Identification of novel ErbB3-interacting factors using the split-ubiquitin membrane yeast two-hybrid system

Genome Research

Volumn 13, Issue 7, 2003, Pages 1744-1753

  Thaminy, Safia ^a   Auerbach, Daniel ^b   Arnoldo, Anthony ^a   Stagljar, Igor ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b DUALSYSTEMS BIOTECH AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR; MEMBRANE PROTEIN; RGS PROTEIN; UBIQUITIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BRAIN; CELL LINE; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GENE LIBRARY; GENETIC VECTORS; HUMANS; KIDNEY; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PROTEIN INTERACTION MAPPING; RATS; RECEPTOR, ERBB-3; RGS PROTEINS; SACCHAROMYCES CEREVISIAE; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN;

EUKARYOTA; MAMMALIA;

EID: 0037810425     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.1276503     Document Type: Article

References (42)

1. Amorino, G.P., Hamilton, V.M., Valerie, K., Dent, P., Lammering, G., and Schmidt-Ullrich, R.K. 2002. Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells. Mol. Biol. Cell 13: 2233-2244.
2. Aronheim, A., Engelberg, D., Li, N., al-Alawi, N., Schlessinger, J., and Karin, M. 1994. Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Cell 78: 949-961.
3. Auerbach, D., Galeuchet-Schenk, B., Hottiger, M.O., and Stagljar, I. 2002a. Genetic approaches to the identification of interactions between membrane proteins in yeast. J. Recept. Signal Transduct. Res. 22: 471-481.
4. Auerbach, D., Thaminy, S., Hottiger, M.O., and Stagljar, I. 2002b. The post-genomic era of interactive proteomics: Facts and perspectives. Proteomics 2: 611-623.
5. Beckmann, A.M. and Wilce, P.A. 1997. Egr transcription factors in the nervous system. Neurochem. Int. 31: 477-510.
6. Broder, Y.C., Katz, S., and Aronheim, A. 1998. The ras recruitment system, a novel approach to the study of protein-protein interactions. Curr. Biol. 8: 1121-1124.
7. Cervantes, S., Gonzalez-Duarte, R., and Marfany, G. 2001. Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer's disease. FEBS Lett. 505: 81-86.
8. David, N.E., Gee, M., Andersen, B., Naider, F., Thorner, J., and Stevens, R.C. 1997. Expression and purification of the Saccharomyces cerevisiae α-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor. J. Biol. Chem. 272: 15553-15561.
9. de Bono, J.S. and Rowinsky, E.K. 2002. The ErbB receptor-family: A therapeutic target for cancer. Trends Mol. Med. 8: S19-26.
10. Derrien, A. and Druey, K.M. 2001. RGS16 function is regulated by epidermal growth factor receptor-mediated tyrosine phosphorylation. J. Biol. Chem. 276: 48532-48538.
11. Diamonti, A.J., Guy, P.M., Ivanof, C., Wong, K., Sweeney, C., and Carraway, 3rd, K.L. 2002. An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels. Proc. Natl. Acad. Sci 99: 2866-2871.
12. Druey, K.M., Sullivan, B.M., Brown, D., Fischer, E.R., Watson, N., Blumer, K.J., Gerfen, C.R., Scheschonka, A., and Kehrl, J.H. 1998. Expression of GTPase-deficient Giα2 results in translocation of cytoplasmic RGS4 to the plasma membrane. J. Biol. Chem. 273: 18405-18410.
13. Dunnwald, M., Varshavsky, A., and Johnsson, N. 1999. Detection of transient in vivo interactions between substrate and transporter during protein translocation into the endoplasmic reticulum. Mol. Biol. Cell 10: 329-344.
14. Ehrhard, K.N., Jacoby, J.J., Fu, X.Y., Jahn, R., and Dohlman, H.G. 2000. Use of G-protein fusions to monitor integral membrane protein-protein interactions in yeast. Nat. Biotechnol. 18: 1075-1079.
15. Fields, S. and Song, O. 1989. A novel genetic system to detect protein-protein interactions. Nature 340: 245-246.
16. Hollinger, S. and Hepler, J.R. 2002. Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling. Pharmacol. Rev. 54: 527-559.
17. Hubsman, M., Yudkovsky, G., and Aronheim, A. 2001. A novel approach for the identification of protein-protein interaction with integral membrane proteins. Nucleic Acids Res. 29: E18.
18. Ito, T., Chiba, T., Ozawa, R., Yoshida, M., Hattori, M., and Sakaki, Y. 2001. A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc. Natl. Acad. Sci. 98: 4569-4574.
19. Johnsson, N. and Varshavsky, A. 1994. Split ubiquitin as a sensor of protein interactions in vivo. Proc. Natl. Acad. Sci. 91: 10340-10344.
20. Khachigian, L.M., Williams, A.J., and Collins, T. 1995. Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells. J. Biol. Chem. 270: 27679-27686.
21. Laser, H., Bongards, C., Schuller, J., Heck, S., Johnsson, N., and Lehming, N. 2000. A new screen for protein interactions reveals that the Saccharomyces cerevisiae high mobility group proteins Nhp6A/B are involved in the regulation of the GAL1 promoter. Proc. Natl. Acad. Sci. 97: 13732-13737.
22. Massaad, M.J. and Herscovics, A. 2001. Interaction of the endoplasmic reticulum α 1,2-mannosidase Mns1p with Rer1p using the split-ubiquitin system. J. Cell Sci. 114: 4629-4635.
23. Matheny, C., Day, M.L., and Milbrandt, J. 1994. The nuclear localization signal of NGFI-A is located within the zinc finger DNA binding domain. J. Biol. Chem. 269: 8176-8181.
24. Mumberg, D., Muller, R., and Funk, M. 1995. Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene 156: 119-122.
25. Olayioye, M.A., Neve, R.M., Lane, H.A., and Hynes, N.E. 2000. The ErbB signaling network: Receptor heterodimerization in development and cancer. EMBO J. 19: 3159-3167.
26. Pahl, P.M., Hodges, Y.K., Meltesen, L., Perryman, M.B., Horwitz, K.B., and Horwitz, L.D. 1998. ZNF207, a ubiquitously expressed zinc finger gene on chromosome 6p21.3. Genomics 53: 410-412.
27. Qiu, X.B. and Goldberg, A.L. 2002. Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3. Proc. Natl. Acad. Sci. 99: 14843-14848.
28. Reinders, A., Schulze, W., Thaminy, S., Stagljar, I., Frommer, W.B., and Ward, J.M. 2002. Intra-and intermolecular interactions in sucrose transporters at the plasma membrane detected by the split-ubiquitin system and functional assays. Structure 10: 763-772.
29. Riese II, D.J. and Stern, D.F. 1998. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 20: 41-48.
30. Serebriiskii, I., Estojak, J., Berman, M., and Golemis, E.A. 2000. Approaches to detecting false positives in yeast two-hybrid systems. Biotechniques 28: 328-330, 332-326.
31. Srinivasa, S.P., Bernstein, L.S., Blumer, K.J., and Linder, M.E. 1998. Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. 95: 5584-5589.
32. Stagljar, I. and Fields, S. 2002. Analysis of membrane protein interactions using yeast-based technologies. Trends Biochem. Sci. 27: 559-563.
33. Stagljar, I. and te Heesen, S. 2000. Detecting interactions between membrane proteins in vivo using chimeras. Methods Enzymol. 327: 190-198.
34. Stagljar, I., Korostensky, C., Johnsson, N., and te Heesen, S. 1998. A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo. Proc. Natl. Acad. Sci. 95: 5187-5192.
35. Thaminy, S. and Stagljar, I. 2002. The membrane-based yeast two-hybrid system. In Protein-protein interactions (ed. E. Golemis), pp. 395-405. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
36. Tsujimoto, Y., Numaga, T., Ohshima, K., Yano, M.A., Ohsawa, R., Goto, D., Naito, S., and Ishikawa, M. 2003. Arabidopsis tobomavirus multiplication (TOM) 2 locus encodes a transmembrane protein that interacts with TOM1. EMBO J. 22: 335-343.
37. Uetz, P., Giot, L., Cagney, G., Mansfield, T.A., Judson, R.S., Knight, J.R., Lockshon, D., Narayan, V., Srinivasan, M., Pochart, P., et al. 2000. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403: 623-627.
38. Varshavsky, A. 1996. The N-end rule: Functions, mysteries, uses. Proc. Natl. Acad. Sci. 93: 12142-12149.
39. Vojtek, A.B., Hollenberg, S.M., and Cooper, J.A. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74: 205-214.
40. von Mering, C., Krause, R., Snel, B., Cornell, M., Oliver, S.G., Fields, S., and Bork, P. 2002. Comparative assessment of large-scale data sets of protein-protein interactions. Nature 417: 399-403.
41. Wittke, S., Lewke, N., Muller, S., and Johnsson, N. 1999. Probing the molecular environment of membrane proteins in vivo. Mol. Biol. Cell 10: 2519-2530.
42. Yarden, Y. 2001. Biology of HER2 and its importance in breast cancer. Oncology 61: 1-13.