marini, F.5    Andreeff, M.6    Lang, F.F.7
  • 42
    • 0030771026 scopus 로고    scopus 로고
    • Signal transduction pathwaysand their relevance in human astrocytomas
    • Feldkamp, M. M.; Lau, N.; Guha, A. Signal transduction pathwaysand their relevance in human astrocytomas. J. Neuro-Oncology, 1997, 35(3), 223-248.
    • (1997) J. Neuro-Oncology , vol.35 , Issue.3 , pp. 223-248
    • Feldkamp, M.M.1    Lau, N.2    Guha, A.3
  • 44
    • 36048994736 scopus 로고    scopus 로고
    • Autocrine factorsthat sustain glioma invasion and paracrine biology in the brainmicroenvironment
    • Hoelzinger, D. B.; Demuth, T.; Berens, M. E. Autocrine factorsthat sustain glioma invasion and paracrine biology in the brainmicroenvironment. J. Nat. Cancer Inst., 2007, 99(21), 1583-1593.
    • (2007) J. Nat. Cancer Inst. , vol.99 , Issue.21 , pp. 1583-1593
    • Hoelzinger, D.B.1    Demuth, T.2    Berens, M.E.3
  • 45
    • 54049153684 scopus 로고    scopus 로고
    • EphA4 promotes cell proliferation and migration through anovel EphA4-FGFR1 signaling pathway in the human glioma U251cell line
    • Fukai, J.; Yokote, H.; Yamanaka, R.; Arao, T.; Nishio, K.; Itakura, T. EphA4 promotes cell proliferation and migration through anovel EphA4-FGFR1 signaling pathway in the human glioma U251cell line. Mol. Cancer Ther., 2008, 7(9), 2768-2778.
    • (2008) Mol. Cancer Ther. , vol.7 , Issue.9 , pp. 2768-2778
    • Fukai, J.1    Yokote, H.2    Yamanaka, R.3    Arao, T.4    Nishio, K.5    Itakura, T.6
  • 46
    • 0034693857 scopus 로고    scopus 로고
    • Eph receptors and ephrinligands: Embryogenesis to tumorigenesis
    • Dodelet, V. C.; Pasquale, E. B. Eph receptors and ephrinligands: embryogenesis to tumorigenesis. Oncogene, 2000, 19(49), 5614-5619.
    • (2000) Oncogene , vol.19 , Issue.49 , pp. 5614-5619
    • Dodelet, V.C.1    Pasquale, E.B.2
  • 47
    • 23044435769 scopus 로고    scopus 로고
    • Ephmodulatedcell morphology, adhesion and motility incarcinogenesis
    • Wimmer-Kleikamp, S. H.; Lackmann, M. Ephmodulatedcell morphology, adhesion and motility incarcinogenesis. IUBMB Life, 2005, 57(6), 421-431.
    • (2005) IUBMB Life , vol.57 , Issue.6 , pp. 421-431
    • Wimmer-Kleikamp, S.H.1    Lackmann, M.2
  • 48
    • 57749121465 scopus 로고    scopus 로고
    • The EphA2 receptor and ephrinA1ligand in solid tumors: Function and therapeutic targeting
    • Wykosky, J.; Debinski, W. The EphA2 receptor and ephrinA1ligand in solid tumors: function and therapeutic targeting. Mol.Cancer Res., 2008, 6(12), 1795-1806.
    • (2008) Mol.Cancer Res. , vol.6 , Issue.12 , pp. 1795-1806
    • Wykosky, J.1    Debinski, W.2
  • 49
    • 33748997415 scopus 로고    scopus 로고
    • E.Ephrin-B3 ligand promotes glioma invasion through activation of Rac1
    • Nakada, M.; Drake, K. L.; Nakada, S.; Niska, J. A.; Berens, M. E.Ephrin-B3 ligand promotes glioma invasion through activation of Rac1. Cancer Res., 2006, 66(17), 8492-500.
    • (2006) Cancer Res. , vol.66 , Issue.17 , pp. 8492-8500
    • Nakada, M.1    Drake, K.L.2    Nakada, S.3    Niska, J.A.4    Berens, M.5
  • 50
    • 2342577589 scopus 로고    scopus 로고
    • The phosphorylation of EphB2 receptorregulates migration and invasion of human glioma cells
    • Nakada, M.; Niska, J. A.; Miyamori, H.; McDonough, W. S.; Wu, J.; Sato, H.; Berens, M. E. The phosphorylation of EphB2 receptorregulates migration and invasion of human glioma cells. CancerRes., 2004, 64(9), 3179-85.
    • (2004) CancerRes. , vol.64 , Issue.9 , pp. 3179-3185
    • Nakada, M.1    Niska, J.A.2    Miyamori, H.3    McDonough, W.S.4    Wu, J.5    Sato, H.6    Berens, M.E.7
  • 55
    • 77954383548 scopus 로고    scopus 로고
    • HGF upregulates CXCR4expression in gliomas via NF-κB: Implications for glioma cellmigration
    • Esencay, M.; Newcomb, E.; Zagzag, D. HGF upregulates CXCR4expression in gliomas via NF-κB: implications for glioma cellmigration. J. Neuro-Oncol., 2010, 99(1), 33-40.
    • (2010) J. Neuro-Oncol. , vol.99 , Issue.1 , pp. 33-40
    • Esencay, M.1    Newcomb, E.2    Zagzag, D.3
  • 56
    • 0028921573 scopus 로고
    • Jaks and Stats in signaling by thecytokine receptor superfamily
    • Ihle, J. N.; Kerr, I. M. Jaks and Stats in signaling by thecytokine receptor superfamily. Trends Genet., 1995, 11(2), 69-74.
    • (1995) Trends Genet. , vol.11 , Issue.2 , pp. 69-74
    • Ihle, J.N.1    Kerr, I.M.2
  • 57
    • 0034981517 scopus 로고    scopus 로고
    • STAT proteins: Signal tranducers and activators of transcription
    • Bromberg, J.; Chen, X. STAT proteins: signal tranducers and activators of transcription. Methods Enzymol., 2001, 333, 138-151.
    • (2001) Methods Enzymol. , vol.333 , pp. 138-151
    • Bromberg, J.1    Chen, X.2
  • 58
    • 44949176222 scopus 로고    scopus 로고
    • N.; Bonni, A.Deregulation of a STAT3-interleukin 8 signaling pathwaypromotes human glioblastoma cell proliferation and invasiveness
    • de la Iglesia, N.; Konopka, G.; Lim, K.-L.; Nutt, C. L.; Bromberg, J. F.; Frank, D. A.; Mischel, P. S.; Louis, D. N.; Bonni, A.Deregulation of a STAT3-interleukin 8 signaling pathwaypromotes human glioblastoma cell proliferation and invasiveness.J. Neurosci., 2008, 28(23), 5870-5878.
    • (2008) J. Neurosci. , vol.28 , Issue.23 , pp. 5870-5878
    • de la Iglesia, N.1    Konopka, G.2    Lim, K.-L.3    Nutt, C.L.4    Bromberg, J.F.5    Frank, D.A.6    Mischel, P.S.7    Louis, D.8
  • 59
    • 73949111590 scopus 로고    scopus 로고
    • A novel small molecule, LLL12, inhibits STAT3phosphorylation and activities and exhibits potent growthsuppressiveactivity in human cancer cells
    • Lin, L.; Hutzen, B.; Li, P.-K.; Ball, S.; Zuo, M.; DeAngelis, S.; Foust, E.; Sobo, M.; Friedman, L.; Bhasin, D.; Cen, L.; Li, C.; Lin, J. A novel small molecule, LLL12, inhibits STAT3phosphorylation and activities and exhibits potent growthsuppressiveactivity in human cancer cells. Neoplasia, 2010, 12(1), 39-50.
    • (2010) Neoplasia , vol.12 , Issue.1 , pp. 39-50
    • Lin, L.1    Hutzen, B.2    Li, P.-K.3    Ball, S.4    Zuo, M.5    DeAngelis, S.6    Foust, E.7    Sobo, M.8    Friedman, L.9    Bhasin, D.10    Cen, L.11    Li, C.12    Lin, J.13
  • 60
    • 33747879766 scopus 로고    scopus 로고
    • Glial cell-derived neurotrophic factor (GDNF)promotes low-grade Hs683 glioma cell migration through JNK, ERK-1/2 and p38 MAPK signaling pathways
    • Song, H.; Moon, A. Glial cell-derived neurotrophic factor (GDNF)promotes low-grade Hs683 glioma cell migration through JNK, ERK-1/2 and p38 MAPK signaling pathways. Neurosci. Res., 2006, 56(1), 29-38.
    • (2006) Neurosci. Res. , vol.56 , Issue.1 , pp. 29-38
    • Song, H.1    Moon, A.2
  • 61
    • 0029610610 scopus 로고
    • The failure of current immunotherapy formalignant glioma. Tumor-derived TGF-beta, T-cell apoptosis, and the immune privilege of the brain
    • Weller, M.; Fontana, A. The failure of current immunotherapy formalignant glioma. Tumor-derived TGF-beta, T-cell apoptosis, and the immune privilege of the brain. Brain Res. Rev., 1995, 21(2), 128-151.
    • (1995) Brain Res. Rev. , vol.21 , Issue.2 , pp. 128-151
    • Weller, M.1    Fontana, A.2
  • 64
    • 0028146508 scopus 로고
    • J.Control of human glioma cell growth, migration and invasion invitro by transforming growth factor beta 1
    • Merzak, A.; McCrea, S.; Koocheckpour, S.; Pilkington, G. J.Control of human glioma cell growth, migration and invasion invitro by transforming growth factor beta 1. Br. J. Cancer, 1994, 70(2), 199-203.
    • (1994) Br. J. Cancer , vol.70 , Issue.2 , pp. 199-203
    • Merzak, A.1    McCrea, S.2    Koocheckpour, S.3    Pilkington, G.4
  • 65
    • 0029151472 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas
    • Nakano, A.; Tani, E.; Miyazaki, K.; Yamamoto, Y.; Furuyama, J.-i. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas. J.Neurosurg., 2009, 83(2), 298-307.
    • (2009) J.Neurosurg. , vol.83 , Issue.2 , pp. 298-307
    • Nakano, A.1    Tani, E.2    Miyazaki, K.3    Yamamoto, Y.4    Furuyama, J.-I.5
  • 66
    • 77953497753 scopus 로고    scopus 로고
    • A role for fibrillar collagen deposition and the collagen internalization receptor Endo180 in glioma invasion
    • Huijbers, I. J.; Iravani, M.; Popov, S.; Robertson, D.; Al-Sarraj, S.; Jones, C.; Isacke, C. M. A role for fibrillar collagen deposition and the collagen internalization receptor Endo180 in glioma invasion.PLoS ONE, 2010, 5(3), e9808.
    • (2010) PLoS ONE , vol.5 , Issue.3
    • Huijbers, I.J.1    Iravani, M.2    Popov, S.3    Robertson, D.4    Al-Sarraj, S.5    Jones, C.6    Isacke, C.M.7
  • 67
    • 78650290339 scopus 로고    scopus 로고
    • CX3CR1/CX3CL1 axis negatively controls gliomacell invasion and is modulated by transforming growth factorbeta1
    • Sciumè, G.; Soriani, A.; Piccoli, M.; Frati, L.; Santoni, A.; Bernardini, G. CX3CR1/CX3CL1 axis negatively controls gliomacell invasion and is modulated by transforming growth factorbeta1.Neuro-Oncology, 2010, 12(7), 701-710.
    • (2010) Neuro-Oncology , vol.12 , Issue.7 , pp. 701-710
    • Sciumè, G.1    Soriani, A.2    Piccoli, M.3    Frati, L.4    Santoni, A.5    Bernardini, G.6
  • 68
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes, R. O. Integrins: bidirectional, allosteric signaling machines.Cell, 2002, 110(6), 673-687.
    • (2002) Cell , vol.110 , Issue.6 , pp. 673-687
    • Hynes, R.O.1
  • 69
    • 0028940958 scopus 로고
    • Cerebral microenvironment influences expressionof the vitronectin gene in astrocytic tumors
    • Gladson, C. L.; Wilcox, J. N.; Sanders, L.; Gillespie, G. Y.; Cheresh, D. A. Cerebral microenvironment influences expressionof the vitronectin gene in astrocytic tumors. J. Cell Sci., 1995, 108(3), 947-956.
    • (1995) J. Cell Sci. , vol.108 , Issue.3 , pp. 947-956
    • Gladson, C.L.1    Wilcox, J.N.2    Sanders, L.3    Gillespie, G.Y.4    Cheresh, D.A.5
  • 70
    • 0029929675 scopus 로고    scopus 로고
    • Migration of braintumor cells on extracellular matrix proteins in vitro correlates withtumor type and grade and involves αv and β1 integrins
    • Friedlander, D. R.; Zagzag, D.; Shiff, B.; Cohen, H.; Allen, J. C.; Kelly, P. J.; Grumet, M. Migration of braintumor cells on extracellular matrix proteins in vitro correlates withtumor type and grade and involves αv and β1 integrins. CancerRes., 1996, 56(8), 1939-1947.
    • (1996) CancerRes. , vol.56 , Issue.8 , pp. 1939-1947
    • Friedlander, D.R.1    Zagzag, D.2    Shiff, B.3    Cohen, H.4    Allen, J.C.5    Kelly, P.J.6    Grumet, M.7
  • 71
    • 0035866813 scopus 로고    scopus 로고
    • Sublethal irradiation promotesmigration and invasiveness of glioma cells
    • Wild-Bode, C.; Weller, M.; Rimner, A.; Dichgans, J.; Wick, W. Sublethal irradiation promotesmigration and invasiveness of glioma cells. Cancer Res., 2001, 61(6), 2744-2750.
    • (2001) Cancer Res. , vol.61 , Issue.6 , pp. 2744-2750
    • Wild-Bode, C.1    Weller, M.2    Rimner, A.3    Dichgans, J.4    Wick, W.5
  • 72
    • 0027938974 scopus 로고
    • Association of focal adhesion kinasewith its potential substrate phosphatidylinositol 3-kinase
    • Chen, H.-C.; Guan, J.-L. Association of focal adhesion kinasewith its potential substrate phosphatidylinositol 3-kinase. Proc.Natl. Acad. Sci. USA, 1994, 91(21), 10148-10152.
    • (1994) Proc.Natl. Acad. Sci. USA , vol.91 , Issue.21 , pp. 10148-10152
    • Chen, H.-C.1    Guan, J.-L.2
  • 73
    • 0028173980 scopus 로고
    • Stable association of pp60src and pp59fyn with the focal adhesion-associated proteintyrosine kinase, pp125FAK
    • Cobb, B. S.; Schaller, M. D.; Leu, T. H.; Parsons, J. T. Stable association of pp60src and pp59fyn with the focal adhesion-associated proteintyrosine kinase, pp125FAK. Mol. Cell. Biol., 1994, 14(1), 147-155.
    • (1994) Mol. Cell. Biol. , vol.14 , Issue.1 , pp. 147-155
    • Cobb, B.S.1    Schaller, M.D.2    Leu, T.H.3    Parsons, J.T.4
  • 74
    • 0028122650 scopus 로고
    • Focal adhesion kinase and associated proteins
    • Schaller, M. D.; Thomas Parsons, J. Focal adhesion kinase and associated proteins. Curr. Opin. Cell Biol., 1994, 6(5), 705-710.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , Issue.5 , pp. 705-710
    • Schaller, M.D.1    Thomas Parsons, J.2
  • 77
    • 0037191506 scopus 로고    scopus 로고
    • Inhibition of migration of humanglioblastoma cells by cerivastatin in association with focal adhesionkinase (FAK)
    • Obara, S.; Nakata, M.; Takeshima, H.; Kuratsu, J.-i.; Maruyama, I.; Kitajima, I. Inhibition of migration of humanglioblastoma cells by cerivastatin in association with focal adhesionkinase (FAK). Cancer Lett., 2002, 185(2), 153-161.
    • (2002) Cancer Lett. , vol.185 , Issue.2 , pp. 153-161
    • Obara, S.1    Nakata, M.2    Takeshima, H.3    Kuratsu, J.-I.4    Maruyama, I.5    Kitajima, I.6
  • 78
    • 0037784052 scopus 로고    scopus 로고
    • Geldanamycin inhibits migration of gliomacells in vitro: A potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion
    • Zagzag, D.; Nomura, M.; David, R. F.; Blanco, C. Y.; Gagner, J.-P.; Nomura, N.; Newcomb, E. W. Geldanamycin inhibits migration of gliomacells in vitro: A potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion. J. Cell. Physiol., 2003, 196(2), 394-402.
    • (2003) J. Cell. Physiol. , vol.196 , Issue.2 , pp. 394-402
    • Zagzag, D.1    Nomura, M.2    David, R.F.3    Blanco, C.Y.4    Gagner, J.-P.5    Nomura, N.6    Newcomb, E.W.7
  • 79
    • 0033564807 scopus 로고    scopus 로고
    • Malignantastrocytoma cell attachment and migration to various matrixproteins is differentially sensitive to phosphoinositide 3-OH kinaseinhibitors
    • Ling, J.; Liu, Z.; Wang, D.; Gladson, C. L. Malignantastrocytoma cell attachment and migration to various matrixproteins is differentially sensitive to phosphoinositide 3-OH kinaseinhibitors. J. Cell Biochem., 1999, 73(4), 533-544.
    • (1999) J. Cell Biochem. , vol.73 , Issue.4 , pp. 533-544
    • Ling, J.1    Liu, Z.2    Wang, D.3    Gladson, C.L.4
  • 81
    • 66249100268 scopus 로고    scopus 로고
    • The mechanicalrigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells
    • Ulrich, T. A.; de Juan Pardo, E. M.; Kumar, S. The mechanicalrigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res., 2009, 69(10), 4167-4174.
    • (2009) Cancer Res. , vol.69 , Issue.10 , pp. 4167-4174
    • Ulrich, T.A.1    de Juan Pardo, E.M.2    Kumar, S.3
  • 82
    • 33846253207 scopus 로고    scopus 로고
    • W.Tenascin-C stimulates glioma cell invasion through matrixmetalloproteinase-12
    • Sarkar, S.; Nuttall, R. K.; Liu, S.; Edwards, D. R.; Yong, V. W.Tenascin-C stimulates glioma cell invasion through matrixmetalloproteinase-12. Cancer Res., 2006, 66(24), 11771-11780.
    • (2006) Cancer Res. , vol.66 , Issue.24 , pp. 11771-11780
    • Sarkar, S.1    Nuttall, R.K.2    Liu, S.3    Edwards, D.R.4    Yong, V.5
  • 83
    • 33748476449 scopus 로고    scopus 로고
    • Glioma-produced extracellular matrix influencesbrain tumor tropism of human neural stem cells
    • Ziu, M.; Schmidt, N. O.; Cargioli, T. G.; Aboody, K. S.; Black, P.M.; Carroll, R. S. Glioma-produced extracellular matrix influencesbrain tumor tropism of human neural stem cells. J. Neuro-Oncol., 2006, 79(2), 125-133.
    • (2006) J. Neuro-Oncol. , vol.79 , Issue.2 , pp. 125-133
    • Ziu, M.1    Schmidt, N.O.2    Cargioli, T.G.3    Aboody, K.S.4    Black, P.M.5    Carroll, R.S.6
  • 84
    • 31544447172 scopus 로고    scopus 로고
    • Angiopoietin 2 induces glioma cell invasion bystimulating matrix metalloprotease 2 expression through thealphavbeta1 integrin and focal adhesion kinase signaling pathway
    • Hu, B.; Jarzynka, M. J.; Guo, P.; Imanishi, Y.; Schlaepfer, D. D.; Cheng, S. Y. Angiopoietin 2 induces glioma cell invasion bystimulating matrix metalloprotease 2 expression through thealphavbeta1 integrin and focal adhesion kinase signaling pathway.Cancer Res., 2006, 66(2), 775-83.
    • (2006) Cancer Res. , vol.66 , Issue.2 , pp. 775-783
    • Hu, B.1    Jarzynka, M.J.2    Guo, P.3    Imanishi, Y.4    Schlaepfer, D.D.5    Cheng, S.Y.6
  • 85
    • 12144286634 scopus 로고    scopus 로고
    • Cyr61 is overexpressed ingliomas and involved in integrin-linked kinase-mediated Akt and β-catenin-TCF/Lef signaling pathways
    • Xie, D.; Yin, D.; Tong, X.; O'Kelly, J.; Mori, A.; Miller, C.; Black, K.; Gui, D.; Said, J. W.; Koeffler, H. P. Cyr61 is overexpressed ingliomas and involved in integrin-linked kinase-mediated Akt and β-catenin-TCF/Lef signaling pathways. Cancer Res., 2004, 64(6), 1987-1996.
    • (2004) Cancer Res. , vol.64 , Issue.6 , pp. 1987-1996
    • Xie, D.1    Yin, D.2    Tong, X.3    O'Kelly, J.4    Mori, A.5    Miller, C.6    Black, K.7    Gui, D.8    Said, J.W.9    Koeffler, H.P.10
  • 86
    • 71549129574 scopus 로고    scopus 로고
    • Galectin-1 is implicated in theprotein kinase C ε/vimentin-controlled trafficking of integrin-β1 inglioblastoma Cells
    • Fortin, S.; Mercier, M. L.; Camby, I.; Spiegl-Kreinecker, S.; Berger, W.; Lefranc, F.; Kiss, R. Galectin-1 is implicated in theprotein kinase C ε/vimentin-controlled trafficking of integrin-β1 inglioblastoma Cells. Brain Pathol., 2010, 20(1), 39-49.
    • (2010) Brain Pathol. , vol.20 , Issue.1 , pp. 39-49
    • Fortin, S.1    Mercier, M.L.2    Camby, I.3    Spiegl-Kreinecker, S.4    Berger, W.5    Lefranc, F.6    Kiss, R.7
  • 87
    • 78649804159 scopus 로고    scopus 로고
    • PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration bysuppressing SHC-RAF-ERK and AKT signaling
    • Advance Access
    • Thomas, S. L.; Alam, R.; Lemke, N.; Schultz, L. R.; Gutierrez, J.A.; Rempel, S. A. PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration bysuppressing SHC-RAF-ERK and AKT signaling. Neuro-Oncology, 2010, Advance Access, noq048.
    • (2010) Neuro-Oncology
    • Thomas, S.L.1    Alam, R.2    Lemke, N.3    Schultz, L.R.4    Gutierrez, J.A.5    Rempel, S.A.6
  • 89
    • 0035947766 scopus 로고    scopus 로고
    • Membrane-type 1 matrix metalloproteinasecleaves Cd44 and promotes cell migration
    • Kajita, M.; Itoh, Y.; Chiba, T.; Mori, H.; Okada, A.; Kinoh, H.; Seiki, M. Membrane-type 1 matrix metalloproteinasecleaves Cd44 and promotes cell migration. J. Cell Biol., 2001, 153(5), 893-904.
    • (2001) J. Cell Biol. , vol.153 , Issue.5 , pp. 893-904
    • Kajita, M.1    Itoh, Y.2    Chiba, T.3    Mori, H.4    Okada, A.5    Kinoh, H.6    Seiki, M.7
  • 90
    • 0032926177 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase 9to the cell surface provides a mechanism for CD44-mediated tumorinvasion
    • Yu, Q.; Stamenkovic, I. Localization of matrix metalloproteinase 9to the cell surface provides a mechanism for CD44-mediated tumorinvasion. Genes Dev., 1999, 13(1), 35-48.
    • (1999) Genes Dev. , vol.13 , Issue.1 , pp. 35-48
    • Yu, Q.1    Stamenkovic, I.2
  • 92
    • 0024519677 scopus 로고
    • Cellularreceptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulinsuperfamily
    • Mendelsohn, C. L.; Wimmer, E.; Racaniello, V. R. Cellularreceptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulinsuperfamily. Cell, 1989, 56(5), 855-865.
    • (1989) Cell , vol.56 , Issue.5 , pp. 855-865
    • Mendelsohn, C.L.1    Wimmer, E.2    Racaniello, V.R.3
  • 94
    • 28244458116 scopus 로고    scopus 로고
    • CD155/PVR enhances glioma cell dispersal by regulatingadhesion signaling and focal adhesion dynamics
    • Sloan, K. E.; Stewart, J. K.; Treloar, A. F.; Matthews, R. T.; Jay, D.G. CD155/PVR enhances glioma cell dispersal by regulatingadhesion signaling and focal adhesion dynamics. Cancer Res., 2005, 65(23), 10930-7.
    • (2005) Cancer Res. , vol.65 , Issue.23 , pp. 10930-10937
    • Sloan, K.E.1    Stewart, J.K.2    Treloar, A.F.3    Matthews, R.T.4    Jay, D.G.5
  • 95
    • 28244458116 scopus 로고    scopus 로고
    • CD155/PVR enhances glioma cell dispersal by regulatingadhesion signaling and focal adhesion dynamics
    • Sloan, K. E.; Stewart, J. K.; Treloar, A. F.; Matthews, R. T.; Jay, D.G. CD155/PVR enhances glioma cell dispersal by regulatingadhesion signaling and focal adhesion dynamics. Cancer Res., 2005, 65(23), 10930-10937.
    • (2005) Cancer Res. , vol.65 , Issue.23 , pp. 10930-10937
    • Sloan, K.E.1    Stewart, J.K.2    Treloar, A.F.3    Matthews, R.T.4    Jay, D.G.5
  • 96
    • 0037447318 scopus 로고    scopus 로고
    • L.; Spaziante, R.; Florio, T.; Schettini, G.Stromal cell-derived factor 1α stimulates human glioblastoma cellgrowth through the activation of both extracellular signal-regulatedkinases 1/2 and Akt
    • Barbero, S.; Bonavia, R.; Bajetto, A.; Porcile, C.; Pirani, P.; Ravetti, J. L.; Zona, G. L.; Spaziante, R.; Florio, T.; Schettini, G.Stromal cell-derived factor 1α stimulates human glioblastoma cellgrowth through the activation of both extracellular signal-regulatedkinases 1/2 and Akt. Cancer Res., 2003, 63(8), 1969-1974.
    • (2003) Cancer Res. , vol.63 , Issue.8 , pp. 1969-1974
    • Barbero, S.1    Bonavia, R.2    Bajetto, A.3    Porcile, C.4    Pirani, P.5    Ravetti, J.L.6    Zona, G.7
  • 97
    • 38149098378 scopus 로고    scopus 로고
    • LRRC4inhibits human glioblastoma cells proliferation, invasion, and proMMP-2 activation by reducing SDF-1alpha/CXCR4-mediatedERK1/2 and Akt signaling pathways
    • Wu, M.; Chen, Q.; Li, D.; Li, X.; Li, X.; Huang, C.; Tang, Y.; Zhou, Y.; Wang, D.; Tang, K.; Cao, L.; Shen, S.; Li, G. LRRC4inhibits human glioblastoma cells proliferation, invasion, and proMMP-2 activation by reducing SDF-1alpha/CXCR4-mediatedERK1/2 and Akt signaling pathways. J. Cell. Biochem., 2008, 103(1), 245-255.
    • (2008) J. Cell. Biochem. , vol.103 , Issue.1 , pp. 245-255
    • Wu, M.1    Chen, Q.2    Li, D.3    Li, X.4    Li, X.5    Huang, C.6    Tang, Y.7    Zhou, Y.8    Wang, D.9    Tang, K.10    Cao, L.11    Shen, S.12    Li, G.13
  • 98
    • 27944455701 scopus 로고    scopus 로고
    • The chemokine stromal cellderived factor-1 (CXCL12) promotes glioma invasiveness throughMT2-matrix metalloproteinase
    • Zhang, J.; Sarkar, S.; Yong, V. W. The chemokine stromal cellderived factor-1 (CXCL12) promotes glioma invasiveness throughMT2-matrix metalloproteinase. Carcinogenesis, 2005, 26(12), 2069-2077.
    • (2005) Carcinogenesis , vol.26 , Issue.12 , pp. 2069-2077
    • Zhang, J.1    Sarkar, S.2    Yong, V.W.3
  • 100
    • 27144452068 scopus 로고    scopus 로고
    • Role of p38 mitogen-activated kinase and c-Jun terminal kinase inmigration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells
    • Malchinkhuu, E.; Sato, K.; Horiuchi, Y.; Mogi, C.; Ohwada, S.; Ishiuchi, S.; Saito, N.; Kurose, H.; Tomura, H.; Okajima, F. Role of p38 mitogen-activated kinase and c-Jun terminal kinase inmigration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells. Oncogene, 2005, 24(44), 6676-6688.
    • (2005) Oncogene , vol.24 , Issue.44 , pp. 6676-6688
    • Malchinkhuu, E.1    Sato, K.2    Horiuchi, Y.3    Mogi, C.4    Ohwada, S.5    Ishiuchi, S.6    Saito, N.7    Kurose, H.8    Tomura, H.9    Okajima, F.10
  • 104
    • 0037144496 scopus 로고    scopus 로고
    • Protein kinase C-ζ regulates transcription of the matrix metalloproteinase-9 geneinduced by IL-1 and TNF-α in glioma cells via NF-κ B
    • Esteve, P. O.; Chicoine, E.; Robledo, O.; Aoudjit, F.; Descoteaux, A.; Potworowski, E. F.; St-Pierre, Y. Protein kinase C-ζ regulates transcription of the matrix metalloproteinase-9 geneinduced by IL-1 and TNF-α in glioma cells via NF-κ B. J. Biolo.Chem., 2002, 277(38), 35150-35155.
    • (2002) J. Biolo.Chem. , vol.277 , Issue.38 , pp. 35150-35155
    • Esteve, P.O.1    Chicoine, E.2    Robledo, O.3    Aoudjit, F.4    Descoteaux, A.5    Potworowski, E.F.6    St-Pierre, Y.7
  • 105
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer, P. H. CD95's deadly mission in the immune system.Nature, 2000, 407 (6805), 789-795.
    • (2000) Nature , vol.407 , Issue.6805 , pp. 789-795
    • Krammer, P.H.1
  • 106
    • 0027145632 scopus 로고
    • Molecular cloningand expression of the fas ligand, a novel member of the tumornecrosis factor family
    • Suda, T.; Takahashi, T.; Golstein, P.; Nagata, S. Molecular cloningand expression of the fas ligand, a novel member of the tumornecrosis factor family. Cell 1993, 75 (6), 1169-1178.
    • (1993) Cell , vol.75 , Issue.6 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 107
    • 4143108125 scopus 로고    scopus 로고
    • CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells
    • Barnhart, B. C.; Legembre, P.; Pietras, E.; Bubici, C.; Franzoso, G.; Peter, M. E. CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. EMBO J, 2004, 23(15), 3175-85.
    • (2004) EMBO J , vol.23 , Issue.15 , pp. 3175-3185
    • Barnhart, B.C.1    Legembre, P.2    Pietras, E.3    Bubici, C.4    Franzoso, G.5    Peter, M.E.6
  • 108
    • 61449148439 scopus 로고    scopus 로고
    • TNFlikeweak inducer of apoptosis (TWEAK) activatesproinflammatory signaling pathways and gene expression throughthe activation of TGF-{beta}-activated kinase 1
    • Kumar, M.; Makonchuk, D. Y.; Li, H.; Mittal, A.; Kumar, A. TNFlikeweak inducer of apoptosis (TWEAK) activatesproinflammatory signaling pathways and gene expression throughthe activation of TGF-{beta}-activated kinase 1. J. Immunol., 2009, 182(4), 2439-2448.
    • (2009) J. Immunol. , vol.182 , Issue.4 , pp. 2439-2448
    • Kumar, M.1    Makonchuk, D.Y.2    Li, H.3    Mittal, A.4    Kumar, A.5
  • 109
    • 77953732982 scopus 로고    scopus 로고
    • Ubiquitin-specific protease 8 links the PTEN-Akt-AIP4 pathway to the control of FLIPS stability and TRAILsensitivity in glioblastoma multiforme
    • Panner, A.; Crane, C. A.; Weng, C.; Feletti, A.; Fang, S.; Parsa, A.T.; Pieper, R. O. Ubiquitin-specific protease 8 links the PTEN-Akt-AIP4 pathway to the control of FLIPS stability and TRAILsensitivity in glioblastoma multiforme. Cancer Res., 2010, 70(12), 5046-53.
    • (2010) Cancer Res. , vol.70 , Issue.12 , pp. 5046-5053
    • Panner, A.1    Crane, C.A.2    Weng, C.3    Feletti, A.4    Fang, S.5    Parsa, A.T.6    Pieper, R.O.7
  • 110
    • 0036946575 scopus 로고    scopus 로고
    • Microglia promote gliomamigration
    • Bettinger, I.; Thanos, S.; Paulus, W. Microglia promote gliomamigration. Acta Neuropathol., 2002, 103(4), 351-355.
    • (2002) Acta Neuropathol. , vol.103 , Issue.4 , pp. 351-355
    • Bettinger, I.1    Thanos, S.2    Paulus, W.3
  • 114
    • 77954391616 scopus 로고    scopus 로고
    • N.IL-27 inhibits OSM-mediated TNF-alpha and iNOS geneexpression in microglia
    • Baker, B. J.; Park, K. W.; Qin, H.; Ma, X.; Benveniste, E. N.IL-27 inhibits OSM-mediated TNF-alpha and iNOS geneexpression in microglia. Glia, 2010, 58(9), 1082-1093.
    • (2010) Glia , vol.58 , Issue.9 , pp. 1082-1093
    • Baker, B.J.1    Park, K.W.2    Qin, H.3    Ma, X.4    Benveniste, E.5
  • 115
    • 38449113410 scopus 로고    scopus 로고
    • Oncostatin M-inducedgenes in human astrocytomas
    • Krona, A.; Aman, P.; Orndal, C.; Josefsson, A. Oncostatin M-inducedgenes in human astrocytomas. Int. J. Oncol., 2007, 31(6), 1457-63.
    • (2007) Int. J. Oncol. , vol.31 , Issue.6 , pp. 1457-1463
    • Krona, A.1    Aman, P.2    Orndal, C.3    Josefsson, A.4
  • 120
    • 77952863838 scopus 로고    scopus 로고
    • Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion invivo and impairs their ability to form tumor spheres
    • Mendez, O.; Zavadil, J.; Esencay, M.; Lukyanov, Y.; Santovasi, D.; Wang, S.-C.; Newcomb, E. W.; Zagzag, D. Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion invivo and impairs their ability to form tumor spheres. Mol. Cancer, 2010, 9, 133.
    • (2010) Mol. Cancer , vol.9 , pp. 133
    • Mendez, O.1    Zavadil, J.2    Esencay, M.3    Lukyanov, Y.4    Santovasi, D.5    Wang, S.-C.6    Newcomb, E.W.7    Zagzag, D.8
  • 121
    • 77955475753 scopus 로고    scopus 로고
    • IGFBP2 promotesglioma tumor stem cell expansion and survival
    • Hsieh, D.; Hsieh, A.; Stea, B.; Ellsworth, R. IGFBP2 promotesglioma tumor stem cell expansion and survival. Biochem. Biophys.Res. Commun., 2010, 397(2), 367-72.
    • (2010) Biochem. Biophys.Res. Commun. , vol.397 , Issue.2 , pp. 367-372
    • Hsieh, D.1    Hsieh, A.2    Stea, B.3    Ellsworth, R.4
  • 124
    • 5044227347 scopus 로고    scopus 로고
    • K.Identification of two contiguous minimally deleted regions onchromosome 1p36.31-p36.32 in oligodendroglial tumours
    • Dong, Z.; Pang, J. S.; Ng, M. H.; Poon, W. S.; Zhou, L.; Ng, H. K.Identification of two contiguous minimally deleted regions onchromosome 1p36.31-p36.32 in oligodendroglial tumours. Br. J.Cancer, 2004, 91(6), 1105-11.
    • (2004) Br. J.Cancer , vol.91 , Issue.6 , pp. 1105-1111
    • Dong, Z.1    Pang, J.S.2    Ng, M.H.3    Poon, W.S.4    Zhou, L.5    Ng, H.6
  • 126
  • 127
    • 0031943089 scopus 로고    scopus 로고
    • E-Cadherin inhuman brain tumours: Loss of immunoreactivity in malignantmeningiomas
    • Schwechheimer, K.; Zhou, L.; Birchmeier, W. E-Cadherin inhuman brain tumours: loss of immunoreactivity in malignantmeningiomas. Virch. Arch., 1998, 432 (2), 163-7.
    • (1998) Virch. Arch. , vol.432 , Issue.2 , pp. 163-167
    • Schwechheimer, K.1    Zhou, L.2    Birchmeier, W.3
  • 128
    • 0035990052 scopus 로고    scopus 로고
    • Relationshipbetween the expression of E-, N-cadherins and beta-catenin and tumor grade in astrocytomas
    • Utsuki, S.; Sato, Y.; Oka, H.; Tsuchiya, B.; Suzuki, S.; Fujii, K. Relationshipbetween the expression of E-, N-cadherins and beta-catenin and tumor grade in astrocytomas. J. Neurooncol., 2002, 57(3), 187-92.
    • (2002) J. Neurooncol. , vol.57 , Issue.3 , pp. 187-192
    • Utsuki, S.1    Sato, Y.2    Oka, H.3    Tsuchiya, B.4    Suzuki, S.5    Fujii, K.6
  • 129
    • 12344311232 scopus 로고    scopus 로고
    • Invasive meningioma is associated with alow expression of E-cadherin and beta-catenin
    • Utsuki, S.; Oka, H.; Sato, Y.; Kawano, N.; Tsuchiya, B.; Kobayashi, I.; Fujii, K. Invasive meningioma is associated with alow expression of E-cadherin and beta-catenin. Clin. Neuropathol., 2005, 24(1), 8-12.
    • (2005) Clin. Neuropathol. , vol.24 , Issue.1 , pp. 8-12
    • Utsuki, S.1    Oka, H.2    Sato, Y.3    Kawano, N.4    Tsuchiya, B.5    Kobayashi, I.6    Fujii, K.7
  • 132
    • 0029810634 scopus 로고    scopus 로고
    • Constitutiveactivation of c-Met in liver metastatic B16 melanoma cells dependson both substrate adhesion and cell density and is regulated by acytosolic tyrosine phosphatase activity
    • Rusciano, D.; Lorenzoni, P.; Burger, M. M. Constitutiveactivation of c-Met in liver metastatic B16 melanoma cells dependson both substrate adhesion and cell density and is regulated by acytosolic tyrosine phosphatase activity. J. Biol. Chem., 1996, 271(34), 20763-20769.
    • (1996) J. Biol. Chem. , vol.271 , Issue.34 , pp. 20763-20769
    • Rusciano, D.1    Lorenzoni, P.2    Burger, M.M.3
  • 133
    • 0029670904 scopus 로고    scopus 로고
    • Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosinephosphorylation of PDGF beta-receptors
    • Sundberg, C.; Rubin, K. Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosinephosphorylation of PDGF beta-receptors. J. Cell Biol., 1996, 132(4), 741-752.
    • (1996) J. Cell Biol. , vol.132 , Issue.4 , pp. 741-752
    • Sundberg, C.1    Rubin, K.2
  • 134
    • 0032538798 scopus 로고    scopus 로고
    • Integrins induceactivation of EGF receptor: Role in MAP kinase induction and adhesion-dependent cell survival
    • Moro, L.; Venturino, M.; Bozzo, C.; Silengo, L.; Altruda, F.; Beguinot, L.; Tarone, G.; Defilippi, P. Integrins induceactivation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival. EMBO J., 1998, 17(22), 6622-6632.
    • (1998) EMBO J. , vol.17 , Issue.22 , pp. 6622-6632
    • Moro, L.1    Venturino, M.2    Bozzo, C.3    Silengo, L.4    Altruda, F.5    Beguinot, L.6    Tarone, G.7    Defilippi, P.8
  • 135
    • 0029759716 scopus 로고    scopus 로고
    • Cellularadherence elicits ligand-independent activation of the Met cellsurfacereceptor
    • Wang, R.; Kobayashi, R.; Bishop, J. M. Cellularadherence elicits ligand-independent activation of the Met cellsurfacereceptor. Proc. Natl. Acad. Sci. USA, 1996, 93(16), 8425-8430.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , Issue.16 , pp. 8425-8430
    • Wang, R.1    Kobayashi, R.2    Bishop, J.M.3
  • 136
    • 35048824758 scopus 로고    scopus 로고
    • Sphingolipid signaling pathways as potentialtherapeutic targets in gliomas
    • Van Brocklyn, J. R. Sphingolipid signaling pathways as potentialtherapeutic targets in gliomas. Mini Rev. Med. Chem., 2007, 7, 984-990.
    • (2007) Mini Rev. Med. Chem. , vol.7 , pp. 984-990
    • Van Brocklyn, J.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.