Blockade of the sonic hedgehog signalling pathway inhibits choroidal neovascularization in a laser-induced rat model

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 30, Issue 5, 2010, Pages 659-665

  He, Hua ^a   Zhang, Hong ^a   Li, Bin ^a   Li, Guigang ^a   Wang, Zhitao ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

choroidal neovascularization; hypoxia; ischemia; Sonic hedgehog; therapeutics

Indexed keywords

CYCLOPAMINE; HIF1A PROTEIN, RAT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MEMBRANE PROTEIN; PROTEIN; SIGNAL PEPTIDE; SONIC HEDGEHOG PROTEIN; SONIC HEDGEHOG PROTEIN, RAT; VASCULAR ENDOTHELIAL GROWTH FACTOR A, RAT; VASCULOTROPIN A; VERATRUM ALKALOID;

ANIMAL; ARTICLE; BROWN NORWAY RAT; DRUG ANTAGONISM; DRUG EFFECT; INTRAVITREAL DRUG ADMINISTRATION; LASER COAGULATION; MALE; METABOLISM; PATHOPHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SUBRETINAL NEOVASCULARIZATION;

ANIMALS; CHOROIDAL NEOVASCULARIZATION; HEDGEHOG PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRAVITREAL INJECTIONS; LASER COAGULATION; MALE; MEMBRANE PROTEINS; RATS; RATS, INBRED BN; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VERATRUM ALKALOIDS;

EID: 78649856111     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-010-0560-z     Document Type: Article

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